-
1
-
-
0035193362
-
Exoribonucleases and their multiple roles in RNA metabolism
-
Deutscher M.P., Li Z. 2001. Exoribonucleases and their multiple roles in RNA metabolism. Prog. Nucleic Acid Res. Mol. Biol. 66, 67-105.
-
(2001)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.66
, pp. 67-105
-
-
Deutscher, M.P.1
Li, Z.2
-
2
-
-
0037195896
-
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
-
Harder J., Schroder LM. 2002. RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J. Biol. Chem. 277, 46784-46799.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46784-46799
-
-
Harder, J.1
Schroder, L.M.2
-
3
-
-
0035212431
-
Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens
-
Rosenberg H.F., Domachowske J.B. 2001. Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens. J. Leukoc. Biol. 70, 691-698.
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 691-698
-
-
Rosenberg, H.F.1
Domachowske, J.B.2
-
4
-
-
0035018435
-
Cancer chemotherapy - Ribonucleases to the rescue
-
Leland P., Raines R. 2001. Cancer chemotherapy - ribonucleases to the rescue. Chemistry and Biology. 8, 405-413.
-
(2001)
Chemistry and Biology
, vol.8
, pp. 405-413
-
-
Leland, P.1
Raines, R.2
-
6
-
-
0036137925
-
Phase II trial of a single weekly intravenous dose of rapirnase in patient with unresectable malignant mesothelioma
-
Mikulski S.M., Costanzi J.J., Vogelzang N.J., McCachren S., Taub R.N., Chun H., Mittelman A., Panella T Puccio C., Fine R., Shogen K. 2002. Phase II trial of a single weekly intravenous dose of rapirnase in patient with unresectable malignant mesothelioma. J. Clin. Oncol. 20, 274-281.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 274-281
-
-
Mikulski, S.M.1
Costanzi, J.J.2
Vogelzang, N.J.3
McCachren, S.4
Taub, R.N.5
Chun, H.6
Mittelman, A.7
Panella, T.8
Puccio, C.9
Fine, R.10
Shogen, K.11
-
7
-
-
0036594060
-
Effect of replacing the aspartis acid/glutamic acid residues of bullfrog sialic acid binding lectin with asparagine/glutamine and arginine on the inhibition of cell proliferation in murine leukemia P388 cells
-
Ogawa Y., Iwama M., Ohgi K., Tsuji T., Irie M., Itagaki T., Kobajashi H., Inokushi N. 2002. Effect of replacing the aspartis acid/glutamic acid residues of bullfrog sialic acid binding lectin with asparagine/glutamine and arginine on the inhibition of cell proliferation in murine leukemia P388 cells. Biol. Pharm. Bull. 25, 722-727.
-
(2002)
Biol. Pharm. Bull.
, vol.25
, pp. 722-727
-
-
Ogawa, Y.1
Iwama, M.2
Ohgi, K.3
Tsuji, T.4
Irie, M.5
Itagaki, T.6
Kobajashi, H.7
Inokushi, N.8
-
8
-
-
0035957231
-
Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the ribonuclease inhibitor
-
Antignani A., Naddo M., Cubellis M.V., Russo A., D'Alessio G. 2001. Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the ribonuclease inhibitor. Biochemistry. 40, 3492-3496.
-
(2001)
Biochemistry.
, vol.40
, pp. 3492-3496
-
-
Antignani, A.1
Naddo, M.2
Cubellis, M.V.3
Russo, A.4
D'Alessio, G.5
-
9
-
-
0035219058
-
RNA damage and inhibition of neoplastic endothelial cells growth: Effects of human and amphibian ribonucleases
-
Newton D.L., Kaur G., Rhim J.S., Sausville E.A., Rybak S.M. 2001. RNA damage and inhibition of neoplastic endothelial cells growth: effects of human and amphibian ribonucleases. Radiat. Res. 155, 171-174.
-
(2001)
Radiat. Res.
, vol.155
, pp. 171-174
-
-
Newton, D.L.1
Kaur, G.2
Rhim, J.S.3
Sausville, E.A.4
Rybak, S.M.5
-
10
-
-
0036856265
-
RNase 3 (ECP) is an extraordinarily stable protein among human pancreatic-type RNases
-
Maeda T., Mahara K., Kitazoe M., Futami J., Takidini A., Kosaka M., Tada H., Seno M., Yamada H. 2002. RNase 3 (ECP) is an extraordinarily stable protein among human pancreatic-type RNases. J. Biochem. (Tokyo). 132, 737-742.
