-
3
-
-
0034234028
-
Advances in enzymatic transformation of penicillins to 6-aminopenicillanic acid (6-APA)
-
Parmar A, Kumar H, Marwaha S, Kennedy J. Advances in enzymatic transformation of penicillins to 6-aminopenicillanic acid (6-APA). Biotechnol Adv 2000;18:289-301.
-
(2000)
Biotechnol Adv
, vol.18
, pp. 289-301
-
-
Parmar, A.1
Kumar, H.2
Marwaha, S.3
Kennedy, J.4
-
4
-
-
0037506386
-
Evaluation of different enzymes as catalysts for the production of β-lactam antibiotics following a kinetically controlled strategy
-
Hernández-Jústiz O, Terreni M, Pagani G, García J, Guisán J, Fernández-Lafuente R. Evaluation of different enzymes as catalysts for the production of β-lactam antibiotics following a kinetically controlled strategy. Enzyme Microb Technol 1999;25:336-43.
-
(1999)
Enzyme Microb Technol
, vol.25
, pp. 336-343
-
-
Hernández-Jústiz, O.1
Terreni, M.2
Pagani, G.3
García, J.4
Guisán, J.5
Fernández-Lafuente, R.6
-
5
-
-
0036183409
-
Kinetic and thermodynamic approach to design of processes for enzymatic synthesis of betalactams
-
Kurochkina V, Nys P. Kinetic and thermodynamic approach to design of processes for enzymatic synthesis of betalactams. Biocatal Biotransform 2002;20:35-41.
-
(2002)
Biocatal Biotransform
, vol.20
, pp. 35-41
-
-
Kurochkina, V.1
Nys, P.2
-
6
-
-
0035903842
-
Modulation of penicillin acylase properties via immobilization techniques: One-pot chemoenzymatic synthesis of cephamandole from cephalosporin C
-
Terreni M, Pagani G, Ubiali D, Fernández-Lafuente R, Mateo C, Guisán J. Modulation of penicillin acylase properties via immobilization techniques: one-pot chemoenzymatic synthesis of cephamandole from cephalosporin C. Bioorg Med Chem Lett 2001;11:2429-32.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 2429-2432
-
-
Terreni, M.1
Pagani, G.2
Ubiali, D.3
Fernández-Lafuente, R.4
Mateo, C.5
Guisán, J.6
-
7
-
-
0034682159
-
Cross-linked aggregates: A simple and effective method for the immobilization of penicillin acylase
-
Cao L, van Rantwijk F, Sheldon R. Cross-linked aggregates: a simple and effective method for the immobilization of penicillin acylase. Org Lett 2000;2:1361-4.
-
(2000)
Org Lett
, vol.2
, pp. 1361-1364
-
-
Cao, L.1
Van Rantwijk, F.2
Sheldon, R.3
-
8
-
-
0035931490
-
Cross-linked aggregates of penicillin acylase: Robust catalysts for the synthesis of β-lactam antibiotics
-
Cao L, van Langen F, van Rantwijk F, Sheldon R. Cross-linked aggregates of penicillin acylase: robust catalysts for the synthesis of β-lactam antibiotics. J Mol Catal B: Enzymatic 2001;11:665-70.
-
(2001)
J Mol Catal B: Enzymatic
, vol.11
, pp. 665-670
-
-
Cao, L.1
Van Langen, F.2
Van Rantwijk, F.3
Sheldon, R.4
-
9
-
-
0002363834
-
Effect of temperature on enzymatic synthesis of cephalosporins
-
Pandit U, editor. New York: Plenum Press
-
Baldaro E. Effect of temperature on enzymatic synthesis of cephalosporins. In: Pandit U, editor. Chemistry in healthcare and technology. New York: Plenum Press, 1991:237-40.
-
(1991)
Chemistry in Healthcare and Technology
, pp. 237-240
-
-
Baldaro, E.1
-
10
-
-
0032842539
-
Thermodynamically controlled synthesis of cefamandole
-
Nierstrasz V, Schroën C, Bosma R, Kroon P, Beeftink H, Janssen A, Tramper J. Thermodynamically controlled synthesis of cefamandole. Biocatal Biotransform 1999;17:209-23.
