-
1
-
-
0025060806
-
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
-
Moertel, C. G., Fleming, T. R., Macdonald, J. S., Haller, D. G., Laurie, J. A., Goodman, P. J., Ungerleider, J. S., Emerson, W. A., Tormey, D. C., Glick, J. H., et al. Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N. Engl. J. Med. 322: 352-358, 1990.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 352-358
-
-
Moertel, C.G.1
Fleming, T.R.2
Macdonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Goodman, P.J.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
-
2
-
-
0028956045
-
Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
-
Moertel, C. G., Fleming, T. R., Macdonald, J. S., Haller, D. G., Laurie, J. A., Tangen, C. M., Ungerleider, J. S., Emerson, W. A., Tormey, D. C., Glick, J. H., et al. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann. Intern. Med., 122: 321-326, 1995.
-
(1995)
Ann. Intern. Med.
, vol.122
, pp. 321-326
-
-
Moertel, C.G.1
Fleming, T.R.2
Macdonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Tangen, C.M.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
-
3
-
-
0028835122
-
Intergroup study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes' B2 colon cancer
-
Moertel, C. G., Fleming, T. R., Macdonald, J. S., Haller, D. G., Laurie, J. A., Tangen, C. M., Ungerleider, J. S., Emerson, W. A., Tormey, D. C., Glick, J. H., et al. Intergroup study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes' B2 colon cancer. J. Clin. Oncol., 13: 2936-2943, 1995.
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 2936-2943
-
-
Moertel, C.G.1
Fleming, T.R.2
Macdonald, J.S.3
Haller, D.G.4
Laurie, J.A.5
Tangen, C.M.6
Ungerleider, J.S.7
Emerson, W.A.8
Tormey, D.C.9
Glick, J.H.10
-
4
-
-
0029644482
-
Analysis of Colon Cancer Trials (IMPACT) investigators, Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
-
International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators, Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet, 345: 939-944, 1995.
-
(1995)
Lancet
, vol.345
, pp. 939-944
-
-
-
5
-
-
0029919598
-
Irinotecan is an active agent in untreated patients with metastatic colorectal cancer
-
Conti, J. A., Kemeny, N. E., Saltz, L. B., Huang, Y., Tong, W. P., Chou, T. C., Sun, M., Pulliam, S., and Gonzalez, C. Irinotecan is an active agent in untreated patients with metastatic colorectal cancer. J. Clin. Oncol., 14: 709-715, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 709-715
-
-
Conti, J.A.1
Kemeny, N.E.2
Saltz, L.B.3
Huang, Y.4
Tong, W.P.5
Chou, T.C.6
Sun, M.7
Pulliam, S.8
Gonzalez, C.9
-
6
-
-
0033377377
-
Oxaliplatin: A new therapeutic option in colorectal cancer
-
Cvitkovic, E., and Bekradda, M. Oxaliplatin: a new therapeutic option in colorectal cancer. Semin. Oncol., 26: 647-662, 1999.
-
(1999)
Semin. Oncol.
, vol.26
, pp. 647-662
-
-
Cvitkovic, E.1
Bekradda, M.2
-
7
-
-
0030888321
-
Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer
-
de Gramont, A., Vignoud, J., Tournigand, C., Louvet, C., Andre, T., Varette, C., Raymond, E., Moreau, S., Le Bail, N., and Krulik, M. Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer. Eur. J. Cancer, 33: 214-219, 1997.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 214-219
-
-
De Gramont, A.1
Vignoud, J.2
Tournigand, C.3
Louvet, C.4
Andre, T.5
Varette, C.6
Raymond, E.7
Moreau, S.8
Le Bail, N.9
Krulik, M.10
-
8
-
-
0012797224
-
Two consecutive Phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines
-
Machover, D., Diaz-Rubio, E., de Gramont, A., Schilf, A., Gastiaburu, J. J., Brienza, S., Itzhaki, M., Metzger, G., N'Daw, D., Vignoud, J., Abad, A., Francois, E., Gamelin, E., Marty, M., Sastre, J., Seitz, J. F., and Ychou, M. Two consecutive Phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines. Ann. Oncol., 7: 95-98, 1996.
-
(1996)
Ann. Oncol.
, vol.7
, pp. 95-98
-
-
Machover, D.1
Diaz-Rubio, E.2
De Gramont, A.3
Schilf, A.4
Gastiaburu, J.J.5
Brienza, S.6
Itzhaki, M.7
Metzger, G.8
N'Daw, D.9
Vignoud, J.10
Abad, A.11
Francois, E.12
Gamelin, E.13
Marty, M.14
Sastre, J.15
Seitz, J.F.16
Ychou, M.17
-
9
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
Longley, D. B., Harkin, D. P., and Johnston, P. G. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer, 3: 330-338, 2003.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
10
-
-
0030883708
-
Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
-
Leichman, C. G., Lenz, H. J., Leichman, L., Danenberg, K., Baranda, J., Groshen, S., Boswell, W., Metzger, R., Tan, M., and Danenberg, P. V. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J. Clin. Oncol., 15: 3223-3229, 1997.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 3223-3229
-
-
Leichman, C.G.1
Lenz, H.J.2
Leichman, L.3
Danenberg, K.4
Baranda, J.5
Groshen, S.6
Boswell, W.7
Metzger, R.8
Tan, M.9
Danenberg, P.V.10
-
11
-
-
0031722179
-
High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
-
Metzger, R., Danenberg, K., Leichman, C. G., Salonga, D., Schwartz, E. L., Wadler, S., Lenz, H. J., Groshen, S., Leichman, L., and Danenberg, P. V. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin. Cancer Res., 4: 2371-2376, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2371-2376
-
-
Metzger, R.1
Danenberg, K.2
Leichman, C.G.3
Salonga, D.4
Schwartz, E.L.5
Wadler, S.6
Lenz, H.J.7
Groshen, S.8
Leichman, L.9
Danenberg, P.V.10
-
12
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
-
Salonga, D., Danenberg, K. D., Johnson, M., Metzger, R., Groshen, S., Tsao-Wei, D. D., Lenz, H. J., Leichman, C. G., Leichman, L., Diasio, R. B., and Danenberg, P. V. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin. Cancer Res., 6: 1322-1327, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
Lenz, H.J.7
Leichman, C.G.8
Leichman, L.9
Diasio, R.B.10
Danenberg, P.V.11
-
13
-
-
0028879677
-
p53 point mutation and survival in colorectal cancer patients
-
Goh, H. S., Yao, J., and Smith, D. R. p53 point mutation and survival in colorectal cancer patients. Cancer Res., 55: 5217-5221, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 5217-5221
-
-
Goh, H.S.1
Yao, J.2
Smith, D.R.3
-
14
-
-
0030035584
-
p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas
-
Benhattar, J., Cerottini, J. P., Saraga, E., Metthez, G., and Givel, J. C. p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int. J. Cancer, 69: 190-192, 1996.
