SCOPUS 정보 검색 플랫폼

Volumn 892, Issue 1, 2001, Pages 94-101

The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K+ channels TREK-1 and TRAAK

(8) Meadows, H J a Chapman, C G a Duckworth, D M a Kelsell, R E a Murdock, P R a Nasir, S a Rennie, G a Randall, A D a

a GLAXOSMITHKLINE (United Kingdom)

Author keywords

Lamotrigine; Potassium channel; Sipatrigine; Two pore domain

Indexed keywords

ANTICONVULSIVE AGENT; ARACHIDONIC ACID; COMPLEMENTARY DNA; LAMOTRIGINE; MESSENGER RNA; NEUROPROTECTIVE AGENT; POTASSIUM CHANNEL; SIPATRIGINE;

ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HYPERPOLARIZATION; MEMBRANE CONDUCTANCE; MEMBRANE CURRENT; MEMBRANE STEADY POTENTIAL; MOLECULAR CLONING; NEUROPROTECTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CELL LINE; FEMALE; HUMANS; MALE; MEMBRANE POTENTIALS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; OOCYTES; PIPERAZINES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PYRIMIDINES; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; XENOPUS LAEVIS;

EID: 0035895804 PISSN: 00068993 EISSN: None Source Type: Journal
DOI: 10.1016/S0006-8993(00)03239-X Document Type: Article

Times cited : (54)

References (18)

1
- 0030821520
- + channel to sense external pH variations near physiological pH
- (1997) EMBO J. , vol.16 , pp. 5464-5471
- Duprat, F.¹ Lesage, F.² Fink, M.³ Reyes, R.⁴ Heurteaux, C.⁵ Lazdunski, M.⁶

2
- 0034015102
- + channels TREK-1 and TRAAK
- (2000) Mol. Pharmacol. , vol.57 , pp. 906-912
- Duprat, F.¹ Lesage, F.² Patel, A.J.³ Fink, M.⁴ Romey, G.⁵ Lazdunski, M.⁶

3
- 0032526428
- + channel stimulated by arachidonic acid and polyunsaturated fatty acids
- (1998) EMBO J. , vol.17 , pp. 3297-3308
- Fink, M.¹ Lesage, F.² Duprat, F.³ Heurteaux, C.⁴ Reyes, R.⁵ Fosset, M.⁶ Lazdunski, M.⁷

4
- 0032750453
- Mechanisms of ischaemic damage to central white matter axons: A quantitative histological analysis using rat optic nerve
- (1999) Neuroscience , vol.94 , pp. 1219-1230
- Garthwaite, G.¹ Brown, G.² Batchelor, A.M.³ Goodwin, D.A.⁴ Garthwaite, J.⁵

5
- 0033847175
- Sipatrigine (BW 619C89) is a neuroprotective agent and a sodium and calcium channel inhibitor
- (2000) CNS Drug Rev. , vol.6 , pp. 111-134
- Hainsworth, A.H.¹ Stefani, A.² Calabresi, P.³ Smith, T.W.⁴ Leach, M.J.⁵

6
- 0034678889
- Polyunsaturated fatty acids are potent neuroprotectors
- (2000) EMBO J. , vol.19 , pp. 1784-1793
- Lauritzen, I.¹ Blondeau, N.² Heurteaux, C.³ Widmann, C.⁴ Romey, G.⁵ Lazdunski, M.⁶

7
- 0029871919
- + channel with a novel structure
- (1996) EMBO J. , vol.15 , pp. 1004-1011
- Lesage, F.¹ Guillemare, E.² Fink, M.³ Duprat, F.⁴ Lazdunski, M.⁵ Romey, G.⁶ Barhanin, J.⁷

8
- 0034646931
- Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel
- (2000) FEBS Lett. , vol.471 , pp. 137-140
- Lesage, F.¹ Maingret, F.² Lazdunski, M.³

9
- 0034117401
- 2+ channels by the neuroprotective agent BW619C89 (Sipatrigine)
- (2000) Neuropharmacology , vol.39 , pp. 1247-1253
- McNaughton, N.C.¹ Hainsworth, A.H.² Green, P.J.³ Randall, A.D.⁴

10
- 0031423748
- 2+ channels by the neuroprotective agent BW619C89
- (1997) Neuropharmacology , vol.36 , pp. 1795-1798
- McNaughton, N.C.¹ Leach, M.J.² Hainsworth, A.H.³ Randall, A.D.⁴

11
- 0034109513
- Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel
- (2000) Pflügers Arch. , vol.439 , pp. 714-722
- Meadows, H.J.¹ Benham, C.D.² Cairns, W.³ Gloger, I.⁴ Jennings, C.⁵ Medhurst, A.D.⁶ Murdock, P.⁷ Chapman, C.G.⁸

12
- 0033366538
- + channels
- (1999) Nat. Neurosci. , vol.2 , pp. 422-426
- Patel, A.J.¹ Honore, E.² Lesage, F.³ Fink, M.⁴ Romey, G.⁵ Lazdunski, M.⁶

13
- 0032479997
- + channel
- (1998) EMBO J. , vol.17 , pp. 4283-4290
- Patel, A.J.¹ Honore, E.² Maingret, F.³ Lesage, F.⁴ Fink, M.⁵ Duprat, F.⁶ Lazdunski, M.⁷

14
- 0032817289
- Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor
- (1999) Mol. Pharmacol. , vol.56 , pp. 657-663
- Sarau, H.M.¹ Ames, R.S.² Chambers, J.³ Ellis, C.⁴ Elshourbagy, N.⁵ Foley, J.J.⁶ Schmidt, D.B.⁷ Muccitelli, R.M.⁸ Jenkins, O.⁹ Murdock, P.R.¹⁰ Herrity, N.C.¹¹ Halsey, W.¹² Sathe, G.¹³ Muir, A.I.¹⁴ Nuthulaganti, P.¹⁵ Dytko, G.M.¹⁶ Buckley, P.T.¹⁷ Wilson, S.¹⁸ Bergsma, D.J.¹⁹ Hay, D.W.²⁰ more..

15
- 0031788811
- On the inhibition of voltage activated calcium currents in rat cortical neurones by the neuroprotective agent 619C89
- (1998) Br. J. Pharmacol. , vol.125 , pp. 1058-1064
- Stefani, A.¹ Hainsworth, A.H.² Spadoni, F.³ Bernardi, G.⁴

16
- 0027968068
- CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
- (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
- Thompson, J.D.¹ Higgins, D.G.² Gibson, T.J.³

17
- 0029075471
- + channels in rat hippocampal neurones
- (1995) Pflügers Arch. , vol.430 , pp. 437-446
- Xie, X.¹ Lancaster, B.² Peakman, T.³ Garthwaite, J.⁴

18
- 0029930668
- + channels
- (1996) Neuroscience , vol.73 , pp. 951-962
- Xie, X.M.¹ Garthwaite, J.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.