-
2
-
-
0033986112
-
Anticancer drug targets: Growth factors and growth factor signaling
-
(2000)
J Clin Invest
, vol.105
, pp. 9-13
-
-
Gibbs, J.B.1
-
3
-
-
0033063774
-
The epidermal growth factor receptor and its inhibition in cancer therapy
-
(1999)
Pharmacol Ther
, vol.82
, Issue.2-3
, pp. 241-250
-
-
Woodburn, J.R.1
-
6
-
-
0024361386
-
Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody tO recombinant ricin A chain
-
(1989)
Cancer Res
, vol.49
, pp. 3482-3488
-
-
Masui, H.1
Kamrath, H.2
Apell, G.3
-
7
-
-
0027339486
-
Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction
-
(1993)
Br J Cancer
, vol.67
, pp. 254-261
-
-
Modjtahedi, H.1
Eccles, S.2
Box, G.3
-
8
-
-
0027935422
-
Epidermal growth factor receptors in human breast carcinoma cells: A potential selective target for transforming growth factor α-Pseudomonas exotoxin 40 fusion protein
-
(1994)
Cancer Res
, vol.54
, pp. 4703-4709
-
-
Arteaga, C.L.1
Hurd, S.D.2
Dugger, T.C.3
-
9
-
-
0029737778
-
Targeted inhibition of tumor cell growth by a bispecific single-chain toxin containing an antibody domain and TGFα
-
(1996)
Br J Cancer
, vol.74
, pp. 853-862
-
-
Schmidt, M.1
Wels, W.2
-
11
-
-
0031409362
-
Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2703-2707
-
-
Mendelsohn, J.1
-
16
-
-
0029975029
-
Tyrosine kinase inhibitors: 10. Isomeric 4-[(3-bromophenyl) amino] pyrido [d]-pyrimidines are potent ATP binding site inhibitors of the tyrosine kinase function of the epidermal growth factor receptor
-
(1996)
J Med Chem
, vol.39
, pp. 1823-1835
-
-
Rewcastle, G.W.1
Palmer, B.D.2
Thompson, A.M.3
-
19
-
-
0034104525
-
Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily
-
(2000)
Drugs
, vol.59
, pp. 753-767
-
-
Noonberg, S.B.1
Benz, C.C.2
-
24
-
-
0033025369
-
Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy: Progression from reversible to irreversible inhibitors
-
(1999)
Pharmacol Ther
, vol.82
, pp. 207-218
-
-
Fry, D.W.1
-
25
-
-
0028978269
-
4,5-bis (4-fluoroanilino) phthalimide: A selective inhibitor of the epidermal growth factor receptor signal transduction pathway with potent in vivo antitumor activity
-
(1995)
Clin Cancer Res
, vol.1
, pp. 813-821
-
-
Buchdunger, E.1
Meit, H.2
Trinks, U.3
-
26
-
-
15444361739
-
Tyrosine kinase inhibitors: 14. Structure-activity relationships for methylamino-substituted derivatives of 4-[(3-bromophenyl)amino]-6-(methylamino)-pyrido [3,4-d] pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase actitvity of receptors for the EGF family of growth factors
-
(1998)
J Med Chem
, vol.41
, pp. 742-751
-
-
Rewcastle, G.W.1
Murray, D.K.2
Elliott, W.L.3
-
27
-
-
0034212763
-
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
-
(2000)
Cancer Res
, vol.60
, pp. 2926-2935
-
-
Bruns, C.J.1
Solorzano, C.C.2
Harbison, M.T.3
-
29
-
-
0030697807
-
PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2099-2106
-
-
Bos, M.1
Mendelsohn, J.2
Kim, Y.-M.3
-
34
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
36
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and erbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo
-
(1997)
Am J Pathol
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.V.1
Rak, J.2
Hung, M.C.3
-
39
-
-
0000238822
-
Potentiation of cytotoxic agents against human tumors in nude mice by ZD1839 (Iressa(TM)), an inhibitor of EGFR tyrosine kinase, does not require high levels of expression of EGFR
-
Presented at the American Association of Cancer Research: 2000 Apr 1-5; San Francisco, USA
-
(2000)
Proc Amer Assoc Cancer Res
, pp. 41
-
-
Sirotnak, F.M.1
Zakowsky, M.F.2
Miller, V.A.3
-
42
-
-
0027428571
-
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
-
(1992)
Cancer Res
, vol.53
, pp. 4637-4642
-
-
Fan, Z.1
Baselga, J.2
Masui, H.3
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