-
1
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
Green, D. R. Apoptotic pathways: the roads to ruin. Cell, 94: 695-698, 1998.
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
2
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Washington DC
-
Ashkenazi, A., and Dixit, V. M. Death receptors: signaling and modulation. Science (Washington DC), 281: 1305-1308, 1998.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
3
-
-
0032575752
-
Mitochondria and apoptosis
-
Washington DC
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Washington DC), 281: 1309-1312, 1998.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
4
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen, G. M. Caspases: the executioners of apoptosis. Biochem. J., 326; 1-16, 1997.
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
5
-
-
2642689658
-
Proteases to die for
-
Cryns, V., and Yuan, J. Proteases to die for. Genes Dev., 12: 1551-1570, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 1551-1570
-
-
Cryns, V.1
Yuan, J.2
-
6
-
-
0032575750
-
Caspases: Enemies within
-
Washington DC
-
Thornberry, N. A., and Lazebnik, Y. Caspases: enemies within. Science (Washington DC), 281: 1312-1316, 1998.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
7
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell, 85: 817-827, 1996.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
8
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhihitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhihitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc. Natl. Acad. Sci. USA, 93: 14486-14491, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
9
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
Stennicke, H. R., Jurgensmeier, J. M., Shin, H., Deveraux, Q., Wolf, B. B., Yang, X., Zhou, Q., Ellerby, H. M., Ellerhy, L. M., Bredesen, D., Green, D. R., Reed, J. C., Froclich, C. J., and Salvesen, G. S. Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem., 273: 27084-27090, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
Jurgensmeier, J.M.2
Shin, H.3
Deveraux, Q.4
Wolf, B.B.5
Yang, X.6
Zhou, Q.7
Ellerby, H.M.8
Ellerhy, L.M.9
Bredesen, D.10
Green, D.R.11
Reed, J.C.12
Froclich, C.J.13
Salvesen, G.S.14
-
10
-
-
0032548842
-
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHaα1) death signal
-
Martin, D. A., Siegel, R. M., Zheng, L., and Lenardo, M. J. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHaα1) death signal. J. Biol. Chem., 273: 4345-4349, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4345-4349
-
-
Martin, D.A.1
Siegel, R.M.2
Zheng, L.3
Lenardo, M.J.4
-
11
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell. 1: 949-957, 1998.
-
(1998)
Mol. Cell.
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
12
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell, 91: 479-489, 1997.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
13
-
-
0025633802
-
Biogenesis of mitochondrial c-type cytochromes
-
Gonzales, D. H., and Neupert, W. Biogenesis of mitochondrial c-type cytochromes. J. Bioenerg. Biomembr., 22: 753-768, 1990.
-
(1990)
J. Bioenerg. Biomembr.
, vol.22
, pp. 753-768
-
-
Gonzales, D.H.1
Neupert, W.2
-
14
-
-
0032576692
-
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
-
Rosse, T., Olivier, R., Monney, L., Rager, M., Conus, S., Fellay, I., Jansen, B., and Borner, C. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature (Lond.), 391: 496-499, 1998.
-
(1998)
Nature (Lond.)