-
(2002)
J. Biochem. (Tokyo)
, vol.132
, pp. 737-742
-
-
Maeda, T.1
Mahara, K.2
Kitazoe, M.3
Futami, J.4
Takidini, A.5
Kosaka, M.6
Tada, H.7
Seno, M.8
Yamada, H.9
-
11
-
-
0242499270
-
Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease (rapirnase)
-
Halicka D.H., Pozarowski P., Ita M., Ardelt W.J., Mikulski S.M., Shogen K., Darzynkiewicz Z. 2002. Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease (rapirnase). Int. J. Oncol. 21, 1245-1250.
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 1245-1250
-
-
Halicka, D.H.1
Pozarowski, P.2
Ita, M.3
Ardelt, W.J.4
Mikulski, S.M.5
Shogen, K.6
Darzynkiewicz, Z.7
-
12
-
-
0035793124
-
Bacillus intermedius ribonuclease as inhibitor of cell proliferation and membrane current
-
IIinskaya O., Decker K., Koschinski A., Dreyer F., Repp H. 2001. Bacillus intermedius ribonuclease as inhibitor of cell proliferation and membrane current. Toxicology. 156, 101-107.
-
(2001)
Toxicology
, vol.156
, pp. 101-107
-
-
Iiinskaya, O.1
Decker, K.2
Koschinski, A.3
Dreyer, F.4
Repp, H.5
-
13
-
-
0037033001
-
X-Ray structure of two crystalline forms of a Streptomycete ribonuclease with cytotoxic activity
-
Sevcik J., Urbanikova L., Leland P.A., Raines R.T. 2002. X-Ray structure of two crystalline forms of a Streptomycete ribonuclease with cytotoxic activity. J. Biol. Chem. 277, 47325-47330.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47325-47330
-
-
Sevcik, J.1
Urbanikova, L.2
Leland, P.A.3
Raines, R.T.4
-
14
-
-
0034832684
-
Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction cell death via apoptosis
-
Olmo N., Turnay J., Gonzalez de Butitrago G., Lopez de Silanes I., Gavilanes J.G., Lizarbe M. A. 2001. Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction cell death via apoptosis. Eur. J. Biochem. 268, 2113-2123.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2113-2123
-
-
Olmo, N.1
Turnay, J.2
Gonzalez De Butitrago, G.3
Lopez De Silanes, I.4
Gavilanes, J.G.5
Lizarbe, M.A.6
-
15
-
-
0024585923
-
Ribonuclease inhibitor from pig brain: Purification, characterization, and direct spectrophotometric assay
-
Cho S., Joshi J.G. 1989. Ribonuclease inhibitor from pig brain: purification, characterization, and direct spectrophotometric assay. Anal. Biochem. 176, 175-179.
-
(1989)
Anal. Biochem.
, vol.176
, pp. 175-179
-
-
Cho, S.1
Joshi, J.G.2
-
16
-
-
0037259429
-
RNA cleavage and inhibition of protein synthesis by bleomycin
-
Abraham A.T., Lin J., Newton D.L., Rybak S., Hecht S. 2003. RNA cleavage and inhibition of protein synthesis by bleomycin. Chem. Biol. 10, 45-52.
-
(2003)
Chem. Biol.
, vol.10
, pp. 45-52
-
-
Abraham, A.T.1
Lin, J.2
Newton, D.L.3
Rybak, S.4
Hecht, S.5
-
17
-
-
0036786231
-
Structural and energetic analysis of metal ions essential to SRP signal recognition domain assembly
-
Batey R.T., Doudna J.A. 2002. Structural and energetic analysis of metal ions essential to SRP signal recognition domain assembly. Biochemistry. 41, 11703-11710.
-
(2002)
Biochemistry.
, vol.41
, pp. 11703-11710
-
-
Batey, R.T.1
Doudna, J.A.2
-
18
-
-
0345818258
-
MicroRNAs and cancer
-
McManus M.T. 2003. MicroRNAs and cancer. Semin. Cancer Biol. 13, 253-258.
