Effects of RNAi-mediated silencing of PEN-2, APH-1a, and nicastrin on wild-type vs FAD mutant forms of presenilin

Journal of Molecular Neuroscience

Volumn 25, Issue 1, 2005, Pages 67-77

  Xie, Zhongcong ^a   Romano, Donna M ^a   Tanzi, Rudolph E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

secretase; Alzheimer's disease; Mutation; PEN 2; Presenilin 1; RNA interference

Indexed keywords

FLAVINE ADENINE NUCLEOTIDE; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2; PROTEIN; PROTEIN APH 1A; PROTEIN PEN 2; UNCLASSIFIED DRUG; APH1A PROTEIN, HUMAN; MEMBRANE PROTEIN; NICASTRIN PROTEIN; PEPTIDE HYDROLASE; PSEN1 PROTEIN, HUMAN; PSENEN PROTEIN, HUMAN; SECRETASE; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; EXON; GENE MUTATION; GENETIC TRANSFECTION; GLIOMA; HUMAN; HUMAN CELL; MISSENSE MUTATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA INTERFERENCE; WILD TYPE; GENE SILENCING; GENETICS; METABOLISM; MUTATION; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE, TUMOR; GENE SILENCING; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MUTATION; PEPTIDE HYDROLASES; PRESENILIN-1; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 25144489700     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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