메뉴 건너뛰기




Volumn 63, Issue 24, 2003, Pages 8791-8812

Gene Expression Profiling-Based Prediction of Response of Colon Carcinoma Cells to 5-Fluorouracil and Camptothecin

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; CAMPTOTHECIN; COMPLEMENTARY DNA; FLUOROURACIL; PROTEIN P53; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

EID: 9144273781     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (196)

References (97)
  • 4
    • 0029644482 scopus 로고
    • Analysis of Colon Cancer Trials (IMPACT) investigators, Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
    • International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators, Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet, 345: 939-944, 1995.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 6
    • 0033377377 scopus 로고    scopus 로고
    • Oxaliplatin: A new therapeutic option in colorectal cancer
    • Cvitkovic, E., and Bekradda, M. Oxaliplatin: a new therapeutic option in colorectal cancer. Semin. Oncol., 26: 647-662, 1999.
    • (1999) Semin. Oncol. , vol.26 , pp. 647-662
    • Cvitkovic, E.1    Bekradda, M.2
  • 9
    • 0038387494 scopus 로고    scopus 로고
    • 5-Fluorouracil: Mechanisms of action and clinical strategies
    • Longley, D. B., Harkin, D. P., and Johnston, P. G. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer, 3: 330-338, 2003.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 10
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman, C. G., Lenz, H. J., Leichman, L., Danenberg, K., Baranda, J., Groshen, S., Boswell, W., Metzger, R., Tan, M., and Danenberg, P. V. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J. Clin. Oncol., 15: 3223-3229, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3    Danenberg, K.4    Baranda, J.5    Groshen, S.6    Boswell, W.7    Metzger, R.8    Tan, M.9    Danenberg, P.V.10
  • 11
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger, R., Danenberg, K., Leichman, C. G., Salonga, D., Schwartz, E. L., Wadler, S., Lenz, H. J., Groshen, S., Leichman, L., and Danenberg, P. V. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin. Cancer Res., 4: 2371-2376, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3    Salonga, D.4    Schwartz, E.L.5    Wadler, S.6    Lenz, H.J.7    Groshen, S.8    Leichman, L.9    Danenberg, P.V.10
  • 13
    • 0028879677 scopus 로고
    • p53 point mutation and survival in colorectal cancer patients
    • Goh, H. S., Yao, J., and Smith, D. R. p53 point mutation and survival in colorectal cancer patients. Cancer Res., 55: 5217-5221, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5217-5221
    • Goh, H.S.1    Yao, J.2    Smith, D.R.3
  • 14
    • 0030035584 scopus 로고    scopus 로고
    • p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas
    • Benhattar, J., Cerottini, J. P., Saraga, E., Metthez, G., and Givel, J. C. p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int. J. Cancer, 69: 190-192, 1996.
    • (1996) Int. J. Cancer , vol.69 , pp. 190-192
    • Benhattar, J.1    Cerottini, J.P.2    Saraga, E.3    Metthez, G.4    Givel, J.C.5
  • 16
    • 0037010411 scopus 로고    scopus 로고
    • DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: A molecular study
    • Barratt, P. L., Seymour, M. T., Stenning, S. P., Georgiades, I., Walker, C., Birbeck, K., and Quirke, P. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study. Lancet, 360: 1381-1391, 2002.
    • (2002) Lancet , vol.360 , pp. 1381-1391
    • Barratt, P.L.1    Seymour, M.T.2    Stenning, S.P.3    Georgiades, I.4    Walker, C.5    Birbeck, K.6    Quirke, P.7
  • 17
    • 0035428087 scopus 로고    scopus 로고
    • Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma
    • Elsaleh, H., and Iacopetta, B. Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma. Clin. Colorectal Cancer, 1: 104-109, 2001.