-
(1996)
Int. J. Cancer
, vol.69
, pp. 190-192
-
-
Benhattar, J.1
Cerottini, J.P.2
Saraga, E.3
Metthez, G.4
Givel, J.C.5
-
15
-
-
0032521205
-
Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study
-
Ahnen, D. J., Feigl, P., Quan, G., Fenoglio-Preiser, C., Lovato, L. C., Bunn, P. A., Jr., Stemmerman, G., Wells, J. D., Macdonald, J. S., and Meyskens, F. L., Jr. Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study. Cancer Res., 58: 1149-1158, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 1149-1158
-
-
Ahnen, D.J.1
Feigl, P.2
Quan, G.3
Fenoglio-Preiser, C.4
Lovato, L.C.5
Bunn Jr., P.A.6
Stemmerman, G.7
Wells, J.D.8
Macdonald, J.S.9
Meyskens Jr., F.L.10
-
16
-
-
0037010411
-
DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: A molecular study
-
Barratt, P. L., Seymour, M. T., Stenning, S. P., Georgiades, I., Walker, C., Birbeck, K., and Quirke, P. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study. Lancet, 360: 1381-1391, 2002.
-
(2002)
Lancet
, vol.360
, pp. 1381-1391
-
-
Barratt, P.L.1
Seymour, M.T.2
Stenning, S.P.3
Georgiades, I.4
Walker, C.5
Birbeck, K.6
Quirke, P.7
-
17
-
-
0035428087
-
Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma
-
Elsaleh, H., and Iacopetta, B. Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma. Clin. Colorectal Cancer, 1: 104-109, 2001.
-
(2001)
Clin. Colorectal Cancer
, vol.1
, pp. 104-109
-
-
Elsaleh, H.1
Iacopetta, B.2
-
18
-
-
0034895979
-
P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
-
Elsaleh, H., Powell, B., McCaul, K., Grieu, F., Grant, R., Joseph, D., and Iacopetta, B. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin. Cancer Res., 7: 1343-1349, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1343-1349
-
-
Elsaleh, H.1
Powell, B.2
McCaul, K.3
Grieu, F.4
Grant, R.5
Joseph, D.6
Iacopetta, B.7
-
19
-
-
0036533524
-
L in addition to Bax and p53 status
-
L in addition to Bax and p53 status. Int. J. Cancer, 98: 498-504, 2002.
-
(2002)
Int. J. Cancer
, vol.98
, pp. 498-504
-
-
Violette, S.1
Poulain, L.2
Dussaulx, E.3
Pepin, D.4
Faussat, A.M.5
Chambaz, J.6
Lacorte, J.M.7
Staedel, C.8
Lesuffleur, T.9
-
20
-
-
15644372023
-
Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: A frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial
-
Augenlicht, L. H., Wadler, S., Corner, G., Richards, C., Ryan, L., Multani, A. S., Pathak, S., Benson, A., Haller, D., and Heerdt, B. G. Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial. Cancer Res., 57: 1769-1775, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 1769-1775
-
-
Augenlicht, L.H.1
Wadler, S.2
Corner, G.3
Richards, C.4
Ryan, L.5
Multani, A.S.6
Pathak, S.7
Benson, A.8
Haller, D.9
Heerdt, B.G.10
-
21
-
-
0035874884
-
c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo
-
Arango, D., Corner, G. A., Wadler, S., Catalano, P. J., and Augenlicht, L. H. c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo. Cancer Res., 61: 4910-4915, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 4910-4915
-
-
Arango, D.1
Corner, G.A.2
Wadler, S.3
Catalano, P.J.4
Augenlicht, L.H.5
-
22
-
-
0037126303
-
cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature (Lond.), 419: 729-734, 2002.
-
(2002)
Nature (Lond.)
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
23
-
-
0344009714
-
c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
-
Arango, D., Mariadason, J. M., Wilson, A. J., Yang, W., Corner, G. A., Nicholas, C., Aranes, M. J., and Augenlicht, L. H. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. Br. J. Cancer, 89: 1757-1765, 2003.
-
(2003)
Br. J. Cancer
, vol.89
, pp. 1757-1765
-
-
Arango, D.1
Mariadason, J.M.2
Wilson, A.J.3
Yang, W.4
Corner, G.A.5
Nicholas, C.6
Aranes, M.J.7
Augenlicht, L.H.8
-
24
-
-
0037440051
-
-
Allegra, C. J., Paik, S., Colangelo, L. H., Parr, A. L., Kirsch, I., Kim, G., Klein, P. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. 89: 1757-1765, 2003. Johnston, P. G., Wolmark, N., and Wieand, H. S. Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J. Clin. Oncol., 21: 241-250, 2003.
