A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo

Journal of Immunology

Volumn 172, Issue 2, 2004, Pages 981-988

  Bertram, Edward M ^a,d   Dawicki, Wojciech ^a   Sedgmen, Bradley ^a   Bramson, Jonathan L ^b   Lynch, David H ^c   Watts, Tania H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c AMGEN INC   (United States)

^d Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD137 ANTIGEN; CD28 ANTIGEN; CD8 ANTIGEN; INFLUENZA VACCINE; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNITY; INFLUENZA; INFLUENZA VIRUS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VACCINATION;

EID: 0842268271     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.2.981     Document Type: Article

References (52)

1. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
2. Lenschow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233.
3. Gravestein, L. A., and J. Borst. 1998. Tumor necrosis factor receptor family members in the immune system. Semin. Immunol. 10:423.
4. Watts, T. H., and M. A. DeBenedette. 1999. T cell costimulatory molecules other than CD28. Curr. Opin. Immunol. 11:286.
5. Maxwell, J. R., A. Weinberg, R. A. Prell, and A. T. Vella. 2000. Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion. J. Immunol. 164:107.
6. L and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 15:445.
7. Pippig, S. D., C. Pena-Rossi, J. Long, W. R. Godfrey, D. J. Fowell, S. L. Reiner, M. L. Birkeland, R. M. Locksley, A. N. Barclay, and N. Killeen. 1999. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J. Immunol. 163:6520.
8. Chen, A. I., A. J. McAdam, J. E. Buhlmann, S. Scott, M. L. Lupher, Jr., E. A. Greenfield, P. R. Baum, W. C. Fanslow, D. M. Calderhead, G. J. Freeman, et al. 1999. Ox40-ligand has a critical costimulatory role in dendritic cell: T cell interactions. Immunity 11:689.
9. Murata, K., N. Ishii, H. Takano, S. Miura, L. C. Ndhlovu, M. Nose, T. Noda, and K. Sugamura. 2000. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med. 191:365.
10. Hurtado, J. C., Y. J. Kim, and B. S. Kwon. 1997. Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death. J. Immunol. 158:2600.
11. Cannons, J. L., P. Lau, B. Ghumman, M. A. DeBenedette, H. Yagita, K. Okumura, and T. H. Watts. 2001. 4-1BBL induces cell division, sustains survival and enhances effector function of CD4 and CD8 T cells with similar efficacy. J. Immunol. 167:1313.
12. L and Bfl-1. J. Immunol. 169:4882.
13. DeBenedette, M. A., T. Wen, M. F. Bachmann, P. S. Ohashi, B. H. Barber, K. L. Stocking, J. J. Peschon, and T. H. Watts. 1999. Analysis of 4-1BB ligand-deficient mice and of mice lacking both 4-1BB ligand and CD28 reveals a role for 4-1BB ligand in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol. 163:4833.
14. Bertram, E. M., P. Lau, and T. H. Walls. 2002. Temporal segregation of CD28 versus 4-1BBL-mediated costimulation: 4-1BBL influences T cell numbers late in the primary response and regulates the size of the memory response following influenza infection. J. Immunol. 168:3777.
15. Takahashi, C., R. S. Mittler, and A. T. Vella. 1999. Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal. J. Immunol. 162:5037.
16. Tan, J. T., J. K. Whitmire, R. Ahmed, T. C. Pearson, and C. P. Larsen. 1999. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J. Immunol. 163:4859.
17. Tan, J. T., J. K. Whitmire, K. Murali-Krishna, R. Ahmed, J. D. Altman, R. S. Mittler, A. Sette, T. C. Pearson, and C. P. Larsen. 2000. 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination. J. Immunol. 164:2320.
18. Cooper, D., P. Bansal-Pakala, and M. Croft. 2002. 4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity. Eur. J. Immunol. 32:521.
19. Mercado, R., S. Vijh, S. E. Allen, K. Kerksiek, I. M. Pilip, and E. G. Pamer. 2000. Early programming of T cell populations responding to bacterial infection. J. Immunol. 165:6833.
