-
1
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells
-
Weiner, H. L. (2001) Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells. Immunol. Rev. 182, 207-214
-
(2001)
Immunol. Rev.
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
2
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C. H., Miyazono, K., and ten Dijke, P. (1997) TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature (London) 390, 465-471
-
(1997)
Nature (London)
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
3
-
-
0031685620
-
TGF-β signal transduction
-
Massague, J. (1998) TGF-β signal transduction. Annu. Rev. Biochem. 67, 753-791
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
5
-
-
0034604110
-
Role of transforming growth factor β in human disease
-
Blobe, G. C., Schiemann, W. P., and Lodish, H. F. (2000) Role of transforming growth factor β in human disease. N. Engl. J. Med. 342, 1350-1358
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
6
-
-
0032849117
-
Immunologic mechanisms of specific immunotherapy
-
Akdis, C. A., and Blaser, K. (1999) Immunologic mechanisms of specific immunotherapy. Allergy 54, 31-32
-
(1999)
Allergy
, vol.54
, pp. 31-32
-
-
Akdis, C.A.1
Blaser, K.2
-
7
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
Nakao, A., Afrakhte, M., Moren, A., Nakayama, T., Christian, J. L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N. E., Heldin, C. H., et al. (1997) Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature (London) 389, 631-635
-
(1997)
Nature (London)
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.E.9
Heldin, C.H.10
-
8
-
-
0033987397
-
CD4(+) T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation
-
Hansen, G., McIntire, J. J., Yeung, V. P., Berry, G., Thorbecke, G. J., Chen, L., DeKruyff, R. H., and Umetsu, D. T. (2000) CD4(+) T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J. Clin. Invest. 105, 61-70
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 61-70
-
-
Hansen, G.1
McIntire, J.J.2
Yeung, V.P.3
Berry, G.4
Thorbecke, G.J.5
Chen, L.6
DeKruyff, R.H.7
Umetsu, D.T.8
-
9
-
-
0034679703
-
Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity
-
Nakao, A., Miike, S., Hatano, M., Okumura, K., Tokuhisa, T., Ra, C., and Iwamoto, I. (2000) Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity. J. Exp. Med. 192, 151-158
-
(2000)
J. Exp. Med.
, vol.192
, pp. 151-158
-
-
Nakao, A.1
Miike, S.2
Hatano, M.3
Okumura, K.4
Tokuhisa, T.5
Ra, C.6
Iwamoto, I.7
-
10
-
-
0032525893
-
Plasmid DNA encoding transforming growth factor-β1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model
-
Song, X. Y., Gu, M., Jin, W. W., Klinman, D. M., and Wahl, S. M. (1998) Plasmid DNA encoding transforming growth factor-β1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model. J. Clin. Invest. 101, 2615-2621
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2615-2621
-
-
Song, X.Y.1
Gu, M.2
Jin, W.W.3
Klinman, D.M.4
Wahl, S.M.5
-
11
-
-
0034894059
-
Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease
-
Monteleone, G., Kumberova, A., Croft, N. M., McKenzie, C., Steer, H. W., and MacDonald, T. T. (2001) Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease. J. Clin. Invest. 108, 601-609
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 601-609
-
-
Monteleone, G.1
Kumberova, A.2
Croft, N.M.3
McKenzie, C.4
Steer, H.W.5
MacDonald, T.T.6
-
12
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor
-
Tsukazaki, T., Chiang, T. A., Davison, A. F., Attisano, L., and Wrana, J. L. (1998) SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor. Cell 95, 779-791
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, J.L.5
-
13
-
-
0034462833
-
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA
-
Miura, S., Takeshita, T., Asao, H., Kimura, Y., Murata, K., Sasaki, Y., Hanai, J. I., Beppu, H., Tsukazaki, T., Wrana, J. L., et al. (2000) Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA. Mol. Cell. Biol. 20, 9346-9355
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9346-9355
-
-
Miura, S.1
Takeshita, T.2
Asao, H.3
Kimura, Y.4
Murata, K.5
Sasaki, Y.6
Hanai, J.I.7
Beppu, H.8
Tsukazaki, T.9
Wrana, J.L.10
-
14
-
-
0033969934
-
Microtubule binding to Smads may regulate TGF-β activity
-
Dong, C., Li, Z., Alvarez, R., Jr., Feng, X. H., and Goldschmidt-Clermont, P. J. (2000) Microtubule binding to Smads may regulate TGF-β activity. Mol. Cell 5, 27-34
-
(2000)
Mol. Cell