-
(1999)
Biocatal Biotransform
, vol.17
, pp. 209-223
-
-
Nierstrasz, V.1
Schroën, C.2
Bosma, R.3
Kroon, P.4
Beeftink, H.5
Janssen, A.6
Tramper, J.7
-
11
-
-
0034135625
-
Enzymatic synthesis of cephalothin by penicillin G acylase
-
Shaw S, Shyu J, Hsieh Y, Yeh H. Enzymatic synthesis of cephalothin by penicillin G acylase. Enzyme Microb Technol 2000;26:142-51.
-
(2000)
Enzyme Microb Technol
, vol.26
, pp. 142-151
-
-
Shaw, S.1
Shyu, J.2
Hsieh, Y.3
Yeh, H.4
-
12
-
-
0035906795
-
Predicting when precipitation-driven synthesis is feasible: Application to biocatalysis
-
Ulijn R, Janssen A, Moore D, Halling P. Predicting when precipitation-driven synthesis is feasible: application to biocatalysis. Chem Eur J 2001;7:2089-98.
-
(2001)
Chem Eur J
, vol.7
, pp. 2089-2098
-
-
Ulijn, R.1
Janssen, A.2
Moore, D.3
Halling, P.4
-
13
-
-
0032922615
-
Thermodynamically controlled synthesis of β-lactam antibiotics, equilibrium concentration and side-chain properties
-
Schroën C, Nierstrasz V, Kroon P, Bosma R, Janssen A, Beeftink H, Tramper J. Thermodynamically controlled synthesis of β-lactam antibiotics, equilibrium concentration and side-chain properties. Enzyme Microb Technol 1999;24:498-506.
-
(1999)
Enzyme Microb Technol
, vol.24
, pp. 498-506
-
-
Schroën, C.1
Nierstrasz, V.2
Kroon, P.3
Bosma, R.4
Janssen, A.5
Beeftink, H.6
Tramper, J.7
-
14
-
-
0032787978
-
Enzymatic synthesis of β-lactam antibiotics using penicillin-G acylase in frozen media
-
van Langen L, de Vroom E, van Rantwijk F, Sheldon R. Enzymatic synthesis of β-lactam antibiotics using penicillin-G acylase in frozen media. FEBS Lett 1999;456:89-92.
-
(1999)
FEBS Lett
, vol.456
, pp. 89-92
-
-
Van Langen, L.1
De Vroom, E.2
Van Rantwijk, F.3
Sheldon, R.4
-
15
-
-
0035811256
-
Highly efficient synthesis of ampicillin in an aqueous solution precipitate system: Repetitive addition of substrates in a semi-continuous process
-
Youshko M, van Langen L, de Vroom E, van Rantwijk F, Sheldon R, Švedas V. Highly efficient synthesis of ampicillin in an aqueous solution precipitate system: repetitive addition of substrates in a semi-continuous process. Biotechnol Bioeng 2001;73:426-30.
-
(2001)
Biotechnol Bioeng
, vol.73
, pp. 426-430
-
-
Youshko, M.1
Van Langen, L.2
De Vroom, E.3
Van Rantwijk, F.4
Sheldon, R.5
Švedas, V.6
-
16
-
-
0036176917
-
A kinetic examination of penicillin acylase stability in water-organic solvent systems at different temperatures
-
Arroyo M, Torres-Guzmán R, de la Mata I, Castillón M, Acebal C. A kinetic examination of penicillin acylase stability in water-organic solvent systems at different temperatures. Biocatal Biotransform 2002;20:53-6.
-
(2002)
Biocatal Biotransform
, vol.20
, pp. 53-56
-
-
Arroyo, M.1
Torres-Guzmán, R.2
De La Mata, I.3
Castillón, M.4
Acebal, C.5
-
18
-
-
0035931395
-
Kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in the presence of organic cosolvents
-
Illanes A, Fajardo A. Kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in the presence of organic cosolvents. J Mol Catal B: Enzymatic 2001;11:605-13.
