C-Terminal Domain of the Membrane Copper Transporter Ctr1 from Saccharomyces cerevisiae Binds Four Cu(I) Ions as a Cuprous-Thiolate Polynuclear Cluster: Sub-femtomolar Cu(I) Affinity of Three Proteins Involved in Copper Trafficking

Journal of the American Chemical Society

Volumn 126, Issue 10, 2004, Pages 3081-3090

  Xiao, Zhiguang ^a   Loughlin, Fionna ^a   George, Graham N ^b   Howlett, Geoffrey J ^a   Wedd, Anthony G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; IONIZATION; MASS SPECTROMETRY; METABOLISM; PROTEINS; TRANSPORT PROPERTIES; ULTRAVIOLET SPECTROSCOPY;

COPPER TRAFFICKING; EQUILIBRIUM CONSTANTS;

COPPER;

BATHOCUPROINE DISULFONATE; CHAPERONE; FUNGAL PROTEIN; PROTEIN ATX1; PROTEIN CTR1; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ARTICLE; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; CYTOSOL; DISSOCIATION CONSTANT; ELECTROSPRAY MASS SPECTROMETRY; EQUILIBRIUM CONSTANT; METABOLISM; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

AMINO ACID SEQUENCE; CATION TRANSPORT PROTEINS; CATIONS, MONOVALENT; CIRCULAR DICHROISM; COPPER; ESCHERICHIA COLI; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, X-RAY EMISSION; SULFHYDRYL COMPOUNDS;

EID: 1642404510     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0390350     Document Type: Article

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