Structural determinants of benzodiazepine allosteric regulation of GABAA receptor currents

Journal of Neuroscience

Volumn 25, Issue 35, 2005, Pages 8056-8065

  Jones Davis, Dorothy M ^a   Song, Luyan ^b   Gallagher, Martin J ^b   Macdonald, Robert L ^b,c,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Benzodiazepines; Binding gating transduction; Coupling; GABAA receptors; Ion channel structure function; Receptor chimera

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; FLUNITRAZEPAM; FLURAZEPAM; PENICILLIN G; RECEPTOR SUBUNIT; STREPTOMYCIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; CHIMERA; CONTROLLED STUDY; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; BENZODIAZEPINES; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RATS; RECEPTORS, GABA-A; SIGNAL TRANSDUCTION;

EID: 24344457069     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0348-05.2005     Document Type: Article

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