-
(2001)
J Mol Catal B: Enzymatic
, vol.11
, pp. 605-613
-
-
Illanes, A.1
Fajardo, A.2
-
19
-
-
0034041263
-
Activation and stabilization of penicillin V acylase from Streptomyces lavendulae in the presence of glycerol and glycols
-
Arroyo M, Torres-Guzmán R, de la Mata I, Castillón M, Acebal C. Activation and stabilization of penicillin V acylase from Streptomyces lavendulae in the presence of glycerol and glycols. Biotechnol Prog 2000;16:368-71.
-
(2000)
Biotechnol Prog
, vol.16
, pp. 368-371
-
-
Arroyo, M.1
Torres-Guzmán, R.2
De La Mata, I.3
Castillón, M.4
Acebal, C.5
-
20
-
-
0036176917
-
A kinetic examination of penicillin acylase stability in water-organic solvent systems at different temperatures
-
Arroyo M, Torres-Guzmán R, de la Mata I, Castillón M, Acebal C. A kinetic examination of penicillin acylase stability in water-organic solvent systems at different temperatures. Biocatal Biotransform 2002;20:53-6.
-
(2002)
Biocatal Biotransform
, vol.20
, pp. 53-56
-
-
Arroyo, M.1
Torres-Guzmán, R.2
De La Mata, I.3
Castillón, M.4
Acebal, C.5
-
21
-
-
0036219285
-
Optimization of yield in the kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in organic media
-
Illanes A, Anjarí S, Arrieta R, Aguirre C. Optimization of yield in the kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in organic media. Appl Biochem Biotechnol 2002;97:165-80.
-
(2002)
Appl Biochem Biotechnol
, vol.97
, pp. 165-180
-
-
Illanes, A.1
Anjarí, S.2
Arrieta, R.3
Aguirre, C.4
-
22
-
-
0027909727
-
Stabilization of heterodimeric enzyme by multipoint covalent attachment: Penicillin G acylase from Kluyvera citrophila
-
Guisán J, Alvaro G, Fernández-Lafuente R, Rosell C, García J, Tagliani M. Stabilization of heterodimeric enzyme by multipoint covalent attachment: penicillin G acylase from Kluyvera citrophila. Biotechnol Bioeng 1993;42:455-64.
-
(1993)
Biotechnol Bioeng
, vol.42
, pp. 455-464
-
-
Guisán, J.1
Alvaro, G.2
Fernández-Lafuente, R.3
Rosell, C.4
García, J.5
Tagliani, M.6
-
23
-
-
0032890111
-
Facile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: Dramatic stabilization of penicillin acylase versus organic solvents
-
Fernández-Lafuente R, Rosell C, Canaan-Haden L, Rodes L, Guisán J. Facile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: dramatic stabilization of penicillin acylase versus organic solvents. Enzyme Microb Technol 1999;24:96-103.
-
(1999)
Enzyme Microb Technol
, vol.24
, pp. 96-103
-
-
Fernández-Lafuente, R.1
Rosell, C.2
Canaan-Haden, L.3
Rodes, L.4
Guisán, J.5
-
24
-
-
0343446120
-
Synthesis of antibiotics (cephaloglycin) catalyzed by penicillin G acylase: Evaluation and optimization of different synthetic approaches
-
Fernández-Lafuente R, Rosell C, Piatkowska B, Guisán J. Synthesis of antibiotics (cephaloglycin) catalyzed by penicillin G acylase: evaluation and optimization of different synthetic approaches. Enzyme Microb Technol 1996;19:9-14.
