The Drosophila F box protein archipelago regulates dMyc protein levels in vivo

Current Biology

Volumn 14, Issue 11, 2004, Pages 965-974

  Moberg, Kenneth H ^a,b   Mukherjee, Ashim ^a   Veraksa, Alexey ^a   Artavanis Tsakonas, Spyros ^a   Hariharan, Iswar K ^a,c  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARCHIPELAGO PROTEIN, DROSOPHILA; DIMINUTIVE PROTEIN, DROSOPHILA; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; F BOX PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL CULTURE; CELL CYCLE; COMPARATIVE STUDY; CYTOLOGY; DROSOPHILA; DRUG ANTAGONISM; FLOW CYTOMETRY; FORELIMB; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOLECULAR GENETICS; MORPHOMETRICS; MUTATION; NORTHERN BLOTTING; PHYSIOLOGY; RNA INTERFERENCE; SEQUENCE ALIGNMENT; SERODIAGNOSIS;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BODY WEIGHTS AND MEASURES; CELL CYCLE; CELLS, CULTURED; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; F-BOX PROTEINS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MUTATION; PRECIPITIN TESTS; RNA INTERFERENCE; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSFECTION; WING;

ANIMALIA; HEXAPODA; METAZOA;

EID: 2642549141     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2004.04.040     Document Type: Article

References (47)