, vol.391
, pp. 496-499
-
-
Rosse, T.1
Olivier, R.2
Monney, L.3
Rager, M.4
Conus, S.5
Fellay, I.6
Jansen, B.7
Borner, C.8
-
15
-
-
0032571294
-
The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
-
Pastorino, J. G., Chen, S. T., Tafani, M., Snyder, J. W., and Farber, J. L. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J. Biol. Chem., 273: 7770-7775, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7770-7775
-
-
Pastorino, J.G.1
Chen, S.T.2
Tafani, M.3
Snyder, J.W.4
Farber, J.L.5
-
16
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
Jurgensmeier, J. M., Xie, Z., Deveraux, Q., Ellerby, L., Bredesen, D., and Reed, J. C. Bax directly induces release of cytochrome c from isolated mitochondria. Proc. Natl. Acad. Sci. USA. 95: 4997-5002, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
Ellerby, L.4
Bredesen, D.5
Reed, J.C.6
-
17
-
-
0032487583
-
2+ ions
-
2+ ions. J. Cell Biol., 143: 217-224, 1998.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 217-224
-
-
Eskes, R.1
Antonsson, B.2
Osen-Sand, A.3
Montessuit, S.4
Richter, C.5
Sadoul, R.6
Mazzei, G.7
Nichols, A.8
Martinou, J.C.9
-
18
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
Narita, M., Shimizu, S., Ito, T., Chiltenden, T., Lutz, R. J., Matsuda, H., and Tsujimoto, Y. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci. USA, 95: 14681-14686, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chiltenden, T.4
Lutz, R.J.5
Matsuda, H.6
Tsujimoto, Y.7
-
19
-
-
0032585644
-
Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury
-
Saikumar, P., Dong, Z., Patel, Y., Hall, K., Hopfer, U., Weinberg, J. M., and Venkatachalam, M. A. Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury. Oncogene. 17: 3401-3415, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 3401-3415
-
-
Saikumar, P.1
Dong, Z.2
Patel, Y.3
Hall, K.4
Hopfer, U.5
Weinberg, J.M.6
Venkatachalam, M.A.7
-
20
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J. C. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J. Cell Biol., 144: 891-901, 1999.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.C.9
-
21
-
-
0031888955
-
Caspase-activated dnase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. A. caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature (Lond.), 391: 43-50, 1998.
-
(1998)
Nature (Lond.)
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.A.6
-
22
-
-
0032526193
-
Molecular cloning and expression of a cDNA encoding an apoptotic endonuclease DNase-γ
-
Shiokawa, D., and Tanuma, S. Molecular cloning and expression of a cDNA encoding an apoptotic endonuclease DNase-γ. Biochem. J., 332: 713-720, 1998.
-
(1998)
Biochem. J.
, vol.332
, pp. 713-720
-
-
Shiokawa, D.1
Tanuma, S.2
-
23
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem, R., Hakem, A., Duncan, G. S., Henderson, J. T., Woo, M., Soengas, M. S., Elia, A., de la Pompa, J. L., Kagi, D., Khoo, W., Potter, J., Yoshida, R., Kaufman, S. A., Lowe, S. W., Penninger, J. M., and Mak, T. W. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell, 94: 339-352, 1998.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
24
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida, K., Haydar, T. F., Kuan, C. Y., Gu, Y., Taya, C., Karasuyama, H., Su, M. S., Rakic, P., and Flavell, R. A. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell, 94: 325-337, 1998.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.7
Rakic, P.8
Flavell, R.A.9
-
25
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida, H., Kong, Y. Y., Yoshida, R., Elia, A. J., Hakem, A., Hakem, R., Penninger, J. M., and Mak, T. W. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell, 94: 739-750, 1998.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
26
-
-
0032014073
-
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κ B and AP-1
-
Kasibhatla, S., Brunner, T., Genestier, L., Echeverri, F., Mahboubi, A., and Green, D. R. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κ B and AP-1. Mol. Cell. 1: 543-551, 1998.
-
(1998)
Mol. Cell
, vol.1
, pp. 543-551
-
-
Kasibhatla, S.1
Brunner, T.2
Genestier, L.3
Echeverri, F.4
Mahboubi, A.5
Green, D.R.6
-
27
-
-
0029935682
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen, C., Herr, I., Krammer, P. H., and Debatin, K. M. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat. Med., 2: 574-577, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
28
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr, I., Wilhelm, D., Bohler, T., Angel, P., and Debatin, K. M. Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J., 16: 6200-6208, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
29
-
-
0031051042
-
p53: From inductive signal to cellular effect
-
Hansen, R., and Oren, M. p53: from inductive signal to cellular effect. Curr. Opin. Genet. Dev., 7: 46-51, 1997.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 46-51
-
-
Hansen, R.1
Oren, M.2
-
30
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
31
-
-
84990553409
-
Cytostatic and cytotoxic effects of Pannon (P-30 protein), a novel anticancer agent
-
Darzynkiewicz, Z., Carter, S. P., Mikulski, S. M., Ardelt, W. J., and Shogen, K. Cytostatic and cytotoxic effects of Pannon (P-30 Protein), a novel anticancer agent. Cell Tissue Kinet., 21: 169-182, 1988.