-
(2003)
c-Myc Overexpression Sensitises Colon Cancer Cells to Camptothecin-Induced Apoptosis
, vol.89
, pp. 1757-1765
-
-
Allegra, C.J.1
Paik, S.2
Colangelo, L.H.3
Parr, A.L.4
Kirsch, I.5
Kim, G.6
Klein, P.7
-
25
-
-
0037440051
-
Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
-
Allegra, C. J., Paik, S., Colangelo, L. H., Parr, A. L., Kirsch, I., Kim, G., Klein, P. c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. 89: 1757-1765, 2003. Johnston, P. G., Wolmark, N., and Wieand, H. S. Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J. Clin. Oncol., 21: 241-250, 2003.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 241-250
-
-
Johnston, P.G.1
Wolmark, N.2
Wieand, H.S.3
-
26
-
-
0037364351
-
Thymidylate synthase protein expression in primary colorectal cancer: Lack of correlation with outcome and response to fluorouracil in metastatic disease sites
-
Johnston, P. G., Benson, A. B., III, Catalano, P., Rao, M. S., O'Dwyer, P. J., and Allegra, C. J. Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites. J. Clin. Oncol., 21: 815-819, 2003.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 815-819
-
-
Johnston, P.G.1
Benson III, A.B.2
Catalano, P.3
Rao, M.S.4
O'Dwyer, P.J.5
Allegra, C.J.6
-
27
-
-
0036875104
-
Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma
-
Berglund, A., Edler, D., Molin, D., Nordlinder, H., Graf, W., and Glimelius, B. Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma. Anticancer Res., 22: 3653-3659, 2002.
-
(2002)
Anticancer Res.
, vol.22
, pp. 3653-3659
-
-
Berglund, A.1
Edler, D.2
Molin, D.3
Nordlinder, H.4
Graf, W.5
Glimelius, B.6
-
28
-
-
0031053520
-
Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy
-
Findlay, M. P., Cunningham, D., Morgan, G., Clinton, S., Hardcastle, A., and Aherne, G. W. Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy. Br. J. Cancer, 75: 903-909, 1997.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 903-909
-
-
Findlay, M.P.1
Cunningham, D.2
Morgan, G.3
Clinton, S.4
Hardcastle, A.5
Aherne, G.W.6
-
29
-
-
0026795489
-
Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
-
Johnston, P. G., Drake, J. C., Trepel, J., and Allegra, C. J. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res., 52: 4306-4312, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 4306-4312
-
-
Johnston, P.G.1
Drake, J.C.2
Trepel, J.3
Allegra, C.J.4
-
30
-
-
0031832182
-
Thymidylate synthase expression and activity: Relation to S-phase parameters and 5-fluorouracil sensitivity
-
Mirjolet, J. F., Barberi-Heyob, M., Merlin, J. L., Marchal, S., Etienne, M. C., Milano, G., and Bey, P. Thymidylate synthase expression and activity: relation to S-phase parameters and 5-fluorouracil sensitivity. Br. J. Cancer, 78: 62-68, 1998.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 62-68
-
-
Mirjolet, J.F.1
Barberi-Heyob, M.2
Merlin, J.L.3
Marchal, S.4
Etienne, M.C.5
Milano, G.6
Bey, P.7
-
31
-
-
0034906625
-
Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen
-
Grem, J. L., Danenberg, K. D., Behan, K., Parr, A., Young, L., Danenberg, P. V., Nguyen, D., Drake, J., Monks, A., and Allegra, C. J. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen. Clin. Cancer Res., 7: 999-1009, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 999-1009
-
-
Grem, J.L.1
Danenberg, K.D.2
Behan, K.3
Parr, A.4
Young, L.5
Danenberg, P.V.6
Nguyen, D.7
Drake, J.8
Monks, A.9
Allegra, C.J.10
-
32
-
-
0037081081
-
Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs
-
Zembutsu, H., Ohnishi, Y., Tsunoda, T., Furukawa, Y., Katagiri, T., Ueyama, Y., Tamaoki, N., Nomura, T., Kitahara, O., Yanagawa, R., Hirata, K., and Nakamura, Y. Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs. Cancer Res., 62: 518-527, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 518-527
-
-
Zembutsu, H.1
Ohnishi, Y.2
Tsunoda, T.3
Furukawa, Y.4
Katagiri, T.5
Ueyama, Y.6
Tamaoki, N.7
Nomura, T.8
Kitahara, O.9
Yanagawa, R.10
Hirata, K.11
Nakamura, Y.12
-
33
-
-
0029051690
-
Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil
-
Schwartz, E. L., Baptiste, N., Wadler, S., and Makower, D. Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil. J. Biol. Chem., 270: 19073-19077, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19073-19077
-
-
Schwartz, E.L.1
Baptiste, N.2
Wadler, S.3
Makower, D.4
-
34
-
-
0032864482
-
The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma
-
Saito, H., Tsujitani, S., Oka, S., Kondo, A., Ikeguchi, M., Maeta, M., and Kaibara, N. The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma. Br. J. Cancer, 81: 484-489, 1999.
-
(1999)
Br. J. Cancer
, vol.81
, pp. 484-489
-
-
Saito, H.1
Tsujitani, S.2
Oka, S.3
Kondo, A.4
Ikeguchi, M.5
Maeta, M.6
Kaibara, N.7
-
35
-
-
0023550835
-
Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro
-
Augenlicht, L. H., Wahrman, M. Z., Halsey, H., Anderson, L., Taylor, J., and Lipkin, M. Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro. Cancer Res., 47: 6017-6021, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 6017-6021
-
-
Augenlicht, L.H.1
Wahrman, M.Z.2
Halsey, H.3
Anderson, L.4
Taylor, J.5
Lipkin, M.6
-
36
-
-
0026339033
-
Patterns of gene expression that characterize the colonic mucosa in patients at genetic risk for colonic cancer
-
Augenlicht, L. H., Taylor, J., Anderson, L., and Lipkin, M. Patterns of gene expression that characterize the colonic mucosa in patients at genetic risk for colonic cancer. Proc. Natl. Acad. Sci. USA, 88: 3286-3289, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3286-3289
-
-
Augenlicht, L.H.1
Taylor, J.2
Anderson, L.3
Lipkin, M.4
-
37
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., Bloomfield, C. D., and Lander, E. S. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science (Wash. DC), 286: 531-537, 1999.
