메뉴 건너뛰기




Volumn 25, Issue 18, 2005, Pages 8064-8073

A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; SINGLE STRANDED DNA; STN1 PROTEIN; UNCLASSIFIED DRUG;

EID: 24344480452     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.18.8064-8073.2005     Document Type: Article
Times cited : (32)

References (72)
  • 1
    • 0035844082 scopus 로고    scopus 로고
    • Pot1, the putative telomere end-binding protein in fission yeast and humans
    • Baumann, P., and T. R. Cech. 2001. Pot1, the putative telomere end-binding protein in fission yeast and humans. Science 292:1171-1175.
    • (2001) Science , vol.292 , pp. 1171-1175
    • Baumann, P.1    Cech, T.R.2
  • 2
    • 1542781659 scopus 로고    scopus 로고
    • When cells get stressed: An integrative view of cellular senescence
    • Ben-Poratb, I., and R. A. Weinberg. 2004. When cells get stressed: an integrative view of cellular senescence. J. Clin. Investig. 113:8-13.
    • (2004) J. Clin. Investig. , vol.113 , pp. 8-13
    • Ben-Poratb, I.1    Weinberg, R.A.2
  • 3
    • 0022506983 scopus 로고
    • Identification of a telomere-binding activity from yeast
    • Berman, J., C. Y. Tachibana, and B. K. Tye. 1986. Identification of a telomere-binding activity from yeast. Proc. Natl. Acad. Sci. USA 83:3713-3717.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3713-3717
    • Berman, J.1    Tachibana, C.Y.2    Tye, B.K.3
  • 4
    • 3242766201 scopus 로고    scopus 로고
    • Carcinogenesis Young Investigator Award. Telomere epigenetics: A higher-order control of telomere length in mammalian cells
    • Blasco, M. A. 2004. Carcinogenesis Young Investigator Award. Telomere epigenetics: a higher-order control of telomere length in mammalian cells. Carcinogenesis. 25:1083-1087.
    • (2004) Carcinogenesis , vol.25 , pp. 1083-1087
    • Blasco, M.A.1
  • 6
    • 0035504409 scopus 로고    scopus 로고
    • Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction
    • Booth, C., E. Griffith, G. Brady, and D. Lydall. 2001. Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction. Nucleic Acids Res. 29:4414-4422.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4414-4422
    • Booth, C.1    Griffith, E.2    Brady, G.3    Lydall, D.4
  • 7
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan, T. M., A. Englezou, L. Dalla-Pozza, M. A. Dunham, and R. R. Reddel. 1997. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 3:1271-1274.
    • (1997) Nat. Med. , vol.3 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 8
    • 0034805913 scopus 로고    scopus 로고
    • Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae
    • Bucholc, M., Y. Park, and A. J. Lustig. 2001. Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae. Mol. Cell. Biol. 21:6559-6573.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6559-6573
    • Bucholc, M.1    Park, Y.2    Lustig, A.J.3
  • 9
  • 10
    • 7644237444 scopus 로고    scopus 로고
    • Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops
    • Cesare, A. J., and J. D. Griffith. 2004. Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops. Mol. Cell. Biol. 24:9948-9957.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9948-9957
    • Cesare, A.J.1    Griffith, J.D.2
  • 11
    • 0035115859 scopus 로고    scopus 로고
    • Cdc13 both positively and negatively regulates telomere replication
    • Chandra, A., T. R. Hughes, C. I. Nugent, and V. Lundblad. 2001. Cdc13 both positively and negatively regulates telomere replication. Genes Dev. 15:404-414.