-
(1988)
Cell Tissue Kinet.
, vol.21
, pp. 169-182
-
-
Darzynkiewicz, Z.1
Carter, S.P.2
Mikulski, S.M.3
Ardelt, W.J.4
Shogen, K.5
-
32
-
-
0025020007
-
Striking increase of survival of mice bearing M109 Madison carcinoma treated with a novel protein from amphibian embryos
-
Mikulski, S. M., Ardelt, W., Shogen, K., Bernstein, E. H., and Menduke, H. Striking increase of survival of mice bearing M109 Madison carcinoma treated with a novel protein from amphibian embryos. J. Natl. Cancer Inst., 82: 151-153, 1990.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 151-153
-
-
Mikulski, S.M.1
Ardelt, W.2
Shogen, K.3
Bernstein, E.H.4
Menduke, H.5
-
33
-
-
0027256672
-
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
-
Wu, Y., Mikulski, S. M., Ardelt, W., Rybak, S. M., and Youle, R. J. A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity. J. Biol. Chem., 268: 10686-10693, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10686-10693
-
-
Wu, Y.1
Mikulski, S.M.2
Ardelt, W.3
Rybak, S.M.4
Youle, R.J.5
-
34
-
-
0028072567
-
Characterization of the mechanism of cellular and cell free protein synthesis inhibition by an anti-tumor ribonuclease
-
Lin, J. J., Newton, D. L., Mikulski, S. M., Kung, H. F., Youle, R. J., and Rybak, S. M. Characterization of the mechanism of cellular and cell free protein synthesis inhibition by an anti-tumor ribonuclease. Biochem. Biophys. Res. Commun., 204: 156-162, 1994.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.204
, pp. 156-162
-
-
Lin, J.J.1
Newton, D.L.2
Mikulski, S.M.3
Kung, H.F.4
Youle, R.J.5
Rybak, S.M.6
-
35
-
-
15844415446
-
Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease
-
Rybak, S. M., Pearson, J. W., Fogler, W. E., Volker, K., Spence, S. E., Newton, D. L., Mikulski, S. M., Ardelt, W., Riggs, C. W., Kung, H. F., and Longo, D. L. Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease. J. Natl. Cancer Inst., 88: 747-753, 1996.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 747-753
-
-
Rybak, S.M.1
Pearson, J.W.2
Fogler, W.E.3
Volker, K.4
Spence, S.E.5
Newton, D.L.6
Mikulski, S.M.7
Ardelt, W.8
Riggs, C.W.9
Kung, H.F.10
Longo, D.L.11
-
36
-
-
0025960523
-
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases
-
Ardelt, W., Mikulski, S. M., and Shogen, K. Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases. J. Biol. Chem., 266: 245-251, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 245-251
-
-
Ardelt, W.1
Mikulski, S.M.2
Shogen, K.3
-
37
-
-
0030940829
-
From housekeeper to microsurgeon: The diagnostic and therapeutic potential of ribonucleases
-
Schein, C. H. From housekeeper to microsurgeon: the diagnostic and therapeutic potential of ribonucleases. Nat. Biotechnol., 15: 529-536, 1997.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 529-536
-
-
Schein, C.H.1
-
38
-
-
0000601039
-
Onconase and doxorubicin synergy in prolonging survival of MDA-MB-231 human breast cancer-bearing nude mice
-
Mikulski, S. M., Newton, D. L., Wiltrout, R. H., and Rybak, S. M. Onconase and doxorubicin synergy in prolonging survival of MDA-MB-231 human breast cancer-bearing nude mice. Proc. Am. Assoc. Cancer Res. 40: 491, 1999.
