Amyloid precursor protein metabolism in fibroblasts from individuals with one, two or three copies of the amyloid precursor protein (APP) gene

Biochemical Journal

Volumn 338, Issue 3, 1999, Pages 777-782

  Racchi, Marco ^a,c   Johnston, Janet A ^b,d   Flood, Fiona M ^b   Cowburn, Richard F ^b   Govoni, Stefano ^a,c  

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF PAVIA   (Italy)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

secretase; amyloid; Alzheimer's disease; Chromosome 21; Down's syndrome; Protein kinase C

Indexed keywords

AMYLOID PRECURSOR PROTEIN; MESSENGER RNA; PHORBOL ESTER; PROTEIN KINASE C;

ARTICLE; CHROMOSOME 21; CONTROLLED STUDY; DOSE RESPONSE; DOWN SYNDROME; ENZYME ACTIVITY; GENE DELETION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SECRETION; SKIN FIBROBLAST; TRISOMY 21;

ADULT; AMYLOID BETA-PROTEIN PRECURSOR; DOWN SYNDROME; ENZYME ACTIVATION; FIBROBLASTS; GENE DOSAGE; HUMANS; MIDDLE AGED; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RNA, MESSENGER;

EID: 0033559738     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3380777     Document Type: Article

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