Effect of dietary lycopene on N-methylnitrosourea-induced mammary tumorigenesis

Nutrition and Cancer

Volumn 34, Issue 2, 1999, Pages 153-159

  Cohen, Leonard A ^a   Zhao, Zhonglin ^a   Pittman, Brian ^a   Khachik, Frederick ^b  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAROTENOID; LYCOPENE; METHYLNITROSOUREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; CANCER INCIDENCE; CANCER INHIBITION; CANCER LOCALIZATION; CANCER RISK; CANCER SIZE; CONTROLLED STUDY; FEMALE; LATENT PERIOD; NONHUMAN; RAT; WEIGHT GAIN;

ANIMALIA; LYCOPERSICON ESCULENTUM;

EID: 0032759995     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC3402_5     Document Type: Article

References (61)

1. Vaino, H, and Rautalehti, M: An international evaluation of the cancer preventive potential of carotenoids. Cancer Epidermal Biomarkers Prev 7, 725-728, 1998.
2. Block, G, Patterson, B, and Subar A: Fruit, vegetables, and cancer prevention: a review of epidemiological evidence. Nutr Cancer 18, 1-29, 1992.
3. Gerster, H: Review: anticarcinogenic effects of common carotenoids. Int J Vitam Nutr Res 63, 93-121, 1993.
4. ATBC Cancer Prevention Study Group: The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330, 1029-1035, 1994.
5. Greenberg, ER, Baron, JA, Toteson, TD, Freeman, DH, Beck, GJ, et al.: Clinical trial of antioxidant vitamins to prevent colorectal adenocarcinoma. N Engl J Med 331, 141-147, 1994.
6. Krinsky, NI: Overview of lycopene, carotenoids, and disease prevention. Proc Soc Exp Biol Med 218, 95-100, 1998.
7. Khachik, F, Beecher, GR, and Smith, JC: Lutein, lycopene, and their oxidative metabolites in chemoprevention of cancer. J Cell Biochem 22, 236-246, 1995.
8. Stahl, W, and Sies, H: Lycopene: a biologically important carotenoid for humans? Arch Biochem Biophys 336, 1-9, 1996.
9. Khachik, F, Spangler, CJ, Smith, JC, Canfield, LM, Steck, A, et al.: Identification, quantification and relative concentrations of carotenoids and their metabolites in human milk and serum. Anal Chem 69, 1873-1881, 1997.
10. Kanetsky, PA, Gammon, MD, Mandelblatt, J, Zhang, Z-F, Ramsey, E, et al.: Dietary intake and blood levels of lycopene: association with cervical dysplasia among non-Hispanic black women. Nutr Cancer 31, 31-40, 1998.
11. Potischman, N, Hoover, RN, Brinton, LA, Swanson, CA, Herroro, R, et al.: The relations between cervical cancer and serological markers of nutritional status. Nutr Cancer 21, 193-201, 1994.
12. Giles, G, and Ireland, P: Diet, nutrition, and prostate cancer. Int J Cancer 10, 13-17, 1997.
13. Giovannucci, E, Ascherio, A, Rimm, EB, Stampfer, MJ, Colditz, GA, et al.: Intake of carotenoids and retinol in relation to risk of prostate cancer. JNCI 87, 1767-1776, 1995.
14. Franceschi, S, Bidoli, E, La Vecchia, C, Talamini, R, D'Avanzo, B, et al.: Tomatoes and risk of digestive-tract cancers. Int J Cancer 59, 181-184, 1994.
15. Batieha, AM, Armenian, HK, Nerkus, EP, Morris, JS, Spate, VE, et al.: Serum micronutrients and subsequent risk of cervical cancer in a population-based nested case-control study. Cancer Epidemiol Biomarkers Prev 2, 335-339, 1993.
16. Giovannucci, EL, Ascherio, A, Rimm, EB, Stampfer, MJ, Colditz, GA, et al.: Intake of carotenoids and retinol in relationship to risk of prostate cancer. JNCI 87, 1767-1776, 1995.
17. Snowdon, D: Antioxidants and reduced functional capacity in the elderly: findings from the Nun Study. J Gerontol 51A, M10-M16, 1996.
18. Burney, PGJ, Comstock, GW, and Morris, JS: Serologic precursors of cancer: serum micronutrients and subsequent risk of pancreatic cancer. Am J Clin Nutr 49, 895-900, 1989.
