-
1
-
-
4243602211
-
Global epidemiology of sexually transmitted diseases
-
Gerbase, A. C., J. T. Rowley, and T. E. Mertens. 1998. Global epidemiology of sexually transmitted diseases. Lancet 351(Suppl. 3): 2-4.
-
(1998)
Lancet
, vol.351
, Issue.SUPPL. 3
, pp. 2-4
-
-
Gerbase, A.C.1
Rowley, J.T.2
Mertens, T.E.3
-
2
-
-
0021246150
-
Infertility as a consequence of chlamydial infection of the upper genital tract in female mice
-
Swenson, C. E., and J. Schachter. 1984. Infertility as a consequence of chlamydial infection of the upper genital tract in female mice. Sex. Transm. Dis. 11: 64-67.
-
(1984)
Sex. Transm. Dis.
, vol.11
, pp. 64-67
-
-
Swenson, C.E.1
Schachter, J.2
-
3
-
-
0028967628
-
Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis
-
Cain, T. K., and R. G. Rank. 1995. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect. Immun. 63: 1784-1789.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1784-1789
-
-
Cain, T.K.1
Rank, R.G.2
-
4
-
-
0026011410
-
Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines
-
Ramsey, K. H., and R. G. Rank. 1991. Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines. Infect. Immun. 59: 925-931.
-
(1991)
Infect. Immun.
, vol.59
, pp. 925-931
-
-
Ramsey, K.H.1
Rank, R.G.2
-
5
-
-
0026660316
-
Effect of γ interferon on resolution of murine chlamydial genital infection
-
Rank, R. G., K. H. Ramsey, E. A. Pack, and D. M. Williams. 1992. Effect of γ interferon on resolution of murine chlamydial genital infection. Infect. Immun. 60: 4427-4429.
-
(1992)
Infect. Immun.
, vol.60
, pp. 4427-4429
-
-
Rank, R.G.1
Ramsey, K.H.2
Pack, E.A.3
Williams, D.M.4
-
6
-
-
0031112653
-
Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways
-
Perry, L. L., K. Feilzer, and H. D. Caldwell. 1997. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways. J. Immunol. 158: 3344-3352.
-
(1997)
J. Immunol.
, vol.158
, pp. 3344-3352
-
-
Perry, L.L.1
Feilzer, K.2
Caldwell, H.D.3
-
7
-
-
0030988438
-
Dissemination of Chlamydia trachomatis chronic genital tract infection in γ interferon gene knockout mice
-
Cotter, T. W., K. H. Ramsey, G. S. Miranpuri, C. E. Poulsen, and G. I. Byrne. 1997. Dissemination of Chlamydia trachomatis chronic genital tract infection in γ interferon gene knockout mice. Infect. Immun. 65: 2145-2152.
-
(1997)
Infect. Immun.
, vol.65
, pp. 2145-2152
-
-
Cotter, T.W.1
Ramsey, K.H.2
Miranpuri, G.S.3
Poulsen, C.E.4
Byrne, G.I.5
-
9
-
-
0036232737
-
Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells
-
Spitzer, J. H., A. Visintin, A. Mazzoni, M. N. Kennedy, and D. M. Segal. 2002. Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells. Eur. J. Immunol. 32: 1182-1187.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1182-1187
-
-
Spitzer, J.H.1
Visintin, A.2
Mazzoni, A.3
Kennedy, M.N.4
Segal, D.M.5
-
10
-
-
3042640509
-
Expression of Toll-like receptors on human platelets
-
Shiraki, R., N. Inoue, S. Kawasaki, A. Takei, M. Kadotani, Y. Ohnishi, J. Ejiri, S. Kobayashi, K. Hirata, S. Kawashima, and M. Yokoyama. 2004. Expression of Toll-like receptors on human platelets. Thromb. Res. 113: 379-385.
-
(2004)
Thromb. Res.