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 253-258
-
-
McManus, M.T.1
-
19
-
-
0037146606
-
Small RNAs make big splash
-
Couzin J. 2002. Small RNAs make big splash. Science. 298, 2296-2297.
-
(2002)
Science
, vol.298
, pp. 2296-2297
-
-
Couzin, J.1
-
20
-
-
0037407561
-
Onconase and its therapeutic potential
-
Saxena S.K., Shogen K., Ardelt W. 2003. Onconase and its therapeutic potential. Lab. Med. 34, 380-387.
-
(2003)
Lab. Med.
, vol.34
, pp. 380-387
-
-
Saxena, S.K.1
Shogen, K.2
Ardelt, W.3
-
21
-
-
0037177808
-
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family
-
Saxena S.K., Sirdeshmukh R., Ardelt W., Mikulski S.M., Shogen K., Youle R.J. 2003. Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family. J. Biol. Chem. 277, 15142-15146.
-
(2003)
J. Biol. Chem.
, vol.277
, pp. 15142-15146
-
-
Saxena, S.K.1
Sirdeshmukh, R.2
Ardelt, W.3
Mikulski, S.M.4
Shogen, K.5
Youle, R.J.6
-
23
-
-
0041823566
-
Degradation of double-stranded RNA by human pancreatic ribonuclease: Crucial role of noncatalytic basic amino acid residues
-
Sorrentino S., Naddeo M., Russo A., D'Alessio G. 2003. Degradation of double-stranded RNA by human pancreatic ribonuclease: crucial role of noncatalytic basic amino acid residues. Biochemistry. 42, 10182-19190.
-
(2003)
Biochemistry.
, vol.42
, pp. 10182-19190
-
-
Sorrentino, S.1
Naddeo, M.2
Russo, A.3
D'Alessio, G.4
-
24
-
-
1542581581
-
Noncatalytic assembly of ribonuclease III with double-stranded RNA
-
Blaszczyk J., Gan J., Tropea J.E., Court D.L., Waugh D.S., Ji X. 2004. Noncatalytic assembly of ribonuclease III with double-stranded RNA. Structure (Camb). 12, 457-466.
-
(2004)
Structure (Camb)
, vol.12
, pp. 457-466
-
-
Blaszczyk, J.1
Gan, J.2
Tropea, J.E.3
Court, D.L.4
Waugh, D.S.5
Ji, X.6
-
25
-
-
0036829110
-
Increased exposure of anionic phospholipids on the surface of tumor blood vessels
-
Ran S., Downes A., Thorpe P.E. 2002. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res. 62, 6132-6140.
-
(2002)
Cancer Res.
, vol.62
, pp. 6132-6140
-
-
Ran, S.1
Downes, A.2
Thorpe, P.E.3
-
26
-
-
0036891466
-
Phosphatidylserine is a marker of tumor vasculature and potential target for cancer imaging and therapy
-
Ran S., Thorpe P.E. 2002. Phosphatidylserine is a marker of tumor vasculature and potential target for cancer imaging and therapy. Inter. J. Radiat. Oncol. Biol. Phys. 54, 1479-1484.
-
(2002)
Inter. J. Radiat. Oncol. Biol. Phys.
, vol.54
, pp. 1479-1484
-
-
Ran, S.1
Thorpe, P.E.2
-
27
-
-
0037439769
-
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway
-
Haigis M.C., Raines R.T. 2002. Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway. J. Cell Sci. 116, 313-324.
-
(2002)
J. Cell Sci.
, vol.116
, pp. 313-324
-
-
Haigis, M.C.1
Raines, R.T.2
-
28
-
-
0037086474
-
Essential stations in the intracellular pathway of cytotoxic bovine seminal ribonuclease
-
Bracale A., Spalletti-Cernia D., Mastronicola M., Castaldi F., Mannucci R., Nitsch L., D'Alessio G. 2002. Essential stations in the intracellular pathway of cytotoxic bovine seminal ribonuclease. Biochem. J. 362, 553-560.
-
(2002)
Biochem. J.
