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Volumn 74, Issue 4, 2003, Pages 811-825

The glycine transporter-1 inhibitors NFPS and Org 24461: A pharmacological study

Author keywords

Antipsychotic agents; Antipsychotic tests; Anxiolytic tests; Electroencephalogram; Glycine transporter 1 inhibitors; Negative symptoms of schizophrenia; NFPS; Org 24461; 3H Glycine efflux; 3H Glycine uptake

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ALX 5407; APOMORPHINE; BETA ADRENERGIC RECEPTOR; CLOZAPINE; DEXAMPHETAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; GLYCINE; GLYCINE DERIVATIVE; HALOPERIDOL; N METHYL N [(4 TRIFLUOROMETHYL)PHENOXY] 3 PHENYLPROPYLGLYCINE; N [3 (4' FLUOROPHENYL) 3 (4' PHENYLPHENOXY)PROPYL]SARCOSINE; ORG 24461; PHENCYCLIDINE; RISPERIDONE; SARCOSINE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; UNCLASSIFIED DRUG;

EID: 0037343294     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(02)01078-X     Document Type: Article
Times cited : (106)

References (93)
  • 1
    • 0027446493 scopus 로고
    • Neurotransmitter transporters: Recent progress
    • Adams S.G., Kuhar J. Neurotransmitter transporters: recent progress. Annu. Rev. Neurosci. 16:1993;73-93.
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 73-93
    • Adams, S.G.1    Kuhar, J.2
  • 2
    • 0034055690 scopus 로고    scopus 로고
    • Serotonin model of schizophrenia: Emerging role of glutamate mechanisms
    • Aghajanian G.K., Marek G.J. Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain Res. Rev. 31:2000;302-312.
    • (2000) Brain Res. Rev. , vol.31 , pp. 302-312
    • Aghajanian, G.K.1    Marek, G.J.2
  • 3
    • 0028932701 scopus 로고
    • Gene structure and glial expression of the glycine transporter GLYT1 in embryonic and adult rodents
    • Amara R.H., Sato K., Shimada S., Tohyama M., Puschel A.W., Betz H. Gene structure and glial expression of the glycine transporter GLYT1 in embryonic and adult rodents. J. Neurosci. 15:1995;2524-2532.
    • (1995) J. Neurosci. , vol.15 , pp. 2524-2532
    • Amara, R.H.1    Sato, K.2    Shimada, S.3    Tohyama, M.4    Puschel, A.W.5    Betz, H.6
  • 4
    • 0020629581 scopus 로고
    • The dissociative anesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-D-aspartate
    • Anis N.A., Berry S.C., Burton N.R., Lodge D. The dissociative anesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-D-aspartate. Br. J. Pharmacol. 79:1983;565-575.
    • (1983) Br. J. Pharmacol. , vol.79 , pp. 565-575
    • Anis, N.A.1    Berry, S.C.2    Burton, N.R.3    Lodge, D.4
  • 5
    • 0029165098 scopus 로고
    • Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine
    • Arnt J. Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine. Eur. J. Pharmacol. 283:1995;55-62.
    • (1995) Eur. J. Pharmacol. , vol.283 , pp. 55-62
    • Arnt, J.1
  • 6
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics?
    • Arnt J., Skarsfeldt T. Do novel antipsychotics have similar pharmacological characteristics? Neuropsychopharmacology. 18:1998;63-101.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 63-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 8
    • 0035206590 scopus 로고    scopus 로고
    • N[3-(4′-Fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport
    • Aubrey K.R., Vanderberg R.J. N[3-(4′-Fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport. Br. J. Pharmacol. 134:2001;1429-1436.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1429-1436
    • Aubrey, K.R.1    Vanderberg, R.J.2
  • 9
    • 0034988360 scopus 로고    scopus 로고
    • Continuous phencyclidine treatment induced schizophrenia-like hyperactivity of striatal dopamine release
    • Balla A., Koneru B., Smiley J., Sershen H., Javitt D.C. Continuous phencyclidine treatment induced schizophrenia-like hyperactivity of striatal dopamine release. Neuropsychopharmacology. 25:2001;157-164.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 157-164
    • Balla, A.1    Koneru, B.2    Smiley, J.3    Sershen, H.4    Javitt, D.C.5
  • 10
    • 0032415129 scopus 로고    scopus 로고
    • Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses
    • Berger A.J., Dieudonne S., Ascher P. Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses. J. Neurophysiol. 80:1998;3336-3340.
