Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion

Infection and Immunity

Volumn 72, Issue 7, 2004, Pages 3951-3960

  Johnson, Raymond M ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CHEMOKINE; CXCL16 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; PROTEIN P70; RANTES; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL REPRODUCTION; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; HOST RESISTANCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NONHUMAN; NORTHERN BLOTTING; OVIDUCT; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCAR FORMATION;

ANIMALS; CHLAMYDIA INFECTIONS; CHLAMYDIA MURIDARUM; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; FALLOPIAN TUBES; FEMALE; HUMANS; INTERLEUKIN-12; MICE; PROTEIN SUBUNITS; RNA, MESSENGER;

EID: 3042542185     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.7.3951-3960.2004     Document Type: Article

References (76)

1. Agostini, C., L. Trentin, R. Sancetta, M. Facco, C. Tassinari, A. Cerutti, M. Bortolin, A. Milani, M. Siviero, R. Zambello, and G. Semenzato. 1997. Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome. Blood 90:1115-1123.
2. Alferink, J., I. Lieberam, W. Reindl, A. Behrens, S. Weiss, N. Huser, K. Gerauer, R. Ross, A. B. Reske-Kunz, P. Ahmad-Nejad, H. Wagner, and I. Forster. 2003. Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J. Exp. Med. 197:585-599.
3. Ault, K. A., O. W. Tawfik, M. M. Smith-King, J. Gunter, and P. F. Terranova. 1996. Tumor necrosis factor-alpha response to infection with Chlamydia trachomatis in human fallopian tube organ culture. Am. J. Obstet. Gynecol. 175:1242-1245.
4. Barlow, R. E., I. D. Cooke, O. Odukoya, M. K. Heatley, J. Jenkins, G. Narayansingh, S. S. Ramsewak, and A. Eley. 2001. The prevalence of Chlamydia trachomatis in fresh tissue specimens from patients with ectopic pregnancy or tubal factor infertility as determined by PCR and in-situ hybridisation. J. Med. Microbiol. 50:902-908.
5. Barron, A. L., H. J. White, R. G. Rank, B. L. Soloff, and E. B. Moses. 1981. A new animal model for the study of Chlamydia trachomatis genital infections: infection of mice with the agent of mouse pneumonitis. J. Infect. Dis. 143:63-66.
6. Biron, C. A. 2001. Interferons alpha and beta as immune regulators-a new look. Immunity 14:661-664.
7. Bishop, B., and C. M. Lloyd. 2003. CC chemokine ligand 1 promotes recruitment of eosinophils but not Th2 cells during the development of allergic airways disease. J. Immunol. 170:4810-4817.
8. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187: 129-134.
9. Bozza, M., J. L. Bliss, A. J. Dorner, and W. L. Trepicchio. 2001. Interleukin-11 modulates Th1/Th2 cytokine production from activated CD4+ T cells. J. Interferon Cytokine Res. 21:21-30.
10. Brooks, C. G., M. Holscher, and D. Urdal. 1985. Natural killer activity in cloned cytotoxic T lymphocytes: regulation by interleukin 2, interferon, and specific antigen. J. Immunol. 135:1145-1152.
11. Campbell, L. A., D. L. Patton, D. E. Moore, A. L. Cappuccio, B. A. Mueller, and S. P. Wang. 1993. Detection of Chlamydia trachomatis deoxyribonucleic acid in women with tubal infertility. Fertil. Steril. 59:45-50.
12. Cates, W., Jr., R. T. Rolfs, Jr., and S. O. Aral. 1990. Sexually transmitted diseases, pelvic inflammatory disease, and infertility: an epidemiologic update. Epidemiol. Rev. 12:199-220.
13. Coste, J., B. Laumon, A. Bremond, P. Collet, and N. Job-Spira. 1994. Sexually transmitted diseases as major causes of ectopic pregnancy: results from a large case-control study in France. Fertil. Steril. 62:289-295.
14. Cotter, T. W., and G. I. Byrne. 1996. Immunity to Chlamydia: comparison of human infections and murine models. Res. Immunol. 147:587-595.
15. Curtsinger, J. M., C. S. Schmidt, A. Mondino, D. C. Lins, R. M. Kedl, M. K. Jenkins, and M. F. Mescher. 1999. Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells. J. Immunol. 162: 3256-3262.