, vol.113
, pp. 379-385
-
-
Shiraki, R.1
Inoue, N.2
Kawasaki, S.3
Takei, A.4
Kadotani, M.5
Ohnishi, Y.6
Ejiri, J.7
Kobayashi, S.8
Hirata, K.9
Kawashima, S.10
Yokoyama, M.11
-
11
-
-
0038242875
-
Toll-like receptor signaling pathways
-
Barton, G. M., and R. Medzhitov. 2003. Toll-like receptor signaling pathways. Science 300: 1524-1525.
-
(2003)
Science
, vol.300
, pp. 1524-1525
-
-
Barton, G.M.1
Medzhitov, R.2
-
12
-
-
0344585387
-
Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection
-
Darville, T., J. M. O'Neill, C. W. Andrews, Jr., U. M. Nagarajan, L. Stahl, and D. M. Ojcius. 2003. Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J. Immunol. 171: 6187-6197.
-
(2003)
J. Immunol.
, vol.171
, pp. 6187-6197
-
-
Darville, T.1
O'Neill, J.M.2
Andrews Jr., C.W.3
Nagarajan, U.M.4
Stahl, L.5
Ojcius, D.M.6
-
13
-
-
0029162732
-
+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract
-
+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect. Immun. 63: 3302-3308.
-
(1995)
Infect. Immun.
, vol.63
, pp. 3302-3308
-
-
Su, H.1
Caldwell, H.D.2
-
14
-
-
0028805751
-
Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection
-
Morrison, R. P., K. Feilzer, and D. B. Tumas. 1995. Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection. Infect. Immun. 63: 4661-4668.
-
(1995)
Infect. Immun.
, vol.63
, pp. 4661-4668
-
-
Morrison, R.P.1
Feilzer, K.2
Tumas, D.B.3
-
15
-
-
0036533663
-
IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
-
Dufour, J. H., M. Dziejman, M. T. Liu, J. H. Leung, T. E. Lane, and A. D. Luster. 2002. IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J. Immunol. 168: 3195-3204.
-
(2002)
J. Immunol.
, vol.168
, pp. 3195-3204
-
-
Dufour, J.H.1
Dziejman, M.2
Liu, M.T.3
Leung, J.H.4
Lane, T.E.5
Luster, A.D.6
-
16
-
-
0027509545
-
Expression of IP-10, a lipopolysaccharide- and interferon-γ- inducible protein, in murine mesangial cells in culture
-
Gomez-Chiarri, M., T. A. Hamilton, J. Egido, and S. N. Emancipator. 1993. Expression of IP-10, a lipopolysaccharide- and interferon-γ-inducible protein, in murine mesangial cells in culture. Am. J. Pathol. 142: 433-439.
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 433-439
-
-
Gomez-Chiarri, M.1
Hamilton, T.A.2
Egido, J.3
Emancipator, S.N.4
-
17
-
-
0027523467
-
Cooperative interaction between interferon (IFN) stimulus response element and κB sequence motifs controls IFNγ- and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter
-
Ohmori, Y., and T. A. Hamilton. 1993. Cooperative interaction between interferon (IFN) stimulus response element and κB sequence motifs controls IFNγ- and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter. J. Biol. Chem. 268: 6677-6688.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6677-6688
-
-
Ohmori, Y.1
Hamilton, T.A.2
-
18
-
-
0242412154
-
Timing of IFN-β exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: A role for IFN-β-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation
-
Nagai, T., O. Devergne, T. F. Mueller, D. L. Perkins, J. M. van Seventer, and G. A. van Seventer. 2003. Timing of IFN-β exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-β-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation. J. Immunol. 171: 5233-5243.
-
(2003)
J. Immunol.
, vol.171
, pp. 5233-5243
-
-
Nagai, T.1
Devergne, O.2
Mueller, T.F.3
Perkins, D.L.4
Van Seventer, J.M.5
Van Seventer, G.A.6
-
19
-
-
3142737286
-
Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages
-
Punturieri, A., R. S. Alviani, T. Polak, P. Copper, J. Sonstein, and J. L. Curtis. 2004. Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages. J. Immunol. 173: 1033-1042.
