Cell cycle: Routine role for Ras

Current Biology

Volumn 7, Issue 4, 1997, Pages

  Downward, Julian ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031127304     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00116-3     Document Type: Review

References (26)

1. Weinberg RA: Racing to the Beginning of the Road. New York: Harmony Books; 1996.
2. Marshall CJ: Ras effectors. Curr Opin Cell Biol 1996, 8:197-204.
3. Durkin JP, Whitfield JF: Characterization of G1 transit induced by the mitogenic-oncogenic Ki-ras gene product. Mol Cell Biol 1986, 6:1386-1392.
4. Dobrowolski S, Harter M, Stacey DW : Cellular ras activity is required for passage through multiple points of the G0/ G1 phase in BALB/ c 3T3 cells. Mol Cell Biol 1994, 14:5441-5449.
5. Pardee AB: A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci USA 1974, 71:1286-1290.
6. Pledger WJ, Stiles CD, Antoniades HN, Scher CD: An ordered sequence of events is required before Balb/ c 3T3 cells become committed to DNA synthesis. Proc Natl Acad Sci USA 1978, 75:2839-2843.
7. Taylor SJ, Shalloway D: Cell cycle-dependent activation of Ras. Curr Biol 1996, 6:1621-1627.
8. McCormick F: Signal transduction: how receptors turn Ras on. Nature 1993, 363:15-16.
9. Filmus J, Robles AI, Shi W, Colombo LL, Conti CJ: Induction of cyclin D1 overexpression by activated ras. Oncogene 1994, 9:3627-3633.
10. Liu J-L, Chao J-R, Jiang M-C, Ng S-Y, Yen JJ-Y, Yang-Yen H-F:Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells. Mol Cell Biol 1995, 15:3654-3663.
11. Winston JT, Coats SR, Wang Y-Z, Pledger WJ: Regulation of the cell cycle machinery by oncogenic ras. Oncogene 1996, 12:127-134.
12. Lavoie JN, L'Allemain G, Brunei A, Müller R, Pouysségur J: Cyclin D1 expression is regulated positively by the p42/ p44 MAPK and negatively by the p38/ HOG MAPK pathway. J Biol Chem 1996, 271:20608-20616.
13. Hinds PW, Dowdy SF, Ng Eaton E, Arnold A, Weinberg RA: Function of a human cyclin gene as an oncogene. Proc Natl Acad Sci USA 1994, 91:709-713.
14. Lovec H, Sewing A, Lucibello FC, Müller R, Möröy T: Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: a link between cell cycle control and malignant transformation. Oncogene 1994, 9:323-326.
15. Peeper DS, Upton TM, Ladha MH, Neuman E, Zalvide J, Bernards R, DeCaprio JA, Ewen ME: Ras signalling linked to the cell cycle machinery by the retinoblastoma protein. Nature 1997, 386:177-181.
16. Mittnacht S, Paterson H, Olson MF, Marshall CJ: Ras signalling is required for inactivation of the tumour suppressor pRb cell cycle control protein. Curr Biol 1997, 7:219-221.
17. Land H, Parada LF, Weinberg RA: Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983, 304:596-602.
18. Franza BR, Maruyama K, Garrels JI, Ruley HE: In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell 1986, 4:409-418.
19. Ridley AJ, Paterson HF, Noble M, Land H: Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J 1988, 7:1635-1645.
20. Lloyd AC, Obermuller F, Staddon S, Barth C, McMahon M, Land H: Cooperating oncogenes target cyclin/ cdk activity. Genes Dev 1997, in press.
21. Serrano M, Gmez-Lahoz E, DePinho RA, Beach D, Bar-Sagi D: Inhibition of Ras-induced proliferation and cellular transformation by p16 INK4. Science 1995, 267:249-252.
22. Michieli P, Li W, Lorenzi MV, Miki T, Zakut R, Givol D, Pierce JH: Inhibition of oncogene-mediated transformation by ectopic expression of p21 Waf1 in NIH 3T3 cells. Oncogene 1996, 12:775-784.
23. Serrano M, Lee H-W, Chin L, Cordon-Cardo C, Beach D: Role of INK4a locus in tumor suppression and cell mortality. Cell 1997,85:27-37..
24. INK4a. Cell 1997, 88:593-602..
25. Kang J-S, Krauss RS: Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events. Mol Cell Biol 1996, 16:3370-3380.
26. Roche S, Koegl M, Courtneidge SA: The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors. Proc Natl Acad Sci USA 1994, 91:9185-9189.