메뉴 건너뛰기




Volumn 23, Issue 20, 2005, Pages 4545-4552

Role of genomic markers in colorectal cancer treatment

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CETUXIMAB; DIHYDROPYRIMIDINE DEHYDROGENASE; DNA TOPOISOMERASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUOROURACIL; GEFITINIB; IRINOTECAN; OXALIPLATIN; PANITUMUMAB; PROTEIN P53; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TUMOR MARKER; VATALANIB; XERODERMA PIGMENTOSUM GROUP D PROTEIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DRUG DERIVATIVE; PLATINUM COMPLEX;

EID: 22844431902     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.19.752     Document Type: Review
Times cited : (60)

References (83)
  • 1
    • 0028940399 scopus 로고
    • Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
    • Johnston PG, Lenz HJ, Leichman CG, et al: Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 55:1407-1412, 1995
    • (1995) Cancer Res , vol.55 , pp. 1407-1412
    • Johnston, P.G.1    Lenz, H.J.2    Leichman, C.G.3
  • 2
    • 0031426423 scopus 로고    scopus 로고
    • Immunohistochemical determination of thymidylate synthase in colorectal cancer-methodological studies
    • Edler D, Blomgren H, Allegra CJ, et al: Immunohistochemical determination of thymidylate synthase in colorectal cancer-methodological studies. Eur J Cancer 33:2278-2281, 1997
    • (1997) Eur J Cancer , vol.33 , pp. 2278-2281
    • Edler, D.1    Blomgren, H.2    Allegra, C.J.3
  • 3
    • 15444349773 scopus 로고    scopus 로고
    • p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
    • Lenz HJ, Danenberg KD, Leichman CG, et al: p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site. Clin Cancer Res 4:1227-1234, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 1227-1234
    • Lenz, H.J.1    Danenberg, K.D.2    Leichman, C.G.3
  • 4
    • 0035213225 scopus 로고    scopus 로고
    • Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells
    • Takebe N, Zhao SC, Ural AU, et al: Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells. Cancer Gene Ther 8: 966-973, 2001
    • (2001) Cancer Gene Ther , vol.8 , pp. 966-973
    • Takebe, N.1    Zhao, S.C.2    Ural, A.U.3
  • 5
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • Salonga D, Danenberg KD, Johnson M, et al: Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 6:1322-1327, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 1322-1327
    • Salonga, D.1    Danenberg, K.D.2    Johnson, M.3
  • 6
    • 0035522659 scopus 로고    scopus 로고
    • Thymidylate synthase pharmacogenetics in colorectal cancer
    • Marsh S, McLeod HL: Thymidylate synthase pharmacogenetics in colorectal cancer. Clin Colorectal Cancer 1:1751-81, 2001
    • (2001) Clin Colorectal Cancer , vol.1 , pp. 1751-1781
    • Marsh, S.1    McLeod, H.L.2
  • 7
    • 0033427561 scopus 로고    scopus 로고
    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • Kawakami K, Omura K, Kanehira E, et al: Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 19:3249-3252, 1999
    • (1999) Anticancer Res , vol.19 , pp. 3249-3252
    • Kawakami, K.1    Omura, K.2    Kanehira, E.3
  • 8
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger R, Danenberg K, Leichman CG, et al: High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res 4:2371-2376, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3
  • 9
    • 0029960772 scopus 로고    scopus 로고
    • Expression of thymidine phosphorylase in human gastric carcinoma
    • Takebayashi Y, Miyadera K, Akiyama S, et al: Expression of thymidine phosphorylase in human gastric carcinoma. Jpn J Cancer Res 87:288-295, 1996
    • (1996) Jpn J Cancer Res , vol.87 , pp. 288-295
    • Takebayashi, Y.1    Miyadera, K.2    Akiyama, S.3
  • 10
    • 11144303556 scopus 로고    scopus 로고
    • Tumor dihydropyrimidine dehydrogenase expression is a useful marker in adjuvant therapy with oral fluoropyrimidines after curative resection of colorectal cancer
    • Tsuji T, Sawai T, Takeshita H, et al: Tumor dihydropyrimidine dehydrogenase expression is a useful marker in adjuvant therapy with oral fluoropyrimidines after curative resection of colorectal cancer. Cancer Chemother Pharmacol 54:531-536, 2004
    • (2004) Cancer Chemother Pharmacol , vol.54 , pp. 531-536
