Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology and Applied Pharmacology

Volumn 154, Issue 3, 1999, Pages 279-286

  Walker, Nigel J ^a   Portier, Christopher J ^a   Lax, Sigurd F ^b   Crofts, Frances G ^b   Li, Ying ^b   Lucier, George W ^a   Sutter, Thomas R ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

CYP1A1; CYP1A2; CYP1B1; Cytochrome P 450; Dioxin; Dose response; Liver; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 ISOENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; FEMALE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER METABOLISM; LIVER TOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXICOKINETICS;

ANIMALIA;

EID: 0032972954     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8595     Document Type: Article

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