20. Wong, P., and E. G. Pamer. 2001. Cutting edge: antigen-independent CD8 T cell proliferation. J. Immunol. 166:5864.
21. van Stipdonk, M. J., E. E. Lemmens, and S. P. Schoenberger. 2001. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat. Immunol. 2:423.
22. + T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2:415.
23. Sprent, J., and C. D. Surh. 2001. Generation and maintenance of memory T cells. Curr. Opin. Immunol. 13:248.
24. + T cells after infection. Nat. Immunol. 3:619.
25. + T lymphocyte responses. Nat. Immunol. 4:361.
26. Lumsden, J. M., J. M. Roberts, N. L. Harris, R. J. Peach, and F. Ronchese. 2000. Differential requirement for CD80 and CD80/86-dependent costimulation in the lung immune response to an influenza virus infection. J. Immunol. 2000:79.
27. Shahinian, A., K. Pfeffer, K. P. Lee, T. M. Kundig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261:609.
28. Miller, R. E., J. Jones, T. Le, J. Whitmore, N. Boiani, B. Gliniak, and D. H. Lynch. 2002.4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner. J. Immunol. 169:1792.
29. 2-microglobulin constructs. J. Immunol. 160:1598.
30. Ng, P., R. J. Parks, D. T. Cummings, C. M. Evelegh, and F. L. Graham. 2000. An enhanced system for construction of adenoviral vectors by the two-plasmid rescue method. Hum. Gene Ther. 11:693.
31. - T lymphocytes by 4-1BB ligand. J. Immunol. 158:551.
32. Saoulli, K., S. Y. Lee, J. L. Cannons, W. C. Yeh, A. Santana, M. D. Goldstein, N. Bangia, M. A. DeBenedette, T. W. Mak, Y. Choi. et al. 1998. CD28-independent. TRAF2-dependent costimulation of resting T cells by 4-1BB ligand. J. Exp. Med. 187:1849.
33. + T cell responses. Nat. Immunol. 3:536.
34. + T-cell response to readily eliminated and persistent viruses. Philos. Trans. R. Soc. London B 355:1093.
35. + T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J. Exp. Med. 186:47.
36. Mittler, R. S., T. S. Bailey, K. Klussman, M. D. Trailsmith, and M. K. Hoffmann. 1999. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J. Exp. Med. 190:1535.
37. Arch, R. H., and C. B. Thompson. 1998. 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κB. Mol. Cell. Biol. 18:558.
38. Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727.
39. Cannons, J. L., K. P. Hoeflich, J. R. Woodgett, and T. H. Watts. 1999. Role of the stress kinase pathway in signaling via the T cell costimulatory receptor 4-1BB. J. Immunol. 163:2990.
40. Cannons, J. L., Y. Choi, and T. H. Watts. 2000. Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response. J. Immunol. 165:6193.
41. Harhaj, E. W., S. B. Maggirwar, L. Good, and S. C. Sun. 1996. CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rcl heterodimers. Mol. Cell. Biol. 16:6736.
42. +-T-cell-deficient mice. J. Virol. 76:12388.
43. Bertram, E. M., A. Tafuri, A. Shahinian, V. S. F. Chan, L. Hunziker, M. Recher, P. S. Ohashi, T. W. Mak, and T. H. Watts. 2002. Role of ICOS versus CD28 in anti-viral immunity. Eur. J. Immunol. 32:3376.
44. + T cells. Proc. Natl. Acad. Sci. USA 96:8597.
45. + T cells undergoing primary and secondary responses to infection in the same host. J. Immunol. 170:4933.
46. Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300:339.
47. Shedlock, D. J., J. K. Whitmire, J. Tan, A. S. MacDonald, R. Ahmed, and H. Shen. 2003. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J. Immunol. 170:2053.
48. + T cell memory. Science 297:2060.
49. + T cell responses to an influenza A virus. J. Immunol. 167:2753.
50. Alegre, M. L., K. A. Frauwirth, and C. B. Thompson. 2001. T-cell regulation by CD28 and CTLA-4. Nat. Rev. Immunol. 1:220.
51. + T cell immunodominance in primary and secondary influenza virus infections. J. Exp. Med. 198:399.
52. - accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity. 18:643.