    • (2001) Genes Dev. , vol.15 , pp. 404-414
    • Chandra, A.1    Hughes, T.R.2    Nugent, C.I.3    Lundblad, V.4
  • 12
    • 0035131699 scopus 로고    scopus 로고
    • Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events
    • Chen, Q., A. Ijpma, and C. W. Greider. 2001. Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol. Cell. Biol. 21:1819-1827.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1819-1827
    • Chen, Q.1    Ijpma, A.2    Greider, C.W.3
  • 14
    • 0036960825 scopus 로고    scopus 로고
    • Formation of extrachromosomal circles from telomeric DNA in Xenopus laevis
    • Cohen, S., and M. Mechali. 2002. Formation of extrachromosomal circles from telomeric DNA in Xenopus laevis. EMBO Rep. 3:1168-1174.
    • (2002) EMBO Rep. , vol.3 , pp. 1168-1174
    • Cohen, S.1    Mechali, M.2
  • 15
    • 0033781559 scopus 로고    scopus 로고
    • Telomere folding is required for the stable maintenance of telomere position effects in yeast
    • de Bruin, D., S. M. Kantrow, R. A. Liberalere, and V. A. Zakian. 2000. Telomere folding is required for the stable maintenance of telomere position effects in yeast. Mol. Cell. Biol. 20:7991-8000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7991-8000
    • Bruin, D.1    Kantrow, S.M.2    Liberalere, R.A.3    Zakian, V.A.4
  • 16
    • 0030460748 scopus 로고    scopus 로고
    • Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase
    • Dionne, I., and R. J. Wellinger. 1996. Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase. Proc. Natl. Acad. Sci. USA 93:13902-13907.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13902-13907
    • Dionne, I.1    Wellinger, R.J.2
  • 17
    • 0036021349 scopus 로고    scopus 로고
    • A quantitative assay for telomere protection in Saccharomyces cerevisiae
    • DuBois, M. L., Z. W. Haimberger, M. W. McIntosh, and D. E. Gottschling. 2002. A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics 161:995-1013.
    • (2002) Genetics , vol.161 , pp. 995-1013
    • Dubois, M.L.1    Haimberger, Z.W.2    McIntosh, M.W.3    Gottschling, D.E.4
  • 19
    • 0033767689 scopus 로고    scopus 로고
    • Positive and negative regulation of telomerase access to the telomere
    • Evans, S. K., and V. Lundblad. 2000. Positive and negative regulation of telomerase access to the telomere. J. Cell Sci. 113:3357-3364.
    • (2000) J. Cell Sci. , vol.113 , pp. 3357-3364
    • Evans, S.K.1    Lundblad, V.2
  • 20
    • 1642523697 scopus 로고    scopus 로고
    • Indecent exposure: When telomeres become uncapped
    • Ferreira, M. G., K. M. Miller, and J. P. Cooper. 2004. Indecent exposure: when telomeres become uncapped. Mol. Cell 13:7-18.
    • (2004) Mol. Cell , vol.13 , pp. 7-18
    • Ferreira, M.G.1    Miller, K.M.2    Cooper, J.P.3
  • 21
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik, B, M. Carson, and L. Hartwell. 1995. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:6128-6138.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 22
    • 0038246291 scopus 로고    scopus 로고
    • The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae
    • Grandin, N, and M. Charbonneau. 2003. The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae. Mol. Cell. Biol. 23:3721-3734.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3721-3734
    • Grandin, N.1    Charbonneau, M.2
  • 23
    • 0033766666 scopus 로고    scopus 로고
    • Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment
    • Grandin, N, C. Damon, and M. Charbonneau. 2000. Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment. Mol. Cell. Biol. 20:8397-8408.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8397-8408
    • Grandin, N.1    Damon, C.2    Charbonneau, M.3
  • 24
    • 0035502994 scopus 로고    scopus 로고
    • Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
    • Grandin, N., C. Damon, and M. Charbonneau. 2001. Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J. 20:6127-6139.
    • (2001) EMBO J. , vol.20 , pp. 6127-6139
    • Grandin, N.1    Damon, C.2    Charbonneau, M.3
  • 25
    • 0035282781 scopus 로고    scopus 로고
    • Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
    • Grandin, N., C. Damon, and M. Charbonneau. 2001. Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J. 20:1173-1183.
