During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion

Journal of Immunology

Volumn 175, Issue 3, 2005, Pages 1665-1676

  Hendriks, Jenny ^a   Xiao, Yanling ^a   Rossen, John W A ^b   Van Der Sluijs, Koenraad F ^c   Suganiura, Kazuo ^d   Ishii, Naoto ^d   Borst, Jannie ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD134 ANTIGEN; CD137 ANTIGEN; CD27 ANTIGEN; CD8 ANTIGEN; LIGAND;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; EFFECTOR CELL; IMMUNE RESPONSE; INFLUENZA VIRUS; LUNG; LYMPH NODE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION; WILD TYPE;

EID: 22544437564     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.3.1665     Document Type: Article

References (48)

1. Watts, T. H., and M. A. DeBenedette. 1999. T cell costimulatory molecules other than CD28. Curr. Opin. Immunol. 11: 286-293.
2. Croft, M. 2003. Co-stimulatory members of the TNFR family: keys to effective immunity? Nat. Rev. Immunol. 3: 609-619.
3. Gravestein, L. A., and J. Borst. 1998. Tumor necrosis factor receptor family members in the immune system. Semin. Immunol. 10: 423-434.
4. Hendriks, J., Y. Xiao, and J. Borst. 2003. CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. J. Exp. Med. 198: 1369-1380.
5. Okkenhaug, K., L. Wu, K. M. Garza, J. La Rose, W. Khoo, N. Odermatt, T. W. Mak, P. Ohashi, and R. Rottapel. 2001. A point mutation in CD28 distinghuishes proliferative signals from survival signals. Nat. Immunol. 2: 325-332.
6. L and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 15: 445-455.
7. L and Bfl-1. J. Immunol. 169: 4882-4888.
8. Lens, S. M. A., K. Tesselaar, M. H. J. van Oers, and R. A. W. van Lier. 1998. Control of lymphocyte function through CD27-CD70 interactions. Semin. Immunol. 10: 491-499.
9. Gravestein, L. A., J. D. Nieland, A. M. Kruisbeek, and J. Borst. 1995. Novel mAbs reveal potent co-stimulatory activity of murine CD27. Int. Immunol. 7: 551-557.
10. Al-Shamkani, A., M. L. Birkeland, M. Puklavec, M. H. Brown, W. James, and A. N. Barclay. 1996. OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 151: 5261-5271.
11. Gramaglia, I., A. D. Weinberg, M. Lemon, and M. Croft. 1998. Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J. Immunol. 161: 6510-6517.
12. Pollok, K. E, Y.-J. Kim, Z. Zhou, J. Hurtado, K. K. Kim, R. T. Pickard, and B. S. Kwon. 1993. Inducible T cell antigen 4-1BB: analysis of expression and function. J. Immunol. 150: 771-781.
13. Cooper, D., P. Bansal-Pakala, and M. Croft. 2002. 4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity. Eur. J. Immunol. 32: 521-529.
14. Oshima, H., H. Nakano, C. Nohara, T. Kobata, A. Nakajima, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, T. Muto, H. Yagita, and K. Okumura. 1998. Characterization of murine CD70 by molecular cloning and mAb. Int. Immunol. 10: 517-526.
15. Tesselaar, K., Y. Xiao, R. Arens, G. M. W. van Schijndel, D. H. Schuurhuis, R. Mebius, J. Borst, and R. A. W. van Lier. 2003. Expression of the murine CD27 ligand CD70 in vitro and in vivo. J. Immunol. 170: 33-40.
16. Stüber, E., M. Neurath, D. Calderhead, H. P. Fell, and W. Strober. 1995. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 2: 507-521.
17. Futagawa, T., H. Akiba, T. Kodama, K. Takeda, Y. Hosoda, H. Yagita, and K. Okumura. 2001. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int. Immunol. 14: 275-286.
18. Arens, R., K. Tesselaar, G. M. W. van Schijndel, P. A. Baars, S. T. Pals, P. Krimpenfort, J. Borst, M. H. J. van Oers, and R. A. W. van Lier. 2001. Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNγ-mediated B cell depletion. Immunity 15: 801-812.
19. Tesselaar, K., R. Arens, G. M. W. van Schijndel, P. A. Baars, M. A. van der Valk, J. Borst, M. H. J. van Oers, and R. A. W. van Lier. 2003. Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions. Nat. Immunol. 4: 49-54.
20. Murata, K., M. Nose, L. C. Ndhlovu, T. Sato, K. Sugamura, and N. Ishii. 2002. Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases. J. Immunol. 169: 4628-4636.