    • (1998) J. Neurophysiol. , vol.80 , pp. 3336-3340
    • Berger, A.J.1    Dieudonne, S.2    Ascher, P.3
  • 12
    • 0031916179 scopus 로고    scopus 로고
    • MCPP-induced anxiety in the light-dark box in rats - A new method for screening anxiolytic activity
    • Bilkei-Gorzo A., Gyertyan I., Levay G. mCPP-induced anxiety in the light-dark box in rats - a new method for screening anxiolytic activity. Psychopharmacology. 136:1998;291-298.
    • (1998) Psychopharmacology , vol.136 , pp. 291-298
    • Bilkei-Gorzo, A.1    Gyertyan, I.2    Levay, G.3
  • 14
    • 0032582785 scopus 로고    scopus 로고
    • Analysis of a gene encoding two glycine transporter variants reveals alternative promoter usage and a novel gene structure
    • Borowsky B., Hoffman B.J. Analysis of a gene encoding two glycine transporter variants reveals alternative promoter usage and a novel gene structure. J. Biol. Chem. 273:1998;29077-29085.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29077-29085
    • Borowsky, B.1    Hoffman, B.J.2
  • 15
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.1
  • 17
    • 0028785179 scopus 로고
    • New insights into the biology of schizophrenia through the mechanism of action of clozapine
    • Brunello N., Masotto C., Steardo L., Markstein R., Racagni G. New insights into the biology of schizophrenia through the mechanism of action of clozapine. Neuropharmacology. 15:1995;177-213.
    • (1995) Neuropharmacology , vol.15 , pp. 177-213
    • Brunello, N.1    Masotto, C.2    Steardo, L.3    Markstein, R.4    Racagni, G.5
  • 19
    • 0024247522 scopus 로고
    • The current status of the dopamine hypothesis of schizophrenia
    • Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology. 1:1988;179-186.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 179-186
    • Carlsson, A.1
  • 20
    • 0030423635 scopus 로고    scopus 로고
    • Effect of glycine on antidepressant- and anxiolytic-like action of L-aminocyclopropanecarboxylic acid (ACPC) in rats
    • Chojnacka-Wojcik E., Tatarczynska E., Deren-Wesolek A. Effect of glycine on antidepressant- and anxiolytic-like action of L-aminocyclopropanecarboxylic acid (ACPC) in rats. Pol. J. Pharmacol. 48:1996;627-629.
    • (1996) Pol. J. Pharmacol. , vol.48 , pp. 627-629
    • Chojnacka-Wojcik, E.1    Tatarczynska, E.2    Deren-Wesolek, A.3
  • 21
    • 0013874766 scopus 로고
    • Further pharmacologic studies and first clinical experience with the phencyclidine derivative C1-581
    • Corssen G., Domino E.F. Further pharmacologic studies and first clinical experience with the phencyclidine derivative C1-581. Anesth. Analg. 45:1966;29-40.
    • (1966) Anesth. Analg. , vol.45 , pp. 29-40
    • Corssen, G.1    Domino, E.F.2
  • 22
    • 0026011969 scopus 로고
    • Recovery of neuropsychological functions during reduction in use of phencyclidine
    • Cosgrove J., Newell T.G. Recovery of neuropsychological functions during reduction in use of phencyclidine. J. Clin. Psychol. 47:1991;159-169.
    • (1991) J. Clin. Psychol. , vol.47 , pp. 159-169
    • Cosgrove, J.1    Newell, T.G.2
  • 23
    • 0002730584 scopus 로고
    • Mesolimbic and extrapyramidal sites for the mediation of stereotyped behavior patterns and hyperactivity by amphetamine and apomorphine in the rat
    • Costall B., Naylor R.J. Mesolimbic and extrapyramidal sites for the mediation of stereotyped behavior patterns and hyperactivity by amphetamine and apomorphine in the rat. Adv. Behav. Biol. 21:1977;47-76.
    • (1977) Adv. Behav. Biol. , vol.21 , pp. 47-76
    • Costall, B.1    Naylor, R.J.2
  • 25
    • 0030044715 scopus 로고    scopus 로고
    • The glutamatergic dysfunction hypothesis for schizophrenia
    • Coyle J.T. The glutamatergic dysfunction hypothesis for schizophrenia. Harv. Rev. Psychiatry. 3:1996;241-253.
