Modeling of the enzymatic kinetic synthesis of cephalexin - Influence of substrate concentration and temperature

Biotechnology and Bioengineering

Volumn 73, Issue 3, 2001, Pages 171-178

  Schroen, C G P H ^a,b   Nierstrasz, V A ^a   Moody, H M ^a   Hoogschagen, M J ^a   Kroon, P J ^a   Bosma, R ^a   Beeftink, H H ^a   Janssen, A E M ^a   Tramper, J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b DSM RESEARCH   (Netherlands)

Author keywords

Antibiotic synthesis; Cephalexin; Kinetic model; Kinetic synthesis

Indexed keywords

ENZYME KINETICS; ENZYMES; HYDROLYSIS; SUBSTRATES; THERMAL EFFECTS;

SYNTHESIS REACTIONS;

BIOTECHNOLOGY;

7 AMINODEACETOXYCEPHALOSPORANIC ACID; AMIDASE; CEFALEXIN; PENICILLIN G ACYLASE; PHENYLGLYCINE; PHENYLGLYCINE AMIDE; PHENYLGLYCINE METHYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; DRUG SYNTHESIS; ENTHALPY; ENZYME SUBSTRATE; HYDROLYSIS; PH; REACTION ANALYSIS; RELIABILITY; TEMPERATURE DEPENDENCE;

EID: 0035810691     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.1049     Document Type: Article

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