-
(1999)
Science (Wash. DC)
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
Coller, H.7
Loh, M.L.8
Downing, J.R.9
Caligiuri, M.A.10
Bloomfield, C.D.11
Lander, E.S.12
-
38
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy, S. L., Tamayo, P., Gaasenbeek, M., Sturla, L. M., Angelo, M., McLaughlin, M. E., Kim, J. Y., Goumnerova, L. C., Black, P. M., Lau, C., Allen, J. C., Zagzag, D., Olson, J. M., Curran, T., Wetmore, C., Biegel, J. A., Poggio, T., Mukherjee, S., Rifkin, R., Califano, A., Stolovitzky, G., Louis, D. N., Mesirov, J. P., Lander, E. S., and Golub, T. R. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (Lond.), 415: 436-442, 2002.
-
(2002)
Nature (Lond.)
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
Sturla, L.M.4
Angelo, M.5
McLaughlin, M.E.6
Kim, J.Y.7
Goumnerova, L.C.8
Black, P.M.9
Lau, C.10
Allen, J.C.11
Zagzag, D.12
Olson, J.M.13
Curran, T.14
Wetmore, C.15
Biegel, J.A.16
Poggio, T.17
Mukherjee, S.18
Rifkin, R.19
Califano, A.20
Stolovitzky, G.21
Louis, D.N.22
Mesirov, J.P.23
Lander, E.S.24
Golub, T.R.25
more..
-
39
-
-
0021163443
-
Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate
-
Augeron, C., and Laboisse, C. L. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res., 44: 3961-3969, 1984.
-
(1984)
Cancer Res.
, vol.44
, pp. 3961-3969
-
-
Augeron, C.1
Laboisse, C.L.2
-
40
-
-
0021910637
-
A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer
-
Whitehead, R. H., Macrae, F. A., St John, D. J., and Ma, J. A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer, J. Natl. Cancer Inst. (Bethesda), 74: 759-765, 1985.
-
(1985)
J. Natl. Cancer Inst. (Bethesda)
, vol.74
, pp. 759-765
-
-
Whitehead, R.H.1
Macrae, F.A.2
St. John, D.J.3
Ma, J.4
-
41
-
-
0027076306
-
Expression of MUC1 and MUC2 mucins by human tumor cell lines
-
Devine, P. L., Birrell, G. W., Whitehead, R. H., Harada, H., Xing, P. X., and McKenzie, I. F. Expression of MUC1 and MUC2 mucins by human tumor cell lines. Tumour Biol., 13: 268-277, 1992.
-
(1992)
Tumour Biol.
, vol.13
, pp. 268-277
-
-
Devine, P.L.1
Birrell, G.W.2
Whitehead, R.H.3
Harada, H.4
Xing, P.X.5
McKenzie, I.F.6
-
42
-
-
0023802002
-
Cell culture of the mucinous variant of human colorectal carcinoma
-
Tibbetts, L. M., Chu, M. Y., Vezeridis, M. P., Miller, P. G., Tibbetts, L. L., Poisson, M. H., Camara, P. D., and Calabresi, P. Cell culture of the mucinous variant of human colorectal carcinoma. Cancer Res., 48: 3751-3759, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 3751-3759
-
-
Tibbetts, L.M.1
Chu, M.Y.2
Vezeridis, M.P.3
Miller, P.G.4
Tibbetts, L.L.5
Poisson, M.H.6
Camara, P.D.7
Calabresi, P.8
-
43
-
-
0025894713
-
p53 mutations in human cancers
-
Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. p53 mutations in human cancers. Science (Wash. DC), 253: 49-53, 1991.
-
(1991)
Science (Wash. DC)
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
44
-
-
0030058617
-
The p53 gene in breast cancer: Prognostic value of complementary DNA sequencing versus immunohistochemistry
-
Sjogren, S., Inganas, M., Norberg, T., Lindgren, A., Nordgren, H., Holmberg, L., and Bergh, J. The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry. J. Natl. Cancer Inst. (Bethesda), 88: 173-182, 1996.
-
(1996)
J. Natl. Cancer Inst. (Bethesda)
, vol.88
, pp. 173-182
-
-
Sjogren, S.1
Inganas, M.2
Norberg, T.3
Lindgren, A.4
Nordgren, H.5
Holmberg, L.6
Bergh, J.7
-
45
-
-
0035361301
-
Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)
-
Loukola, A., Eklin, K., Laiho, P., Salovaara, R., Kristo, P., Jarvinen, H., Mecklin, J. P., Launonen, V., and Aaltonen, L. A. Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res., 61: 4545-4549, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 4545-4549
-
-
Loukola, A.1
Eklin, K.2
Laiho, P.3
Salovaara, R.4
Kristo, P.5
Jarvinen, H.6
Mecklin, J.P.7
Launonen, V.8
Aaltonen, L.A.9
-
46
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., et al. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer Inst. (Bethesda), 83: 757-766, 1991.
-
(1991)
J. Natl. Cancer Inst. (Bethesda)
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
Shoemaker, R.4
Paull, K.5
Vistica, D.6
Hose, C.7
Langley, J.8
Cronise, P.9
Vaigro-Wolff, A.10
-
47
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahon, J., Vistica, D., Warren, J. T., Bokesch, H., Kenney, S., and Boyd, M. R. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. (Bethesda), 82: 1107-1112, 1990.
