Fidelity discrimination in DNA polymerase β: Differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair

Journal of the American Chemical Society

Volumn 127, Issue 38, 2005, Pages 13245-13252

  Radhakrishnan, Ravi ^a   Schlick, Tamar ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPUTER SIMULATION; CONFORMATIONS; DNA; IONS; MATHEMATICAL MODELS; REACTION KINETICS;

DNA POLYMERASE; NUCLEOTIDE; REACTION NETWORK MODEL; TEMPLATE JUNCTION;

ENZYMES;

DNA DIRECTED DNA POLYMERASE BETA; PRIMER DNA;

ARTICLE; BASE MISPAIRING; BASE PAIRING; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA DAMAGE; DNA REPAIR; DNA TEMPLATE; ENZYME ACTIVE SITE; EXCISION REPAIR; GENE INSERTION; PHASE TRANSITION; SAMPLING; SIMULATION; X RAY CRYSTALLOGRAPHY;

BASE PAIR MISMATCH; BASE SEQUENCE; COMPUTER SIMULATION; DNA POLYMERASE BETA; MODELS, MOLECULAR; TIME FACTORS;

EID: 25444442374     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja052623o     Document Type: Article

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