    • (1996) Harv. Rev. Psychiatry , vol.3 , pp. 241-253
    • Coyle, J.T.1
  • 26
  • 27
    • 0032429754 scopus 로고    scopus 로고
    • Glycine and N-methyl-D-aspartate receptors: Physiological significance and possible therapeutic applications
    • Danysz W., Parson C.G. Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. Pharmacol. Rev. 50:1998;597-664.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 597-664
    • Danysz, W.1    Parson, C.G.2
  • 28
    • 0026611274 scopus 로고
    • 3H]Glycine uptake in rat hippocampus: Kinetic analysis and autoradiographic localization
    • 3H]Glycine uptake in rat hippocampus: kinetic analysis and autoradiographic localization. Brain Res. 572:1992;154-163.
    • (1992) Brain Res. , vol.572 , pp. 154-163
    • Fedele, E.1    Foster, A.C.2
  • 29
    • 0027330266 scopus 로고
    • 3H]glycine uptake in rat forebrain: Cellular localization in the hippocampus
    • 3H]glycine uptake in rat forebrain: cellular localization in the hippocampus. Neurosci. Lett. 161:1993;4-8.
    • (1993) Neurosci. Lett. , vol.161 , pp. 4-8
    • Fedele, E.1    Smith, D.2    Foster, A.C.3
  • 30
    • 0024981014 scopus 로고
    • Glycine maintains excitement
    • Foster A.C., Kemp J.A. Glycine maintains excitement. Nature. 338:1989;377-378.
    • (1989) Nature , vol.338 , pp. 377-378
    • Foster, A.C.1    Kemp, J.A.2
  • 31
    • 0023273862 scopus 로고
    • The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain
    • Foster A.C., Wong E.H.F. The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain. Br. J. Pharmacol. 91:1987;403-409.
    • (1987) Br. J. Pharmacol. , vol.91 , pp. 403-409
    • Foster, A.C.1    Wong, E.H.F.2
  • 32
    • 0006199612 scopus 로고    scopus 로고
    • Effect of ORG 24598 on glycine levels in brain regions of freely moving rats
    • [Abst. 68.2]
    • Ge J., Hamilton W., Collie I., Shahid M., Hill D., Mason A.et al. Effect of ORG 24598 on glycine levels in brain regions of freely moving rats. Soc. Neurosci. 1999;165. [Abst. 68.2].
    • (1999) Soc. Neurosci. , pp. 165
    • Ge, J.1    Hamilton, W.2    Collie, I.3    Shahid, M.4    Hill, D.5    Mason, A.6
  • 33
    • 73049155988 scopus 로고
    • The isolation of nerve endings from brain: An electron microscopic study of cell fragments derived by homogenization and centrifugation
    • Gray E.G., Whittaker V.P. The isolation of nerve endings from brain: an electron microscopic study of cell fragments derived by homogenization and centrifugation. J. Anat. 96:1962;79-88.
    • (1962) J. Anat. , vol.96 , pp. 79-88
    • Gray, E.G.1    Whittaker, V.P.2
  • 34
    • 0018332473 scopus 로고
    • 3H-prazosin to rat brain alpha-adrenergic receptors
    • 3H-prazosin to rat brain alpha-adrenergic receptors. Eur. J. Pharmacol. 55:1979;323-326.
    • (1979) Eur. J. Pharmacol. , vol.55 , pp. 323-326
    • Greengrass, P.1    Brenner, R.2
  • 35
    • 0028921447 scopus 로고
    • Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a Phase IIa randomized trial
    • Grotta J., Clark W., Coull B., Pettigrew C., Mackay B., Goldstein L.B.et al. Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a Phase IIa randomized trial. Stroke. 26:1995;602-605.
    • (1995) Stroke , vol.26 , pp. 602-605
    • Grotta, J.1    Clark, W.2    Coull, B.3    Pettigrew, C.4    Mackay, B.5    Goldstein, L.B.6
  • 36
    • 0036267331 scopus 로고    scopus 로고
    • Ziprasidone. A review of its use in schizophrenia and schizoaffective disorder
    • Gunasekara N.S., Spencer C.M., Keating G.M. Ziprasidone. A review of its use in schizophrenia and schizoaffective disorder. Drugs. 62:2002;1217-1251.