-
(1990)
J. Natl. Cancer Inst. (Bethesda)
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
48
-
-
0034662614
-
Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
-
Mariadason, J. M., Corner, G. A., and Augenlicht, L. H. Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res., 60: 4561-4572, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 4561-4572
-
-
Mariadason, J.M.1
Corner, G.A.2
Augenlicht, L.H.3
-
49
-
-
0037102193
-
A gene expression profile that defines colon cell maturation in vitro
-
Mariadason, J. M., Arango, D., Corner, G. A., Aranes, M., Hotchkiss, K., A., Yang, W., and Augenlicht, L. H. A gene expression profile that defines colon cell maturation in vitro. Cancer Res., 62: 4791-4804, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 4791-4804
-
-
Mariadason, J.M.1
Arango, D.2
Corner, G.A.3
Aranes, M.4
Hotchkiss, K.5
Yang, W.6
Augenlicht, L.H.7
-
50
-
-
0032608229
-
Making and reading microarrays
-
Cheung, V. G., Morley, M., Aguilar, F., Massimi, A., Kucherlapati, R., and Childs, G. Making and reading microarrays. Nat. Genet., 21: 15-19, 1999.
-
(1999)
Nat. Genet.
, vol.21
, pp. 15-19
-
-
Cheung, V.G.1
Morley, M.2
Aguilar, F.3
Massimi, A.4
Kucherlapati, R.5
Childs, G.6
-
51
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
Eisen, M. B., Spellman, P. T., Brown, P. O., and Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA. 95: 14863-14868, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
Botstein, D.4
-
52
-
-
0035252592
-
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
-
Muller, H., Bracken, A. P., Vernell, R., Moroni, M. C., Christians, F., Grassilli, E., Prosperini, E., Vigo, E., Oliner, J. D., and Helin, K. E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev., 15: 267-285, 2001.
-
(2001)
Genes Dev.
, vol.15
, pp. 267-285
-
-
Muller, H.1
Bracken, A.P.2
Vernell, R.3
Moroni, M.C.4
Christians, F.5
Grassilli, E.6
Prosperini, E.7
Vigo, E.8
Oliner, J.D.9
Helin, K.10
-
54
-
-
0013965282
-
An isotopic assay for thymidylate synthase
-
Roberts, D. An isotopic assay for thymidylate synthase. Biochemistry, 5: 3546-3548, 1966.
-
(1966)
Biochemistry
, vol.5
, pp. 3546-3548
-
-
Roberts, D.1
-
55
-
-
0037439694
-
Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration
-
Hotchkiss, K. A., Ashton, A. W., Klein, R. S., Lenzi, M. L., Zhu, G. H., and Schwartz, E. L. Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration. Cancer Res., 63: 527-533, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 527-533
-
-
Hotchkiss, K.A.1
Ashton, A.W.2
Klein, R.S.3
Lenzi, M.L.4
Zhu, G.H.5
Schwartz, E.L.6
-
56
-
-
0141705418
-
TR3/Nur77 in colon cancer cell apoptosis
-
Wilson, A. J., Arango, D., Mariadason, J. M., Heerdt, B. G., and Augenlicht, L. H. TR3/Nur77 in colon cancer cell apoptosis. Cancer Res., 63: 5401-5407, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 5401-5407
-
-
Wilson, A.J.1
Arango, D.2
Mariadason, J.M.3
Heerdt, B.G.4
Augenlicht, L.H.5
-
57
-
-
0017749234
-
Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum
-
Tibbetts, L. M., Chu, M. Y., Hager, J. C., Dexter, D. L., and Calabresi, P. Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum. Cancer (Phila.), 40: 2651-2659, 1977.
-
(1977)
Cancer (Phila.)
, vol.40
, pp. 2651-2659
-
-
Tibbetts, L.M.1
Chu, M.Y.2
Hager, J.C.3
Dexter, D.L.4
Calabresi, P.5
-
58
-
-
0034050902
-
Systematic variation in gene expression patterns in human cancer cell lines
-
Ross, D. T., Scherf, U., Eisen, M. B., Perou, C. M., Rees, C., Spellman, P., Iyer, V., Jeffrey, S. S., Van de Rijn, M., Waltham, M., Pergamenschikov, A., Lee, J. C., Lashkari, D., Shalon, D., Myers, T. G., Weinstein, J. N., Botstein, D., and Brown, P. O. Systematic variation in gene expression patterns in human cancer cell lines. Nat. Genet., 24: 227-235, 2000.
-
(2000)
Nat. Genet.
, vol.24
, pp. 227-235
-
-
Ross, D.T.1
Scherf, U.2
Eisen, M.B.3
Perou, C.M.4
Rees, C.5
Spellman, P.6
Iyer, V.7
Jeffrey, S.S.8
Van De Rijn, M.9
Waltham, M.10
Pergamenschikov, A.11
Lee, J.C.12
Lashkari, D.13
Shalon, D.14
Myers, T.G.15
Weinstein, J.N.16
Botstein, D.17
Brown, P.O.18
-
59
-
-
0036168343
-
An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines
-
Dan, S., Tsunoda, T., Kitahara, O., Yanagawa, R., Zembutsu, H., Katagiri, T., Yamazaki, K., Nakamura, Y., and Yamori, T. An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Res., 62: 1139-1147, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 1139-1147
-
-
Dan, S.1
Tsunoda, T.2
Kitahara, O.3
Yanagawa, R.4
Zembutsu, H.5
Katagiri, T.6
Yamazaki, K.7
Nakamura, Y.8
Yamori, T.9
-
60
-
-
0027423480
-
A Phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma
-
Grem, J. L., McAtee, N., Steinberg, S. M., Hamilton, J. M., Murphy, R. F., Drake, J., Chisena, T., Balis, F., Cysyk, R., Arbuck, S. G., et al. A Phase I study of continuous infusion 5-fluorouracil plus calcium leucovorin in combination with N-(phosphonacetyl)-L-aspartate in metastatic gastrointestinal adenocarcinoma. Cancer Res., 53: 4828-4836, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4828-4836
-
-
Grem, J.L.1
McAtee, N.2
Steinberg, S.M.3
Hamilton, J.M.4
Murphy, R.F.5
Drake, J.6
Chisena, T.7
Balis, F.8
Cysyk, R.9
Arbuck, S.G.10
-
61
-
-
0025356873
-
Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion
-
Remick, S. C., Grem, J. L., Fischer, P. H., Tutsch, K. D., Alberti, D. B., Nieting, L. M., Tombes, M. B., Bruggink, J., Willson, J. K., and Trump, D. L. Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion. Cancer Res., 50: 2667-2672, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 2667-2672
-
-
Remick, S.C.1
Grem, J.L.2
Fischer, P.H.3
Tutsch, K.D.4
Alberti, D.B.5
Nieting, L.M.6
Tombes, M.B.7
Bruggink, J.8
Willson, J.K.9
Trump, D.L.10
-
62
-
-
0037263812
-
MAPPFinder: Using Gene Omology and GenMAPP to create a global gene-expression profile from microarray data
-
Doniger, S. W., Salomonis, N., Dahlquist, K. D., Vranizan, K., Lawlor, S. C., and Conklin, B. R. MAPPFinder: using Gene Omology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol., 4: R7, 2003.