    • (2001) EMBO J. , vol.20 , pp. 1173-1183
    • Grandin, N.1    Damon, C.2    Charbonneau, M.3
  • 26
    • 0031029001 scopus 로고    scopus 로고
    • Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
    • Grandin, N., S. I. Reed, and M. Charbonneau. 1997. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 11:512-527.
    • (1997) Genes Dev. , vol.11 , pp. 512-527
    • Grandin, N.1    Reed, S.I.2    Charbonneau, M.3
  • 28
    • 18944387709 scopus 로고    scopus 로고
    • Recombination at long mutant telomeres produces tiny single- And double-stranded telomeric circles
    • Groff-Vindman, C., A. J. Cesare, S. Natarajan, J. D. Griffith, and M. J. McEachern. 2005. Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles. Mol. Cell. Biol. 25:4406-4412.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4406-4412
    • Groff-Vindman, C.1    Cesare, A.J.2    Natarajan, S.3    Griffith, J.D.4    McEachern, M.J.5
  • 29
    • 2442564703 scopus 로고    scopus 로고
    • Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation
    • Grossi, S., A. Puglisi, P. V. Dmitriev, M. Lopes, and D. Shore. 2004. Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Genes Dev. 18:992-1006.
    • (2004) Genes Dev. , vol.18 , pp. 992-1006
    • Grossi, S.1    Puglisi, A.2    Dmitriev, P.V.3    Lopes, M.4    Shore, D.5
  • 30
    • 0037148281 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres in mammalian cells
    • Henson, J. D., A. A. Neumann, T. R. Yeager, and R. R. Reddel. 2002. Alternative lengthening of telomeres in mammalian cells. Oncogene 21:598-610.
    • (2002) Oncogene , vol.21 , pp. 598-610
    • Henson, J.D.1    Neumann, A.A.2    Yeager, T.R.3    Reddel, R.R.4
  • 32
    • 0037341611 scopus 로고    scopus 로고
    • Short telomeres induce a DNA damage response in Saccharomyces cerevisiae
    • 29a.IJpma, A. S., and C. W. Greider. 2003. Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol. Biol. Cell 14:987-1001.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 987-1001
    • Ijpma, A.S.1    Greider, C.W.2
  • 33
    • 0029743764 scopus 로고    scopus 로고
    • Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
    • Krauskopf, A., and E. H. Blackburn. 1996. Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature 383:354-357.
    • (1996) Nature , vol.383 , pp. 354-357
    • Krauskopf, A.1    Blackburn, E.H.2
  • 34
    • 0032514694 scopus 로고    scopus 로고
    • Rap1 protein regulates telomere turnover in yeast
    • Krauskopf, A., and E. H. Blackburn. 1998. Rap1 protein regulates telomere turnover in yeast. Proc. Natl. Acad. Sci. USA 95:12486-12491.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12486-12491
    • Krauskopf, A.1    Blackburn, E.H.2
  • 35
    • 0023669250 scopus 로고
    • Dynamics of telomere length variation in Tetrahymena thermophila
    • Larson, D. D., E. A. Spangler, and E. H. Blackburn. 1987. Dynamics of telomere length variation in Tetrahymena thermophila. Cell 50:477-483.
    • (1987) Cell , vol.50 , pp. 477-483
    • Larson, D.D.1    Spangler, E.A.2    Blackburn, E.H.3
  • 36
    • 0029778954 scopus 로고    scopus 로고
    • A novel mechanism for telomere size control in Saccharomyces cerevisiae
    • Li, B., and A. J. Lustig. 1996. A novel mechanism for telomere size control in Saccharomyces cerevisiae. Genes Dev. 10:1310-1326.