-
(2004)
J. Immunol.
, vol.173
, pp. 1033-1042
-
-
Punturieri, A.1
Alviani, R.S.2
Polak, T.3
Copper, P.4
Sonstein, J.5
Curtis, J.L.6
-
20
-
-
0036178098
-
Chemokine expression patterns differ within anatomically distinct regions of the genital tract during Chlamydia trachomatis infection
-
Maxion, H. K., and K. A. Kelly. 2002. Chemokine expression patterns differ within anatomically distinct regions of the genital tract during Chlamydia trachomatis infection. Infect. Immun. 70: 1538-1546.
-
(2002)
Infect. Immun.
, vol.70
, pp. 1538-1546
-
-
Maxion, H.K.1
Kelly, K.A.2
-
21
-
-
0034967215
-
Expression of genes encoding Th1 cell-activating cytokines and lymphoid homing chemokines by Chlamydia-pulsed dendritic cells correlates with protective immunizing efficacy
-
Shaw, J. H., V. R. Grund, L. Durling, and H. D. Caldwell. 2001. Expression of genes encoding Th1 cell-activating cytokines and lymphoid homing chemokines by Chlamydia-pulsed dendritic cells correlates with protective immunizing efficacy. Infect. Immun. 69: 4667-4672.
-
(2001)
Infect. Immun.
, vol.69
, pp. 4667-4672
-
-
Shaw, J.H.1
Grund, V.R.2
Durling, L.3
Caldwell, H.D.4
-
22
-
-
3042542185
-
Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin- 12-p70 secretion
-
Johnson, R. M. 2004. Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin- 12-p70 secretion. Infect. Immun. 72: 3951-3960.
-
(2004)
Infect. Immun.
, vol.72
, pp. 3951-3960
-
-
Johnson, R.M.1
-
23
-
-
0029847259
-
Induction of α/β interferon and dependent nitric oxide synthesis during Chlamydia trachomatis infection of McCoy cells in the absence of exogenous cytokine
-
Devitt, A., P. A. Lund, A. G. Morris, and J. H. Pearce. 1996. Induction of α/β interferon and dependent nitric oxide synthesis during Chlamydia trachomatis infection of McCoy cells in the absence of exogenous cytokine. Infect. Immun. 64: 3951-3956.
-
(1996)
Infect. Immun.
, vol.64
, pp. 3951-3956
-
-
Devitt, A.1
Lund, P.A.2
Morris, A.G.3
Pearce, J.H.4
-
24
-
-
0141670818
-
The interferon in TLR signaling: More than just antiviral
-
Hertzog, P. J., L. A. O'Neill, and J. A. Hamilton. 2003. The interferon in TLR signaling: more than just antiviral. Trends Immunol. 24: 534-539.
-
(2003)
Trends Immunol.
, vol.24
, pp. 534-539
-
-
Hertzog, P.J.1
O'Neill, L.A.2
Hamilton, J.A.3
-
25
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-β-induced STAT1α/β- dependent gene expression in macrophages
-
Toshchakov, V., B. W. Jones, P. Y. Perera, K. Thomas, M. J. Cody, S. Zhang, B. R. Williams, J. Major, T. A. Hamilton, M. J. Fenton, and S. N. Vogel. 2002. TLR4, but not TLR2, mediates IFN-β-induced STAT1α/β- dependent gene expression in macrophages. Nat. Immunol. 3: 392-398.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
26
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta, K., P. Georgel, E. Janssen, X. Du, K. Hoebe, K. Crozat, S. Mudd, L. Shamel, S. Sovath, J. Goode, et al. 2004. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc. Natl. Acad. Sci. USA 101: 3516-3521.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
Du, X.4
Hoebe, K.5
Crozat, K.6
Mudd, S.7
Shamel, L.8
Sovath, S.9
Goode, J.10
-
27
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
28
-
-
0037443644
-
The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
-
Hemmi, H., T. Kaisho, K. Takeda, and S. Akira. 2003. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170: 3059-3064.
