Depletion of Bcl-2 by an antisense oligonucleotide induces apoptosis accompanied by oxidation and externalization of phosphatidylserine in NCI-H226 lung carcinoma cells

Molecular and Cellular Biochemistry

Volumn 234-235, Issue , 2002, Pages 125-133

  Koty, Patrick P ^a   Tyurina, Yulia Y ^a,b   Tyurin, Vladimir A ^b   Liu, Shang Xi ^a   Kagan, Valerian E ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Antisense; Apoptosis; Bcl 2; Externalization; Oxidation; Phosphatidylserine

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FATTY ACID; OXIDIZING AGENT; PARINARIC ACID; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROTEIN BCL 2; RNA; SCAVENGER RECEPTOR; DNA FRAGMENT;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL LABELING; CELL MEMBRANE; CELL SUBPOPULATION; CONTROLLED STUDY; EXPOSURE; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIPID PEROXIDATION; LUNG CARCINOMA; MACROPHAGE; OXIDATION; PHAGOCYTOSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; RNA TRANSLATION; SIGNAL TRANSDUCTION; CELL CULTURE; DRUG EFFECT; GENETICS; LUNG; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; THIN LAYER CHROMATOGRAPHY;

APOPTOSIS; CHROMATOGRAPHY, THIN LAYER; DNA FRAGMENTATION; HUMAN; LIPID PEROXIDATION; LUNG; OLIGONUCLEOTIDES, ANTISENSE; OXIDATION-REDUCTION; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; PROTO-ONCOGENE PROTEINS C-BCL-2; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED; HUMANS;

EID: 4243735676     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015932615769     Document Type: Article

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