    • (1996) Genes Dev. , vol.10 , pp. 1310-1326
    • Li, B.1    Lustig, A.J.2
  • 37
    • 13844311437 scopus 로고    scopus 로고
    • Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase δ-mediated telomere-telomere recombination in Saccharomyces cerevisiae
    • Lin, C.-Y., H.-H. Chang, K.-J. Wu, S.-F. Tseng, C.-C. Lin, C.-P. Lin, and S.-C. Teng. 2005. Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase δ-mediated telomere-telomere recombination in Saccharomyces cerevisiae. Eukaryot. Cell 4:327-336.
    • (2005) Eukaryot. Cell , vol.4 , pp. 327-336
    • Lin, C.-Y.1    Chang, H.-H.2    Wu, K.-J.3    Tseng, S.-F.4    Lin, C.-C.5    Lin, C.-P.6    Teng, S.-C.7
  • 39
    • 0027266758 scopus 로고
    • An alternative pathway for yeast telomere maintenance rescues est1-senescence
    • Lundblad, V., and E. H. Blackburn. 1993. An alternative pathway for yeast telomere maintenance rescues est1-senescence. Cell 73:347-360.
    • (1993) Cell , vol.73 , pp. 347-360
    • Lundblad, V.1    Blackburn, E.H.2
  • 40
    • 0242354121 scopus 로고    scopus 로고
    • Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion
    • Lustig, A. J. 2003. Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion. Nat. Rev. Genet. 4:916-923.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 916-923
    • Lustig, A.J.1
  • 41
    • 0029746495 scopus 로고    scopus 로고
    • Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
    • McEachern, M. J., and E. H. Blackburn. 1996. Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev. 10:1822-1834.
    • (1996) Genes Dev. , vol.10 , pp. 1822-1834
    • McEachern, M.J.1    Blackburn, E.H.2
  • 42
    • 0029102354 scopus 로고
    • Runaway telomere elongation caused by telomerase RNA gene mutations
    • McEachern, M. J., and E. H. Blackburn. 1995. Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376:403-409.
    • (1995) Nature , vol.376 , pp. 403-409
    • McEachern, M.J.1    Blackburn, E.H.2
  • 43
    • 0035016368 scopus 로고    scopus 로고
    • Short telomeres in yeast are highly recombinogenic
    • McEachern, M. J., and S. Iyer. 2001. Short telomeres in yeast are highly recombinogenic. Mol. Cell 7:695-704.
    • (2001) Mol. Cell , vol.7 , pp. 695-704
    • McEachern, M.J.1    Iyer, S.2
  • 44
    • 0034633692 scopus 로고    scopus 로고
    • Telomere fusions caused by mutating the terminal region of telomeric DNA
    • McEachern, M. J., S. Iyer, T. B. Fulton, and E. H. Blackburn. 2000. Telomere fusions caused by mutating the terminal region of telomeric DNA. Proc. Natl. Acad. Sci. USA 97:11409-11414.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11409-11414
    • McEachern, M.J.1    Iyer, S.2    Fulton, T.B.3    Blackburn, E.H.4
  • 46
    • 0028007237 scopus 로고
    • Telomere dynamics in an immortal human cell line
    • Murnane, J. P., L. Sabatier, B. A. Marder, and W. F. Morgan. 1994. Telomere dynamics in an immortal human cell line. EMBO J. 13:4953-4962.
    • (1994) EMBO J. , vol.13 , pp. 4953-4962
    • Murnane, J.P.1    Sabatier, L.2    Marder, B.A.3    Morgan, W.F.4
  • 47
    • 0033406877 scopus 로고    scopus 로고
    • Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops
    • Murti, K. G., and D. M. Prescott. 1999. Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops. Proc. Natl. Acad. Sci. USA 96:14436-14439.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14436-14439
    • Murti, K.G.1    Prescott, D.M.2
  • 48
    • 0142217320 scopus 로고    scopus 로고
    • Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis
    • Natarajan, S., C. Groff-Vindman, and M. J. McEachern. 2003. Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis. Eukaryot Cell. 2:1115-1127.