-
(2003)
J. Immunol.
, vol.170
, pp. 3059-3064
-
-
Hemmi, H.1
Kaisho, T.2
Takeda, K.3
Akira, S.4
-
29
-
-
2342441717
-
LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins
-
Hoebe, K., and B. Beutler. 2004. LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins. J Endotoxin Res. 10: 130-136.
-
(2004)
J Endotoxin Res.
, vol.10
, pp. 130-136
-
-
Hoebe, K.1
Beutler, B.2
-
30
-
-
3042647375
-
Differential requirement for TANK-binding kinase-1 in type 1 interferon responses to toll-like receptor activation and viral infection
-
Perry, A. K., E. K. Chow, J. B. Goodnough, W. C. Yeh, and G. Cheng. 2004. Differential requirement for TANK-binding kinase-1 in type 1 interferon responses to toll-like receptor activation and viral infection. J. Exp. Med. 199: 1651-1658.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1651-1658
-
-
Perry, A.K.1
Chow, E.K.2
Goodnough, J.B.3
Yeh, W.C.4
Cheng, G.5
-
31
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai, T., O. Takeuchi, T. Fujita, J. Inoue, P. F. Muhlradt, S. Sato, K. Hoshino, and S. Akira. 2001. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167: 5887-5894.
-
(2001)
J. Immunol.
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
32
-
-
7944220803
-
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
-
Travassos, L. H., S. E. Girardin, D. J. Philpott, D. Blanot, M. A. Nahori, C. Werts, and I. G. Boneca. 2004. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep. 5: 1000-1006.
-
(2004)
EMBO Rep.
, vol.5
, pp. 1000-1006
-
-
Travassos, L.H.1
Girardin, S.E.2
Philpott, D.J.3
Blanot, D.4
Nahori, M.A.5
Werts, C.6
Boneca, I.G.7
-
33
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11: 443-451.
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
34
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
-
Adachi, O., T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira. 1998. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9: 143-150.
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
35
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
36
-
-
14044253038
-
Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88
-
Fremond, C. M., V. Yeremeev, D. M. Nicolle, M. Jacobs, V. F. Quesniaux, and B. Ryffel. 2004. Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. J. Clin. Invest. 114: 1790-1799.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1790-1799
-
-
Fremond, C.M.1
Yeremeev, V.2
Nicolle, D.M.3
Jacobs, M.4
Quesniaux, V.F.5
Ryffel, B.6
-
37
-
-
0034665047
-
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription
-
Bonnard, M., C. Mirtsos, S. Suzuki, K. Graham, J. Huang, M. Ng, A. Itie, A. Wakeham, A. Shahinian, W. J. Henzel, et al. 2000. Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription. EMBO J. 19: 4976-4985.
-
(2000)
EMBO J.
, vol.19
, pp. 4976-4985
-
-
Bonnard, M.1
Mirtsos, C.2
Suzuki, S.3
Graham, K.4
Huang, J.5
Ng, M.6
Itie, A.7
Wakeham, A.8
Shahinian, A.9
Henzel, W.J.10
-
38
-
-
0032953638
-
Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms
-
Everett, K. D., R. M. Bush, and A. A. Andersen. 1999. Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int. J. Syst. Bacteriol. 49: 415-440.
-
(1999)
Int. J. Syst. Bacteriol.
, vol.49
, pp. 415-440
-
-
Everett, K.D.1
Bush, R.M.2
Andersen, A.A.3
-
40
-
-
0031951332
-
Inducible nitric oxide synthase does not affect resolution of murine chlamydial genital tract infections or eradication of chlamydiae in primary murine cell culture
-
Ramsey, K. H., G. S. Miranpuri, C. E. Poulsen, N. B. Marthakis, L. M. Braune, and G. I. Byrne. 1998. Inducible nitric oxide synthase does not affect resolution of murine chlamydial genital tract infections or eradication of chlamydiae in primary murine cell culture. Infect. Immun. 66: 835-838.