19. Helzlsouer, KJ, Comstock, GW, and Morris, JS: Selenium, lycopene, α-tocopherol, β-carotene, retinol, and subsequent bladder cancer. Cancer Res 49, 6144-6148, 1989.
20. VanEenwyk, J, Davis, FG, and Bowen, PE: Dietary and serum carotenoids and cervical intraepithelial neoplasia. Int J Cancer 48, 34-38, 1991.
21. Kvale, G, Bjelke, E, and Gart, JJ: Dietary habits and lung cancer risk. Int J Cancer 31, 397-405, 1983.
22. Hsing, AW, Comstock, GW, Abbey, H, and Polk, BF: Serological precursors of cancer. Retinol, carotenoids, and tocopherol and risk of prostate cancer. JNCI 82, 941-946, 1990.
23. Kim, DJ, Takasuka, N, Kim, JM, Sekine, K, Ota, K, et al.: Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEM, MNU and DMH. Cancer Lett 120, 15-22, 1997.
24. Okajima, E, Ozono, S, Endo, T, Majima, T, Tsutsumi, M, et al.: Chemopreventive efficacy of piroxicam administered alone or in combination with lycopene and β-carotene on the development of rat urinary bladder carcinoma after N-butyl-N-(4-hydroxybutyl)nitrosamine treatment. Jpn J Cancer Res 88, 543-552, 1997.
25. Okajima, E, Tsutsumi, M, Ozono, S, Akai, H, Denda, A, et al.: Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation. Jpn J Cancer Res 89, 22-26, 1998.
26. Narisawa, T, Fukaura, Y, Hasebe, M, Nomura, S, Oshima, S, et al.: Prevention of N-methylnitrosourea-induced colon carcinogenesis in F-344 rats by lycopene and tomato juice rich in lycopene. Jpn J Cancer Res 89, 1003-1008, 1998.
27. Narisawa, T, Fukaura, Y, Hasebe, M, Ito, M, Aizawa, R, et al.: Inhibitory effects of natural carotenoids, α-carotene, β-carotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats. Cancer Lett 107, 137-142, 1996.
28. Astorg, P, Gradelet, S, Berges, R, and Suschetet, M: Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat. Nutr Cancer 29, 60-68, 1997.
29. Sharoni, Y, Giron, E, Rise, M, and Levy, J: Effects of lycopene-enriched tomato oleoresin on 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors. Cancer Detect Prev 21, 118-123, 1997.
30. Stahl, W, Nicolai, S, Briviba, K, Hanusch, M, Broszeit, G, et al.: Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching. Carcinogenesis 18, 89-92, 1997.
31. Fukuzawa, K, Inokami, Y, Tokumura, A, Terao, J, and Suzuki, A: Rate constants for quenching singlet oxygen and activities for inhibiting lipid peroxidation of carotenoids and α-tocopherol in liposomes. Lipids 33, 751-756, 1998.
32. Agarwal, S, and Rao, AV: Tomato lycopene and low-density lipoprotein oxidation: a human dietary intervention study. Lipids 33, 981-984, 1998.
33. Zhang, L-X, Conney, RV, and Bertram, JS: Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C34/ 10T1/2 cells: relationship to their chemopreventive action. Carcinogenesis 12, 2109-2114, 1991.
34. Zhang, LX, Cooney, RV, and Bertram, JS: Carotenoids up-regulate connexin 43 gene expression independent of their pro-vitamin A or anti-oxidant properties. Cancer Res 52, 5707-5712, 1992.
35. Weisburger, JH, Dolan, L, and Pittman, B: Inhibition of PhIP mutagenicity by caffeine, lycopene, daidzein, and genistein. Mutat Res 416, 125-128, 1998.
36. Levy, J, Bosin, E, Feldman, B, Giat, Y, Miinster, A, et al.: Lycopene is a more potent inhibitor of human cancer cell proliferation than either α-carotene or β-carotene. Nutr Cancer 24, 257-266, 1995.
37. Nagasawa, H, Mitamura, T, Sakamoto, S, and Yamamoto, K: Effects of lycopene on spontaneous mammary tumor development in SHN virgin mice. Anticancer Res 15, 1173-1178, 1995.
38. Khachik, F, Nir, Z, Ausich, RI, Steck, A, and Pfander, H: Distribution of Carotenoids in fruits and vegetables as a criterion for the selection of appropriate chemopreventive agents. In Food Factors for Cancer Prevention, H Ohigashi, T Osawa, J Terao, S Watanabe, and T Yoshikawa (eds). Tokyo: Springer-Verlag, 1997, pp 204-208.