, vol.362
, pp. 553-560
-
-
Bracale, A.1
Spalletti-Cernia, D.2
Mastronicola, M.3
Castaldi, F.4
Mannucci, R.5
Nitsch, L.6
D'Alessio, G.7
-
29
-
-
0037155852
-
Antiplasmin activity of a peptide that binds to the receptor-binding site of angiogenin
-
Gho Y.S., Yoon W.H., Chae C.B. 2002. Antiplasmin activity of a peptide that binds to the receptor-binding site of angiogenin. J. Biol. Chem. 277, 9690-9694.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9690-9694
-
-
Gho, Y.S.1
Yoon, W.H.2
Chae, C.B.3
-
30
-
-
0036381074
-
Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: The role of dangerous unchaperoned molecules
-
Kourie J.I., Henry C.L. 2002. Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: The role of dangerous unchaperoned molecules. Clin. Exp. Pharmacol. Physiol. 29, 741-753.
-
(2002)
Clin. Exp. Pharmacol. Physiol.
, vol.29
, pp. 741-753
-
-
Kourie, J.I.1
Henry, C.L.2
-
31
-
-
33747338539
-
-
Russian source
-
-
-
-
32
-
-
0030018987
-
Studies on the activity of barnase toxins in vitro and in vivo
-
Prior T.I., Kunwar S., Pastan I. 1996. Studies on the activity of barnase toxins in vitro and in vivo. Bioconjug. Chem. 7, 23-29.
-
(1996)
Bioconjug. Chem.
, vol.7
, pp. 23-29
-
-
Prior, T.I.1
Kunwar, S.2
Pastan, I.3
-
33
-
-
0036902921
-
Biological role of alpha-fetoprotein in cancer: Prospects for anticancer therapy
-
Mizejewski G.T. 2002. Biological role of alpha-fetoprotein in cancer: prospects for anticancer therapy. Expert. Rev. Anticancer Ther. 2, 709-735.
-
(2002)
Expert. Rev. Anticancer Ther.
, vol.2
, pp. 709-735
-
-
Mizejewski, G.T.1
-
34
-
-
0036237495
-
Specifically targeting the CD22 receptor of human B-cell lymphomas with RNA damaging agents: A new generation of therapeutics
-
Hursey M., Newton D.L., Hansen H.J., Ruby D., Goldenberg D.M., Rybak S.M. 2002. Specifically targeting the CD22 receptor of human B-cell lymphomas with RNA damaging agents: a new generation of therapeutics. Leuk. Lymphoma. 43, 953-959.
-
(2002)
Leuk. Lymphoma
, vol.43
, pp. 953-959
-
-
Hursey, M.1
Newton, D.L.2
Hansen, H.J.3
Ruby, D.4
Goldenberg, D.M.5
Rybak, S.M.6
-
35
-
-
0035893923
-
Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma
-
Huhn M., Sasse S., Tur M.K., Matthey B., Scinkothe T., Rybak S.M., Barth S., Engert A. 2001. Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma. Cancer Res. 61, 8737-8742.
-
(2001)
Cancer Res.
, vol.61
, pp. 8737-8742
-
-
Huhn, M.1
Sasse, S.2
Tur, M.K.3
Matthey, B.4
Scinkothe, T.5
Rybak, S.M.6
Barth, S.7
Engert, A.8
-
36
-
-
0037051903
-
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells
-
Di Lorenzo C., Nigro A., Piccoli R., D'Alessio G. 2002. A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. FEBS Lett. 516, 208-212.
-
(2002)
FEBS Lett.
, vol.516
, pp. 208-212
-
-
Di Lorenzo, C.1
Nigro, A.2
Piccoli, R.3
D'Alessio, G.4
-
37
-
-
0033939774
-
Targeting activated lymphocytes with an antirely human immunotoxin analogue: Human pancreatic RNase1-human IL-2 fusion
-
Psarras K., Ueda M., Tanabe M., Kitajima M., Aiso S., Komatsu S., Seno M. 2000. Targeting activated lymphocytes with an antirely human immunotoxin analogue: human pancreatic RNase1-human IL-2 fusion. Cytokine. 12, 786-790.
-
(2000)
Cytokine
, vol.12
, pp. 786-790
-
-
Psarras, K.1
Ueda, M.2
Tanabe, M.3
Kitajima, M.4
Aiso, S.5
Komatsu, S.6
Seno, M.7
-
38
-
-
0032611837
-
Mutations in ras genes in experimental tumor of rodents
-
Sills R.C., Boorman G.A., Neal J.E., Hong H.L., Devereux T.R. 1999. Mutations in ras genes in experimental tumor of rodents. IARC Sci. Publ. 146, 55-86.