-
(1998)
Infect. Immun.
, vol.66
, pp. 835-838
-
-
Ramsey, K.H.1
Miranpuri, G.S.2
Poulsen, C.E.3
Marthakis, N.B.4
Braune, L.M.5
Byrne, G.I.6
-
41
-
-
0019514724
-
Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis
-
Caldwell, H. D., J. Kromhout, and J. Schachter. 1981. Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis. Infect. Immun. 31: 1161-1176.
-
(1981)
Infect. Immun.
, vol.31
, pp. 1161-1176
-
-
Caldwell, H.D.1
Kromhout, J.2
Schachter, J.3
-
42
-
-
2942731615
-
A hierarchy of nuclear localization signals governs the import of the regulatory factor X complex subunits and MHC class II expression
-
Nagarajan, U. M., A. B. Long, M. T. Harreman, A. H. Corbett, and J. M. Boss. 2004. A hierarchy of nuclear localization signals governs the import of the regulatory factor X complex subunits and MHC class II expression. J. Immunol. 173: 410-419.
-
(2004)
J. Immunol.
, vol.173
, pp. 410-419
-
-
Nagarajan, U.M.1
Long, A.B.2
Harreman, M.T.3
Corbett, A.H.4
Boss, J.M.5
-
43
-
-
0034655297
-
Methylation of class II trans-activator promoter IV: A novel mechanism of MHC class II gene control
-
Morris, A. C., W. E. Spangler, and J. M. Boss. 2000. Methylation of class II trans-activator promoter IV: a novel mechanism of MHC class II gene control. J. Immunol. 164: 4143-4149.
-
(2000)
J. Immunol.
, vol.164
, pp. 4143-4149
-
-
Morris, A.C.1
Spangler, W.E.2
Boss, J.M.3
-
44
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162: 3749-3752.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
45
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe, K., X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, et al. 2003. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424: 743-748.
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
-
46
-
-
0034123135
-
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio, M., D. Bosisio, N. Polentarutti, G. D'Amico, A. Stoppacciaro, R. Mancinelli, C. van't Veer, G. Penton-Rol, L. P. Ruco, P. Allavena, and A. Mantovani. 2000. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J. Immunol. 164: 5998-6004.
-
(2000)
J. Immunol.
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
D'Amico, G.4
Stoppacciaro, A.5
Mancinelli, R.6
Van't Veer, C.7
Penton-Rol, G.8
Ruco, L.P.9
Allavena, P.10
Mantovani, A.11
-
47
-
-
2442446195
-
Intracellular bacterial infection-induced IFN-γ is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-α β-STAT1 signaling
-
Rothfuchs, A. G., C. Trumstedt, H. Wigzell, and M. E. Rottenberg. 2004. Intracellular bacterial infection-induced IFN-γ is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-α β-STAT1 signaling. J. Immunol. 172: 6345-6353.
-
(2004)
J. Immunol.
, vol.172
, pp. 6345-6353
-
-
Rothfuchs, A.G.1
Trumstedt, C.2
Wigzell, H.3
Rottenberg, M.E.4
-
48
-
-
0027978428
-
Interactions between macrophages and chlamydiae
-
La Verda, D., and G. I. Byrne. 1994. Interactions between macrophages and chlamydiae. Immunol. Ser. 60: 381-399.
-
(1994)
Immunol. Ser.