16. Darville, T., C. W. Andrews, Jr., J. D. Sikes, P. L. Fraley, and R. G. Rank. 2001. Early local cytokine profiles in strains of mice with different outcomes from chlamydial genital tract infection. Infect. Immun. 69:3556-3561.
17. Dean, D. 1997. Chlamydia infections of Chlamydia trachomatis, p. 473-497. In D. H. Connor, F. W. Chandler, D. A. Schwartz, H. J. Manz, and E. E. Lack (ed.), Pathology of infectious diseases. Appleton & Lange, Stamford, Conn.
18. Decken, K., G. Kohler, K. Palmer-Lehmann, A. Wunderlin, F. Mattner, J. Magram, M. K. Gately, and G. Alber. 1998. Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans. Infect. Immun. 66:4994-5000.
19. Dessus-Babus, S., T. L. Darville, F. P. Cuozzo, K. Ferguson, and P. B. Wyrick. 2002. Differences in innate immune responses (in vitro) to HeLa cells infected with nondisseminating serovar E and disseminating serovar L2 of Chlamydia trachomatis. Infect. Immun. 70:3234-3248.
20. Dessus-Babus, S., S. T. Knight, and P. B. Wyrick. 2000. Chlamydial infection of polarized HeLa cells induces PMN chemotaxis but the cytokine profile varies between disseminating and non-disseminating strains. Cell Microbiol. 2:317-327.
21. Flad, H. D., E. Grage-Griebenow, F. Petersen, B. Scheuerer, E. Brandt, J. Baran, J. Pryjma, and M. Ernst. 1999. The role of cytokines in monocyte apoptosis. Pathobiology 67:291-293.
22. Germann, T., and E. Rude. 1995. Interleukin-12. Int. Arch. Allergy Immunol. 108:103-112.
23. Grafi, G., I. Sela, and G. Galili. 1993. Translational regulation of human beta interferon mRNA: association of the 3′ AU-rich sequence with the poly(A) tail reduces translation efficiency in vitro. Mol. Cell. Biol. 13:3487-3493.
24. Hardie, W. D., M. D. Bruno, K. M. Huelsman, H. S. Iwamoto, P. E. Carrigan, G. D. Leikauf, J. A. Whitsett, and T. R. Korfhagen. 1997. Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha. Am. J. Pathol. 151:1075-1083.
25. Hess, S., C. Rheinheimer, F. Tidow, G. Bartling, C. Kaps, J. Lauber, J. Buer, and A. Klos. 2001. The reprogrammed host: Chlamydia trachomatis-induced up-regulation of glycoprotein 130 cytokines, transcription factors, and anti-apoptotic genes. Arthritis Rheum. 44:2392-2401.
26. Hobbs, M. V., W. O. Weigle, D. J. Noonan, B. E. Torbett, R. J. McEvilly, R. J. Koch, G. J. Cardenas, and D. N. Ernst. 1993. Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J. Immunol. 150: 3602-3614.
27. Holscher, C., R. A. Atkinson, B. Arendse, N. Brown, E. Myburgh, G. Alber, and F. Brombacher. 2001. A protective and agonistic function of IL-12p40 in mycobacterial infection. J. Immunol. 167:6957-6966.
28. Huang, J. S., Y. H. Wang, T. Y. Ling, S. S. Chuang, F. E. Johnson, and S. S. Huang. 2002. Synthetic TGF-beta antagonist accelerates wound healing and reduces scarring. FASEB J. 16:1269-1270.
29. Humbles, A. A., D. M. Conroy, S. Marleau, S. M. Rankin, R. T. Palframan, A. E. Proudfoot, T. N. Wells, D. Li, P. K. Jeffery, D. A. Griffiths-Johnson, T. J. Williams, and P. J. Jose. 1997. Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo. J. Exp. Med. 186:601-612.
30. Kagnoff, M. F., and L. Eckmann. 1997. Epithelial cells as sensors for microbial infection. J. Clin. Investig. 100:6-10.
31. Kalinski, P., P. L. Vieira, J. H. Schuitemaker, E. C. de Jong, and M. L. Kapsenberg. 2001. Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 97:3466-3469.
32. Kaushic, C., K. Grant, M. Crane, and C. R. Wira. 2000. Infection of polarized primary epithelial cells from rat uterus with Chlamydia trachomatis: cell-cell interaction and cytokine secretion. Am. J. Reprod. Immunol. 44:73-79.
33. Kim, C. H., E. J. Kunkel, J. Boisvert, B. Johnston, J. J. Campbell, M. C. Genovese, H. B. Greenberg, and E. C. Butcher. 2001. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Investig. 107:595-601.