-
(2003)
Genome Biol.
, vol.4
-
-
Doniger, S.W.1
Salomonis, N.2
Dahlquist, K.D.3
Vranizan, K.4
Lawlor, S.C.5
Conklin, B.R.6
-
63
-
-
0036578644
-
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
-
Dahlquist, K. D., Salomonis, N., Vranizan, K., Lawlor, S. C., and Conklin, B. R. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat. Genet., 31: 19-20, 2002.
-
(2002)
Nat. Genet.
, vol.31
, pp. 19-20
-
-
Dahlquist, K.D.1
Salomonis, N.2
Vranizan, K.3
Lawlor, S.C.4
Conklin, B.R.5
-
64
-
-
0036164924
-
Markers of drug resistance in relapsing colon cancer
-
Lazaris, A. C., Kavantzas, N. G., Zorzos, H. S., Tsavaris, N. V., and Davaris, P. S. Markers of drug resistance in relapsing colon cancer. J. Cancer Res. Clin. Oncol., 128: 114-118, 2002.
-
(2002)
J. Cancer Res. Clin. Oncol.
, vol.128
, pp. 114-118
-
-
Lazaris, A.C.1
Kavantzas, N.G.2
Zorzos, H.S.3
Tsavaris, N.V.4
Davaris, P.S.5
-
65
-
-
0031018610
-
Heat shock response: Pathophysiological implications
-
Leppa, S., and Sistonen, L. Heat shock response: pathophysiological implications. Ann. Med., 29: 73-78, 1997.
-
(1997)
Ann. Med.
, vol.29
, pp. 73-78
-
-
Leppa, S.1
Sistonen, L.2
-
66
-
-
0031783644
-
Expression of differentiation-related genes in colorectal cancer: Possible implications for prognosis
-
van Belzen, N., Dinjens, W. N., Eussen, B. H., and Bosman, F. I. Expression of differentiation-related genes in colorectal cancer: possible implications for prognosis. Histol. Histopathol. 13: 1233-1242, 1998.
-
(1998)
Histol. Histopathol.
, vol.13
, pp. 1233-1242
-
-
Van Belzen, N.1
Dinjens, W.N.2
Eussen, B.H.3
Bosman, F.I.4
-
67
-
-
0025743989
-
Nucleolar protein B23 translocation after deferoxamine treatment in a human leukemia cell line
-
Yung, B. Y., Yang, Y. H., and Bor, A. M. Nucleolar protein B23 translocation after deferoxamine treatment in a human leukemia cell line. Int. J. Cancer, 48: 779-784, 1991.
-
(1991)
Int. J. Cancer
, vol.48
, pp. 779-784
-
-
Yung, B.Y.1
Yang, Y.H.2
Bor, A.M.3
-
68
-
-
0034729458
-
Low levels of NPM gene expression in UV-sensitive human cell lines
-
Hirano, J., Wang, X., Kita, K., Higuchi, Y., Nakanishi, H., Uzawa, K., Yokoe, H., Tanzawa, H., Yamaura, A., Yamamori, H., Nakajima, N., Nishikiori, C., and Suzuki, N. Low levels of NPM gene expression in UV-sensitive human cell lines. Cancer Lett., 153: 183-188, 2000.
-
(2000)
Cancer Lett.
, vol.153
, pp. 183-188
-
-
Hirano, J.1
Wang, X.2
Kita, K.3
Higuchi, Y.4
Nakanishi, H.5
Uzawa, K.6
Yokoe, H.7
Tanzawa, H.8
Yamaura, A.9
Yamamori, H.10
Nakajima, N.11
Nishikiori, C.12
Suzuki, N.13
-
69
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano, L., and Korsmeyer, S. J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun., 304, 437-444, 2003.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.J.2
-
70
-
-
0343691447
-
5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins
-
Nita, M. E., Nagawa, H., Tominaga, O., Tsuno, N., Fujii, S., Sasaki, S., Fu, C. G., Takenoue, T., Tsuruo, T., and Muto, T. 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. Br. J. Cancer, 78: 986-992, 1998.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 986-992
-
-
Nita, M.E.1
Nagawa, H.2
Tominaga, O.3
Tsuno, N.4
Fujii, S.5
Sasaki, S.6
Fu, C.G.7
Takenoue, T.8
Tsuruo, T.9
Muto, T.10
-
71
-
-
0034939638
-
Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells
-
Takechi, T., Koizumi, K., Tsujimoto, H., and Fukushima, M. Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells. Jpn. J. Cancer Res., 92: 696-703, 2001.
-
(2001)
Jpn. J. Cancer Res.
