Identification of Species-specific Determinants of the Action of the Antagonist Capsazepine and the Agonist PPAHV on TRPV1

Journal of Biological Chemistry

Volumn 279, Issue 17, 2004, Pages 17165-17172

  Phillips, Elsa ^a   Reeve, Alison ^a   Bevan, Stuart ^a   McIntyre, Peter ^a  

^a Novatis Inst for Medical Sciences   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HUMAN ENGINEERING; IONS; PH EFFECTS;

HUMAN RECEPTORS; ION CHANNELS;

BIOCHEMISTRY;

CAPSAICIN; CAPSAZEPINE; HOMOVANILLIC ACID; ISOLEUCINE; LEUCINE; METHIONINE; OLVANIL; PHORBOL 12 PHENYLACETATE 13 ACETATE 20 HOMOVANILLATE; RESINIFERATOXIN; UNCLASSIFIED DRUG; VALINE; VANILLOID RECEPTOR 1;

ACIDITY; AMINO ACID SUBSTITUTION; AMPLITUDE MODULATION; ARTICLE; BINDING AFFINITY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; GUINEA PIG; HEAT; HUMAN; IC 50; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CAPSAICIN; CHO CELLS; CRICETINAE; DITERPENES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GUINEA PIGS; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; IONS; KINETICS; LIGANDS; METHIONINE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENOTYPE; PHORBOL ESTERS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, DRUG; SPECIES SPECIFICITY; TIME FACTORS;

CAVIA PORCELLUS; SUS SCROFA;

EID: 2342439775     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313328200     Document Type: Article

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