    • (2001) Clin. Colorectal Cancer , vol.1 , pp. 104-109
    • Elsaleh, H.1    Iacopetta, B.2
  • 18
    • 0034895979 scopus 로고    scopus 로고
    • P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
    • Elsaleh, H., Powell, B., McCaul, K., Grieu, F., Grant, R., Joseph, D., and Iacopetta, B. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin. Cancer Res., 7: 1343-1349, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1343-1349
    • Elsaleh, H.1    Powell, B.2    McCaul, K.3    Grieu, F.4    Grant, R.5    Joseph, D.6    Iacopetta, B.7
  • 20
    • 15644372023 scopus 로고    scopus 로고
    • Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: A frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial
    • Augenlicht, L. H., Wadler, S., Corner, G., Richards, C., Ryan, L., Multani, A. S., Pathak, S., Benson, A., Haller, D., and Heerdt, B. G. Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial. Cancer Res., 57: 1769-1775, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1769-1775
    • Augenlicht, L.H.1    Wadler, S.2    Corner, G.3    Richards, C.4    Ryan, L.5    Multani, A.S.6    Pathak, S.7    Benson, A.8    Haller, D.9    Heerdt, B.G.10
  • 21
    • 0035874884 scopus 로고    scopus 로고
    • c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo
    • Arango, D., Corner, G. A., Wadler, S., Catalano, P. J., and Augenlicht, L. H. c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo. Cancer Res., 61: 4910-4915, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 4910-4915
    • Arango, D.1    Corner, G.A.2    Wadler, S.3    Catalano, P.J.4    Augenlicht, L.H.5
  • 22
    • 0037126303 scopus 로고    scopus 로고
    • cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature (Lond.), 419: 729-734, 2002.
    • (2002) Nature (Lond.) , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massague, J.3
  • 25
    • 0037440051 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    • Allegra, C. J., Paik, S., Colangelo, L. H., Parr, A. L., Kirsch, I., Kim, G., Klein, P. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. 89: 1757-1765, 2003. Johnston, P. G., Wolmark, N., and Wieand, H. S. Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J. Clin. Oncol., 21: 241-250, 2003.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 241-250
    • Johnston, P.G.1    Wolmark, N.2    Wieand, H.S.3
  • 26
    • 0037364351 scopus 로고    scopus 로고
    • Thymidylate synthase protein expression in primary colorectal cancer: Lack of correlation with outcome and response to fluorouracil in metastatic disease sites
    • Johnston, P. G., Benson, A. B., III, Catalano, P., Rao, M. S., O'Dwyer, P. J., and Allegra, C. J. Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites. J. Clin. Oncol., 21: 815-819, 2003.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 815-819
    • Johnston, P.G.1    Benson III, A.B.2    Catalano, P.3    Rao, M.S.4    O'Dwyer, P.J.5    Allegra, C.J.6
  • 27
    • 0036875104 scopus 로고    scopus 로고
    • Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma
    • Berglund, A., Edler, D., Molin, D., Nordlinder, H., Graf, W., and Glimelius, B. Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma. Anticancer Res., 22: 3653-3659, 2002.
    • (2002) Anticancer Res. , vol.22 , pp. 3653-3659
    • Berglund, A.1    Edler, D.2    Molin, D.3    Nordlinder, H.4    Graf, W.5    Glimelius, B.6
  • 28
    • 0031053520 scopus 로고    scopus 로고
    • Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy
    • Findlay, M. P., Cunningham, D., Morgan, G., Clinton, S., Hardcastle, A., and Aherne, G. W. Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy. Br. J. Cancer, 75: 903-909, 1997.
    • (1997) Br. J. Cancer , vol.75 , pp. 903-909
    • Findlay, M.P.1    Cunningham, D.2    Morgan, G.3    Clinton, S.4    Hardcastle, A.5    Aherne, G.W.6
  • 29
    • 0026795489 scopus 로고
    • Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
    • Johnston, P. G., Drake, J. C., Trepel, J., and Allegra, C. J. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res., 52: 4306-4312, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 4306-4312
    • Johnston, P.G.1    Drake, J.C.2    Trepel, J.3    Allegra, C.J.4
  • 30
    • 0031832182 scopus 로고    scopus 로고
    • Thymidylate synthase expression and activity: Relation to S-phase parameters and 5-fluorouracil sensitivity
    • Mirjolet, J. F., Barberi-Heyob, M., Merlin, J. L., Marchal, S., Etienne, M. C., Milano, G., and Bey, P. Thymidylate synthase expression and activity: relation to S-phase parameters and 5-fluorouracil sensitivity. Br. J. Cancer, 78: 62-68, 1998.