-
(1999)
IARC Sci. Publ.
, vol.146
, pp. 55-86
-
-
Sills, R.C.1
Boorman, G.A.2
Neal, J.E.3
Hong, H.L.4
Devereux, T.R.5
-
39
-
-
0033602045
-
Cell cycle-related differences in susceptibility of NIH/3T3 cells to ribonucleases
-
Smith M.R., Newton D.L., Mikulski S.M., Rybak S.M. 1999. Cell cycle-related differences in susceptibility of NIH/3T3 cells to ribonucleases. Exper. Cell. Res. 247, 220-232.
-
(1999)
Exper. Cell. Res.
, vol.247
, pp. 220-232
-
-
Smith, M.R.1
Newton, D.L.2
Mikulski, S.M.3
Rybak, S.M.4
-
40
-
-
0036784623
-
Changing the net charge from negative to positive makes ribonuclease Sa cytotoxic
-
Ilinskaya O.N., Dreyer F., Mitkevich V.A., Shaw K.L., Pace C.N., Makarov A.A. 2002. Changing the net charge from negative to positive makes ribonuclease Sa cytotoxic. Protein Sci. 11, 2522-2525.
-
(2002)
Protein Sci.
, vol.11
, pp. 2522-2525
-
-
Ilinskaya, O.N.1
Dreyer, F.2
Mitkevich, V.A.3
Shaw, K.L.4
Pace, C.N.5
Makarov, A.A.6
-
41
-
-
0033925911
-
Inhibition of ras oncogene: A novel approach to antineoplastic therapy
-
Scharovsky O.G., Rozados V.R., Gervasoni S.I., Matar P. 2000. Inhibition of ras oncogene: a novel approach to antineoplastic therapy. J. Biocliem. Sci. 7, 292-298.
-
(2000)
J. Biocliem. Sci.
, vol.7
, pp. 292-298
-
-
Scharovsky, O.G.1
Rozados, V.R.2
Gervasoni, S.I.3
Matar, P.4
-
42
-
-
0037858858
-
High-throughput screening for ion channel modulators
-
Falconer M., Smith F., Sura-Narvval S., Congrave G., Liu Z., Hayter P., Ciaramella G., Keighley W., Haddock P., Waldron G., Sewing A. 2002. High-throughput screening for ion channel modulators. J. Biomolec. Screen. 7, 460-465.
-
(2002)
J. Biomolec. Screen.
, vol.7
, pp. 460-465
-
-
Falconer, M.1
Smith, F.2
Sura-Narvval, S.3
Congrave, G.4
Liu, Z.5
Hayter, P.6
Ciaramella, G.7
Keighley, W.8
Haddock, P.9
Waldron, G.10
Sewing, A.11
-
43
-
-
0034683225
-
Potassium channel openers prevent beta-amyloid toxicity in bovine vascular endothelial cells
-
Chi X., Sutton E.T., Hellermenn G., Price J.M. 2000. Potassium channel openers prevent beta-amyloid toxicity in bovine vascular endothelial cells. Neurosci. Lett. 290, 9-12.
-
(2000)
Neurosci. Lett.
, vol.290
, pp. 9-12
-
-
Chi, X.1
Sutton, E.T.2
Hellermenn, G.3
Price, J.M.4
-
44
-
-
0347635412
-
Ca channels
-
Ca channels. Biochem. Biophys. Res. Commun. 314, 550-554.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.314
, pp. 550-554
-
-
Ilinskaya, O.1
Koschinski, A.2
Mitkevich, V.3
Repp, H.4
Dreyer, F.5
Pace, N.6
Makarov, A.7
-
45
-
-
0141746349
-
The role of protein stability, solubility, and net charge in amyloid fibril formation
-
Schmittschmitt J.P., Scholtz M. 2003. The role of protein stability, solubility, and net charge in amyloid fibril formation. Protein Sci. 12, 2374-2378.
-
(2003)
Protein Sci.