    • (2002) Drugs , vol.62 , pp. 1217-1251
    • Gunasekara, N.S.1    Spencer, C.M.2    Keating, G.M.3
  • 37
    • 0026724509 scopus 로고
    • Dopamine efflux from striatum after chronic nicotine: Evidence for autoreceptor desensitization
    • Harsing L.G. Jr., Sershen H., Lajtha A. Dopamine efflux from striatum after chronic nicotine: evidence for autoreceptor desensitization. J. Neurochem. 59:1992;48-54.
    • (1992) J. Neurochem. , vol.59 , pp. 48-54
    • Harsing L.G., Jr.1    Sershen, H.2    Lajtha, A.3
  • 40
    • 0034972570 scopus 로고    scopus 로고
    • Pharmacological assessment of the role of glycine transporter GlyT-1 in mediating high affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes
    • Herdon H.J., Godfrey F.M., Brown A.M., Coulton S., Evans J.R., Cairns W.J. Pharmacological assessment of the role of glycine transporter GlyT-1 in mediating high affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes. Neuropharmacology. 41:2001;88-96.
    • (2001) Neuropharmacology , vol.41 , pp. 88-96
    • Herdon, H.J.1    Godfrey, F.M.2    Brown, A.M.3    Coulton, S.4    Evans, J.R.5    Cairns, W.J.6
  • 41
    • 0030480590 scopus 로고    scopus 로고
    • Glycinergic augmentation of NMDA receptor-mediated neurotransmission in the treatment of schizophrenia
    • Heresco-Levy U., Silipo G., Javitt D.C. Glycinergic augmentation of NMDA receptor-mediated neurotransmission in the treatment of schizophrenia. Psychopharmacol. Bull. 32:1996;731-740.
    • (1996) Psychopharmacol. Bull. , vol.32 , pp. 731-740
    • Heresco-Levy, U.1    Silipo, G.2    Javitt, D.C.3
  • 42
    • 0029098028 scopus 로고
    • Catalepsy as a rodent model for detecting antipsychotic drugs with extrapyramidal side effect liability
    • Hoffman D.C., Donovan H. Catalepsy as a rodent model for detecting antipsychotic drugs with extrapyramidal side effect liability. Psychopharmacology. 120:1995;128-133.
    • (1995) Psychopharmacology , vol.120 , pp. 128-133
    • Hoffman, D.C.1    Donovan, H.2
  • 43
    • 0031024622 scopus 로고    scopus 로고
    • Glycyldodecylamide, a phencyclidine behavioral antagonist, blocks cortical glycine uptake implication for schizophrenia and substance abuse
    • Javitt D.C., Frusciante M. Glycyldodecylamide, a phencyclidine behavioral antagonist, blocks cortical glycine uptake implication for schizophrenia and substance abuse. Psychopharmacology. 129:1997;96-98.
    • (1997) Psychopharmacology , vol.129 , pp. 96-98
    • Javitt, D.C.1    Frusciante, M.2
  • 44
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry. 148:1991;1301-1308.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 45
    • 0033558578 scopus 로고    scopus 로고
    • Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors
    • Javitt D.C., Balla A., Sershen H., Lajtha A. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors. Biol. Psychiatry. 45:1999;668-679.
    • (1999) Biol. Psychiatry , vol.45 , pp. 668-679
    • Javitt, D.C.1    Balla, A.2    Sershen, H.3    Lajtha, A.4
  • 46
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson J.W., Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 325:1987;529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 47
    • 0002154277 scopus 로고
    • New developments in dopamine and schizophrenia
    • F.E. Bloom, & D.J. Kupfer. New York: Raven Press
    • Kahn R.S., Davis K.L. New developments in dopamine and schizophrenia. Bloom F.E., Kupfer D.J. Psychopharmacology: the fourth generation of progress. 1995;1215-1228 Raven Press, New York.
    • (1995) Psychopharmacology: The fourth generation of progress , pp. 1215-1228
    • Kahn, R.S.1    Davis, K.L.2
  • 48
    • 0028061401 scopus 로고
    • Towards more effective antipsychotic treatment
    • Kane J.M., Freeman H.L. Towards more effective antipsychotic treatment. Br. J. Psychiatry. 165:1994;22-31.
    • (1994) Br. J. Psychiatry , vol.165 , pp. 22-31
    • Kane, J.M.1    Freeman, H.L.2
  • 50
    • 0028348479 scopus 로고
    • Cloning of the human glycine transporter type 1: Molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes
    • Kim K.M., Kingsmore S.F., Han H., Yang-Feng T.L., Godinot N., Seldin M.F.et al. Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes. Mol. Pharmacol. 45:1994;608-617.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 608-617
    • Kim, K.M.1    Kingsmore, S.F.2    Han, H.3    Yang-Feng, T.L.4    Godinot, N.5    Seldin, M.F.6
  • 51
    • 0028034559 scopus 로고
    • Effects of risperidone on phencyclidine-induced behaviors: Comparison with haloperidol and ritanserin
    • Kitaichi K., Yamada K., Hasegawa T., Furukawa H., Nabeshima T. Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin. J. Pharmacol. 66:1994;181-189.
    • (1994) J. Pharmacol. , vol.66 , pp. 181-189
    • Kitaichi, K.1    Yamada, K.2    Hasegawa, T.3    Furukawa, H.4    Nabeshima, T.5
  • 52
    • 0033626574 scopus 로고    scopus 로고
    • B receptor partial agonist, D-cycloserine, in rats. Pharmacological analysis
    • B receptor partial agonist, D-cycloserine, in rats. Pharmacological analysis. Psychopharmacology. 152:2000;224-228.
    • (2000) Psychopharmacology , vol.152 , pp. 224-228
    • Klodzinska, A.1    Chojnacka-Wojcik, E.2
  • 53
    • 0026677223 scopus 로고
    • The NMDA-receptor antagonist CPP abolishes neurogenic "wind-up pain" after intrathecal administration in humans
    • Kristensen J.D., Svensson B., Gordh T. The NMDA-receptor antagonist CPP abolishes neurogenic "wind-up pain" after intrathecal administration in humans. Pain. 51:1992;249-253.
    • (1992) Pain , vol.51 , pp. 249-253
    • Kristensen, J.D.1    Svensson, B.2    Gordh, T.3
  • 55
  • 56
    • 0027524992 scopus 로고
    • Understanding the mechanism of action of atypical antipsychotic drugs. A review of compounds in use and development
    • Lieberman J.A. Understanding the mechanism of action of atypical antipsychotic drugs. A review of compounds in use and development. Br. J. Psychiatry Suppl. 22:1993;7-18.
    • (1993) Br. J. Psychiatry Suppl. , vol.22 , pp. 7-18
    • Lieberman, J.A.1
  • 57
    • 84951384024 scopus 로고
    • Simplified method of evaluating dose-effect experiments
    • Litchfield J.T., Wilcoxon F. Simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:1949;99-113.
    • (1949) J. Pharmacol. Exp. Ther. , vol.96 , pp. 99-113
    • Litchfield, J.T.1    Wilcoxon, F.2
  • 58
    • 0026718599 scopus 로고
    • Characterization and autoradiographical localization of nonadrenoceptor idazoxan binding sites in the rat brain
    • Mallard N.J., Hudson A.L., Nutt D.J. Characterization and autoradiographical localization of nonadrenoceptor idazoxan binding sites in the rat brain. Br. J. Pharmacol. 106:1992;1019-1027.
    • (1992) Br. J. Pharmacol. , vol.106 , pp. 1019-1027
    • Mallard, N.J.1    Hudson, A.L.2    Nutt, D.J.3
  • 59
    • 0030754797 scopus 로고    scopus 로고
    • MK-801-induced hyperlocomotion: Differential effects of MDL 100,907, SDZ PSD 958 and raclopride
    • Martin P., Svensson A., Carllson A., Carlsson M.L. MK-801-induced hyperlocomotion: differential effects of MDL 100,907, SDZ PSD 958 and raclopride. Eur. J. Pharmacol. 335:1997;107-116.
    • (1997) Eur. J. Pharmacol. , vol.335 , pp. 107-116
    • Martin, P.1    Svensson, A.2    Carllson, A.3    Carlsson, M.L.4
  • 61
    • 0002629884 scopus 로고
    • Atypical antipsychotic drugs
    • F.E. Bloom, & D.J. Kupfer. New York: Raven Press
    • Meltzer H.Y. Atypical antipsychotic drugs. Bloom F.E., Kupfer D.J. Psychopharmacology: the fourth generation of progress. 1995;1277-1286 Raven Press, New York.
