Determination of Residues in the Norepinephrine Transporter That Are Critical for Tricyclic Antidepressant Affinity

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 8254-8260

  Roubert, Christine ^a,d   Cox, Peter J ^b,e   Brüss, Michael ^c   Hamon, Michel ^b   Bönisch, Heinz ^c   Giros, Bruno ^a,b  

^a FACULTÉ DE MÉDECINE   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c UNIVERSITY OF BONN   (Germany)

^d SANOFI   (France)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIODIVERSITY; BIOLOGICAL MEMBRANES; CHEMICAL BONDS; MUTAGENESIS;

COCAINE;

PROTEINS;

AMPHETAMINE; CHIMERIC PROTEIN; COCAINE; DESIPRAMINE; DOPAMINE TRANSPORTER; NORADRENALIN TRANSPORTER; NORTRIPTYLINE; TRICYCLIC ANTIDEPRESSANT AGENT; CARRIER PROTEIN; COTRANSPORTER; DOPAMINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG PROTEIN BINDING; DRUG TARGETING; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR CLONING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; BINDING SITE; CHEMISTRY; GENETIC TRANSFECTION; METABOLISM; MOLECULAR GENETICS;

MAMMALIA;

AMINO ACID SEQUENCE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BINDING SITES; CARRIER PROTEINS; COCAINE; DESIPRAMINE; DOPAMINE; MOLECULAR SEQUENCE DATA; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; NORTRIPTYLINE; SYMPORTERS; TRANSFECTION;

EID: 0035896596     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009798200     Document Type: Article

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