-
(1996)
Enzyme Microb Technol
, vol.19
, pp. 9-14
-
-
Fernández-Lafuente, R.1
Rosell, C.2
Piatkowska, B.3
Guisán, J.4
-
25
-
-
0032189174
-
The presence of methanol exerts a strong and complex modulation effect on the synthesis of different antibiotics by immobilized penicillin G acylase
-
Fernández-Lafuente R, Rosell C, Guisán J. The presence of methanol exerts a strong and complex modulation effect on the synthesis of different antibiotics by immobilized penicillin G acylase. Enzyme Microb Technol 1998;23:305-10.
-
(1998)
Enzyme Microb Technol
, vol.23
, pp. 305-310
-
-
Fernández-Lafuente, R.1
Rosell, C.2
Guisán, J.3
-
26
-
-
0032486573
-
Use of aqueous two-phase system for in situ extraction of water soluble antibiotics during their synthesis by enzymes immobilized on porous supports
-
Hernández-Jústiz O, Fernández-Lafuente R, Terreni M, Guisán J. Use of aqueous two-phase system for in situ extraction of water soluble antibiotics during their synthesis by enzymes immobilized on porous supports. Biotechnol Bioeng 1998;59:73-9.
-
(1998)
Biotechnol Bioeng
, vol.59
, pp. 73-79
-
-
Hernández-Jústiz, O.1
Fernández-Lafuente, R.2
Terreni, M.3
Guisán, J.4
-
27
-
-
0024029957
-
Aldehyde-agarose gels as activated supports for immobilization- stabilization of enzymes
-
Guisán J. Aldehyde-agarose gels as activated supports for immobilization-stabilization of enzymes. Enzyme Microb Technol 1988;10:375-82.
-
(1988)
Enzyme Microb Technol
, vol.10
, pp. 375-382
-
-
Guisán, J.1
-
29
-
-
0022340486
-
Ampicillin and cephalexin synthesis catalyzed by E. coli penicillin amidase. Yield increase due to substrate recycling
-
Kasche V. Ampicillin and cephalexin synthesis catalyzed by E. coli penicillin amidase. Yield increase due to substrate recycling. Biotechnol Lett 1985;12:877-82.
-
(1985)
Biotechnol Lett
, vol.12
, pp. 877-882
-
-
Kasche, V.1
-
30
-
-
0022093342
-
Reaction kinetics of cephalexin synthesizing enzyme from Xanthomonas citri
-
Nam D, Kim C, Ryu D. Reaction kinetics of cephalexin synthesizing enzyme from Xanthomonas citri. Biotechnol Bioeng 1985;28:943-60.
-
(1985)
Biotechnol Bioeng
, vol.28
, pp. 943-960
-
-
Nam, D.1
Kim, C.2
Ryu, D.3
-
31
-
-
0027656450
-
Enhancement effect of water activity on enzymatic synthesis of cephalexin
-
Hyun C, Kim J, Ryu D. Enhancement effect of water activity on enzymatic synthesis of cephalexin. Biotechnol Bioeng 1993;42:800-6.
-
(1993)
Biotechnol Bioeng
, vol.42
, pp. 800-806
-
-
Hyun, C.1
Kim, J.2
Ryu, D.3
-
32
-
-
0030568593
-
Effect of organic solvents on penicillin acylase-catalyzed reactions: Interaction of organic solvents with enzymes
-
Kim M, Lee S. Effect of organic solvents on penicillin acylase-catalyzed reactions: interaction of organic solvents with enzymes. J Mol Catal B: Enzymatic 1996;1:181-90.
-
(1996)
J Mol Catal B: Enzymatic
, vol.1
, pp. 181-190
-
-
Kim, M.1
Lee, S.2
-
33
-
-
0036844577
-
Effect of cosolvent and pH on the kinetically controlled synthesis of cephalexin with immobilised penicillin acylase
-
Aguirre C, Toledo M, Medina V, Illanes A. Effect of cosolvent and pH on the kinetically controlled synthesis of cephalexin with immobilised penicillin acylase. Process Biochem 2002;38:351-60.