-
(1999)
Proc. Am. Assoc. Cancer Res.
, vol.40
, pp. 491
-
-
Mikulski, S.M.1
Newton, D.L.2
Wiltrout, R.H.3
Rybak, S.M.4
-
39
-
-
0025840179
-
Cytotoxic potential of ribonuclease and ribonuclease hybrid proteins
-
Rybak, S. M., Saxena, S. K., Ackerman, E. J., and Youle, R. J. Cytotoxic potential of ribonuclease and ribonuclease hybrid proteins. J. Biol. Chem., 266: 21202-21207, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 21202-21207
-
-
Rybak, S.M.1
Saxena, S.K.2
Ackerman, E.J.3
Youle, R.J.4
-
40
-
-
0032169863
-
Ribonuclease A variants with potent cytotoxic activity
-
Leland, P. A., Schultz, L. W., Kim, B. M., and Raines, R. T. Ribonuclease A variants with potent cytotoxic activity. Proc. Natl. Acad. Sci. USA, 95: 10407-10412, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10407-10412
-
-
Leland, P.A.1
Schultz, L.W.2
Kim, B.M.3
Raines, R.T.4
-
41
-
-
0030973162
-
Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the α-sarcin/ricin loop in the 28S rRNA
-
Iordanov, M. S., Pribnow, D., Magun, J. L., Dinh, T. H., Pearson, J. A., Chen, S. L., and Magun, B. E. Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the α-sarcin/ricin loop in the 28S rRNA. Mol. Cell Biol., 17: 3373-3381, 1997.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 3373-3381
-
-
Iordanov, M.S.1
Pribnow, D.2
Magun, J.L.3
Dinh, T.H.4
Pearson, J.A.5
Chen, S.L.6
Magun, B.E.7
-
42
-
-
0030916745
-
Expression and characterization of a cytotoxic human-frog chimeric ribonuclease: Potential for cancer therapy
-
Newton, D. L., Xue, Y., Boque, L., Wlodawer, A., Kung, H. F., and Rybak, S. M. Expression and characterization of a cytotoxic human-frog chimeric ribonuclease: potential for cancer therapy. Protein Eng., 10: 463-470, 1997.
-
(1997)
Protein Eng.
, vol.10
, pp. 463-470
-
-
Newton, D.L.1
Xue, Y.2
Boque, L.3
Wlodawer, A.4
Kung, H.F.5
Rybak, S.M.6
-
43
-
-
0030914282
-
Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway
-
Goillot, E., Raingeaud, J., Ranger, A., Tepper, R. I., Davis, R. J., Harlow, E., and Sanchez, I. Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proc. Natl. Acad. Sci. USA, 94: 3302-3307, 1997
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3302-3307
-
-
Goillot, E.1
Raingeaud, J.2
Ranger, A.3
Tepper, R.I.4
Davis, R.J.5
Harlow, E.6
Sanchez, I.7
-
44
-
-
0026716402
-
Endothelin induces transcription of fos/jun family genes: A prominent role for calcium ion
-
Pribnow, D., Muldoon, L. L., Fajardo, M., Theodor, L., Chen, L. Y., and Magun, B. E. Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion. Mol. Endocrinol., 6: 1003-1012, 1992.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1003-1012
-
-
Pribnow, D.1
Muldoon, L.L.2
Fajardo, M.3
Theodor, L.4
Chen, L.Y.5
Magun, B.E.6
-
45
-
-
0032546791
-
Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells
-
Iordanov, M. S., Pribnow, D., Magun, J. L., Dinh, T. H., Pearson, J. A., and Magun, B. E. Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells. J. Biol. Chem., 273: 15794-15803, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15794-15803
-
-
Iordanov, M.S.1
Pribnow, D.2
Magun, J.L.3
Dinh, T.H.4
Pearson, J.A.5
Magun, B.E.6
-
46
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J., 17: 37-49, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
47
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature (Lond.), 371: 346-347, 1994.
-
(1994)
Nature (Lond.)