, vol.60
, pp. 381-399
-
-
La Verda, D.1
Byrne, G.I.2
-
49
-
-
0036448929
-
MyD88 as a bottle neck in Toll/IL-1 signaling
-
Takeuchi, O., and S. Akira. 2002. MyD88 as a bottle neck in Toll/IL-1 signaling. Curr. Top. Microbiol. Immunol. 270: 155-167.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.270
, pp. 155-167
-
-
Takeuchi, O.1
Akira, S.2
-
50
-
-
0842300367
-
Inhibitory effect of Toll-like receptor 4 on fusion between phagosomes and endosomes/lysosomes in macrophages
-
Shiratsuchi, A., I. Watanabe, O. Takeuchi, S. Akira, and Y. Nakanishi. 2004. Inhibitory effect of Toll-like receptor 4 on fusion between phagosomes and endosomes/lysosomes in macrophages. J. Immunol. 172: 2039-2047.
-
(2004)
J. Immunol.
, vol.172
, pp. 2039-2047
-
-
Shiratsuchi, A.1
Watanabe, I.2
Takeuchi, O.3
Akira, S.4
Nakanishi, Y.5
-
51
-
-
0242391997
-
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil, F., P. Ahmad-Nejad, H, Hemmi, H. Hochrein, F. Ampenberger, T. Gellert, H. Dietrich, G. Lipford, K. Takeda, S. Akira, et al. 2003. The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur. J. Immunol. 33: 2987-2997.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
Hochrein, H.4
Ampenberger, F.5
Gellert, T.6
Dietrich, H.7
Lipford, G.8
Takeda, K.9
Akira, S.10
-
52
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz, E., A. Schoenemeyer, A. Visintin, K. A. Fitzgerald, B. G. Monks, C. F. Knetter, E. Lien, N. J. Nilsen, T. Espevik, and D. T. Golenbock. 2004. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 5: 190-198.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
Lien, E.7
Nilsen, N.J.8
Espevik, T.9
Golenbock, D.T.10
-
55
-
-
0345827590
-
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
-
McWhirter, S. M., K. A. Fitzgerald, J. Rosains, D. C. Rowe, D. T. Golenbock, and T. Maniatis. 2004. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc. Natl. Acad. Sci. USA 101: 233-238.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 233-238
-
-
McWhirter, S.M.1
Fitzgerald, K.A.2
Rosains, J.3
Rowe, D.C.4
Golenbock, D.T.5
Maniatis, T.6
-
56
-
-
0038393016
-
IKKε and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald, K. A., S. M. McWhirter, K. L. Faia, D. C. Rowe, E. Latz, D. T. Golenbock, A. J. Coyle, S. M. Liao, and T. Maniatis. 2003. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4: 491-496.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
57
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle, S., S. Vaidya, R. O'Connell, H. Dadgostar, P. Dempsey, T. Wu, G. Rao, R. Sun, M. Haberland, R. Modlin, and G. Cheng. 2002. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17: 251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
Cheng, G.11
-
58
-
-
7444250116
-
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
-
Honda, K., H. Yanai, T. Mizutani, H. Negishi, N. Shimada, N. Suzuki, Y. Ohba, A. Takaoka, W. C. Yeh, and T. Taniguchi. 2004. Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. Proc. Natl. Acad. Sci. USA 101: 15416-15421.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15416-15421
-
-
Honda, K.1
Yanai, H.2
Mizutani, T.3
Negishi, H.4
Shimada, N.5
Suzuki, N.6
Ohba, Y.7
Takaoka, A.8
Yeh, W.C.9
Taniguchi, T.10
-
59
-
-
7044253299
-
The infecting dose of Chlamydia muridarum modulates the innate immune response and ascending infection
-
Maxion, H. K., W. Liu, M. H. Chang, and K. A. Kelly. 2004. The infecting dose of Chlamydia muridarum modulates the innate immune response and ascending infection. Infect. Immun. 72: 6330-6340.
-
(2004)
Infect. Immun.
, vol.72
, pp. 6330-6340
-
-
Maxion, H.K.1
Liu, W.2
Chang, M.H.3
Kelly, K.A.4
-
60
-
-
0036151258
-
Chemokine and chemokine receptor dynamics during genital chlamydial infection
-
Belay, T., F. O. Eko, G. A. Ananaba, S. Bowers, T. Moore, D. Lyn, and J. U. Igietseme. 2002. Chemokine and chemokine receptor dynamics during genital chlamydial infection. Infect. Immun. 70: 844-850.