, vol.92
, pp. 696-703
-
-
Takechi, T.1
Koizumi, K.2
Tsujimoto, H.3
Fukushima, M.4
-
72
-
-
0037990003
-
Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: A novel genomic predictor of clinical response to flouropyrimidine-based chemotherapy
-
Cohen, V., Panet-Raymond, V., Sabbaghian, N., Morin, I., Batist, G., and Rozen, R. Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to flouropyrimidine-based chemotherapy. Clin. Cancer Res., 9: 1611-1615, 2003.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1611-1615
-
-
Cohen, V.1
Panet-Raymond, V.2
Sabbaghian, N.3
Morin, I.4
Batist, G.5
Rozen, R.6
-
73
-
-
0033748796
-
p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines
-
Petak, I., Tillman, D. M., and Houghton, J. A. p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines. Clin. Cancer Res., 6: 4432-4441, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4432-4441
-
-
Petak, I.1
Tillman, D.M.2
Houghton, J.A.3
-
74
-
-
0032993145
-
Mismatch repair proficiency and in vitro response to 5-fluorouracil
-
Carethers, J. M., Chauhan, D. P., Fink, D., Nebel, S., Bresalier, R. S., Howell, S. B., and Boland, C. R. Mismatch repair proficiency and in vitro response to 5-fluorouracil. Gastroenterology, 117: 123-131, 1999.
-
(1999)
Gastroenterology
, vol.117
, pp. 123-131
-
-
Carethers, J.M.1
Chauhan, D.P.2
Fink, D.3
Nebel, S.4
Bresalier, R.S.5
Howell, S.B.6
Boland, C.R.7
-
75
-
-
0033778049
-
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
-
Hemminki, A., Mecklin, J. P., Jarvinen, H., Aaltonen, L. A., and Joensuu, H. Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology, 119: 921-928, 2000.
-
(2000)
Gastroenterology
, vol.119
, pp. 921-928
-
-
Hemminki, A.1
Mecklin, J.P.2
Jarvinen, H.3
Aaltonen, L.A.4
Joensuu, H.5
-
76
-
-
0038002279
-
Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
-
Ribic, C. M., Sargent, D. J., Moore, M. J., Thibodeau, S. N., French, A. J., Goldberg, R. M., Hamilton, S. R., Laurent-Puig, P., Gryfe, R., Shepherd, L. E., Tu, D., Redston, M., and Gallinger, S. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N. Engl. J. Med., 349: 247-257, 2003.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 247-257
-
-
Ribic, C.M.1
Sargent, D.J.2
Moore, M.J.3
Thibodeau, S.N.4
French, A.J.5
Goldberg, R.M.6
Hamilton, S.R.7
Laurent-Puig, P.8
Gryfe, R.9
Shepherd, L.E.10
Tu, D.11
Redston, M.12
Gallinger, S.13
-
77
-
-
0034690610
-
Association of tumor site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
-
Elsaleh, H., Joseph, D., Grieu, F., Zeps, N., Spry, N., and Iacopetta, B. Association of tumor site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer. Lancet, 355: 1745-1750, 2000.
-
(2000)
Lancet
, vol.355
, pp. 1745-1750
-
-
Elsaleh, H.1
Joseph, D.2
Grieu, F.3
Zeps, N.4
Spry, N.5
Iacopetta, B.6
-
78
-
-
0032585232
-
Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
-
Cunningham, D., Pyrhonen, S., James, R. D., Punt, C. J., Hickish, T. F., Heikkila, R., Johannesen, T. B., Starkhammar, H., Topham, C. A., Awad, L., Jacques, C., and Herait, P. Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet, 352: 1413-1418, 1998.
-
(1998)
Lancet
, vol.352
, pp. 1413-1418
-
-
Cunningham, D.1
Pyrhonen, S.2
James, R.D.3
Punt, C.J.4
Hickish, T.F.5
Heikkila, R.6
Johannesen, T.B.7
Starkhammar, H.8
Topham, C.A.9
Awad, L.10
Jacques, C.11
Herait, P.12
-
79
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as firstline treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard, J. Y., Cunningham, D., Roth, A. D., Navarro, M., James, R. D., Karasek, P., Jandik, P., Iveson, T., Carmichael, J., Alakl, M., Gruia, G., Awad, L., and Rougier, P. Irinotecan combined with fluorouracil compared with fluorouracil alone as firstline treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet, 355: 1041-1047, 2000.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
80
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz, F., Hwang, P. M., Torrance, C., Waldman, T., Zhang, Y., Dillehay, L., Williams, J., Lengauer, C., Kinzler, K. W., and Vogelstein, B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Investig., 104: 263-269, 1999.
-
(1999)
J. Clin. Investig.
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vogelstein, B.10
-
81
-
-
0029962567
-
Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
-
Yang, B., Eshleman, J. R., Berger, N. A., and Markowitz, S. D. Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clin. Cancer Res., 2: 1649-1657, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1649-1657
-
-
Yang, B.1
Eshleman, J.R.2
Berger, N.A.3
Markowitz, S.D.4
-
82
-
-
0035392965
-
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses
-
Meyers, M., Wagner, M. W., Hwang, H. S., Kinsella, T. J., and Boothman, D. A. Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. Cancer Res., 61: 5193-5201, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 5193-5201
-
-
Meyers, M.1
Wagner, M.W.2
Hwang, H.S.3
Kinsella, T.J.4
Boothman, D.A.5
-
83
-
-
0036359548
-
Hypoxia: A key regulatory factor in tumor growth
-
Harris, A. L. Hypoxia: a key regulatory factor in tumor growth. Nat. Rev. Cancer, 2: 38-47, 2002.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
84
-
-
0035915458
-
Nitric oxide-mediated regulation of chemosensitivity in cancer cells
-
Matthews, N. E., Adams, M. A., Maxwell, L. R., Gofton, T. E., and Graham, C. H. Nitric oxide-mediated regulation of chemosensitivity in cancer cells. J. Natl. Cancer Inst. (Bethesda), 93: 1879-1885, 2001.
-
(2001)
J. Natl. Cancer Inst. (Bethesda)
, vol.93
, pp. 1879-1885
-
-
Matthews, N.E.1
Adams, M.A.2
Maxwell, L.R.3
Gofton, T.E.4
Graham, C.H.5
-
85
-
-
0026003123
-
Hypoxia-induced drug resistance: Comparison to P-glycoprotein-associated drug resistance
-
Sakata, K., Kwok, T. T., Murphy, B. J., Laderoute, K. R., Gordon, G. R., and Sutherland, R. M. Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance. Br. J. Cancer, 64: 809-814, 1991.