-
(2002)
Process Biochem
, vol.38
, pp. 351-360
-
-
Aguirre, C.1
Toledo, M.2
Medina, V.3
Illanes, A.4
-
34
-
-
0022630151
-
Mechanism and yields in enzyme catalysed equilibrium and kinetically controlled synthesis of β-lactam antibiotics, peptides and other condensation products
-
Kasche V. Mechanism and yields in enzyme catalysed equilibrium and kinetically controlled synthesis of β-lactam antibiotics, peptides and other condensation products. Enzyme Microb Technol 1986;8:4-16.
-
(1986)
Enzyme Microb Technol
, vol.8
, pp. 4-16
-
-
Kasche, V.1
-
35
-
-
0030568603
-
Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in water-methanol mixtures: Effect of cosolvent content and chemical nature of substrate on reaction yields
-
Kim M, Lee S. Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in water-methanol mixtures: effect of cosolvent content and chemical nature of substrate on reaction yields. J Mol Catal B: Enzymatic 1996;1:201-11.
-
(1996)
J Mol Catal B: Enzymatic
, vol.1
, pp. 201-211
-
-
Kim, M.1
Lee, S.2
-
36
-
-
0033179764
-
Kinetically controlled synthesis catalyzed by proteases in reverse micelles and separation of precursor dipeptides of RGD
-
Chen Y, Zhang Z, Chen S, You D, Wu X, Yang X, Guan W. Kinetically controlled synthesis catalyzed by proteases in reverse micelles and separation of precursor dipeptides of RGD. Enzyme Microb Technol 1999;25:310-5.
-
(1999)
Enzyme Microb Technol
, vol.25
, pp. 310-315
-
-
Chen, Y.1
Zhang, Z.2
Chen, S.3
You, D.4
Wu, X.5
Yang, X.6
Guan, W.7
-
37
-
-
0002077184
-
Cosolvent effect on the synthesis of ampicillin and cephalexin with penicillin acylase
-
Ballesteros A, Plou F, Iborra J, Hailing P, editors. Amsterdam: Elsevier
-
Aguirre C, Baeza J, Illanes A. Cosolvent effect on the synthesis of ampicillin and cephalexin with penicillin acylase. In: Ballesteros A, Plou F, Iborra J, Hailing P, editors. Stability and stabilization of biocatalysts. Amsterdam: Elsevier, 1988:95-100.
-
(1988)
Stability and Stabilization of Biocatalysts
, pp. 95-100
-
-
Aguirre, C.1
Baeza, J.2
Illanes, A.3
-
38
-
-
0035810691
-
Modelling of enzymatic kinetic synthesis of cephalexin-influence of substrate concentration and temperature
-
Schroën C, Nierstrasz V, Moody H, Hoogschagen M, Kroon P, Bosma R, Beeftink H, Janssen A, Tramper J. Modelling of enzymatic kinetic synthesis of cephalexin-influence of substrate concentration and temperature. Biotechnol Bioeng 2001;73:171-8.
-
(2001)
Biotechnol Bioeng
, vol.73
, pp. 171-178
-
-
Schroën, C.1
Nierstrasz, V.2
Moody, H.3
Hoogschagen, M.4
Kroon, P.5
Bosma, R.6
Beeftink, H.7
Janssen, A.8
Tramper, J.9
-
39
-
-
0036720245
-
Enzymatic synthesis of cephalexin in aqueous two-pahse systems
-
Wei D, Zhu J, Cao X. Enzymatic synthesis of cephalexin in aqueous two-pahse systems. Biochem Eng J 2002;11:95-9.
-
(2002)
Biochem Eng J
, vol.11
, pp. 95-99
-
-
Wei, D.1
Zhu, J.2
Cao, X.3
-
42
-
-
15844369202
-
Thermal inactivation of penicillin acylase in the presence of substrate and products
-
Illanes A, Altamirano C, Zuñiga M. Thermal inactivation of penicillin acylase in the presence of substrate and products. Biotechnol Bioeng 1996;50:609-16.
-
(1996)
Biotechnol Bioeng
, vol.50
, pp. 609-616
-
-
Illanes, A.1
Altamirano, C.2
Zuñiga, M.3
|