, vol.12
, pp. 2374-2378
-
-
Schmittschmitt, J.P.1
Scholtz, M.2
-
48
-
-
33747344083
-
-
Russian source
-
-
-
-
50
-
-
0030597957
-
SOS-inducing ability of native and mutant microbial ribonucleases
-
Ilinskaya O.N., Ivanchenko O.B., Karamova N.S., Kipenskaya L.V. 1996. SOS-inducing ability of native and mutant microbial ribonucleases. Mut. Res. 354, 203-209.
-
(1996)
Mut. Res.
, vol.354
, pp. 203-209
-
-
Ilinskaya, O.N.1
Ivanchenko, O.B.2
Karamova, N.S.3
Kipenskaya, L.V.4
-
51
-
-
0029071573
-
Bacterial ribonuclease: Mutagenic effect in microbial test-systems
-
Ilinskaya O.N., Ivanchenko O.B., Karamova N.S. 1995. Bacterial ribonuclease: mutagenic effect in microbial test-systems. Mutagenesis. 10, 165-170.
-
(1995)
Mutagenesis
, vol.10
, pp. 165-170
-
-
Ilinskaya, O.N.1
Ivanchenko, O.B.2
Karamova, N.S.3
-
52
-
-
0030914745
-
Nephrotoxic effects of bacterial ribonucleases in the isolated perfused rat kidney
-
Ilinskaya O.N., Vamvakas S. 1997. Nephrotoxic effects of bacterial ribonucleases in the isolated perfused rat kidney. Toxicology. 120, 55-63.
-
(1997)
Toxicology
, vol.120
, pp. 55-63
-
-
Ilinskaya, O.N.1
Vamvakas, S.2
-
53
-
-
33747329470
-
-
Russian source
-
-
-
-
54
-
-
0034072727
-
Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: Evidence for cytotoxic mechanisms different from inhibition of protein synthesis
-
Iordanov M.S., Ryabinina O.P., Wong J., Newton D.L., Rybak S.M., Magun B.E. 2000. Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis. Cancer Res. 60, 1983-1994.
-
(2000)
Cancer Res.
, vol.60
, pp. 1983-1994
-
-
Iordanov, M.S.1
Ryabinina, O.P.2
Wong, J.3
Newton, D.L.4
Rybak, S.M.5
Magun, B.E.6
-
55
-
-
0035954402
-
Preparation of potent cytotoxic ribonucleases by cationization: Enhanced cellular uptake and decreased interaction with ribonuclease inhibitor by chemical modification of carboxyl groups
-
Futami J., Maeda T., Kitazoe M., Nukui E., Tada H., Seno M., Kosaka M., Yamada H. 2001. Preparation of potent cytotoxic ribonucleases by cationization: enhanced cellular uptake and decreased interaction with ribonuclease inhibitor by chemical modification of carboxyl groups. Biochemistry. 40, 7518-7524.
-
(2001)
Biochemistry
, vol.40
, pp. 7518-7524
-
-
Futami, J.1
Maeda, T.2
Kitazoe, M.3
Nukui, E.4
Tada, H.5
Seno, M.6
Kosaka, M.7
Yamada, H.8
-
56
-
-
0028931427
-
Recombinant human eosinophil cationic protein. Ribonuclease activity is not essential for cytotoxicity
-
Rosenberg H.F. 1995. Recombinant human eosinophil cationic protein. Ribonuclease activity is not essential for cytotoxicity. J. Biol. Chem. 270, 7876-7881.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7876-7881
-
-
Rosenberg, H.F.1
-
58
-
-
0034625439
-
Conformational stability is a determinant of ribonuclease A cytotoxicity
-
Klink T.A., Raines R.T. 2000. Conformational stability is a determinant of ribonuclease A cytotoxicity. J. Biol. Chem. 275, 17463-17467.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17463-17467
-
-
Klink, T.A.1
Raines, R.T.2
-
59
-
-
0034698264
-
A synamorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease
-
Leland P.A., Staniszewski K.E., Kim B.M., Raines R. 2000. A synamorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease. FEBS Lett. 477, 203-207.
-
(2000)
FEBS Lett.
, vol.477
, pp. 203-207
-
-
Leland, P.A.1
Staniszewski, K.E.2
Kim, B.M.3
Raines, R.4
-
60
-
-
0035822616
-
Contribution of chain termini to the conformational stability and biological activity of onconase
-
Notomista E., Catanzano F., Graziano G., Di Gaetano S., Barone G., Di Donato A. 2001. Contribution of chain termini to the conformational stability and biological activity of onconase. Biochemistry. 40, 9097-9103.