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
48
-
-
0028990125
-
Yama/CPP32 β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. Yama/CPP32 β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81: 801-809, 1995.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
49
-
-
0026344260
-
Analysis of the p53 gene in human uterine carcinoma cell lines
-
Yaginuma, Y., and Westphal, H. Analysis of the p53 gene in human uterine carcinoma cell lines. Cancer Res., 51: 6506-6509, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6506-6509
-
-
Yaginuma, Y.1
Westphal, H.2
-
50
-
-
0027315291
-
Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53
-
Hoppe-Seyler, F., and Butz, K. Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53. J. Virol., 67: 3111-3117, 1993.
-
(1993)
J. Virol.
, vol.67
, pp. 3111-3117
-
-
Hoppe-Seyler, F.1
Butz, K.2
-
51
-
-
0030391262
-
Mechanism of HPV E6 proteins in cellular transformation
-
Huibregtse, J. M., and Beaudenon, S. L. Mechanism of HPV E6 proteins in cellular transformation. Semin. Cancer Biol., 7: 317-326, 1996.
-
(1996)
Semin. Cancer Biol.
, vol.7
, pp. 317-326
-
-
Huibregtse, J.M.1
Beaudenon, S.L.2
-
52
-
-
0030003630
-
Induction of Fas-mediated apoptosis on circulating lymphocytes by surgical stress
-
Oka, M., Hirazawa, K., Yamamoto, K., Iizuka, N., Hazama, S., Suzuki, T., and Kobayashi, N. Induction of Fas-mediated apoptosis on circulating lymphocytes by surgical stress. Ann. Surg., 223: 434-440, 1996.
-
(1996)
Ann. Surg.
, vol.223
, pp. 434-440
-
-
Oka, M.1
Hirazawa, K.2
Yamamoto, K.3
Iizuka, N.4
Hazama, S.5
Suzuki, T.6
Kobayashi, N.7
-
53
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL- 1β and resistant to endotoxic shock
-
Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J., Towne, E., Tracey, D., Wardwell, S., Wei, F-Y. Wong, W., Kamen R., and Seshadri, T. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL- 1β and resistant to endotoxic shock. Cell, 80: 401-411, 1995.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
Towne, E.11
Tracey, D.12
Wardwell, S.13
Wei, F.-Y.14
Wong, W.15
Kamen, R.16
Seshadri, T.17
-
54
-
-
0030641487
-
1L-1β convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms
-
Smith, D. J., McGuire, M. J., Tocci, M. J., and Thiele, D. L. 1L-1β convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms. J. Immunol., 158: 163-170, 1997.
-
(1997)
J. Immunol.
, vol.158
, pp. 163-170
-
-
Smith, D.J.1
McGuire, M.J.2
Tocci, M.J.3
Thiele, D.L.4
-
55
-
-
0031044777
-
Characterization of mice deficient in interleukin-1β converting enzyme
-
Li, P., Allen, H., Banerjee, S., and Seshadri, T. Characterization of mice deficient in interleukin-1β converting enzyme. J. Cell. Biochem., 64: 27-32, 1997.
-
(1997)