    • Tsuji, T.1    Sawai, T.2    Takeshita, H.3
  • 11
    • 9144264837 scopus 로고    scopus 로고
    • Tumor dihydropyrimidine dehydrogenase in stage II and III colorectal cancer: Low level expression is a beneficial marker in oral-adjuvant chemotherapy, but is also a predictor for poor prognosis in patients treated with curative surgery alone
    • Tsuji T, Sawai T, Takeshita H, et al: Tumor dihydropyrimidine dehydrogenase in stage II and III colorectal cancer: Low level expression is a beneficial marker in oral-adjuvant chemotherapy, but is also a predictor for poor prognosis in patients treated with curative surgery alone. Cancer Lett 204:97-104, 2004
    • (2004) Cancer Lett , vol.204 , pp. 97-104
    • Tsuji, T.1    Sawai, T.2    Takeshita, H.3
  • 12
    • 2542482632 scopus 로고    scopus 로고
    • p53 is an independent pre-treatment markers for long-term survival in stage II and III colorectal cancers: An analysis of interaction between genetic markers and fluorouracil-based adjuvant therapy
    • Tang R, Wang JY, Fan CW, et al: p53 is an independent pre-treatment markers for long-term survival in stage II and III colorectal cancers: An analysis of interaction between genetic markers and fluorouracil-based adjuvant therapy. Cancer Lett 210:101-109, 2004
    • (2004) Cancer Lett , vol.210 , pp. 101-109
    • Tang, R.1    Wang, J.Y.2    Fan, C.W.3
  • 13
    • 0032521205 scopus 로고    scopus 로고
    • Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study
    • Ahnen DJ, Feigl P, Quan G, et al: Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study. Cancer Res 58: 1149-1158, 1998
    • (1998) Cancer Res , vol.58 , pp. 1149-1158
    • Ahnen, D.J.1    Feigl, P.2    Quan, G.3
  • 14
    • 0035576102 scopus 로고    scopus 로고
    • ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
    • Shirota Y, Stoehlmacher J, Brabender J, et al: ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol 19:4298-4304, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 4298-4304
    • Shirota, Y.1    Stoehlmacher, J.2    Brabender, J.3
  • 15
    • 0035893755 scopus 로고    scopus 로고
    • A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer
    • Park DJ, Stoehlmacher J, Zhang W, et al: A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res 61:8654-8658, 2001
    • (2001) Cancer Res , vol.61 , pp. 8654-8658
    • Park, D.J.1    Stoehlmacher, J.2    Zhang, W.3
  • 16
    • 0031046059 scopus 로고    scopus 로고
    • CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinants
    • Jansen WJ, Zwart B, Hulscher ST, et al: CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinants. Int J Cancer 70:335-340, 1997
    • (1997) Int J Cancer , vol.70 , pp. 335-340
    • Jansen, W.J.1    Zwart, B.2    Hulscher, S.T.3
  • 17
    • 0024959672 scopus 로고
    • Clinical and pathological associations with allelic loss in colorectal carcinoma
    • Kern SE, Fearon ER, Tersmette KW, et al: Clinical and pathological associations with allelic loss in colorectal carcinoma. JAMA 261:3099-3103, 1989
    • (1989) JAMA , vol.261 , pp. 3099-3103
    • Kern, S.E.1    Fearon, E.R.2    Tersmette, K.W.3
  • 18
    • 0029856557 scopus 로고    scopus 로고
    • Three distinct signalling responses by murine fibroblasts to genotoxic stress
    • Liu ZG, Baskaran R, Lea-Chou ET, et al: Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 384:273-276, 1996
    • (1996) Nature , vol.384 , pp. 273-276
    • Liu, Z.G.1    Baskaran, R.2    Lea-Chou, E.T.3
  • 19
    • 17944365210 scopus 로고    scopus 로고
    • p53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy
    • Buglioni S, D'Agnano I, Vasselli S, et al: p53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy. Am J Clin Pathol 116:360-368, 2001
    • (2001) Am J Clin Pathol , vol.116 , pp. 360-368
    • Buglioni, S.1    D'Agnano, I.2    Vasselli, S.3
  • 20
    • 0035102240 scopus 로고    scopus 로고
    • Dukes B colorectal cancer: Distinct genetic categories and clinical outcome based on proximal or distal tumor location
    • Gervaz P, Bouzourene H, Cerottini JP, et al: Dukes B colorectal cancer: Distinct genetic categories and clinical outcome based on proximal or distal tumor location. Dis Colon Rectum 44:364-373, 2001