, vol.5
, pp. 27-34
-
-
Dong, C.1
Li, Z.2
Alvarez R., Jr.3
Feng, X.H.4
Goldschmidt-Clermont, P.J.5
-
15
-
-
0034614708
-
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
-
Wu, G., Chen, Y. G., Ozdamar, B., Gyuricza, C. A., Chong, P. A., Wrana, J. L., Massague, J., and Shi, Y. (2000) Structural basis of Smad2 recognition by the Smad anchor for receptor activation. Science 287, 92-97
-
(2000)
Science
, vol.287
, pp. 92-97
-
-
Wu, G.1
Chen, Y.G.2
Ozdamar, B.3
Gyuricza, C.A.4
Chong, P.A.5
Wrana, J.L.6
Massague, J.7
Shi, Y.8
-
16
-
-
0032581296
-
Vesicular transport. Sticky fingers grab a lipid
-
Wiedemann, C., and Cockcroft, S. (1998) Vesicular transport. Sticky fingers grab a lipid. Nature (London) 394, 426-427
-
(1998)
Nature (London)
, vol.394
, pp. 426-427
-
-
Wiedemann, C.1
Cockcroft, S.2
-
17
-
-
0036201871
-
The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling
-
Itoh, F., Divecha, N., Brocks, L., Oomen, L., Janssen, H., Calafat, J., Itoh, S., and Dijke Pt, P. (2002) The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling. Genes Cells 7, 321-331
-
(2002)
Genes Cells
, vol.7
, pp. 321-331
-
-
Itoh, F.1
Divecha, N.2
Brocks, L.3
Oomen, L.4
Janssen, H.5
Calafat, J.6
Itoh, S.7
Dijke, P.T.8
-
18
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation
-
Xu, L., Chen, Y. G., and Massague, J. (2000) The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation. Nat. Cell. Biol. 2, 559-562
-
(2000)
Nat. Cell. Biol.
, vol.2
, pp. 559-562
-
-
Xu, L.1
Chen, Y.G.2
Massague, J.3
-
19
-
-
0028849793
-
Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain
-
Komada, M., and Kitamura, N. (1995) Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol. Cell. Biol. 15, 6213-6221
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6213-6221
-
-
Komada, M.1
Kitamura, N.2
-
20
-
-
14444284098
-
Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth
-
Asao, H., Sasaki, Y., Arita, T., Tanaka, N., Endo, K., Kasai, H., Takeshita, T., Endo, Y., Fujita, T., and Sugamura, K. (1997) Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth. J. Biol. Chem. 272, 32785-32791
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32785-32791
-
-
Asao, H.1
Sasaki, Y.2
Arita, T.3
Tanaka, N.4
Endo, K.5
Kasai, H.6
Takeshita, T.7
Endo, Y.8
Fujita, T.9
Sugamura, K.10
-
21
-
-
0030846562
-
Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes
-
Komada, M., Masaki, R., Yamamoto, A., and Kitamura, N. (1997) Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J. Biol. Chem. 272, 20538-20544
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20538-20544
-
-
Komada, M.1
Masaki, R.2
Yamamoto, A.3
Kitamura, N.4
-
22
-
-
0032516862
-
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer
-
Jonk, L. J., Itoh, S., Heldin, C. H., ten Dijke, P., and Kruijer, W. (1998) Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer. J. Biol. Chem. 273, 21145-21152
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21145-21152
-
-
Jonk, L.J.1
Itoh, S.2
Heldin, C.H.3
Ten Dijke, P.4
Kruijer, W.5
-
23
-
-
0034531692
-
Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells
-
Akdis, M., Klunker, S., Schliz, M., Blaser, K., and Akdis, C. A. (2000) Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells. Eur. J. Immunol. 30, 3533-3541
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 3533-3541
-
-
Akdis, M.1
Klunker, S.2
Schliz, M.3
Blaser, K.4
Akdis, C.A.5
-
24
-
-
0034039840
-
IL-10 directly acts on T cells by specifically altering the CD28 costimulation pathway
-
Joss, A., Akdis, M., Faith, A., Blaser, K., and Akdis, C. A. (2000) IL-10 directly acts on T cells by specifically altering the CD28 costimulation pathway. Eur. J. Immunol. 30, 1683-1690
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1683-1690
-
-
Joss, A.1
Akdis, M.2
Faith, A.3
Blaser, K.4
Akdis, C.A.5
-
25
-
-
0035806290
-
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
-
Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J., and Enk, A. H. (2001) Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193, 1285-1294
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1285-1294
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
26
-
-
0035879091
-
Regulation of TGF-β response during T cell activation is modulated by IL-10
-
Cottrez, F., and Groux, H. (2001) Regulation of TGF-β response during T cell activation is modulated by IL-10. J. Immunol. 167, 773-778
-
(2001)