-
(2001)
Biochemistry
, vol.40
, pp. 9097-9103
-
-
Notomista, E.1
Catanzano, F.2
Graziano, G.3
Di Gaetano, S.4
Barone, G.5
Di Donato, A.6
-
61
-
-
1642441835
-
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A
-
Matousek J., Pouckova P., Hlouskova D., Zadvinova M., Soucek J., Skvor J. 2004. Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A. J. Contr. Release. 94, 401-410.
-
(2004)
J. Contr. Release
, vol.94
, pp. 401-410
-
-
Matousek, J.1
Pouckova, P.2
Hlouskova, D.3
Zadvinova, M.4
Soucek, J.5
Skvor, J.6
-
62
-
-
1342281681
-
Glycosylation of onconase increases its conformational stability and toxicity for cancer cells
-
Kim B.M., Kim H., Raines R., Lee Y. 2004. Glycosylation of onconase increases its conformational stability and toxicity for cancer cells. Biochem. Biophys. Res. Commun. 315, 976-983.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.315
, pp. 976-983
-
-
Kim, B.M.1
Kim, H.2
Raines, R.3
Lee, Y.4
-
63
-
-
13044251829
-
A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells
-
Piccoli R., Di Gaetano S., De Lorenzo C., Grauso M., Monaco C., Spalletti-Cernia D., Laccetti P., Cinatl J., Matousek J., D'Alessio G. 1999. A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells. Proc. Natl. Acad. Sci. USA. 96, 7768-7773.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7768-7773
-
-
Piccoli, R.1
Di Gaetano, S.2
De Lorenzo, C.3
Grauso, M.4
Monaco, C.5
Spalletti-Cernia, D.6
Laccetti, P.7
Cinatl, J.8
Matousek, J.9
D'Alessio, G.10
-
64
-
-
0842329860
-
Higly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin
-
Spalletti-Cernia D., Sorrentino R., Di Gaetano S., Piccoli R., Santoro V., D'Alessio G., Laccetti P., Vacchio G. 2004. Higly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin. Brit. J. Cancer. Res. 90, 270-277.
-
(2004)
Brit. J. Cancer. Res.
, vol.90
, pp. 270-277
-
-
Spalletti-Cernia, D.1
Sorrentino, R.2
Di Gaetano, S.3
Piccoli, R.4
Santoro, V.5
D'Alessio, G.6
Laccetti, P.7
Vacchio, G.8
-
65
-
-
0038267567
-
Antitumor activity and other biological actions of oligomers of ribonuclease A
-
Matousek J., Gotte G., Pouckova P., Soucek J., Slavik T., Vottariello F., Libonati M. 2003. Antitumor activity and other biological actions of oligomers of ribonuclease A. J. Biol. Chem. 278, 23817-23822.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23817-23822
-
-
Matousek, J.1
Gotte, G.2
Pouckova, P.3
Soucek, J.4
Slavik, T.5
Vottariello, F.6
Libonati, M.7
-
66
-
-
0036684790
-
Optimum modification for the highest cytotoxicity of cationized ribonuclease
-
Futami J., Nukui E., Maeda T., Kosaka M., Tada H., Sano M., Yamada H. 2002. Optimum modification for the highest cytotoxicity of cationized ribonuclease. J. Biochem. (Tokyo). 132, 223-228.
-
(2002)
J. Biochem. (Tokyo)
, vol.132
, pp. 223-228
-
-
Futami, J.1
Nukui, E.2
Maeda, T.3
Kosaka, M.4
Tada, H.5
Sano, M.6
Yamada, H.7
-
67
-
-
0037430969
-
Cytotoxic ribonucleases: Molecular weapons and their targets
-
Makarov A.A., IIinskaya O.N. 2003. Cytotoxic ribonucleases: molecular weapons and their targets. FEBS Lett. 540, 15-20.
-
(2003)
FEBS Lett.
, vol.540
, pp. 15-20
-
-
Makarov, A.A.1
Iiinskaya, O.N.2
-
68
-
-
1442300945
-
A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity
-
Bosch M., Benito A., Ribo M., Puig T., Beaumelle B., Vilanova M. 2004. A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity. Biochemistry. 43, 2167-2177.