    • (1998) Br. J. Cancer , vol.78 , pp. 62-68
    • Mirjolet, J.F.1    Barberi-Heyob, M.2    Merlin, J.L.3    Marchal, S.4    Etienne, M.C.5    Milano, G.6    Bey, P.7
  • 31
    • 0034906625 scopus 로고    scopus 로고
    • Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen
    • Grem, J. L., Danenberg, K. D., Behan, K., Parr, A., Young, L., Danenberg, P. V., Nguyen, D., Drake, J., Monks, A., and Allegra, C. J. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen. Clin. Cancer Res., 7: 999-1009, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 999-1009
    • Grem, J.L.1    Danenberg, K.D.2    Behan, K.3    Parr, A.4    Young, L.5    Danenberg, P.V.6    Nguyen, D.7    Drake, J.8    Monks, A.9    Allegra, C.J.10
  • 33
    • 0029051690 scopus 로고
    • Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil
    • Schwartz, E. L., Baptiste, N., Wadler, S., and Makower, D. Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil. J. Biol. Chem., 270: 19073-19077, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19073-19077
    • Schwartz, E.L.1    Baptiste, N.2    Wadler, S.3    Makower, D.4
  • 34
    • 0032864482 scopus 로고    scopus 로고
    • The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma
    • Saito, H., Tsujitani, S., Oka, S., Kondo, A., Ikeguchi, M., Maeta, M., and Kaibara, N. The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma. Br. J. Cancer, 81: 484-489, 1999.
    • (1999) Br. J. Cancer , vol.81 , pp. 484-489
    • Saito, H.1    Tsujitani, S.2    Oka, S.3    Kondo, A.4    Ikeguchi, M.5    Maeta, M.6    Kaibara, N.7
  • 35
    • 0023550835 scopus 로고
    • Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro
    • Augenlicht, L. H., Wahrman, M. Z., Halsey, H., Anderson, L., Taylor, J., and Lipkin, M. Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro. Cancer Res., 47: 6017-6021, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 6017-6021
    • Augenlicht, L.H.1    Wahrman, M.Z.2    Halsey, H.3    Anderson, L.4    Taylor, J.5    Lipkin, M.6
  • 36
    • 0026339033 scopus 로고
    • Patterns of gene expression that characterize the colonic mucosa in patients at genetic risk for colonic cancer
    • Augenlicht, L. H., Taylor, J., Anderson, L., and Lipkin, M. Patterns of gene expression that characterize the colonic mucosa in patients at genetic risk for colonic cancer. Proc. Natl. Acad. Sci. USA, 88: 3286-3289, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3286-3289
    • Augenlicht, L.H.1    Taylor, J.2    Anderson, L.3    Lipkin, M.4
  • 39
    • 0021163443 scopus 로고
    • Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate
    • Augeron, C., and Laboisse, C. L. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res., 44: 3961-3969, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 3961-3969
    • Augeron, C.1    Laboisse, C.L.2
  • 40
    • 0021910637 scopus 로고
    • A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer
    • Whitehead, R. H., Macrae, F. A., St John, D. J., and Ma, J. A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer, J. Natl. Cancer Inst. (Bethesda), 74: 759-765, 1985.
    • (1985) J. Natl. Cancer Inst. (Bethesda) , vol.74 , pp. 759-765
    • Whitehead, R.H.1    Macrae, F.A.2    St. John, D.J.3    Ma, J.4
  • 48
    • 0034662614 scopus 로고    scopus 로고
    • Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
    • Mariadason, J. M., Corner, G. A., and Augenlicht, L. H. Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res., 60: 4561-4572, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 4561-4572
    • Mariadason, J.M.1    Corner, G.A.2    Augenlicht, L.H.3
  • 54
    • 0013965282 scopus 로고
    • An isotopic assay for thymidylate synthase
    • Roberts, D. An isotopic assay for thymidylate synthase. Biochemistry, 5: 3546-3548, 1966.