J. Immunol.
, vol.167
, pp. 773-778
-
-
Cottrez, F.1
Groux, H.2
-
28
-
-
0033602101
-
Inhibition of transforming growth factor-β/SMAD signalling by the interferon-gamma/STAT pathway
-
Ulloa, L., Doody, J., and Massague, J. (1999) Inhibition of transforming growth factor-β/SMAD signalling by the interferon-gamma/STAT pathway. Nature (London) 397, 710-713
-
(1999)
Nature (London)
, vol.397
, pp. 710-713
-
-
Ulloa, L.1
Doody, J.2
Massague, J.3
-
29
-
-
0022465625
-
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth
-
Kehrl, J. H., Wakefield, L. M., Roberts, A. B., Jakowlew, S., Alvarez-Mon, M., Derynck, R., Sporn, M. B., and Fauci, A. S. (1986) Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 163, 1037-1050
-
(1986)
J. Exp. Med.
, vol.163
, pp. 1037-1050
-
-
Kehrl, J.H.1
Wakefield, L.M.2
Roberts, A.B.3
Jakowlew, S.4
Alvarez-Mon, M.5
Derynck, R.6
Sporn, M.B.7
Fauci, A.S.8
-
30
-
-
0030753766
-
Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid
-
Redington, A. E., Madden, J., Frew, A. J., Djukanovic, R., Roche, W. R., Holgate, S. T., and Howarth, P. H. (1997) Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid. Am. J. Respir. Crit. Care Med. 156, 642-647
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.156
, pp. 642-647
-
-
Redington, A.E.1
Madden, J.2
Frew, A.J.3
Djukanovic, R.4
Roche, W.R.5
Holgate, S.T.6
Howarth, P.H.7
-
31
-
-
8544230635
-
Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis
-
Vignola, A. M., Chanez, P., Chiappara, G., Merendino, A., Pace, E., Rizzo, A., la Rocca, A. M., Bellia, V., Bonsignore, G., and Bousquet, J. (1997) Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am. J. Respir. Crit. Care Med. 156, 591-599
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.156
, pp. 591-599
-
-
Vignola, A.M.1
Chanez, P.2
Chiappara, G.3
Merendino, A.4
Pace, E.5
Rizzo, A.6
La Rocca, A.M.7
Bellia, V.8
Bonsignore, G.9
Bousquet, J.10
-
32
-
-
0034810922
-
Interaction between Smad anchor for receptor activation and Smad3 is not essential for TGF-β/Smad3-mediated signaling
-
Goto, D., Nakajima, H., Mori, Y., Kurasawa, K., Kitamura, N., and Iwamoto, I. (2001) Interaction between Smad anchor for receptor activation and Smad3 is not essential for TGF-β/Smad3-mediated signaling. Biochem. Biophys. Res. Commun. 281, 1100-1105
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 1100-1105
-
-
Goto, D.1
Nakajima, H.2
Mori, Y.3
Kurasawa, K.4
Kitamura, N.5
Iwamoto, I.6
-
33
-
-
0034677631
-
PIP2 and PIP3: Complex roles at the cell surface
-
Czech, M. P. (2000) PIP2 and PIP3: complex roles at the cell surface. Cell 100, 60-606
-
(2000)
Cell
, vol.100
, pp. 60-606
-
-
Czech, M.P.1
-
34
-
-
0037080983
-
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif
-
Randall, R. A., Germain, S., Inman, G. J., Bates, P. A., and Hill, C. S. (2002) Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J. 21, 145-156
-
(2002)
EMBO J.
, vol.21
, pp. 145-156
-
-
Randall, R.A.1
Germain, S.2
Inman, G.J.3
Bates, P.A.4
Hill, C.S.5
|