Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis

Oncogene

Volumn 24, Issue 24, 2005, Pages 3954-3963

  Zhang, Rong ^a   Luo, Dianhong ^a   Miao, Robert ^b   Bai, Lanfang ^a   Ge, Qingyuan ^c   Sessa, William C ^b   Min, Wang ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CELL SIGNALING TECHNOLOGY   (United States)

Author keywords

17 allyamino 17 demethoxygeldanamycin (17 AAG); Akt; Apoptosis; ASK1; Hsp90; Hydrogen peroxide

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; 2 MORPHOLINO 8 PHENYLCHROMONE; 4',6 DIAMIDINO 2 PHENYLINDOLE; ADENOVIRUS VECTOR; APOPTOSIS SIGNAL REGULATING KINASE 1; HEAT SHOCK PROTEIN 90; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SYNAPTOPHYSIN; AKT1 PROTEIN, HUMAN; MAP3K5 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CATTLE; CELL CULTURE; CYTOLOGY; GENETIC TRANSFECTION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENES, REPORTER; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MAP KINASE KINASE KINASE 5; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSFECTION; UMBILICAL VEINS;

EID: 20544446881     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208548     Document Type: Article

References (42)

1. Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P and Rosen N. (2002). J. Biol. Chem., 277, 39858-39866.
2. Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S and Reed JC. (1998). Science, 282, 1318-1321.
3. Chang HY, Nishitoh H, Yang X, Ichijo H and Baltimore D. (1998). Science, 281, 1860-1863.
4. Charette SJ, Lambert H and Landry J. (2001). J. Biol. Chem., 276, 36071-36074.
5. Chen J. Fujii K, Zhang L, Roberts T and Fu H. (2001). Proc. Natl. Acad. Sci. USA, 98, 7783-7788.
6. Cross DA, Alessi DR, Cohen P, Andjelkovich M and Hemmings BA. (1995). Nature, 378, 785-789.
7. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y and Greenberg ME. (1997). Cell, 91, 231-241.
8. Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR and Greenberg ME. (1997). Science, 275, 661-665.
9. Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T and Sessa WC. (2002). Circ. Res., 90, 866-873.
10. Franke TF, Kaplan DR and Cantley LC. (1997). Cell, 88, 435-437.
11. Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A and Sessa WC. (1999). Nature, 399, 597-601.
12. Garcia-Cardena G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A and Sessa WC. (1998). Nature, 392, 821-823.
13. Grenert JP, Sullivan WP, Fadden P, Haystead TAJ, Clark J, Mimnaugh E, Krutzsch H, Ochel HJ, Schulte TW, Sausville E, Neckers LM and Toft DO. (1997). J. Biol. Chem., 272, 23843-23850.
14. Hatai T, Matsuzawa A, Inoshita S, Mochida Y, Kuroda T, Sakamaki K, Kuida K, Yonehara S, Ichijo H and Takeda K. (2000). J. Biol. Chem., 275, 26576-26581.
15. Ichijo H, Nishida E, Irie K, ten D-P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K and Gotoh Y. (1997). Science, 275, 90-94.
16. Kim AH, Khursigara G, Sun X, Franke TF and Chao MV. (2001). Mol. Cell. Biol., 21, 893-901.
17. Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL and Burgering BM. (1999). Nature, 398, 630-634.
18. Lewis J, Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L and Liu ZG. (2000). J. Biol. Chem., 275, 10519-10526.
19. Liu H, Nishitoh H, Ichijo H and Kyriakis JM. (2000). Mol. Cell. Biol., 20, 2198-2208.
20. Liu Y, Yin G, Surapisitchat J, Berk BC and Min W. (2001). J. Clin. Invest, 107, 917-923.
21. Matsuura H, Nishitoh H, Takeda K, Matsuzawa A, Amagasa T, Ito M, Yoshioka K and Ichijo H. (2002). J. Biol. Chem., 277, 40703-40709.
22. Min W and Pober JS. (1997). J. Immunol., 159, 3508-3518.
23. Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H and Ichijo H. (2001). EMBO J., 20, 6028-6036.
24. Neckers L. (2002). Trends Mol. Med., 8, S55-S61.
25. Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A and Ichijo H. (2002). Genes Dev., 16, 1345-1355.
26. Park HS, Cho SG, Kim CK, Hwang HS, Noh KT, Kim MS, Huh SH, Kim MJ, Ryoo K, Kim EK, Kang WJ, Lee JS, Seo JS, Ko YG, Kim S and Choi EJ. (2002). Mol. Cell. Biol., 22, 7721-7730.
27. Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW and Pearl LH. (1997). Cell, 90, 65-75.
28. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K and Ichijo H. (1998). EMBO J., 17, 2596-2606.
29. Sato S, Fujita N and Tsuruo T. (2000). Proc. Natl. Acad. Sci. USA, 97, 10832-10837.
30. Schneider C, Sepp-Lorenzino L, Nimmesgern E, Ouerfelli O, Danishefsky S, Rosen N and Hartl FU. (1996). Proc. Natl. Acad. Sci. USA, 93, 14536-14541.
31. Schulte TW, An WG and Neckers LM. (1997). Biochem. Biophys. Res. Commun., 239, 655-659.
32. Song JJ, Rhee JG, