Capsaicin activated currents in rat dorsal root ganglion cells

Pain

Volumn 64, Issue 1, 1996, Pages 191-195

  Liu, L ^a   Wang, Y ^a   Simon, Sidney A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Neuron; Pain; Patch clamp; Taste; Thermoreception

Indexed keywords

CAPSAICIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ION CURRENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

EID: 0030070940     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3959(94)00097-2     Document Type: Article

References (16)

1. Bevan, S., Hothi, S., Hughes, G., James, I.F., Rang, H.P., Shah, K., Walpole, C.S.J. and Yeats, J.C., Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin, Br. J. Pharmacol., 107 (1992) 544-552.
2. Bevan, S. and Yeats, J., Protons activate a cation conductance in a subpopulation of rat dorsal root ganglion neurones, J. Physiol., 433 (1991) 145-151.
3. Bevan, S. and Docherty, R.J., Cellular mechanisms of the action of capsaicin. In: J. Wood (Ed.), Capsaicin in the Study of Pain. Academic Press, London, 1993, pp. 27-44.
4. Holzer, P., Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons, Pharmacol. Rev., 43 (1991) 143-201.
5. Ikemoto, Y. and Akaike, N., Kinetic analysis of acetylcholine-induced chloride current in isolated Aplysia neurones, Pflugers Arch., 412 (1988a) 240-247.
6. Ikemoto, Y., Akaike, N. and Ono, K., Kinetic analysis of glutamate-induced current in Aplysia neurones: a 'concentration clamp' study, Eur. J. Pharm., 150 (1988b) 303-311.
7. Kopsis, P.A., Desensitization of the Capsaicin Activated Currents in Rat Dorsal Root Ganglion. Ph.D. Thesis, University of North Carolina, 1995.
8. Liu, L. and Simon, S.A., A rapid capsaicin-activated current in rat trigeminal ganglion neurons, Proc. Natl. Acad. Sci. (USA), 91 (1994) 738-741.
9. Maggi, C.A., Capsaicin and primary afferent neurons: from basic science to human therapy?, J. Nerv. Syst., 33 (1992) 1-14.
10. Marsh, S.J., Stanefeld, C.E., Brown, D.A., Davey, R. and McCarthy, D., The mechanism and action of capsaicin on sensory C-type neurons and their axons in vitro, Neuroscience, 23 (1987) 275-289.
11. Petersen, M. and LaMotte, R.H., Relationships between capsaicin sensitivity of mammalian sensory neurons, cell size and type of voltage gated Ca-currents, Brain Res., 561 (1991) 20-26.
12. Petersen, M. and LaMotte, R.H., Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells, Pain, 54 (1993) 37-42.
13. Seno, N. and Dray, A., Capsaicin-induced activation of fine afferent fibers from rat skin in vitro, Neuroscience, 55 (1993) 563-569.
14. Szallasi, A. and Blumberg, P.M., Mechanisms and therapeutic potential of vanilloids (capsaicin-like molecules), Adv. Pharmacol., 24 (1993) 123-155.
15. Szolcanyi, J., Capsaicin, irritation and desensitization. In: B.G. Green, J.R. Mason and M.R. Kare (Eds.), Chemical Senses. Marcel Dekker, New York, 1990, pp. 141-168.
16. Szolcsanyi, J., Actions of capsaicin on sensory receptors. In: J. Wood (Eds.), Capsaicin in the Study of Pain. Academic Press, London, 1993, pp. 1-26.