Polymerase β simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions Per Se

Journal of Molecular Biology

Volumn 317, Issue 5, 2002, Pages 651-671

  Yang, Linjing ^a   Beard, William A ^b   Wilson, Samuel H ^b   Broyde, Suse ^a   Schlick, Tamar ^a  

^a NEW YORK UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Closed state; Dynamics simulations; Fidelity; Human DNA polymerase ; Open state

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; NUCLEOTIDE; WATER;

ARTICLE; BASE PAIRING; CATALYSIS; CRYSTAL STRUCTURE; DENSITY; DNA REPAIR; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; ROTATION; SIMULATION;

MAMMALIA;

EID: 0036295231     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2002.5450     Document Type: Article

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