    • (1966) Biochemistry , vol.5 , pp. 3546-3548
    • Roberts, D.1
  • 55
    • 0037439694 scopus 로고    scopus 로고
    • Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration
    • Hotchkiss, K. A., Ashton, A. W., Klein, R. S., Lenzi, M. L., Zhu, G. H., and Schwartz, E. L. Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration. Cancer Res., 63: 527-533, 2003.
    • (2003) Cancer Res. , vol.63 , pp. 527-533
    • Hotchkiss, K.A.1    Ashton, A.W.2    Klein, R.S.3    Lenzi, M.L.4    Zhu, G.H.5    Schwartz, E.L.6
  • 57
    • 0017749234 scopus 로고
    • Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum
    • Tibbetts, L. M., Chu, M. Y., Hager, J. C., Dexter, D. L., and Calabresi, P. Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum. Cancer (Phila.), 40: 2651-2659, 1977.
    • (1977) Cancer (Phila.) , vol.40 , pp. 2651-2659
    • Tibbetts, L.M.1    Chu, M.Y.2    Hager, J.C.3    Dexter, D.L.4    Calabresi, P.5
  • 59
    • 0036168343 scopus 로고    scopus 로고
    • An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines
    • Dan, S., Tsunoda, T., Kitahara, O., Yanagawa, R., Zembutsu, H., Katagiri, T., Yamazaki, K., Nakamura, Y., and Yamori, T. An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Res., 62: 1139-1147, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 1139-1147
    • Dan, S.1    Tsunoda, T.2    Kitahara, O.3    Yanagawa, R.4    Zembutsu, H.5    Katagiri, T.6    Yamazaki, K.7    Nakamura, Y.8    Yamori, T.9
  • 60
    • 0027423480 scopus 로고
    • A Phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma
    • Grem, J. L., McAtee, N., Steinberg, S. M., Hamilton, J. M., Murphy, R. F., Drake, J., Chisena, T., Balis, F., Cysyk, R., Arbuck, S. G., et al. A Phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma. Cancer Res., 53: 4828-4836, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4828-4836
    • Grem, J.L.1    McAtee, N.2    Steinberg, S.M.3    Hamilton, J.M.4    Murphy, R.F.5    Drake, J.6    Chisena, T.7    Balis, F.8    Cysyk, R.9    Arbuck, S.G.10
  • 62
    • 0037263812 scopus 로고    scopus 로고
    • MAPPFinder: Using Gene Omology and GenMAPP to create a global gene-expression profile from microarray data
    • Doniger, S. W., Salomonis, N., Dahlquist, K. D., Vranizan, K., Lawlor, S. C., and Conklin, B. R. MAPPFinder: using Gene Omology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol., 4: R7, 2003.
    • (2003) Genome Biol. , vol.4
    • Doniger, S.W.1    Salomonis, N.2    Dahlquist, K.D.3    Vranizan, K.4    Lawlor, S.C.5    Conklin, B.R.6
  • 63
    • 0036578644 scopus 로고    scopus 로고
    • GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
    • Dahlquist, K. D., Salomonis, N., Vranizan, K., Lawlor, S. C., and Conklin, B. R. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat. Genet., 31: 19-20, 2002.
    • (2002) Nat. Genet. , vol.31 , pp. 19-20
    • Dahlquist, K.D.1    Salomonis, N.2    Vranizan, K.3    Lawlor, S.C.4    Conklin, B.R.5
  • 65
    • 0031018610 scopus 로고    scopus 로고
    • Heat shock response: Pathophysiological implications
    • Leppa, S., and Sistonen, L. Heat shock response: pathophysiological implications. Ann. Med., 29: 73-78, 1997.
    • (1997) Ann. Med. , vol.29 , pp. 73-78
    • Leppa, S.1    Sistonen, L.2
  • 66
    • 0031783644 scopus 로고    scopus 로고
    • Expression of differentiation-related genes in colorectal cancer: Possible implications for prognosis
    • van Belzen, N., Dinjens, W. N., Eussen, B. H., and Bosman, F. I. Expression of differentiation-related genes in colorectal cancer: possible implications for prognosis. Histol. Histopathol. 13: 1233-1242, 1998.
