CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation

Journal of Immunology

Volumn 172, Issue 12, 2004, Pages 7432-7441

  Xiao, Yanling ^a   Hendriks, Jenny ^a   Langerak, Petra ^a   Jacobs, Heinz ^a   Borst, Jannie ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GERMINAL CENTER; IMMUNOHISTOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; VIRUS INFECTION;

EID: 2942586926     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.12.7432     Document Type: Article

References (44)

1. Lens, S. M., K. Tesselaar, M. H. J. van Oers, and R. A. W. van Lier. 1998. Control of lymphocyte function through CD27-CD70 interactions. Semin. Immunol. 10:491.
2. Oshima, H., H. Nakano, C. Nohara, T. Kobata, A. Nakajima, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, T. Muto, H. Yagita, and K. Okumura. 1998. Characterization of murine CD70 by molecular cloning and mAb. Int. Immunol. 10:517.
3. Tesselaar, K., Y. Xiao, R. Arens, G. M. W. van Schijndel, D. H. Schuurhuis, R. Mebius, J. Borst, and R. A. W. van Lier. 2003. Expression of the murine CD27 ligand CD70 in vitro and in vivo. J. Immunol. 170:33.
4. Futagawa, T., H. Akiba, T. Kodama, K. Takeda, Y. Hosoda, H. Yagita, and K. Okumura, 2002. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int. Immunol. 14:275.
5. Hintzen, R. Q., S. M. Lens, K. Lammers, H. Kuiper, M. P. Beckmann, and R. A. W. van Lier. 1995. Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation. J. Immunol. 154:2612.
6. Gravestein, L. A., J. D. Nieland, A. M. Kruisbeek, and J. Borst. 1995. Novel monoclonal antibodies reveal potent costimulatory activity of murine CD27. Int. Immunol. 7:551.
7. Hendriks, J., L. A. Gravestein, K. Tesselaar, R. A. W. van Lier, T. N. M. Schumacher, and J. Borst. 2000. CD27 is required for generation and long-term maintenance of T cell immunity. Nat. Immunol. 1:433.
8. Hendriks, J., Y. Xiao, and J. Borst. 2003. CD27 promotes activated T cell survival and complements CD28 in generation and establishment of the effector T cell pool. J. Exp. Med. 198:1369.
9. Maurer, D., W. Holter, O. Majdic, G. F. Fischer, and W. Knapp. 1990. CD27 expression by a distinct subpopulation of human B lymphocytes. Eur. J. Immunol. 20:2679.
10. Agematsu, K., T. Kobata, F.-C. Yang, T. Nakazawa, K. Fukushima, M. Kitahara, T. Mori, K. Sugita, C. Morimoto, and A. Komiyama. 1995. CD27/CD70 interaction directly drives B cell IgG and IgM synthesis. Eur. J. Immunol. 25:2825.
11. van Oers, M. H. J., S. T. Pals, L. M. Evers, C. E. van der Schoot, G. Koopman, J. M. G. Bonfrer, R. Q. Hintzen, A. E. G. Kr. von dem Borne, and R. A. W. van Lier. 1993. Expression and release of CD27 in human malignancies. Blood 82:3430.
12. Tangye, S. G., Y.-J. Liu, G. Aversa, J. H. Philips, and J. E. de Vries. 1998. Identification of functional human splenic memory B cells by expression of CD148 and CD27. J. Exp. Med. 188:1691.
13. Agematsu, K., S. Hokibara, H. Nagumo, and A. Komiyama. 2000. CD27: a memory B-cell marker. Immunol. Today 21:204.
14. + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 188:1679.
15. + B lymphocyte subset. J. Immunol. 148:3700.
16. + B cells and helper T cells in immunoglobulin production. Eur. J. Immunol. 27:2073.
17. Jung, J., J. Choe, L. Li, and Y. S. Choi. 2000. Regulation of CD27 expression in the course of germinal center B cell differentiation: the pivotal role of IL-10. Eur. J. Immunol. 30:2437.
18. Kobata, T., S. Jacquot, S. Kozlowski, K. Agematsu, S. F. Schlossman, and C. Morimoto. 1995. CD27-CD70 interactions regulate B-cell activation by T cells. Proc. Natl. Acad. Sci. USA 92:11249.
19. Nagumo, H., K. Agematsu, K. Shinozaki, S. Hokibara, S. Ito, M. Takamoto, T. Nikaido, K. Yasui, Y. Uehara, A. Yachie, and A. Komiyama. 1998. CD27/CD70 interaction augments IgE secretion by promoting the differentiation of memory B cells into plasma cells. J. Immunol. 161:6496.
20. Jacquot, S., T. Kobata, S. Iwata, C. Morimoto, and S. F. Schlossman. 1997. CD154/CD40 and CD70/CD27 interactions have different and sequential functions in T cell-dependent B cell responses. J. Immunol. 159:2652.