-
(1991)
Br. J. Cancer
, vol.64
, pp. 809-814
-
-
Sakata, K.1
Kwok, T.T.2
Murphy, B.J.3
Laderoute, K.R.4
Gordon, G.R.5
Sutherland, R.M.6
-
86
-
-
0033808725
-
Oxygen regulation of gene expression: A study in opposites
-
D'Angio, C. T., and Finkelstein, J. N. Oxygen regulation of gene expression: a study in opposites. Mol. Genet. Metab., 71: 371-380, 2000.
-
(2000)
Mol. Genet. Metab.
, vol.71
, pp. 371-380
-
-
D'Angio, C.T.1
Finkelstein, J.N.2
-
87
-
-
0030946752
-
Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products
-
Djelloul, S., Forgue-Lafitte, M. E., Hermelin, B., Mareel, M., Bruyneel, E., Baldi, A., Giordano, A., Chastre, E., and Gespach, C. Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products. FEBS Lett., 406: 234-242, 1997.
-
(1997)
FEBS Lett.
, vol.406
, pp. 234-242
-
-
Djelloul, S.1
Forgue-Lafitte, M.E.2
Hermelin, B.3
Mareel, M.4
Bruyneel, E.5
Baldi, A.6
Giordano, A.7
Chastre, E.8
Gespach, C.9
-
88
-
-
0033621170
-
Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: The predominant role of hMLH1
-
Wheeler, J. M., Beck, N. E., Kim, H. C., Tomlinson, I. P., Mortensen, N. J., and Bodmer, W. F. Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1. Proc. Natl. Acad. Sci. USA, 96: 10296-10301, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10296-10301
-
-
Wheeler, J.M.1
Beck, N.E.2
Kim, H.C.3
Tomlinson, I.P.4
Mortensen, N.J.5
Bodmer, W.F.6
-
89
-
-
0030817069
-
Screening the p53 status of human cell lines using a yeast functional assay
-
Jia, L. Q., Osada, M., Ishioka, C., Gamo, M., Ikawa, S., Suzuki, T., Shimodaira, H., Niitani, T., Kudo, T., Akiyama, M., Kimura, N., Matsuo, M., Mizusawa, H., Tanaka, N., Koyama, H., Namba, M., Kanamaru, R., and Kuroki, T. Screening the p53 status of human cell lines using a yeast functional assay. Mol. Carcinog., 19: 243-253, 1997.
-
(1997)
Mol. Carcinog.
, vol.19
, pp. 243-253
-
-
Jia, L.Q.1
Osada, M.2
Ishioka, C.3
Gamo, M.4
Ikawa, S.5
Suzuki, T.6
Shimodaira, H.7
Niitani, T.8
Kudo, T.9
Akiyama, M.10
Kimura, N.11
Matsuo, M.12
Mizusawa, H.13
Tanaka, N.14
Koyama, H.15
Namba, M.16
Kanamaru, R.17
Kuroki, T.18
-
90
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., Jr., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
Myers, T.G.4
Fan, S.5
Mutoh, M.6
Scudiero, D.A.7
Monks, A.8
Sausville, E.A.9
Weinstein, J.N.10
Friend, S.11
Fornace Jr., A.J.12
Kohn, K.W.13
-
91
-
-
0030475069
-
Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines
-
Cottu, P. H., Muzeau, F., Estreicher, A., Flejou, J. F., Iggo, R., Thomas, G., and Hamelin, R. Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines. Oncogene, 13: 2727-2730, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 2727-2730
-
-
Cottu, P.H.1
Muzeau, F.2
Estreicher, A.3
Flejou, J.F.4
Iggo, R.5
Thomas, G.6
Hamelin, R.7
-
92
-
-
0025152051
-
p53 mutations in colorectal cancer
-
Rodrigues, N. R., Rowan, A., Smith, M. E., Kerr, I. B., Bodmer, W. F., Gannon, J. V., and Lane, D. P. p53 mutations in colorectal cancer. Proc. Natl. Acad. Sci. USA. 87: 7555-7559, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7555-7559
-
-
Rodrigues, N.R.1
Rowan, A.2
Smith, M.E.3
Kerr, I.B.4
Bodmer, W.F.5
Gannon, J.V.6
Lane, D.P.7
-
93
-
-
0029841372
-
DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells
-
Matsui, S. I., Arredondo, M. A., Wrzosek, C., and Rustum, Y. M. DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells. Cancer Res., 56: 4715-4723, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4715-4723
-
-
Matsui, S.I.1
Arredondo, M.A.2
Wrzosek, C.3
Rustum, Y.M.4
-
94
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548-5550, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
Willson, J.K.4
Markowitz, S.D.5
Kinzler, K.W.6
Vogelstein, B.7
-
95
-
-
0025634118
-
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
-
Baker, S. J., Preisinger, A. C., Jessup, J. M., Paraskeva, C., Markowitz, S., Willson, J. K., Hamilton, S., and Vogelstein, B. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res., 50: 7717-7722, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 7717-7722
-
-
Baker, S.J.1
Preisinger, A.C.2
Jessup, J.M.3
Paraskeva, C.4
Markowitz, S.5
Willson, J.K.6
Hamilton, S.7
Vogelstein, B.8
-
96
-
-
0033135049
-
Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression
-
Deng, G., Chen, A., Hong, J., Chae, H. S., and Kim, Y. S. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res., 59: 2029-2033, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 2029-2033
-
-
Deng, G.1
Chen, A.2
Hong, J.3
Chae, H.S.4
Kim, Y.S.5
-
97
-
-
0035899332
-
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
-
Gayet, J., Zhou, X. P., Duval, A., Rolland, S., Hoang, J. M., Cottu, P., and Hamelin, R. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene, 20: 5025-5032, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 5025-5032
-
-
Gayet, J.1
Zhou, X.P.2
Duval, A.3
Rolland, S.4
Hoang, J.M.5
Cottu, P.6
Hamelin, R.7
|