34. Kinoshita, N., T. Hiroi, N. Ohta, S. Fukuyama, E. J. Park, and H. Kiyono. 2002. Autocrine IL-15 mediates intestinal epithelial cell death via the activation of neighboring intraepithelial NK cells. J. Immunol. 169:6187-6192.
35. Kuo, C., and W. J. Chen. 1980. A mouse model of Chlamydia trachomatis pneumonitis. J. Infect. Dis. 141:198-202.
36. Lehmann, J., S. Bellmann, C. Werner, R. Schroder, N. Schutze, and G. Alber. 2001. IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis. J. Immunol. 167:5304-5315.
37. Lin, Z. Q., T. Kondo, Y. Ishida, T. Takayasu, and N. Mukaida. 2003. Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice. J. Leukoc. Biol. 73:713-721.
38. Liu, W., and R. J. Kurlander. 1995. Analysis of the interrelationship between IL-12, TNF-alpha, and IFN-gamma production during murine listeriosis. Cell Immunol. 163:260-267.
39. Lu, H., C. Shen, and R. C. Brunham. 2000. Chlamydia trachomatis infection of epithelial cells induces the activation of caspase-1 and release of mature IL-18. J. Immunol. 165:1463-1469.
40. Madtes, D. K., A. L. Elston, R. C. Hackman, A. R. Dunn, and J. G. Clark. 1999. Transforming growth factor-alpha deficiency reduces pulmonary fibrosis in transgenic mice. Am. J. Respir. Cell. Mol. Biol. 20:924-934.
41. Mantovani, A., and E. Dejana. 1989. Cytokines as communication signals between leukocytes and endothelial cells. Immunol. Today. 10:370-375.
42. Marelli-Berg, F. M., and R. I. Lechler. 1999. Antigen presentation by parenchymal cells: a route to peripheral tolerance? Immunol. Rev. 172:297-314.
43. Matloubian, M., A. David, S. Engel, J. E. Ryan, and J. G. Cyster. 2000. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat. Immunol. 1:298-304.
44. Maxion, H. K., and K. A. Kelly. 2002. Chemokine expression patterns differ within anatomically distinct regions of the genital tract during Chlamydia trachomatis infection. Infect. Immun. 70:1538-1546.
45. McCormack, W. M., S. Alpert, D. E. McComb, R. L. Nichols, D. Z. Semine, and S. H. Zinner. 1979. Fifteen-month follow-up study of women infected with Chlamydia trachomatis. N. Engl. J. Med. 300:123-125.
46. Ming, J. E., C. Cernetti, R. M. Steinman, and A. Granelli-Piperno. 1989. Interleukin 6 is the principal cytolytic T lymphocyte differentiation factor for thymocytes in human leukocyte conditioned medium. J. Mol. Cell. Immunol. 4:203-211.
47. Moller, B. R., L. Westrom, S. Ahrons, K. T. Ripa, L. Svensson, C. von Mecklenburg, H. Henrikson, and P. A. Mardh. 1979. Chlamydia trachomatis infection of the Fallopian tubes. Histological findings in two patients. Br J. Vener. Dis. 55:422-428.
48. Morrison, R. P., and H. D. Caldwell. 2002. Immunity to murine chlamydial genital infection. Infect. Immun. 70:2741-2751.
49. Mueller, Y. M., P. M. Bojczuk, E. S. Halstead, A. H. Kim, J. Witek, J. D. Altman, and P. D. Katsikis. 2003. IL-15 enhances survival and function of HIV-specific CD8+ T cells. Blood 101:1024-1029.
50. Nguyen, K. B., W. T. Watford, R. Salomon, S. R. Hofmann, G. C. Pien, A. Morinobu, M. Gadina, J. J. O'Shea, and C. A. Biron. 2002. Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science 297:2063-2066.
51. Okada, M., M. Kitahara, S. Kishimoto, T. Matsuda, T. Hirano, and T. Kishimoto. 1988. IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J. Immunol. 141:1543-1549.
52. Olson, T. S., and K. Ley. 2002. Chemokines and chemokine receptors in leukocyte trafficking. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283:R7-R28.
53. Ossewaarde, J. M., A. de Vries, T. Bestebroer, and A. F. Angulo. 1996. Application of a Mycoplasma group-specific PCR for monitoring decontamination of Mycoplasma-infected Chlamydia sp. strains. Appl. Environ. Microbiol. 62:328-331.
54. Patton, D. L., M. Askienazy-Elbhar, J. Henry-Suchet, L. A. Campbell, A. Cappuccio, W. Tannous, S. P. Wang, and C. C. Kuo. 1994. Detection of Chlamydia trachomatis in fallopian tube tissue in women with postinfectious tubal infertility. Am. J. Obstet. Gynecol. 171:95-101.