    • (1995) Psychopharmacology: The fourth generation of progress , pp. 1277-1286
    • Meltzer, H.Y.1
  • 62
    • 0032466835 scopus 로고    scopus 로고
    • S-16924 [(R)-2-[1-[2-(2,3-dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]- 1-(4-fluorophenyl)-ethanone], a novel, potential antipsychotic with marked serotonin1A agonist properties: II. Functional profile in comparison to clozapine and haloperidol
    • Millan M.J., Schreiber R., Dekeyne A., Rivet J.M., Bervoets K., Mavridis M.et al. S-16924 [(R)-2-[1-[2-(2,3-dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]- 1-(4-fluorophenyl)-ethanone], a novel, potential antipsychotic with marked serotonin1A agonist properties: II. Functional profile in comparison to clozapine and haloperidol. J. Pharmacol. Exp. Ther. 286:1998;1356-1373.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 1356-1373
    • Millan, M.J.1    Schreiber, R.2    Dekeyne, A.3    Rivet, J.M.4    Bervoets, K.5    Mavridis, M.6
  • 63
    • 0033015420 scopus 로고    scopus 로고
    • S-16924 [(R)-2-[1-[2-(2,3-dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]- 1-(4-fluorophenyl)-ethanone], a novel, potential antipsychotic with marked serotonin1A agonist properties: III. Anxiolytic actions in comparison with clozapine and haloperidol
    • Millan M.J., Brocco M., Gobert A., Schreiber R., Dekeyne A. S-16924 [(R)-2-[1-[2-(2,3-dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]- 1-(4-fluorophenyl)-ethanone], a novel, potential antipsychotic with marked serotonin1A agonist properties: III. Anxiolytic actions in comparison with clozapine and haloperidol. J. Pharmacol. Exp. Ther. 288:1999;1002-1014.
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 1002-1014
    • Millan, M.J.1    Brocco, M.2    Gobert, A.3    Schreiber, R.4    Dekeyne, A.5
  • 64
    • 0014353437 scopus 로고
    • Neural mechanisms of ketamine-induced anesthesia
    • Miyasaka M., Domino E.F. Neural mechanisms of ketamine-induced anesthesia. Neuropharmacology. 7:1968;557-573.
    • (1968) Neuropharmacology , vol.7 , pp. 557-573
    • Miyasaka, M.1    Domino, E.F.2
  • 65
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group of II metabotropic glutamate receptor agonist in rats
    • Moghaddam B., Adams B.W. Reversal of phencyclidine effects by a group of II metabotropic glutamate receptor agonist in rats. Science. 281:1998;1349-1352.
    • (1998) Science , vol.281 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 66
    • 84961008600 scopus 로고
    • Effects of antiparkinson drugs on a phenothiazine-induced catatonic reaction
    • Morpurgo C. Effects of antiparkinson drugs on a phenothiazine-induced catatonic reaction. Arch. Int. Pharmacodyn. 137:1962;84-88.
    • (1962) Arch. Int. Pharmacodyn. , vol.137 , pp. 84-88
    • Morpurgo, C.1
  • 68
    • 0032971559 scopus 로고    scopus 로고
    • Preferential inhibition of dizocilpine-induced hyperlocomotion by olanzapine
    • Ninan I., Kulkarni S.K. Preferential inhibition of dizocilpine-induced hyperlocomotion by olanzapine. Eur. J. Pharmacol. 368:1999;1-7.
    • (1999) Eur. J. Pharmacol. , vol.368 , pp. 1-7
    • Ninan, I.1    Kulkarni, S.K.2
  • 69
    • 0032467053 scopus 로고    scopus 로고
    • Glutamate in CNS disorders as a target for drug development: An update
    • Parsons C.G., Danysz W., Quack G. Glutamate in CNS disorders as a target for drug development: an update. Drug News Perspect. 11:1998;523-569.
    • (1998) Drug News Perspect. , vol.11 , pp. 523-569
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 70
    • 0021686458 scopus 로고
    • The binding of serotonergic ligands to the pocine chorioid plexus: Characterization of a new type of serotonin recognition site
    • Pazos A., Hoyer D., Palacios J.M. The binding of serotonergic ligands to the pocine chorioid plexus: characterization of a new type of serotonin recognition site. Eur. J. Pharmacol. 106:1985;539-546.