    • (2003) Eukaryot Cell. , vol.2 , pp. 1115-1127
    • Natarajan, S.1    Groff-Vindman, C.2    McEachern, M.J.3
  • 49
    • 0036269549 scopus 로고    scopus 로고
    • Recombinational telomere elongation promoted by DNA circles
    • Natarajan, S., and M. J. McEachern. 2002. Recombinational telomere elongation promoted by DNA circles. Mol. Cell. Biol. 22:4512-4521.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4512-4521
    • Natarajan, S.1    McEachern, M.J.2
  • 50
    • 4444274914 scopus 로고    scopus 로고
    • Characterization of Kluyveromyces lactis subtelomeric sequences including a distal element with strong purine/ pyrimidine strand bias
    • Nickles, K., and M. J. McEachern. 2004. Characterization of Kluyveromyces lactis subtelomeric sequences including a distal element with strong purine/ pyrimidine strand bias. Yeast 21:813-830.
    • (2004) Yeast , vol.21 , pp. 813-830
    • Nickles, K.1    McEachern, M.J.2
  • 51
    • 3342974395 scopus 로고    scopus 로고
    • Closed chromatin loops at the ends of chromosomes
    • Nikitina, T, and C. L. Woodcock. 2004. Closed chromatin loops at the ends of chromosomes. J. Cell Biol. 166:161-165.
    • (2004) J. Cell Biol. , vol.166 , pp. 161-165
    • Nikitina, T.1    Woodcock, C.L.2
  • 52
    • 0029845892 scopus 로고    scopus 로고
    • Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
    • Nugent, C. I., T. R. Hughes, N. F. Lue, and V. Lundblad. 1996. Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 274:249-252.
    • (1996) Science , vol.274 , pp. 249-252
    • Nugent, C.I.1    Hughes, T.R.2    Lue, N.F.3    Lundblad, V.4
  • 53
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • Pennock, E., K. Buckley, and V. Lundblad. 2001. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104:387-396.
    • (2001) Cell , vol.104 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 54
    • 0033519630 scopus 로고    scopus 로고
    • Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids
    • Perrem, K., T. M. Bryan, A. Englezou, T. Hackl, E. L. Moy, and R. R. Reddel. 1999. Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids. Oncogene 18:3383-3390.
    • (1999) Oncogene , vol.18 , pp. 3383-3390
    • Perrem, K.1    Bryan, T.M.2    Englezou, A.3    Hackl, T.4    Moy, E.L.5    Reddel, R.R.6
  • 55
    • 0034998040 scopus 로고    scopus 로고
    • Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells
    • Perrem, K., L. M. Colgin, A. A. Neumann, T. R. Yeager, and R. R. Reddel. 2001. Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells. Mol. Cell. Biol. 21:3862-3875.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3862-3875
    • Perrem, K.1    Colgin, L.M.2    Neumann, A.A.3    Yeager, T.R.4    Reddel, R.R.5
  • 56
    • 0034661246 scopus 로고    scopus 로고
    • The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein
    • Qi, H., and V. A. Zakian. 2000. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein. Genes Dev. 14:1777-1788.
    • (2000) Genes Dev. , vol.14 , pp. 1777-1788
    • Qi, H.1    Zakian, V.A.2
  • 57
    • 0031262792 scopus 로고    scopus 로고
    • Immortalized cells with no detectable telomerase activity. A review
    • Reddel, R. R., T. M. Bryan, and J. P. Murnane. 1997. Immortalized cells with no detectable telomerase activity. A review. Biochemistry (Moscow) 62:1254-1262.
    • (1997) Biochemistry (Moscow) , vol.62 , pp. 1254-1262
    • Reddel, R.R.1    Bryan, T.M.2    Murnane, J.P.3
  • 59
    • 0345643517 scopus 로고    scopus 로고
    • Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast
    • Smith, C. D., and E. H. Blackburn. 1999. Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast. J. Cell Biol. 145:203-214.