55. Polo, M., F. Ko, F. Busillo, C. W. Cruse, T. J. Krizek, and M. C. Robson. 1997. Cytokine production in patients with hypertrophic burn scars. J. Burn Care Rehabil. 18:477-482.
56. Popescu, N. C., J. A. DiPaolo, and S. C. Amsbaugh. 1987. Integration sites of human papillomavirus 18 DNA sequences on HeLa cell chromosomes. Cytogenet. Cell Genet. 44:58-62.
57. Rahm, V. A., H. Gnarpe, and V. Odlind. 1988. Chlamydia trachomatis among sexually active teenage girls. Lack of correlation between chlamydial infection, history of the patient and clinical signs of infection. Br J. Obstet. Gynaecol. 95:916-919.
58. Rasmussen, S. J., L. Eckmann, A. J. Quayle, L. Shen, Y. X. Zhang, D. J. Anderson, J. Fierer, R. S. Stephens, and M. F. Kagnoff. 1997. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J. Clin. Investig. 99:77-87.
59. Saba, S., G. Soong, S. Greenberg, and A. Prince. 2002. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways. Am. J. Respir. Cell. Mol. Biol. 27:561-567.
60. Sallusto, F., D. Lenig, C. R. Mackay, and A. Lanzavecchia. 1998. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187:875-883.
61. Schachter, J. (ed.). 1980. Chlamydiae (Psittacosis-lymphogranuloma venereum-trachoma group), 3rd ed. American Society for Microbiology, Washington, D.C.
62. Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659-667.
63. Shaw, J. H., V. R. Grund, L. Durling, and H. D. Caldwell. 2001. Expression of genes encoding Th1 cell-activating cytokines and lymphoid homing chemokines by chlamydia-pulsed dendritic cells correlates with protective immunizing efficacy. Infect. Immun. 69:4667-4672.
64. Shepard, M. K., and R. B. Jones. 1989. Recovery of Chlamydia trachomatis from endometrial and fallopian tube biopsies in women with infertility of tubal origin. Fertil. Steril. 52:232-238.
65. Stephens, R. S. 2003. The cellular paradigm of chlamydial pathogenesis. Trends Microbiol. 11:44-51.
66. Trepicchio, W. L., M. Bozza, G. Pedneault, and A. J. Dorner. 1996. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 157:3627-3634.
67. Trinchieri, G. 1998. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv. Immunol. 70:83-243.
68. van den Brule, A. J., C. Munk, J. F. Winther, S. K. Kjaer, H. O. Jorgensen, C. J. Meijer, and S. A. Morre. 2002. Prevalence and persistence of asymptomatic Chlamydia trachomatis infections in urine specimens from Danish male military recruits. Int. J. STD AIDS (Suppl. 13) 2:19-22.
69. White, H. D., R. H. Prabhala, S. L. Humphrey, K. M. Crassi, J. M. Richardson, and C. R. Wira. 2000. A method for the dispersal and characterization of leukocytes from the human female reproductive tract. Am. J. Reprod. Immunol. 44:96-103.
70. Wilkinson, P. C., and F. Y. Liew. 1995. Chemoattraction of human blood T lymphocytes by interleukin-15. J. Exp. Med. 181:1255-1259.
71. Wyrick, P. B. 2000. Intracellular survival by Chlamydia. Cell Microbiol. 2:275-282.
72. Wyrick, P. B., S. T. Knight, T. R. Paul, R. G. Rank, and C. S. Barbier. 1999. Persistent chlamydial envelope antigens in antibiotic-exposed infected cells trigger neutrophil chemotaxis. J. Infect. Dis. 179:954-966.
73. Xia, M., R. E. Bumgarner, M. F. Lampe, and W. E. Stamm. 2003. Chlamydia trachomatis infection alters host cell transcription in diverse cellular pathways. J. Infect. Dis. 187:424-434.
74. Xue, H., R. L. McCauley, and W. Zhang. 2000. Elevated interleukin-6 expression in keloid fibroblasts. J. Surg. Res. 89:74-77.
75. Yajima, T., H. Nishimura, R. Ishimitsu, T. Watase, D. H. Busch, E. G. Pamer, H. Kuwano, and Y. Yoshikai. 2002. Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure. J. Immunol. 168:1198-1203.
76. Zingoni, A., H. Soto, J. A. Hedrick, A. Stoppacciaro, C. T. Storlazzi, F. Sinigaglia, D. D'Ambrosio, A. O'Garra, D. Robinson, M. Rocchi, A. Santoni, A. Zlotnik, and M. Napolitano. 1998. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J. Immunol. 161:547-551.