-
(2002)
Infect. Immun.
, vol.70
, pp. 844-850
-
-
Belay, T.1
Eko, F.O.2
Ananaba, G.A.3
Bowers, S.4
Moore, T.5
Lyn, D.6
Igietseme, J.U.7
-
61
-
-
21244445517
-
Mounting of adaptive and innate immunity against Chlamydia trachomatis is CXCR3-dependent
-
J. Oak, ed. University of Szeged, Szeged, Hungary
-
Maxion, H. K., and K. A. Kelly. 2004. Mounting of adaptive and innate immunity against Chlamydia trachomatis is CXCR3-dependent. In Proceedings of 5th Meeting of the European Society of Chlamydial Research. J. Oak, ed. University of Szeged, Szeged, Hungary, p. 155.
-
(2004)
Proceedings of 5th Meeting of the European Society of Chlamydial Research
, pp. 155
-
-
Maxion, H.K.1
Kelly, K.A.2
-
62
-
-
0035885168
-
Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells
-
Prebeck, S., C. Kirschning, S. Durr, C. da Costa, B. Donath, K. Brand, V. Redecke, H. Wagner, and T. Miethke. 2001. Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells. J. Immunol. 167: 3316-3323.
-
(2001)
J. Immunol.
, vol.167
, pp. 3316-3323
-
-
Prebeck, S.1
Kirschning, C.2
Durr, S.3
Da Costa, C.4
Donath, B.5
Brand, K.6
Redecke, V.7
Wagner, H.8
Miethke, T.9
-
63
-
-
0036236691
-
Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways
-
Netea, M. G., B. J. Kullberg, J. M. Galama, A. F. Stalenhoef, C. A. Dinarello, and J. W. Van der Meer. 2002. Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways. Eur. J. Immunol. 32: 1188-1195.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1188-1195
-
-
Netea, M.G.1
Kullberg, B.J.2
Galama, J.M.3
Stalenhoef, A.F.4
Dinarello, C.A.5
Van Der Meer, J.W.6
-
64
-
-
0035800883
-
Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation
-
Sasu, S., D. LaVerda, N. Qureshi, D. T. Golenbock, and D. Beasley. 2001. Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation. Circ. Res. 89: 244-250.
-
(2001)
Circ. Res.
, vol.89
, pp. 244-250
-
-
Sasu, S.1
Laverda, D.2
Qureshi, N.3
Golenbock, D.T.4
Beasley, D.5
-
65
-
-
0141923688
-
A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages
-
Haase, R., C. J. Kirschning, A. Sing, P. Schrottner, K. Fukase, S. Kusumoto, H. Wagner, J. Heesemann, and K. Ruckdeschel. 2003. A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages. J. Immunol. 171: 4294-4303.
-
(2003)
J. Immunol.
, vol.171
, pp. 4294-4303
-
-
Haase, R.1
Kirschning, C.J.2
Sing, A.3
Schrottner, P.4
Fukase, K.5
Kusumoto, S.6
Wagner, H.7
Heesemann, J.8
Ruckdeschel, K.9
-
66
-
-
1642617628
-
The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
-
Hsu, L. C., J. M. Park, K. Zhang, J. L. Luo, S. Maeda, R. J. Kaufman, L. Eckmann, D. G. Guiney, and M. Karin. 2004. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature 428: 341-345.
