Tomato products and lycopene supplements: Mandatory components in nutritional treatment of cancer patients?

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 6, Issue 6, 2003, Pages 657-660

  Müller, Nadine ^a   Alteheld, Birgit ^a   Stehle, Peter ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Cancer; Clinical trials; Experimental studies; Lycopene; Oral enteral supplementation; Tomato products

Indexed keywords

BIOLOGICAL MARKER; LYCOPENE; ANTIOXIDANT; CAROTENOID;

CANCER INHIBITION; CANCER PATIENT; CANCER PREVENTION; CARCINOGENESIS; CLINICAL TRIAL; DIET THERAPY; DIETARY INTAKE; DIGESTIVE SYSTEM CANCER; ENTERIC FEEDING; FOOD INTAKE; HUMAN; LUNG CANCER; NONHUMAN; NUTRITIONAL SUPPORT; PROSTATE CANCER; REVIEW; TOMATO; CASE CONTROL STUDY; DIET SUPPLEMENTATION; FEMALE; MALE; NEOPLASM; STATISTICS;

ANIMALIA; LYCOPERSICON ESCULENTUM;

ANTIOXIDANTS; CAROTENOIDS; CASE-CONTROL STUDIES; CLINICAL TRIALS; DIETARY SUPPLEMENTS; FEMALE; HUMANS; LYCOPERSICON ESCULENTUM; MALE; NEOPLASMS;

EID: 2442507029     PISSN: 13631950     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075197-200311000-00009     Document Type: Review

References (35)

1. World Cancer Research Fund, American Institute for Cancer research. Food, nutrition and the prevention of cancer: a global perspective. Washington, DC: American Institute for Cancer Research; 1997.
2. Giovannucci E, Rimm EB, Liu Y, et al. A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst 2002; 94:391-398. A highly sophisticated statistical analysis of data from the Health Professionals Follow-Up Study.
3. Vogt TM, Mayne ST, Graubard BJ, et al. Serum lycopene, other serum carotinoids, and risk of prostate cancer in US blacks and whites. Am J Epidemiol 2002; 155:1023-1032.
4. Pohar KS, Gong MC, Bahnson R, et al. Tomatoes, lycopene and prostate cancer: a clinician's guide for counselling those at risk for prostate cancer. World J Urol 2003; 21:9-14.
5. Miller EC, Giovannucci E, Erdman JW, et al. Tomato products, lycopene, and prostate cancer risk. Urol Clin North Am 2002; 29:83-93.
6. Ito Y, Wakai K, Suzuki K, et al. Serum carotinoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study. Cancer Sci 2003; 94:57-63. Using an innovative animal model, this study provides new insights into how lycopene alters the cellular biomarkers of carcinogenesis.
7. Terry P, Jain M, Miller AB, et al. Dietary carotinoid intake and colorectal cancer risk. Nutr Cancer 2002; 42:167-172.
8. Michaud DS, Pietinen P, Taylor PR, et al. Intakes of fruits and vegetables, carotinoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study. Br J Cancer 2002; 87:960-965.
9. Okajima E, Tsutsumi M, Ozono S, et al. Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl) nitrosamine initiation. Jpn J Cancer Res 1998; 89:22-26.
10. Kim DJ, Takasuka N, Kim JM, et al. Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH. Cancer Lett 1997; 120:15-22.
11. Kim DJ, Takasuka N, Nishino H, et al. Chemoprevention of lung cancer by lycopene. Biofactors 2000; 13:95-102.
12. Nagasawa H, Mitamura T, Sakamoto S, et al. Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice. Anticancer Res 1995; 15:1173-1178.
13. Cohen LA, Zhao Z, Pittman B, et al. Effect of dietary lycopene on N-methylnitrosourea-induced mammary tumorigenesis. Nutr Cancer 1999; 34:153-159.
14. He Y, Root MM, Parker RS, et al. Effects of carotenoid-rich food extracts on the development of preneoplastic lesions in rat liver and on in vivo and in vitro antioxidant status. Nutr Cancer 1997; 27:238-244.
15. Liu C, Lian F, Smith DE, et al. Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Res 2003; 63:3138-3144.
16. Tzonou A, Signorello LB, Lagiou P, et al. Diet and cancer of the prostate: a case-control study in Greece. Int J Cancer 1999; 80:704-708.
17. Bosetti C, Tzonou A, Lagiou P, et al. Fraction of prostate cancer incidence attributed to diet in Athens, Greece. Eur J Cancer Prev 2000; 9:119-123.
18. Jain MG, Hislop GT, Howe GR, et al. Plant foods, antioxidants, and prostate cancer risk: findings from case-control studies in Canada. Nutr Cancer 1999; 34:173-184.
19. Kolonel LN, Hankin JH, Whittemore AS, et al. Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control study. Cancer Epidemiol Biomarkers Prev 2000; 9:795-804.
20. Mucci LA, Tamimi R, Lagiou P, et al. Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system? BJU Int 2001; 87:814-820.
21. Signorello LB, Kuper H, Lagiou P, et al. Lifestyle factors and insulin-like growth factor 1 levels among elderly men. Eur J Cancer Prev 2000; 9:173-178.
22. Gann PH, Ma J, Giovannucci E, et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 1999; 59:1225-1230.
23. Rao AV, Fleshner N, Agarwal S. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case-control study. Nutr Cancer 1999; 33:159-164.
24. Agudo A, Esteve MG, Pallares C, et al. Vegetable and fruit intake and the risk of lung cancer in women in Barcelona, Spain. Eur J Cancer 1997; 33:1256-1261.
25. Darby S, Whitley E, Doll R, et al. Diet, smoking and lung cancer: a case-control study of 1000 cases and 1500 controls in south-west England. Br J Cancer 2001; 84:728-735.
26. Terry P, Lagergren J, WoIk A, et al. Reflux-inducing dietary factors and risk of adenocarcinoma of the esophagus and gastric cardia. Nutr Cancer 2000; 38:186-191.
27. Gao CM, Takezaki T, Ding JH, et al. Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China. Jpn J Cancer Res 1999; 90:614-321.
28. Fernandez E, La Vecchia C, D'Avanzo B, et al. Risk factors for colorectal cancer in subjects with family history of the disease. Br J Cancer 1997; 75:1381-1384.
29. Morales Suarez-Varela M, Jimenez Lopez MC, Almenar Cubells D, et al. Effect of the ingestion of food and gynecologic risk factors on breast cancer risk in Valencia. Nutr Hosp 1998; 13:325-329.
30. De Stefani E, Boffetta P, Oreggia F, et al. Plant foods and risk of laryngeal cancer: a case-control study in Uruguay. Int J Cancer 2000; 87:129-132.
31. Rao AV, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutr Cancer 1998; 31:199-203.
32. Pool-Zobel BL, Bub A, Muller H, et al. Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Carcinogenesis 1997; 18:1847-1850.
33. Van Breemen RB, Xu X, Viana MA, et al. Liquid chromatography-mass spectrometry of cis- and all-trans-lycopene in human serum and prostate tissue after dietary supplementation with tomato sauce. J Agric Food Chem 2002; 20:2214-2219. An interesting new methodological approach with the goal of controlling the effect of tissue targeting by dietary supplementation.
34. Kucuk O, Sarkar FH, Djuric Z, et al. Effects of lycopene supplementation in patients with localized prostate cancer. Exp Biol Med 2002; 227:881-885. One of the first intervention trials in cancer patients.
35. Bowen P, Chen L, Stacewicz-Sapuntzakis M, et al. Tomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis. Exp Biol Med 2002; 227:886-893. One of the first intervention trials in cancer patients.