    • (1985) Eur. J. Pharmacol. , vol.106 , pp. 539-546
    • Pazos, A.1    Hoyer, D.2    Palacios, J.M.3
  • 71
    • 0022514849 scopus 로고
    • 1C binding sites in rat frontal cortex
    • 1C binding sites in rat frontal cortex. J. Neurochem. 47:1986;529-540.
    • (1986) J. Neurochem. , vol.47 , pp. 529-540
    • Peroutka, S.J.1
  • 72
    • 0035119996 scopus 로고    scopus 로고
    • Pharmacological characterization of locomotor sensitization induced by chronic phencyclidine administration
    • Phillips M., Wang C., Johnson K.M. Pharmacological characterization of locomotor sensitization induced by chronic phencyclidine administration. J. Pharmacol. Exp. Ther. 296:2001;905-913.
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 905-913
    • Phillips, M.1    Wang, C.2    Johnson, K.M.3
  • 73
    • 0032488929 scopus 로고    scopus 로고
    • Characterization of the 5′ region of the rat brain glycine transporter GLYT2 gene: Identification of a novel isoform
    • Pronce J., Poyatos I., Aragon C., Gimenez C., Zafra F. Characterization of the 5′ region of the rat brain glycine transporter GLYT2 gene: identification of a novel isoform. Neurosci. Lett. 242:1998;25-28.
    • (1998) Neurosci. Lett. , vol.242 , pp. 25-28
    • Pronce, J.1    Poyatos, I.2    Aragon, C.3    Gimenez, C.4    Zafra, F.5
  • 74
    • 0026727228 scopus 로고
    • Comparison of binding at strychnine-sensitive (inhibitory glycine receptor) and strychnine-insensitive (N-methyl-D-aspartate receptor) glycine binding sites
    • Pullan L.M., Powell R.J. Comparison of binding at strychnine-sensitive (inhibitory glycine receptor) and strychnine-insensitive (N-methyl-D-aspartate receptor) glycine binding sites. Neurosci. Lett. 148:1992;199-201.
    • (1992) Neurosci. Lett. , vol.148 , pp. 199-201
    • Pullan, L.M.1    Powell, R.J.2
  • 76
    • 0023892993 scopus 로고
    • Multiple sites for the regulation of the N-methyl-D-aspartate receptor
    • Reynolds I.J., Miller R.J. Multiple sites for the regulation of the N-methyl-D-aspartate receptor. Mol. Pharmacol. 325:1988;581-584.
    • (1988) Mol. Pharmacol. , vol.325 , pp. 581-584
    • Reynolds, I.J.1    Miller, R.J.2
  • 77
    • 0028818536 scopus 로고
    • Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C
    • Sato K., Adams R., Betz H., Schloss P. Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C. J. Neurochem. 65:1995;1967-1973.
    • (1995) J. Neurochem. , vol.65 , pp. 1967-1973
    • Sato, K.1    Adams, R.2    Betz, H.3    Schloss, P.4
  • 78
    • 0032732417 scopus 로고    scopus 로고
    • Changes in EEG spectral power in the prefrontal cortex of conscious rat elicited by drugs interaction with dopaminergic and noradrenergic transmission
    • Sebban C., Zang Q.X., Tesolin-Decros B., Millan M.J., Spedding M. Changes in EEG spectral power in the prefrontal cortex of conscious rat elicited by drugs interaction with dopaminergic and noradrenergic transmission. Br. J. Pharmacol. 128:1999;1045-1054.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1045-1054
    • Sebban, C.1    Zang, Q.X.2    Tesolin-Decros, B.3    Millan, M.J.4    Spedding, M.5
  • 80
    • 0026772797 scopus 로고
    • Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors
    • Smith K.E., Borden A., Hartig P.R., Branchek T., Weinshank R.L. Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors. Neuron. 8:1992;927-935.
    • (1992) Neuron , vol.8 , pp. 927-935
    • Smith, K.E.1    Borden, A.2    Hartig, P.R.3    Branchek, T.4    Weinshank, R.L.5
  • 81
    • 0033932747 scopus 로고    scopus 로고
    • D-Amino acids as putative neurotransmitters: Focus on D-serine
    • Snyder S.H., Kim P.M. D-Amino acids as putative neurotransmitters: focus on D-serine. Neurochem. Res. 25:2000;553-560.
