Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase β

Journal of Biological Chemistry

Volumn 271, Issue 21, 1996, Pages 12141-12144

  Beard, William A ^a   Osheroff, Wendy P ^b   Prasad, Rajendra ^a   Sawaya, Michael R ^c   Jaju, Madhuri ^a   Wood, Thomas G ^a   Kraut, Joseph ^c   Kunkel, Thomas A ^b   Wilson, Samuel H ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DIRECTED DNA POLYMERASE BETA;

AMINO ACID SUBSTITUTION; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; DNA; DNA POLYMERASE I; ESCHERICHIA COLI; HUMANS; HYDROGEN BONDING; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEOTIDES;

EID: 17544370107     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.21.12141     Document Type: Article

References (30)

1. Wiebauer, K., and Jiricny, J. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 5842-5845
2. Dianov, G., and Lindahl, T. (1994) Curr. Biol. 4, 1069-1076
3. Horton, J. K., Srivastava, D. K., Zmudzka, B. Z., and Wilson, S. H. (1995) Nucleic Acids Res. 23, 3810-3815
4. Singhal, R. K., Prasad, R., and Wilson, S. H. (1995) J. Biol. Chem. 270, 949-957
5. Sobol, R. W., Horton, J. K., Kühn, R., Gu, H., Singhal, R. K., Prasad, R., Rajewsky, K., and Wilson, S. H. (1996) Nature 379, 183-186
6. Linn, S. (1991) Cell 66, 185-187
7. Jenkins, T. M., Saxena, J. K., Kumar, A., Wilson, S. H., and Ackerman, E. J. (1992) Science 258, 475-478
8. Sweasy, J. B., and Loeb, L. A. (1992) J. Biol. Chem. 267, 1407-1410
9. Sawaya, M. R., Pelletier, H., Kumar, A., Wilson, S. H., and Kraut, J. (1994) Science 264, 1930-1935
10. Pelletier, H., Sawaya, M. R., Kumar, A., Wilson, S. H., and Kraut, J. (1994) Science 264, 1891-1903
11. Pelletier, H., Sawaya, M. R., Wolfle, W., Wilson, S. H., and Kraut, J. (1996) Biochemistry, in press
12. Pelletier, H., Sawaya, M. R., Wolfle, W., Wilson, S. H., and Kraut, J. (1996) Biochemistry, in press
13. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., and Steitz, T. A. (1992) Science 256, 1783-1790
14. Seeman, N. C., Rosenberg, J. M., and Rich, A. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 804-808
15. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
16. Beard, W. A., and Wilson, S. H. (1995) Methods Enzymol. 262, 98-107
17. Roberts, J. D., Bebenek, K., and Kunkel, T. A. (1988) Science 242, 1171-1173
18. Beard, W. A., and Wilson, S. H. (1993) Biochemistry 32, 9745-9753
19. Bebenek, K., and Kunkel, T. A. (1995) Methods Enzymol. 262, 217-232
20. Hamlin, R. (1985) Methods Enzymol. 114, 416-452
21. Singhal, R. K., and Wilson, S. H. (1993) J. Biol. Chem. 268, 15906-15911
22. Kunkel, T. A. (1985) J. Biol. Chem. 260, 5787-5796
23. Kunkel, T. A., and Soni, A. (1988) J. Biol. Chem. 263, 14784-14789
24. Feig, D. I., and Loeb, L. A. (1993) Biochemistry 32, 4466-4473
25. Feig, D. I., and Loeb, L. A. (1994) J. Mol. Biol. 235, 33-41
26. Prasad, R., Beard, W. A., and Wilson, S. H. (1994) J. Biol. Chem. 269, 18096-18101
27. Joyce, C. M., and Steitz, T. A. (1995) J. Bacteriol. 177, 6321-6329
28. Kennard, O. (1988) in Structure and Expression, DNA and Its Drug Complexes (Sarma, R. H., and Sarma, M. H., eds) Vol. 2, pp. 1-25, Adenine Press, Guilderland, NY
29. Echols, H., and Goodman, M. F. (1991) Annu. Rev. Biochem. 60, 477-511
30. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950