1. Grandori C., Cowley S.M., James L.P., Eisenman R.N. The Myc/Max/Mad network and the transcriptional control of cell behavior. Annu. Rev. Cell Dev. Biol. 16:2000;653-699
2. Levens D.L. Reconstructing MYC. Genes Dev. 17:2003;1071-1077
3. Fernandez P.C., Frank S.R., Wang L., Schroeder M., Liu S., Greene J., Cocito A., Amati B. Genomic targets of the human c-Myc protein. Genes Dev. 17:2003;1115-1129
4. Orian A., Van Steensel B., Delrow J., Bussemaker H.J., Li L., Sawado T., Williams E., Loo L.W., Cowley S.M., Yost C., et al. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev. 17:2003;1101-1114
5. DePinho R.A., Schreiber-Agus N., Alt F.W. myc family oncogenes in the development of normal and neoplastic cells. Adv. Cancer Res. 57:1991;1-46
6. Adams J.M., Harris A.W., Pinkert C.A., Corcoran L.M., Alexander W.S., Cory S., Palmiter R.D., Brinster R.L. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 318:1985;533-538
7. Langenau D.M., Traver D., Ferrando A.A., Kutok J.L., Aster J.C., Kanki J.P., Lin S., Prochownik E., Trede N.S., Zon L.I., et al. Myc-induced T cell leukemia in transgenic zebrafish. Science. 299:2003;887-890
8. Stewart T.A., Pattengale P.K., Leder P. Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell. 38:1984;627-637
9. Salghetti S.E., Kim S.Y., Tansey W.P. Destruction of Myc by ubiquitin-mediated proteolysis. cancer-associated and transforming mutations stabilize Myc EMBO J. 18:1999;717-726
10. Gregory M.A., Hann S.R. c-Myc proteolysis by the ubiquitin-proteasome pathway. stabilization of c-Myc in Burkitt's lymphoma cells Mol. Cell. Biol. 20:2000;2423-2435
11. Henriksson M., Bakardjiev A., Klein G., Luscher B. Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential. Oncogene. 8:1993;3199-3209
12. Lutterbach B., Hann S.R. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol. Cell. Biol. 14:1994;5510-5522
13. Pulverer B.J., Fisher C., Vousden K., Littlewood T., Evan G., Woodgett J.R. Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. Oncogene. 9:1994;59-70
14. Sears R., Nuckolls F., Haura E., Taya Y., Tamai K., Nevins J.R. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev. 14:2000;2501-2514
15. Gregory M.A., Qi Y., Hann S.R. Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J. Biol. Chem. 278:2003;51606-51612
16. Welcker M., Orian A., Jin J., Harper J.W., Eisenman R.N., Clurman B.E. The Fbw7 tumor supressor regulates GSK3 phosphorylation-dependent c-Myc protein degradation. Proc. Natl. Acad. Sci. USA. in press:2004
17. Moberg K.H., Bell D.W., Wahrer D.C., Haber D.A., Hariharan I.K. Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature. 413:2001;311-316
18. Strohmaier H., Spruck C.H., Kaiser P., Won K.A., Sangfelt O., Reed S.I. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature. 413:2001;316-322
19. Koepp D.M., Schaefer L.K., Ye X., Keyomarsi K., Chu C., Harper J.W., Elledge S.J. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science. 294:2001;173-177
20. Justice N.J., Jan Y.N. Variations on the Notch pathway in neural development. Curr. Opin. Neurobiol. 12:2002;64-70
21. Neufeld T.P., de la Cruz A.F., Johnston L.A., Edgar B.A. Coordination of growth and cell division in the Drosophila wing. Cell. 93:1998;1183-1193
22. Johnston L.A., Prober D.A., Edgar B.A., Eisenman R.N., Gallant P. Drosophila myc regulates cellular growth during development. Cell. 98:1999;779-790
23. Zaffran S., Chartier A., Gallant P., Astier M., Arquier N., Doherty D., Gratecos D., Semeriva M. A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc. Development. 125:1998;3571-3584
24. Das T., Purkayastha-Mukherjee C., D'Angelo J., Weir M. A conserved F-box gene with unusual transcript localization. Dev. Genes Evol. 212:2002;134-140
25. Jiang J., Struhl G. Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature. 391:1998;493-496
26. Theodosiou N.A., Zhang S., Wang W.Y., Xu T. slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development. Development. 125:1998;3411-3416
27. Kim S.Y., Herbst A., Tworkowski K.A., Salghetti S.E., Tansey W.P. Skp2 regulates myc protein stability and activity. Mol. Cell. 11:2003;1177-1188
28. von der Lehr N., Johansson S., Wu S., Bahram F., Castell A., Cetinkaya C., Hydbring P., Weidung I., Nakayama K., Nakayama K.I., et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol. Cell. 11:2003;1189-1200
29. Gallant P., Shiio Y., Cheng P.F., Parkhurst S.M., Eisenman R.N. Myc and Max homologs in Drosophila. Science. 274:1996;1523-1527
30. Schreiber-Agus N., Stein D., Chen K., Goltz J.S., Stevens L., DePinho R.A. Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype. Proc. Natl. Acad. Sci. USA. 94:1997;1235-1240
31. Bourbon H.M., Gonzy-Treboul G., Peronnet F., Alin M.F., Ardourel C., Benassayag C., Cribbs D., Deutsch J., Ferrer P., Haenlin M., et al. A P-insertion screen identifying novel X-linked essential genes in Drosophila. Mech. Dev. 110:2002;71-83
32. Nash P., Tang X., Orlicky S., Chen Q., Gertler F.B., Mendenhall M.D., Sicheri F., Pawson T., Tyers M. Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature. 414:2001;514-521
33. Welcker M., Singer J., Loeb K.R., Grim J., Bloecher A., Gurien-West M., Clurman B.E., Roberts J.M. Multisite phosphorylation by Cdk2 and GSK3 controls Cyclin E degradation. Mol. Cell. 12:2003;381-392
34. Orlicky S., Tang X., Willems A., Tyers M., Sicheri F. Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell. 112:2003;243-256
35. Won K.A., Reed S.I. Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E. EMBO J. 15:1996;4182-4193
36. Clurman B.E., Sheaff R.J., Thress K., Groudine M., Roberts J.M. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes Dev. 10:1996;1979-1990
37. de Celis J.F., Tyler D.M., de Celis J., Bray S.J. Notch signalling mediates segmentation of the Drosophila leg. Development. 125:1998;4617-4626
38. Go M.J., Eastman D.S., Artavanis-Tsakonas S. Cell proliferation control by Notch signaling in Drosophila development. Development. 125:1998;2031-2040
39. Spruck C.H., Strohmaier H., Sangfelt O., Muller H.M., Hubalek M., Muller-Holzner E., Marth C., Widschwendter M., Reed S.I. hCDC4 gene mutations in endometrial cancer. Cancer Res. 62:2002;4535-4539
40. Rajagopalan H., Jallepalli P.V., Rago C., Velculescu V.E., Kinzler K.W., Vogelstein B., Lengauer C. Inactivation of hCDC4 can cause chromosomal instability. Nature. 428:2004;77-81
41. Maillard I., Pear W.S. Notch and cancer. best to avoid the ups and downs Cancer Cell. 3:2003;203-205
42. Rigaut G., Shevchenko A., Rutz B., Wilm M., Mann M., Seraphin B. A generic protein purification method for protein complex characterization and proteome exploration. Nat. Biotechnol. 17:1999;1030-1032
43. Gavin A.C., Bosche M., Krause R., Grandi P., Marzioch M., Bauer A., Schultz J., Rick J.M., Michon A.M., Cruciat C.M., et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 415:2002;141-147
44. Puig O., Caspary F., Rigaut G., Rutz B., Bouveret E., Bragado-Nilsson E., Wilm M., Seraphin B. The tandem affinity purification (TAP) method. a general procedure of protein complex purification Methods. 24:2001;218-229
45. Fromont-Racine M., Rain J.C., Legrain P. Building protein-protein networks by two-hybrid mating strategy. Methods Enzymol. 350:2002;513-524
46. Worby, C.A., Simonson-Leff, N., and Dixon, J.E. (2001). RNA interference of gene expression (RNAi) in cultured Drosophila cells. Sci STKE 2001, PL1.
47. Tapon N., Ito N., Dickson B.J., Treisman J.E., Hariharan I.K. The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell. 105:2001;345-355