    • (2001) Dis Colon Rectum , vol.44 , pp. 364-373
    • Gervaz, P.1    Bouzourene, H.2    Cerottini, J.P.3
  • 21
    • 0034026701 scopus 로고    scopus 로고
    • p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer
    • Bouzourene H, Gervaz P, Cerottini JP, et al: p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer. Eur J Cancer 36:1008-1015, 2000
    • (2000) Eur J Cancer , vol.36 , pp. 1008-1015
    • Bouzourene, H.1    Gervaz, P.2    Cerottini, J.P.3
  • 22
    • 0037440051 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    • Allegra CJ, Paik S, Colangelo LH, et al: Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 21:241-250, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 241-250
    • Allegra, C.J.1    Paik, S.2    Colangelo, L.H.3
  • 23
    • 0033570235 scopus 로고    scopus 로고
    • Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma
    • Giatromanolaki A, Stathopoulos GP, Tsiobanou E, et al: Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer 86:1421-1430, 1999
    • (1999) Cancer , vol.86 , pp. 1421-1430
    • Giatromanolaki, A.1    Stathopoulos, G.P.2    Tsiobanou, E.3
  • 24
    • 0030753698 scopus 로고    scopus 로고
    • p53 alterations are associated with improved prognosis in distal colonic carcinomas
    • Soong R, Grieu F, Bobbins P, et al: p53 alterations are associated with improved prognosis in distal colonic carcinomas. Clin Cancer Res 3:1405-1411, 1997
    • (1997) Clin Cancer Res , vol.3 , pp. 1405-1411
    • Soong, R.1    Grieu, F.2    Bobbins, P.3
  • 25
    • 0035062049 scopus 로고    scopus 로고
    • Molecular markers are predictors of recurrence and survival in patients with Dukes B and Dukes C colorectal adenocarcinoma
    • Bhatavdekar JM, Patel DD, Chikhlikar PR, et al: Molecular markers are predictors of recurrence and survival in patients with Dukes B and Dukes C colorectal adenocarcinoma. Dis Colon Rectum 44:523-533, 2001
    • (2001) Dis Colon Rectum , vol.44 , pp. 523-533
    • Bhatavdekar, J.M.1    Patel, D.D.2    Chikhlikar, P.R.3
  • 26
    • 0029955460 scopus 로고    scopus 로고
    • The DCC protein and prognosis in colorectal cancer
    • Shibata D, Reale MA, Lavin P, et al: The DCC protein and prognosis in colorectal cancer. N Engl J Med 335:1727-1732, 1996
    • (1996) N Engl J Med , vol.335 , pp. 1727-1732
    • Shibata, D.1    Reale, M.A.2    Lavin, P.3
  • 27
    • 0031827793 scopus 로고    scopus 로고
    • Chromosome 18q allelic loss and prognosis in stage II and III colon cancer
    • Lanza G, Matteuzzi M, Gafa R, et al: Chromosome 18q allelic loss and prognosis in stage II and III colon cancer. Int J Cancer 79:390-395, 1998
    • (1998) Int J Cancer , vol.79 , pp. 390-395
    • Lanza, G.1    Matteuzzi, M.2    Gafa, R.3
  • 28
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu TT, Catalano PJ, et al: Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 344:1196-1206, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3
  • 29
    • 0025056930 scopus 로고
    • Identification of a chromosome 18q gene that is altered in colorectal cancers
    • Fearon ER, Cho KR, Nigro JM, et al: Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247:49-56, 1990
    • (1990) Science , vol.247 , pp. 49-56
    • Fearon, E.R.1    Cho, K.R.2    Nigro, J.M.3
  • 30
    • 0031006336 scopus 로고    scopus 로고
    • MAD-related genes on 18q21.1, Smad2 and Smad4, are altered infrequently in esophageal squamous cell carcinoma
    • Maesawa C, Tamura G, Nishizuka S, et al: MAD-related genes on 18q21.1, Smad2 and Smad4, are altered infrequently in esophageal squamous cell carcinoma. Jpn J Cancer Res 88:340-343, 1997
    • (1997) Jpn J Cancer Res , vol.88 , pp. 340-343
    • Maesawa, C.1    Tamura, G.2    Nishizuka, S.3
  • 31
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353, 1996
    • (1996) Science , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 32
    • 0031041254 scopus 로고    scopus 로고
    • Colorectal carcinogenesis: From chromosomal evolution pathways to molecular pathogenesis
    • Remvikos Y, Muleris M, Salmon RJ, et al: Colorectal carcinogenesis: From chromosomal evolution pathways to molecular pathogenesis. Cancer Genet Cytogenet 93:63-73, 1997
    • (1997) Cancer Genet Cytogenet , vol.93 , pp. 63-73