21. Zhu, G., D. B. Flies, K. Tamada, Y. Sun, M. Rodriguez, Y.-X. Fu, and L. Chen. 2001. Progressive deletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Eα-transgenic mice. J. Immunol. 167: 2671-2676.
22. Maxwell, J. R., A. Weinberg, R. Prell, and A. T. Vella. 2000. Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion. J. Immunol. 164: 107-112.
23. Takahashi, C., R. S. Mittler, and A. T. Vella. 1999. 4-1BB is a bona fide CD8 T cell survival signal. J. Immunol. 162: 5037-5040.
24. + T cell formation. J. Exp. Med. 199: 1595-1605.
25. Hendriks, J., L. A. Gravestein, K. Tesselaar, R. A. W. van Lier, T. N. M. Schumacher, and J. Borst. 2000. CD27 is required for generation and long-term maintenance of T cell immunity. Nat. Immunol. 1: 433-440.
26. Tan, J. T., J. K. Whitmire, R. Ahmed, T. C. Pearson, and C. P. Larsen. 1999. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J. Immunol. 163: 4859-4868.
27. DeBenedette, M., T. Wen, M. Bachmann, P. S. Ohashi, B. H. Barber, K. L. Stocking, J. J. Peschon, and T. Watts. 1999. Analysis of 4-1BB ligand (4-1 BBD-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol. 163: 4833-4841.
28. Bertram, E. M., P. Lau, and T. Watts. 2002. Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. J. Immunol. 168: 3777-3785.
29. Kopf, M., C. Ruedl, N. Schmitz, A. Gallimore, K. Lefrang, B. Ecabert, B. Odermatt, and M. F. Bachmann. 1999. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 11: 699-708.
30. Chen, A. I., A. J. McAdam, J. E. Buhlmann, S. Scott, M. L. Lupher, E. A. Greenfield, P. R. Baum, W. C. Fanslow, D. M. Calderhead, G. J. Freeman, and A. H. Sharpe. 1999. Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity 11: 689-698.
31. Murata, K., N. Ishii, H. Takano, S. Miura, L. C. Ndhlovu, M. Nose, T. Noda, and K. Sugamura. 2000. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med. 191: 365-374.
32. Gramaglia, I., A. Jember, S. D. Pippig, A. D. Weinberg, N. Killeen, and M. Croft. 2000. The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J. Immunol. 165: 3043-3050.
33. Humphreys, I. R., G. Walzl, L. Edwards, A. Rae, S. Hill, and T. Hussell. 2003. A critical role for OX40 in T cell-mediated immunopathology during lung infection. J. Exp. Med 8: 1237-1242.
34. Bansal-Pakala, P., B. S. Halteman, M. H.-Y. Cheng, and M. Croft. 2004. Costimulation of CD8 T-cell responses by OX40. J. Immunol. 172: 4821-4825.
35. Dawicki, W., E. M. Bertram, A. H. Sharpe, and T. H. Watts. 2004. 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses. J. Immunol. 173: 5944-5951.
36. Salek-Ardakani, S., J. Song, B. S. Halteman, A. G. Jember, H. Akiba, H. Yagita, and M. Croft. 2003. OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation. J. Exp. Med. 198: 315-324.
37. + memory T cells by viral variants. J. Exp. Med. 190: 1319-1328.
38. Xiao, Y., J. Hendriks, P. Langerak, H. Jacobs, and J. Borst. 2004. CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation. J. Immunol. 172: 7432-7441.
39. Ward, C. L., M. H. Dempsey, C. J. A. Ring, R. E. Kempson, L. Zhang, D. Gor, B. W. Snowden, and M. Tisdale. 2004. Design and performance testing of quantitative real time PCR assays for influenza A and B viral load measurement. J. Clin. Virol. 29: 179-188.
40. + T cell responses. J. Immunol. 166: 4627-4633.
41. Bertram, E. M., W. Dawicki, B. Sedgmen, J. L. Bramson, D. H. Lynch, and T. H. Watts. 2004. A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo. J. Immunol. 172: 981-988.
42. + cytotoxic T cell responses in vivo. J. Immunol. 172: 6039-6046.
43. Van Stipdonk, M. J. B., E. E. Lemmens, and S. P. Schoenberger. 2001. Naive CTLs require a single brief period of antigen stimulation for clonal expansion and differentiation. Nat. Immunol. 4: 361-365.
44. + T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2: 415-422.
45. Schluns, K. S., and L. Lefrancois. 2003. Cytokine control of memory T-cell development and survival. Nat. Rev. Immunol. 3: 269-279.
46. + T lymphocytes. Nature 421: 852-856.
47. Shedlock, D. J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300: 337-339.
48. Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300: 339-342.