    • (1999) J. Cell Biol. , vol.145 , pp. 203-214
    • Smith, C.D.1    Blackburn, E.H.2
  • 60
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska, A., and T. de Lange. 2004. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73:177-208.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 61
    • 0037178740 scopus 로고    scopus 로고
    • Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
    • Sogo, J. M., M. Lopes, and M. Foiani. 2002. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297:599-602.
    • (2002) Science , vol.297 , pp. 599-602
    • Sogo, J.M.1    Lopes, M.2    Foiani, M.3
  • 62
    • 0033513079 scopus 로고    scopus 로고
    • Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
    • Teng, S. C., and V. A. Zakian. 1999. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:8083-8093.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8083-8093
    • Teng, S.C.1    Zakian, V.A.2
  • 63
    • 0034669495 scopus 로고    scopus 로고
    • Extragenomic double-stranded DNA circles in yeast with linear mitochondrial genomes: Potential involvement in telomere maintenance
    • Tomaska, L., J. Nosek, A. M. Makhov, A. Pastorakova, and J. D. Griffith. 2000. Extragenomic double-stranded DNA circles in yeast with linear mitochondrial genomes: potential involvement in telomere maintenance. Nucleic Acids Res. 28:4479-4487.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4479-4487
    • Tomaska, L.1    Nosek, J.2    Makhov, A.M.3    Pastorakova, A.4    Griffith, J.D.5
  • 64
    • 10944271790 scopus 로고    scopus 로고
    • Taz1 binding to a fission yeast model telomere: Formation of telomeric loops and higher order structures
    • Tomaska, L., S. Willcox, J. Slezakova, J. Nosek, and J. D. Griffith. 2004. Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures. J. Biol. Chem. 279:50764-50772.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50764-50772
    • Tomaska, L.1    Willcox, S.2    Slezakova, J.3    Nosek, J.4    Griffith, J.D.5
  • 65
    • 14744276374 scopus 로고    scopus 로고
    • Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis
    • Topcu, Z., K. Nickles, C. Davis, and M. J. McEachern. 2005. Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis. Proc. Natl. Acad. Sci. USA 102:3348-3353.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 3348-3353
    • Topcu, Z.1    Nickles, K.2    Davis, C.3    McEachern, M.J.4
  • 66
    • 2542450605 scopus 로고    scopus 로고
    • Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres
    • Underwood, D. H., C. Carroll, and M. J. McEachern. 2004. Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres. Eukaryot Cell. 3:369-384.
    • (2004) Eukaryot Cell. , vol.3 , pp. 369-384
    • Underwood, D.H.1    Carroll, C.2    McEachern, M.J.3
  • 68
    • 0025020278 scopus 로고
    • Intermediates of recombination during mating type switching in Saccharomyces cerevisiae
    • White, C. I., and J. E. Haber. 1990. Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J. 9:663-673.
    • (1990) EMBO J. , vol.9 , pp. 663-673
    • White, C.I.1    Haber, J.E.2
  • 69
    • 0023131381 scopus 로고
    • Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: Structural and functional relationships to GAL4 of Saccharomyces cerevisiae
    • Wray, L. V., Jr., M. M. Witte, R. C. Dickson, and M. I. Riley. 1987. Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiae. Mol. Cell Biol. 7:1111-1121.
    • (1987) Mol. Cell Biol. , vol.7 , pp. 1111-1121
    • Wray Jr., L.V.1    Witte, M.M.2    Dickson, R.C.3    Riley, M.I.4
  • 71
    • 3142679378 scopus 로고    scopus 로고
    • POT1-interacting protein PIP1: A telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
    • Ye, J. Z., D. Hockemeyer, A. N. Krutchinsky, D. Loayza, S. M. Hooper, B. T. Chait, and T. de Lange. 2004. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev. 18:1649-1654.
    • (2004) Genes Dev. , vol.18 , pp. 1649-1654
    • Ye, J.Z.1    Hockemeyer, D.2    Krutchinsky, A.N.3    Loayza, D.4    Hooper, S.M.5    Chait, B.T.6    De Lange, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.