21. Agematsu, K., H. Nagumo, Y. Oguchi, T. Nakazawa, K. Fukushima, K. Yasui, S. Ito, T. Kobata, C. Morimoto, and A. Komiyama, 1998. Generation of plasma cells from peripheral blood memory B cells: synergistic effect of interleukin-10 and CD27/CD70 interaction. Blood 91:173.
22. Lens, S. M. A., R. de Jong, B. Hooibrink, G. Koopman, S. T. Pals, M. H. J. van Oers, and R. A. W. van Lier. 1996. Phenotype and function of human B cells expressing CD70 (CD27 ligand), Eur. J. Immunol. 26:2964.
23. Lens, S. M. A., R. M. J. Keehnen, M. H. J. van Oers, R. A. W. van Lier, S. T. Pals, and G. Koopman, 1996. Identification of a novel subpopulation of germinal center B cells characterized by expression of IgD and CD70. Eur. J. Immunol. 26:1007.
24. Shahinian, A., K. Pfeffrer, K. P. Lee, T. M. Kündig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261:609.
25. Ferguson, S. E., S. Han, G. Kelsoe, and C. B. Thompson. 1996. CD28 is required for germinal center formation. J. Immunol. 156:4576.
26. Boriello, F., M. P. Sethna, S. D. Boyd, A. N. Schweitzer, E. A. Tivol, D. Jacoby, T. B. Strom, E. M. Simpson, G. J. Freeman, and A. H. Sharpe. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 6:303.
27. + T cells. J. Exp. Med. 179:819.
28. Rolink, A. G., J. Andersson, and F. Melchers. 1998. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 28:3738.
29. Jacobs, H., Y. Fukita, G. T. J. van der Horst, J. de Boer, G. Weeda, J. Essers, N. de Wind, B. P. Engelward, L. Samson, S. Verbeek, et al. 1998. Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice. J. Exp. Med. 187:1735.
30. Taylor, P. R., M. C. Pickering, M. H. Kosco-Vilbois, M. J. Walport, M. Botto, S. Gordon, and L. Martinez-Pomares. 2002. The follicular dendritic cell restricted epitope, FDC-M2, is complement C4: localization of immune complexes in mouse tissues. Eur. J. Immunol. 32:1888.
31. Pasparakis, M., L. Alexopolou, V. Episkopou, and G. Kollias. 1996. Immune and inflammatory responses in TNFα-deficient mice: a critical requirement for TNFα in the formation of primary B cell follicles, follicar dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184:1397.
32. Loder, F., B. Mutschler, R. J. Ray, C. J. Paige, P. Sideras, R. Torres, M. C. Lamers, and R. Carsetti. 1999. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190:75.
33. Butcher, E. C., R. V. Rouse, R. L. Coffman, C. N. Nottenburg, R. R. Hardy, and I. L. Weissman. 1982. Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. J. Immunol. 129:2698.
34. Han, S., B. Zheng, D. G. Schatz, E. Spanopoulou, and G. Kelsoe. 1996. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science 274:2094.
35. Diaz, M., and P. Casali. 2002. Somatic immunoglobulin hypermutation. Curr. Opin. Immunol. 121:235.
36. MacLennan, I. C. M. 1994. Germinal centers. Annu. Rev. Immunol. 12:117.
37. Kelsoe, G. 1996. Life and death in germinal centers (redux). Immunity 4:107.
38. - accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity 18:643.
39. Walker, L. S. K., A. Gulbranson-Judge, S. Flynn, T. Brocker, C. Raykundakia, M. Goodall, R. Forster, M. Lipp, and P. Lane. 1999. Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J. Exp. Med. 190:1115.
40. Stueber, E., and W. Strober. 1996. The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. J. Exp. Med. 183:979.
41. Kopf, M., C. Ruedl, N. Schmitz, A. Gallimore, K. Lefrang, B. Ecabert, B. Odermatt, and M. F. Bachmann. 1999. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 11:699.
42. Pippig, S. D., C. Pena-Rossi, J. Long, W. R. Godfrey, D. J. Fowell, S. L. Reiner, M. L. Birkeland, R. M. Locksley, A. N. Barclay, and N. Killeen. 1999. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J. Immunol. 163:6520.
43. Murata, K., N. Ishii, H. Takano, S. Miura, L. C. Ndhlovu, M. Nose, T. Noda, and K. Sugamura. 2000. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med. 191:365.
44. Tesselaar, K., R. Arens, G. M. W. van Schijndel, P. A. Baars, M. A. van der Valk, J. Borst, M. H. J. van Oers, and R. A. W. van Lier. 2003. Lethal T cell immunodeficiency induced by chronic costimulation via CD27/CD70 interactions. Nat. Immunol. 4:49.