-
(2004)
Biochemistry
, vol.43
, pp. 2167-2177
-
-
Bosch, M.1
Benito, A.2
Ribo, M.3
Puig, T.4
Beaumelle, B.5
Vilanova, M.6
-
69
-
-
0034827077
-
Effect of modification of the carboxyl groups of sialic acid binding lectin from bullfrog (Rana catesbiana) oocyte on anti-tumor activity
-
Iwama M., Ogawa Y., Sasaki N., Nitta K., Takajanagi Y., Ohgi K., Tsuji T., Irie M. 2001. Effect of modification of the carboxyl groups of sialic acid binding lectin from bullfrog (Rana catesbiana) oocyte on anti-tumor activity. Biol. Pharm. Bull. 24, 978-981.
-
(2001)
Biol. Pharm. Bull.
, vol.24
, pp. 978-981
-
-
Iwama, M.1
Ogawa, Y.2
Sasaki, N.3
Nitta, K.4
Takajanagi, Y.5
Ohgi, K.6
Tsuji, T.7
Irie, M.8
-
70
-
-
2642567595
-
A novel ribotoxin with ribonuclease activity that specifically cleaves a single phosphodiester bond in rat 28S ribosomal RNA and inactivates ribosome
-
Xu H., He W.J., Liu W.Y. 2004. A novel ribotoxin with ribonuclease activity that specifically cleaves a single phosphodiester bond in rat 28S ribosomal RNA and inactivates ribosome. Arch. Biochem. Biophys. 427, 30-40.
-
(2004)
Arch. Biochem. Biophys.
, vol.427
, pp. 30-40
-
-
Xu, H.1
He, W.J.2
Liu, W.Y.3
-
71
-
-
4043112821
-
Purification and characterization of Moschatin, a novel type I ribosome-inactivated protein from the mature seeds of pumpkin (Cucurbita moschata), and preparation of its immunotoxin against human melanoma cells
-
Xia H.C., Li F., Zhang Z.C. 2003. Purification and characterization of Moschatin, a novel type I ribosome-inactivated protein from the mature seeds of pumpkin (Cucurbita moschata), and preparation of its immunotoxin against human melanoma cells. Cell Research. 13, 369-374.
-
(2003)
Cell Research
, vol.13
, pp. 369-374
-
-
Xia, H.C.1
Li, F.2
Zhang, Z.C.3
-
72
-
-
0036589213
-
The modes of action of colicins E5 and D, and related cytotoxic tRNases
-
Masaki H., Ogawa T. 2002. The modes of action of colicins E5 and D, and related cytotoxic tRNases. Biochimie. 84, 433-438.
-
(2002)
Biochimie
, vol.84
, pp. 433-438
-
-
Masaki, H.1
Ogawa, T.2
-
73
-
-
0036402981
-
Glucine 38 is crutial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA
-
Gaur D., Seth D., Batra J.K. 2002. Glucine 38 is crutial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA. Biochem. Biophys. Res. Commun. 297, 390-395.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 390-395
-
-
Gaur, D.1
Seth, D.2
Batra, J.K.3
-
74
-
-
0031596225
-
G1 arrest of U-937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation
-
Juan G., Ardelt B., Li X., Mikulski S.M., Shogen K., Ardelt W., Mittelman A., Darzynkiewicz Z. 1998. G1 arrest of U-937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation. Leukemia. 12, 1241-1248.
-
(1998)
Leukemia
, vol.12
, pp. 1241-1248
-
-
Juan, G.1
Ardelt, B.2
Li, X.3
Mikulski, S.M.4
Shogen, K.5
Ardelt, W.6
Mittelman, A.7
Darzynkiewicz, Z.8
-
75
-
-
33747352139
-
-
Russian source
-
-
-
-
76
-
-
1642603947
-
A small modulatory dsRNA specifies the fate of adult neural stem cells
-
Kuwabara T., Hsieh J., Nakashima K., Taira K., Gage F.H. 2004. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell. 116, 779-793.
-
(2004)
Cell
, vol.116
, pp. 779-793
-
-
Kuwabara, T.1
Hsieh, J.2
Nakashima, K.3
Taira, K.4
Gage, F.H.5
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