39. Zhao, Z, Khachik, F, Richie, JP, Jr, and Cohen, LA: Lycopene uptake and tissue disposition in male and female rats. Proc Soc Exp Biol Med 218, 109-114, 1998.
40. Chan, PC, Head, JF, Cohen, IA, and Wynder, EL: Influence of dietary fat on the induction of mammary tumors by N-nitrosomethylurea: associated hormone changes and differences between Sprague-Dawley and F344 rats. JNCI 59, 1279-1283, 1997.
41. Young, S, and Hallowes, RC: Tumors of the mammary gland. In Pathology of Tumors in Laboratory Animals, VS Turosov (ed). Lyon, France: Int Agency Res Cancer, 1973, vol 1, pp 31-74.
42. Russo, J, Russo, JH, Rogers, AE, Van Zwietan, MJ, and Gusterson, B: Tumours of the Mammary Gland. Lyon, France: Int Agency Res Cancer, 1990, pp 47-78. (IARC Sci Publ 99)
43. Kaplan, EL, and Meier, P: Nonparametric estimation from incomplete observation. J Am Stat Assoc 53, 457-481, 1978.
44. Peto, R, and Peto, J: A symptomatically efficient rank invariant procedure. J R Stat Soc 135A, 185-207, 1972.
45. Helwig, JT, and Council, KA (eds). Statistical Analysis User's Guide: Statistics Version, 5th ed. Raleigh, NC: SAS Institute, 1985.
46. Armitage, P: The chi-square test for heterogeneity of proportions after adjustment for stratification. J R Stat Soc 28B, 150-163, 1966.
47. Fleiss, JL: Statistical Methods for Rates and Proportions, 2nd ed. New York: Wiley, 1981, pp 145-146.
48. Mantel, N, and Haenszel, W: Statistical aspects of the analysis of data from retrospective studies of disease. JNCI 22, 719-748, 1959.
49. SAS Institute: SAS for Linear Models: A Guide to the ANOVA and GLM Procedures. Raleigh, NC: SAS Institute, 1981.
50. Fleiss, JL: The Design and Analysis of Clinical Experiments. New York: Wiley, 1986, pp 220-240.
51. Williams, AW, Boileau, TWM, and Erdman, JW, Jr: Factors influencing the uptake and absorption of carotenoids. Proc Soc Exp Biol Med 216, 106-108, 1998.
52. Rich, GT, Fillery-Travis, A, and Parker, ML: Low pH enhances the transfer of carotene from carrot juice to olive oil. Lipids 33, 985-992, 1998.
53. Gartner, C, Stahl, W, and Sies, H: Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr 66, 116-122, 1997.
54. Clark, RM, Yao, L, She, L, and Furr, HC: A comparison of lycopene and canthaxanthin absorption: using the rat to study the absorption of non-provitamin A carotenoids. Lipids 33, 159-163, 1998.
55. Giovannucci, E, and Clinton, SK: Tomatoes, lycopene, and prostate cancer. Proc Soc Exp Biol Med 218, 129-139, 1998.
56. Grann, PH, Ma, J, Giovannucci, E, Willett, W, Sacks, F, et al.: Lower prostate cancer risk in men with elevated lycopene levels: results of a prospective analysis. Cancer Res 59, 1225-1230, 1999.
57. LaVecchia, C: Mediterranean epidemiological evidence on tomatoes and the prevention of digestive-tract cancers. Proc Soc Exp Biol Med 218, 125-128, 1998.
58. Freudenheim, JL, Marshall, JR, Vena, JE, Laughlin, R, Brasure, JR, et al.: Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients. JNCI 88, 340-348, 1996.
59. Jarvinen, R, Knekt, P, Seppanen, R, and Teppo, L: Diet and breast cancer risk in a cohort of Finnish women. Cancer Lett 114, 21-23, 1997.
60. Potischman, N, McCulloch, CE, Byers, T, Nemoto, T, Stubbe, N, et al.: Breast cancer and dietary and plasma concentrations of carotenoids and vitamin A. Am J Clin Nutr 52, 909-915, 1990.
61. Zhang, S, Hunter, DJ, Forman, MR, Rosner, BA, Speizer, FE, et al.: Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. JNCI 91, 547-556, 1999.