Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A

Journal of Controlled Release

Volumn 94, Issue 2-3, 2004, Pages 401-410

  Matoušek, Josef ^a   Poučková, Pavla ^b   Hloušková, Daniela ^b   Zadinová, Marie ^b   Souček, Josef ^c   Škvor, Jiří ^b  

^a INSTITUTE OF ANIMAL PHYSIOLOGY AND GENETICS   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

Antitumor; Aspermatogenesis; Embryotoxicity; Hyaluronidase; Melanoma; Mice; PEG; Ribonuclease A

Indexed keywords

ANTIBODIES; CELLS; DISEASE CONTROL; ENZYMES; IMMUNOLOGY; POLYETHYLENE GLYCOLS; RNA;

IMMUNOGENICITY;

TUMORS;

ANTINEOPLASTIC AGENT; HYALURONIDASE; MACROGOL; RIBONUCLEASE A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONJUGATION; EPIDIDYMIS; HUMAN; HUMAN CELL; IMMUNOGENICITY; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPERMATOGENESIS; SPERMATOZOON DENSITY; STATISTICAL SIGNIFICANCE; TESTIS;

EID: 1642441835     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2003.10.025     Document Type: Article

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