    • Remvikos, Y.1    Muleris, M.2    Salmon, R.J.3
  • 33
    • 9144226978 scopus 로고    scopus 로고
    • Screening for defective DNA mismatch repair in stage II and III colorectal cancer patients
    • Chai SM, Zeps N, Shearwood AM, et al: Screening for defective DNA mismatch repair in stage II and III colorectal cancer patients. Clin Gastroenterol Hepatol 2:1017-1025, 2004
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 1017-1025
    • Chai, S.M.1    Zeps, N.2    Shearwood, A.M.3
  • 34
    • 0034642605 scopus 로고    scopus 로고
    • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
    • Gryfe R, Kim H, Hsieh ET, et al: Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 342:69-77, 2000
    • (2000) N Engl J Med , vol.342 , pp. 69-77
    • Gryfe, R.1    Kim, H.2    Hsieh, E.T.3
  • 35
    • 7444269881 scopus 로고    scopus 로고
    • Prognostic significance of microsatellite instability in sporadic colorectal cancer
    • Lim SB, Jeyong SY, Lee MR, et al: Prognostic significance of microsatellite instability in sporadic colorectal cancer. Int J Colorectal Dis 19:533-537, 2004
    • (2004) Int J Colorectal Dis , vol.19 , pp. 533-537
    • Lim, S.B.1    Jeyong, S.Y.2    Lee, M.R.3
  • 36
    • 0025705880 scopus 로고
    • Transforming growth factor-beta: Multifunctional regulator of differentiation and development
    • Roberts AB, Flanders KC, Heine UI, et al: Transforming growth factor-beta: Multifunctional regulator of differentiation and development. Philos Trans R Soc Lond B Biol Sci 327:145-154, 1990
    • (1990) Philos Trans R Soc Lond B Biol Sci , vol.327 , pp. 145-154
    • Roberts, A.B.1    Flanders, K.C.2    Heine, U.I.3
  • 37
    • 0025122809 scopus 로고
    • TGF-beta receptors and TGF-beta binding proteoglycans: Recent progress in identifying their functional properties
    • Massague J, Cheifetz S, Boyd FT, et al: TGF-beta receptors and TGF-beta binding proteoglycans: Recent progress in identifying their functional properties. Ann N Y Acad Sci 593:59-72, 1990
    • (1990) Ann N Y Acad Sci , vol.593 , pp. 59-72
    • Massague, J.1    Cheifetz, S.2    Boyd, F.T.3
  • 38
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB, et al: Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359:693-699, 1992
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 39
    • 0027531528 scopus 로고
    • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
    • Kulkarni AB, Huh CG, Becker D, et al: Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90:770-774, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 770-774
    • Kulkarni, A.B.1    Huh, C.G.2    Becker, D.3
  • 40
    • 0027412665 scopus 로고
    • Prognostic significance of K-ras mutations in colorectal carcinoma
    • Benhattar J, Losi L, Chaubert P, et al: Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 104: 1044-1048, 1993
    • (1993) Gastroenterology , vol.104 , pp. 1044-1048
    • Benhattar, J.1    Losi, L.2    Chaubert, P.3
  • 41
    • 0030499353 scopus 로고    scopus 로고
    • K-ras gene mutation is a useful predictor of the survival of early stage colorectal cancers
    • Lee JC, Wang ST, Lai MD, et al: K-ras gene mutation is a useful predictor of the survival of early stage colorectal cancers. Anticancer Res 16:3839-3844, 1996
    • (1996) Anticancer Res , vol.16 , pp. 3839-3844
    • Lee, J.C.1    Wang, S.T.2    Lai, M.D.3
  • 42
    • 0032490124 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The multicenter "RASCAL" study
    • Andreyev HJ, Norman AR, Cunningham D, et al: Kirsten ras mutations in patients with colorectal cancer: The multicenter "RASCAL" study. J Natl Cancer Inst 90:675-684, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 675-684
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 43
    • 0035444798 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study
    • Andreyev HJ, Norman AR, Cunningham D, et al: Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study. Br J Cancer 85:692-696, 2001
    • (2001) Br J Cancer , vol.85 , pp. 692-696
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 44
    • 0034856316 scopus 로고    scopus 로고
    • Capecitabine: A novel agent for the treatment of solid tumors