    • (2000) Neurochem. Res. , vol.25 , pp. 553-560
    • Snyder, S.H.1    Kim, P.M.2
  • 82
    • 0032401099 scopus 로고    scopus 로고
    • Serotonin and schizophrenia
    • Tamminga C.A. Serotonin and schizophrenia. Biol. Psychiatry. 44:1998;1079-1080.
    • (1998) Biol. Psychiatry , vol.44 , pp. 1079-1080
    • Tamminga, C.A.1
  • 83
    • 0031979134 scopus 로고    scopus 로고
    • Schizophrenia and glutamatergic transmission
    • Tamminga C.A. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurobiol. 12:1998;21-36.
    • (1998) Crit. Rev. Neurobiol. , vol.12 , pp. 21-36
    • Tamminga, C.A.1
  • 84
    • 0022611408 scopus 로고
    • Antagonism of phencyclidine-induced hyperactivity by glycine in mice
    • Toth E., Lajtha A. Antagonism of phencyclidine-induced hyperactivity by glycine in mice. Neurochem. Res. 11:1986;393-400.
    • (1986) Neurochem. Res. , vol.11 , pp. 393-400
    • Toth, E.1    Lajtha, A.2
  • 85
    • 0022472786 scopus 로고
    • Effect of glycine derivatives on behavioral changes induced by 3-mercaptopropionic acid or phencyclidine in mice
    • Toth E., Weiss B., Banay-Schwartz M., Lajtha A. Effect of glycine derivatives on behavioral changes induced by 3-mercaptopropionic acid or phencyclidine in mice. Psychol. Psychiatr. Behav. 11:1986;1-9.
    • (1986) Psychol. Psychiatr. Behav. , vol.11 , pp. 1-9
    • Toth, E.1    Weiss, B.2    Banay-Schwartz, M.3    Lajtha, A.4
  • 86
    • 0032403626 scopus 로고    scopus 로고
    • D-Serine added to antipsychotics for the treatment of schizophrenia
    • Tsai G., Yang P., Chung L.C., Lange N., Coyle J.T. D-Serine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry. 44:1998;1081-1089.
    • (1998) Biol. Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 87
    • 0026458644 scopus 로고
    • Transport explosion: Update on uptake
    • Uhl G.R., Hartig P.R. Transport explosion: update on uptake. Trends Pharmacol. Sci. 13:1992;421-425.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 421-425
    • Uhl, G.R.1    Hartig, P.R.2
  • 88
    • 0015004136 scopus 로고
    • A simple and reliable conflict procedure for testing antianxiety agents
    • Vogel J.R., Beer B., Clody D.E. A simple and reliable conflict procedure for testing antianxiety agents. Psychopharmacologia (Berl.). 21:1971;1-7.
    • (1971) Psychopharmacologia (Berl.) , vol.21 , pp. 1-7
    • Vogel, J.R.1    Beer, B.2    Clody, D.E.3
  • 89
    • 0024314278 scopus 로고
    • Interaction of permanently charged chlorpromazine and dopamine analogs with the striatal D-1 dopaminergic receptor
    • Wallace R.A., Wallace L., Harrold M., Miller D., Uretsky N.J. Interaction of permanently charged chlorpromazine and dopamine analogs with the striatal D-1 dopaminergic receptor. Biochem. Pharmacol. 38:1989;2019-2025.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 2019-2025
    • Wallace, R.A.1    Wallace, L.2    Harrold, M.3    Miller, D.4    Uretsky, N.J.5
  • 90
    • 0027189962 scopus 로고
    • Effects of four antipsychotics on punished responding in rats
    • Wiley L., Compton A.D., Porter J.H. Effects of four antipsychotics on punished responding in rats. Pharmacol. Biochem. Behav. 45:1993;263-267.
    • (1993) Pharmacol. Biochem. Behav. , vol.45 , pp. 263-267
    • Wiley, L.1    Compton, A.D.2    Porter, J.H.3
  • 91
    • 0025155556 scopus 로고
    • Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex
    • Winslow I.T., Insel T.R., Trullas R., Skolnick P. Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex. Eur. J. Pharmacol. 190:1990;11-21.
    • (1990) Eur. J. Pharmacol. , vol.190 , pp. 11-21
    • Winslow, I.T.1    Insel, T.R.2    Trullas, R.3    Skolnick, P.4


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