J. Cell. Biochem.
, vol.64
, pp. 27-32
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Seshadri, T.4
-
56
-
-
0032568954
-
Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c
-
Kuwana, T., Smith, J. J., Muzio, M., Dixit, V., Newmeyer, D. D., and Kornbluth, S. Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c. J. Biol. Chem., 273: 16589-16594, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16589-16594
-
-
Kuwana, T.1
Smith, J.J.2
Muzio, M.3
Dixit, V.4
Newmeyer, D.D.5
Kornbluth, S.6
-
57
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li, H., Zhu, H., Xu, C. J., and Yuan, J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94: 491-501, 1998.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
58
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell, 94: 481-490, 1998.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
59
-
-
0033579810
-
Mitochondrial release of caspase-2 and -9 during the apoptotic process
-
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Brenner, C., Larochette, N., Prevost, M. C., Alzari, P. M., and Kroemer, G. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J. Exp. Med., 189: 381-394, 1999.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 381-394
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Brenner, C.5
Larochette, N.6
Prevost, M.C.7
Alzari, P.M.8
Kroemer, G.9
-
60
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
Krajewski, S., Krajewska, M., Ellerby, L. M., Welsh, K., Xie, Z., Deveraux, Q. L., Salvesen, G. S., Bredesen, D. E., Rosenthal, R. E., Fiskum, G., and Reed, J. C. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. Proc. Natl. Acad. Sci. USA, 96: 5752-5757, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5752-5757
-
-
Krajewski, S.1
Krajewska, M.2
Ellerby, L.M.3
Welsh, K.4
Xie, Z.5
Deveraux, Q.L.6
Salvesen, G.S.7
Bredesen, D.E.8
Rosenthal, R.E.9
Fiskum, G.10
Reed, J.C.11
-
61
-
-
0026468508
-
Therapeutic potential of capsaicin-like molecules: Studies in animals and humans
-
Maggi, C. A. Therapeutic potential of capsaicin-like molecules: studies in animals and humans. Life Sci., 51: 1777-1781, 1992.
-
(1992)
Life Sci.
, vol.51
, pp. 1777-1781
-
-
Maggi, C.A.1
-
62
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., and Julius, D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (Lond.), 389: 816-824, 1997.
-
(1997)
Nature (Lond.)
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
63
-
-
0031667074
-
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor
-
Mikulski, S. M., Viera, A., Deptala, A., and Darzynkiewicz, Z. Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor. Int. J. Oncol., 13: 633-644, 1998.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 633-644
-
-
Mikulski, S.M.1
Viera, A.2
Deptala, A.3
Darzynkiewicz, Z.4
-
64
-
-
0031861178
-
Potentiation of tumor necrosis factor induced apoptosis by onconase
-
Deptala, A., Halicka, H. D., Ardelt, B., Ardelt, W., Mikulski, S. M., Shogen, K., and Darzynkiewicz, Z. Potentiation of tumor necrosis factor induced apoptosis by onconase. Int. J. Oncol., 13: 11-16, 1998.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 11-16
-
-
Deptala, A.1
Halicka, H.D.2
Ardelt, B.3
Ardelt, W.4
Mikulski, S.M.5
Shogen, K.6
Darzynkiewicz, Z.7
-
65
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
Kroemer, G., Dallaporta, B., and Resche-Rigon, M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol., 60: 619-642, 1998.
-
(1998)
Annu. Rev. Physiol.
, vol.60
, pp. 619-642
-
-
Kroemer, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
66
-
-
0032394928
-
Role of caspases in immunotoxin-induced apoptosis of cancer cells
-
Keppler-Hafkemeyer, A., Brinkmann, U., and Pastan, I. Role of caspases in immunotoxin-induced apoptosis of cancer cells. Biochemistry, 37: 16934-16942, 1998.
-
(1998)
Biochemistry
, vol.37
, pp. 16934-16942
-
-
Keppler-Hafkemeyer, A.1
Brinkmann, U.2
Pastan, I.3
-
67
-
-
0030035584
-
p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas
-
Benhattar, J., Cerottini, J. P., Saraga, E., Metthez, G., and Givel, J. C. p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int. J. Cancer, 69: 190-192, 1996.
-
(1996)
Int. J. Cancer
, vol.69
, pp. 190-192
-
-
Benhattar, J.1
Cerottini, J.P.2
Saraga, E.3
Metthez, G.4
Givel, J.C.5
-
68
-
-
0030036839
-
Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas
-
Iwadate, Y., Fujimoto, S., Tagawa, M., Namba, H., Sueyoshi, K., Hirose, M., and Sakiyama, S. Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas. Int. J. Cancer, 69: 236-240, 1996.
-
(1996)
Int. J. Cancer
, vol.69
, pp. 236-240
-
-
Iwadate, Y.1
Fujimoto, S.2
Tagawa, M.3
Namba, H.4
Sueyoshi, K.5
Hirose, M.6
Sakiyama, S.7
|