Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human β-cells from hyperglycemia-induced apoptosis

Experimental Cell Research

Volumn 303, Issue 1, 2005, Pages 68-78

  Mohanty, S ^a   Spinas, G A ^a   Maedler, K ^a   Zuellig, R A ^a   Lehmann, R ^a   Donath, M Y ^a   Trub T ^b   Niessen, M ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b 8001 Z ^*

Author keywords

Apoptosis; Diabetes; INS 1; Insulin receptor substrate; Proliferation; cell

Indexed keywords

GLUCOSE; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; OLIGONUCLEOTIDE; PALMITIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL ISOLATION; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INNER CELL MASS; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; RAT;

EID: 9644268058     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.09.011     Document Type: Article

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