Two tyrosine residues on the α subunit are crucial for benzodiazepine binding and allosteric modulation of γ-aminobutyric acid(A) receptors

Molecular Pharmacology

Volumn 51, Issue 5, 1997, Pages 833-841

  Amin, Jahanshah ^a   Brooks Kayal, Amy ^b   Weiss, David S ^c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BENZODIAZEPINE DERIVATIVE; CHLORIDE CHANNEL; DIAZEPAM; PROTEIN SUBUNIT; TYROSINE;

ARTICLE; BINDING SITE; DRUG BINDING; DRUG MECHANISM; EMBRYO CELL; HUMAN; HUMAN CELL; KIDNEY CELL; LIGAND BINDING; MUTATION; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; VOLTAGE CLAMP;

EID: 0030960354     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.5.833     Document Type: Article

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