-
(2004)
Nature
, vol.428
, pp. 341-345
-
-
Hsu, L.C.1
Park, J.M.2
Zhang, K.3
Luo, J.L.4
Maeda, S.5
Kaufman, R.J.6
Eckmann, L.7
Guiney, D.G.8
Karin, M.9
-
67
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki, N., S. Ho, S. Antonenko, R. W. Malefyt, R. A. Kastelein, F. Bazan, and Y. J. Liu, 2001. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194: 863-869.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
Malefyt, R.W.4
Kastelein, R.A.5
Bazan, F.6
Liu, Y.J.7
-
68
-
-
0034777579
-
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
-
Krug, A., A. Towarowski, S. Britsch, S. Rothenfusser, V. Hornung, R. Bals, T. Giese, H. Engelmann, S. Endres, A. M. Krieg, and G. Hartmann. 2001. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur. J. Immunol. 31: 3026-3037.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 3026-3037
-
-
Krug, A.1
Towarowski, A.2
Britsch, S.3
Rothenfusser, S.4
Hornung, V.5
Bals, R.6
Giese, T.7
Engelmann, H.8
Endres, S.9
Krieg, A.M.10
Hartmann, G.11
-
69
-
-
0037108761
-
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway
-
O'Riordan, M., C. H. Yi, R. Gonzales, K. D. Lee, and D. A. Portnoy. 2002. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. USA 99: 13861-13866.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13861-13866
-
-
O'Riordan, M.1
Yi, C.H.2
Gonzales, R.3
Lee, K.D.4
Portnoy, D.A.5
-
70
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M., M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, and T. Fujita. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5: 730-737.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
71
-
-
0036931906
-
The natural alliance between type I interferon and dendritic cells and its role in linking innate and adaptive immunity
-
Santini, S. M., T. Di Pucchio, C. Lapenta, S. Parlato, M. Logozzi, and F. Belardelli. 2002. The natural alliance between type I interferon and dendritic cells and its role in linking innate and adaptive immunity. J. Interferon Cytokine Res. 22: 1071-1080.
-
(2002)
J. Interferon Cytokine Res.
, vol.22
, pp. 1071-1080
-
-
Santini, S.M.1
Di Pucchio, T.2
Lapenta, C.3
Parlato, S.4
Logozzi, M.5
Belardelli, F.6
-
72
-
-
10344252795
-
IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism
-
Stockinger, S., B. Reutterer, B. Schaljo, C. Schellack, S. Brunner, T. Materna, M. Yamamoto, S. Akira, T. Taniguchi, P. J. Murray, et al. 2004. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173: 7416-7425.
-
(2004)
J. Immunol.
, vol.173
, pp. 7416-7425
-
-
Stockinger, S.1
Reutterer, B.2
Schaljo, B.3
Schellack, C.4
Brunner, S.5
Materna, T.6
Yamamoto, M.7
Akira, S.8
Taniguchi, T.9
Murray, P.J.10
-
73
-
-
12444297471
-
Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TANK-binding kinase 1
-
O'Connell, R. M., S. A. Vaidya, A. K. Perry, S. K. Saha, P. W. Dempsey, and G. Cheng. 2005. Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TANK-binding kinase 1. J. Immunol. 174: 1602-1607.
-
(2005)
J. Immunol.
, vol.174
, pp. 1602-1607
-
-
O'Connell, R.M.1
Vaidya, S.A.2
Perry, A.K.3
Saha, S.K.4
Dempsey, P.W.5
Cheng, G.6
-
74
-
-
0037844850
-
Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators
-
Yang, H., C. H. Lin, G. Ma, M. O. Baffi, and M. G. Wathelet. 2003. Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators. J. Biol. Chem. 278: 15495-15504.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15495-15504
-
-
Yang, H.1
Lin, C.H.2
Ma, G.3
Baffi, M.O.4
Wathelet, M.G.5
-
75
-
-
5444274514
-
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai, T., S. Sato, K. J. Ishii, C. Coban, H. Hemmi, M. Yamamoto, K. Terai, M. Matsuda, J. Inoue, S. Uematsu, O. Takeuchi, and S. Akira. 2004. Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat. Immunol. 5: 1061-1068.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
Yamamoto, M.6
Terai, K.7
Matsuda, M.8
Inoue, J.9
Uematsu, S.10
Takeuchi, O.11
Akira, S.12
|