    • Johnston PG, Kaye S: Capecitabine: A novel agent for the treatment of solid tumors. Anticancer Drugs 12:639-646, 2001
    • (2001) Anticancer Drugs , vol.12 , pp. 639-646
    • Johnston, P.G.1    Kaye, S.2
  • 45
    • 0033989203 scopus 로고    scopus 로고
    • Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
    • Giacchetti S, Perpoint B, Zidani R, et al: Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 18:136-147, 2000
    • (2000) J Clin Oncol , vol.18 , pp. 136-147
    • Giacchetti, S.1    Perpoint, B.2    Zidani, R.3
  • 46
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD, et al: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial. Lancet 355:1041-1047, 2000
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3
  • 47
    • 0028982818 scopus 로고
    • Ratio of 2′-deoxyadenosine- 5′-triphosphate/ thymidine-5′-triphosphate influences the commitment of human colon carcinoma cells to thymineless death
    • Houghton JA, Tillman DM, Harwood FG: Ratio of 2′-deoxyadenosine- 5′-triphosphate/ thymidine-5′-triphosphate influences the commitment of human colon carcinoma cells to thymineless death. Clin Cancer Res 1:723-730, 1995
    • (1995) Clin Cancer Res , vol.1 , pp. 723-730
    • Houghton, J.A.1    Tillman, D.M.2    Harwood, F.G.3
  • 48
    • 0036906795 scopus 로고    scopus 로고
    • Future potential of thymidylate synthase inhibitors in cancer therapy
    • Lehman NL: Future potential of thymidylate synthase inhibitors in cancer therapy. Expert Opin Investig Drugs 11:1775-1787, 2002
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 1775-1787
    • Lehman, N.L.1
  • 49
    • 0026795489 scopus 로고
    • Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
    • Johnston PG, Drake JC, Trepel J, et al: Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res 52:4306-4312, 1992
    • (1992) Cancer Res , vol.52 , pp. 4306-4312
    • Johnston, P.G.1    Drake, J.C.2    Trepel, J.3
  • 50
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ER, Rockette HE, et al: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12:2640-2647, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3
  • 51
    • 0033981858 scopus 로고    scopus 로고
    • Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival
    • Edler D, Kressner U, Ragnhammar P, et al: Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival. Clin Cancer Res 6:488-492, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 488-492
    • Edler, D.1    Kressner, U.2    Ragnhammar, P.3
  • 52
    • 0035430487 scopus 로고    scopus 로고
    • Polymorphism in the thymidylate synthase promoter enhancer region in colorectal cancer
    • Marsh S, McKay JA, Cassidy J, et al: Polymorphism in the thymidylate synthase promoter enhancer region in colorectal cancer. Int J Oncol 19:383-386, 2001
    • (2001) Int J Oncol , vol.19 , pp. 383-386
    • Marsh, S.1    McKay, J.A.2    Cassidy, J.3
  • 53
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE: Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 16:215-237, 1989
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 54
    • 0032862086 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase in colorectal cancer
    • Johnston SJ, Ridge SA, Cassidy J, et al: Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. Clin Cancer Res 5:2566-2570, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2566-2570
    • Johnston, S.J.1    Ridge, S.A.2    Cassidy, J.3
  • 55
    • 0026503019 scopus 로고
    • Biophysical analysis of DNA modified by 1,2-diaminocyclohexane platinum(II) complexes
    • Boudny V, Vrana O, Gaucheron F, et al: Biophysical analysis of DNA modified by 1,2-diaminocyclohexane platinum(II) complexes. Nucleic Acids Res 20:267-272, 1992
    • (1992) Nucleic Acids Res , vol.20 , pp. 267-272
    • Boudny, V.1    Vrana, O.2    Gaucheron, F.3
  • 56
    • 0032820506 scopus 로고    scopus 로고
    • A review of the pharmacology and clinical activity of new chemotherapy agents for the treatment of colorectal cancer
    • Adjei AA: A review of the pharmacology and clinical activity of new chemotherapy agents for the treatment of colorectal cancer. Br J Clin Pharmacol 48:265-277, 1999
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 265-277
    • Adjei, A.A.1
  • 57
    • 0033566758 scopus 로고    scopus 로고
    • Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine- platinum (IV) (JM216) platinum intrastrand DNA diadducts
    • Reardon JT, Vaisman A, Chaney SG, et al: Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine- platinum (IV) (JM216) platinum intrastrand DNA diadducts. Cancer Res 59:3968-3971, 1999
    • (1999) Cancer Res , vol.59 , pp. 3968-3971
    • Reardon, J.T.1    Vaisman, A.2    Chaney, S.G.3
  • 59
    • 0027364921 scopus 로고
    • Human xeroderma pigmentosum group D gene encodes a DNA helicase
    • Sung P, Bailly V, Weber C, et al: Human xeroderma pigmentosum group D gene encodes a DNA helicase. Nature 365:852-855, 1993
    • (1993) Nature , vol.365 , pp. 852-855
    • Sung, P.1    Bailly, V.2    Weber, C.3
  • 61
    • 0029838307 scopus 로고    scopus 로고
    • DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata
    • Pommier Y, Kohlhagen G, Bailly C, et al: DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata. Biochemistry 35:13303-13309, 1996
    • (1996) Biochemistry , vol.35 , pp. 13303-13309
    • Pommier, Y.1    Kohlhagen, G.2    Bailly, C.3
  • 62
    • 0029926323 scopus 로고    scopus 로고
    • Adjuvant treatment of node-positive breast cancer with cyclophosphamide, doxorubicin, fluorouracil, and vincristine versus cyclophosphamide, methotrexate, and fluorouracil: Final report after a 16-year median follow-up duration
    • Misset JL, di Palma M, Delgado M, et al: Adjuvant treatment of node-positive breast cancer with cyclophosphamide, doxorubicin, fluorouracil, and vincristine versus cyclophosphamide, methotrexate, and fluorouracil: Final report after a 16-year median follow-up duration. J Clin Oncol 14:1136-1145, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 1136-1145
    • Misset, J.L.1    di Palma, M.2    Delgado, M.3
  • 63
    • 0030580064 scopus 로고    scopus 로고
    • Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase
    • Rivory LP, Bowles MR, Robert J, et al: Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase. Biochem Pharmacol 52:1103-1111, 1996
    • (1996) Biochem Pharmacol , vol.52 , pp. 1103-1111
    • Rivory, L.P.1    Bowles, M.R.2    Robert, J.3
  • 64
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang YH, Liu LF: Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48:1722-1726, 1988
    • (1988) Cancer Res , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 65
    • 0033214444 scopus 로고    scopus 로고
    • The EGF receptor as central transducer of heterologous signalling systems
    • Zwick E, Hackel PO, Prenzel N, et al: The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20:408-412, 1999
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 408-412
    • Zwick, E.1    Hackel, P.O.2    Prenzel, N.3
  • 66
    • 0033757346 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
    • suppl 1
    • Ciardiello F: Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents. Drugs 60:25-32, 41-42, 2000 (suppl 1)
    • (2000) Drugs , vol.60
    • Ciardiello, F.1
  • 68
    • 0027415146 scopus 로고
    • The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer
    • Mayer A, Takimoto M, Fritz E, et al: The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer. Cancer 71:2454-2460, 1993
    • (1993) Cancer , vol.71 , pp. 2454-2460
    • Mayer, A.1    Takimoto, M.2    Fritz, E.3
  • 69
    • 0036849596 scopus 로고    scopus 로고
    • Evaluation of the epidermal growth factor receptor (EGFR) in colorectal tumours and lymph node metastases
    • McKay JA, Murray LJ, Curran S, et al: Evaluation of the epidermal growth factor receptor (EGFR) in colorectal tumours and lymph node metastases. Eur J Cancer 38:2258-2264, 2002
    • (2002) Eur J Cancer , vol.38 , pp. 2258-2264
    • McKay, J.A.1    Murray, L.J.2    Curran, S.3
  • 70
    • 0347426783 scopus 로고    scopus 로고
    • Multicenter study of ABX-EGF monotherapy in patients with metastatic colorectal cancer
    • Meropol NJ, Berlin J, Hecht JR: Multicenter study of ABX-EGF monotherapy in patients with metastatic colorectal cancer. Proc Am Soc Clin Oncol 22:2003
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Meropol, N.J.1    Berlin, J.2    Hecht, J.R.3
  • 71
    • 0033941120 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer
    • Cascinu S, Staccioli MP, Gasparini G, et al: Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer. Clin Cancer Res 6:2803-2807, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 2803-2807
    • Cascinu, S.1    Staccioli, M.P.2    Gasparini, G.3
  • 72
    • 0031789314 scopus 로고    scopus 로고
    • Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
    • Ishigami SI, Arii S, Furutani M, et al: Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br J Cancer 78:1379-1384, 1998
    • (1998) Br J Cancer , vol.78 , pp. 1379-1384
    • Ishigami, S.I.1    Arii, S.2    Furutani, M.3
  • 73
    • 0347615101 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies
    • Morgan B, Thomas AL, Drevs J, et al: Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies. J Clin Oncol 21:3955-3964, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 3955-3964
    • Morgan, B.1    Thomas, A.L.2    Drevs, J.3
  • 74
    • 11244303546 scopus 로고    scopus 로고
    • Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells
    • Arango D, Wilson AJ, Shi Q, et al: Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells. Br J Cancer 91:1931-1946, 2004
    • (2004) Br J Cancer , vol.91 , pp. 1931-1946
    • Arango, D.1    Wilson, A.J.2    Shi, Q.3
  • 75
    • 9144273781 scopus 로고    scopus 로고
    • Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin
    • Mariadason JM, Arango D, Shi Q, et al: Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin. Cancer Res 63:8791-8812, 2003
    • (2003) Cancer Res , vol.63 , pp. 8791-8812
    • Mariadason, J.M.1    Arango, D.2    Shi, Q.3
  • 76
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, et al: Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science 286:531-537, 1999
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3
  • 77
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, van't Veer LJ, et al: A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347:1999-2009, 2002
    • (2002) N Engl J Med , vol.347 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3
  • 78
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SL, Huang CC, et al: Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8:816-824, 2002
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.2    Huang, C.C.3
  • 79
    • 0037688065 scopus 로고    scopus 로고
    • Using gene expression ratios to predict outcome among patients with mesothelioma
    • Gordon GJ, Jensen RV, Hsiao LL, et al: Using gene expression ratios to predict outcome among patients with mesothelioma. J Natl Cancer Inst 95:598-605, 2003
    • (2003) J Natl Cancer Inst , vol.95 , pp. 598-605
    • Gordon, G.J.1    Jensen, R.V.2    Hsiao, L.L.3
  • 80
    • 9244228552 scopus 로고    scopus 로고
    • Gene expression profiling for molecular characterization of inflammatory breast cancer and prediction of response to chemotherapy
    • Bertucci F, Finetti P, Rougemont J, et al: Gene expression profiling for molecular characterization of inflammatory breast cancer and prediction of response to chemotherapy. Cancer Res 64:8558-8565, 2004
    • (2004) Cancer Res , vol.64 , pp. 8558-8565
    • Bertucci, F.1    Finetti, P.2    Rougemont, J.3
  • 81
    • 0033536012 scopus 로고    scopus 로고
    • Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
    • Alon U, Barkai N, Notterman DA, et al: Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc Natl Acad Sci USA 96:6745-6750, 1999
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 6745-6750
    • Alon, U.1    Barkai, N.2    Notterman, D.A.3
  • 82
    • 1442308342 scopus 로고    scopus 로고
    • Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters
    • Bertucci F, Salas S, Eysteries S, et al: Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene 23:1377-1391, 2004
    • (2004) Oncogene , vol.23 , pp. 1377-1391
    • Bertucci, F.1    Salas, S.2    Eysteries, S.3
  • 83
    • 2442684455 scopus 로고    scopus 로고
    • Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer
    • Wang Y, Jatkoe T, Zhang Y, et al: Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer. J Clin Oncol 22:1564-1571, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 1564-1571
    • Wang, Y.1    Jatkoe, T.2    Zhang, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.