BH3-domain mimetic compound BH3I-2′ induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria

British Journal of Haematology

Volumn 121, Issue 2, 2003, Pages 332-340

  Feng, Wan Yu ^a,b   Liu, Feng Ting ^a   Patwari, Yasmeen ^a   Agrawal, Samir G ^a   Newland, Adrian C ^a   Jia, Li ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; Bcl XL; BH3; Inner and outer mitochondrial membrane

Indexed keywords

3 IODO 5 CHLORO N [2 CHLORO 5 [(4 CHLOROPHENYL)SULFONYL]PHENYL] 2 HYDROXYBENZAMIDE; APOPTOSIS INHIBITOR; CYTOCHROME C; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME RELEASE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION;

ANALYSIS OF VARIANCE; BENZAMIDES; BIOMIMETIC MATERIALS; CELL LINE; CELLS, CULTURED; CYTOCHROME C GROUP; FLOW CYTOMETRY; HUMANS; INTRACELLULAR MEMBRANES; MITOCHONDRIA; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS;

EID: 0038217076     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04268.x     Document Type: Article

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