    • (1998) Histol. Histopathol. , vol.13 , pp. 1233-1242
    • Van Belzen, N.1    Dinjens, W.N.2    Eussen, B.H.3    Bosman, F.I.4
  • 67
    • 0025743989 scopus 로고
    • Nucleolar protein B23 translocation after deferoxamine treatment in a human leukemia cell line
    • Yung, B. Y., Yang, Y. H., and Bor, A. M. Nucleolar protein B23 translocation after deferoxamine treatment in a human leukemia cell line. Int. J. Cancer, 48: 779-784, 1991.
    • (1991) Int. J. Cancer , vol.48 , pp. 779-784
    • Yung, B.Y.1    Yang, Y.H.2    Bor, A.M.3
  • 69
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
    • Scorrano, L., and Korsmeyer, S. J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun., 304, 437-444, 2003.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , pp. 437-444
    • Scorrano, L.1    Korsmeyer, S.J.2
  • 71
    • 0034939638 scopus 로고    scopus 로고
    • Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells
    • Takechi, T., Koizumi, K., Tsujimoto, H., and Fukushima, M. Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells. Jpn. J. Cancer Res., 92: 696-703, 2001.
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 696-703
    • Takechi, T.1    Koizumi, K.2    Tsujimoto, H.3    Fukushima, M.4
  • 72
    • 0037990003 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: A novel genomic predictor of clinical response to flouropyrimidine-based chemotherapy
    • Cohen, V., Panet-Raymond, V., Sabbaghian, N., Morin, I., Batist, G., and Rozen, R. Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to flouropyrimidine-based chemotherapy. Clin. Cancer Res., 9: 1611-1615, 2003.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1611-1615
    • Cohen, V.1    Panet-Raymond, V.2    Sabbaghian, N.3    Morin, I.4    Batist, G.5    Rozen, R.6
  • 73
    • 0033748796 scopus 로고    scopus 로고
    • p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines
    • Petak, I., Tillman, D. M., and Houghton, J. A. p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines. Clin. Cancer Res., 6: 4432-4441, 2000.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4432-4441
    • Petak, I.1    Tillman, D.M.2    Houghton, J.A.3
  • 75
    • 0033778049 scopus 로고    scopus 로고
    • Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
    • Hemminki, A., Mecklin, J. P., Jarvinen, H., Aaltonen, L. A., and Joensuu, H. Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology, 119: 921-928, 2000.
    • (2000) Gastroenterology , vol.119 , pp. 921-928
    • Hemminki, A.1    Mecklin, J.P.2    Jarvinen, H.3    Aaltonen, L.A.4    Joensuu, H.5
  • 77
    • 0034690610 scopus 로고    scopus 로고
    • Association of tumor site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
    • Elsaleh, H., Joseph, D., Grieu, F., Zeps, N., Spry, N., and Iacopetta, B. Association of tumor site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer. Lancet, 355: 1745-1750, 2000.
    • (2000) Lancet , vol.355 , pp. 1745-1750
    • Elsaleh, H.1    Joseph, D.2    Grieu, F.3    Zeps, N.4    Spry, N.5    Iacopetta, B.6
  • 81
    • 0029962567 scopus 로고    scopus 로고
    • Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
    • Yang, B., Eshleman, J. R., Berger, N. A., and Markowitz, S. D. Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clin. Cancer Res., 2: 1649-1657, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1649-1657
    • Yang, B.1    Eshleman, J.R.2    Berger, N.A.3    Markowitz, S.D.4
  • 82
    • 0035392965 scopus 로고    scopus 로고
    • Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses
    • Meyers, M., Wagner, M. W., Hwang, H. S., Kinsella, T. J., and Boothman, D. A. Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. Cancer Res., 61: 5193-5201, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 5193-5201
    • Meyers, M.1    Wagner, M.W.2    Hwang, H.S.3    Kinsella, T.J.4    Boothman, D.A.5
  • 83
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia: A key regulatory factor in tumor growth
    • Harris, A. L. Hypoxia: a key regulatory factor in tumor growth. Nat. Rev. Cancer, 2: 38-47, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 85
    • 0026003123 scopus 로고
    • Hypoxia-induced drug resistance: Comparison to P-glycoprotein-associated drug resistance
    • Sakata, K., Kwok, T. T., Murphy, B. J., Laderoute, K. R., Gordon, G. R., and Sutherland, R. M. Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance. Br. J. Cancer, 64: 809-814, 1991.
    • (1991) Br. J. Cancer , vol.64 , pp. 809-814
    • Sakata, K.1    Kwok, T.T.2    Murphy, B.J.3    Laderoute, K.R.4    Gordon, G.R.5    Sutherland, R.M.6
  • 86
    • 0033808725 scopus 로고    scopus 로고
    • Oxygen regulation of gene expression: A study in opposites
    • D'Angio, C. T., and Finkelstein, J. N. Oxygen regulation of gene expression: a study in opposites. Mol. Genet. Metab., 71: 371-380, 2000.
    • (2000) Mol. Genet. Metab. , vol.71 , pp. 371-380
    • D'Angio, C.T.1    Finkelstein, J.N.2
  • 87
    • 0030946752 scopus 로고    scopus 로고
    • Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products
    • Djelloul, S., Forgue-Lafitte, M. E., Hermelin, B., Mareel, M., Bruyneel, E., Baldi, A., Giordano, A., Chastre, E., and Gespach, C. Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products. FEBS Lett., 406: 234-242, 1997.
    • (1997) FEBS Lett. , vol.406 , pp. 234-242
    • Djelloul, S.1    Forgue-Lafitte, M.E.2    Hermelin, B.3    Mareel, M.4    Bruyneel, E.5    Baldi, A.6    Giordano, A.7    Chastre, E.8    Gespach, C.9
  • 88
    • 0033621170 scopus 로고    scopus 로고
    • Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: The predominant role of hMLH1
    • Wheeler, J. M., Beck, N. E., Kim, H. C., Tomlinson, I. P., Mortensen, N. J., and Bodmer, W. F. Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1. Proc. Natl. Acad. Sci. USA, 96: 10296-10301, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10296-10301
    • Wheeler, J.M.1    Beck, N.E.2    Kim, H.C.3    Tomlinson, I.P.4    Mortensen, N.J.5    Bodmer, W.F.6
  • 90
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., Jr., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend, S.11    Fornace Jr., A.J.12    Kohn, K.W.13
  • 91
    • 0030475069 scopus 로고    scopus 로고
    • Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines
    • Cottu, P. H., Muzeau, F., Estreicher, A., Flejou, J. F., Iggo, R., Thomas, G., and Hamelin, R. Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines. Oncogene, 13: 2727-2730, 1996.
    • (1996) Oncogene , vol.13 , pp. 2727-2730
    • Cottu, P.H.1    Muzeau, F.2    Estreicher, A.3    Flejou, J.F.4    Iggo, R.5    Thomas, G.6    Hamelin, R.7
  • 93
    • 0029841372 scopus 로고    scopus 로고
    • DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells
    • Matsui, S. I., Arredondo, M. A., Wrzosek, C., and Rustum, Y. M. DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells. Cancer Res., 56: 4715-4723, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4715-4723
    • Matsui, S.I.1    Arredondo, M.A.2    Wrzosek, C.3    Rustum, Y.M.4
  • 94
    • 0028785603 scopus 로고
    • Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
    • Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548-5550, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5548-5550
    • Parsons, R.1    Myeroff, L.L.2    Liu, B.3    Willson, J.K.4    Markowitz, S.D.5    Kinzler, K.W.6    Vogelstein, B.7
  • 96
    • 0033135049 scopus 로고    scopus 로고
    • Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression
    • Deng, G., Chen, A., Hong, J., Chae, H. S., and Kim, Y. S. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res., 59: 2029-2033, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2029-2033
    • Deng, G.1    Chen, A.2    Hong, J.3    Chae, H.S.4    Kim, Y.S.5
  • 97
    • 0035899332 scopus 로고    scopus 로고
    • Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
    • Gayet, J., Zhou, X. P., Duval, A., Rolland, S., Hoang, J. M., Cottu, P., and Hamelin, R. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene, 20: 5025-5032, 2001.
    • (2001) Oncogene , vol.20 , pp. 5025-5032
    • Gayet, J.1    Zhou, X.P.2    Duval, A.3    Rolland, S.4    Hoang, J.M.5    Cottu, P.6    Hamelin, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.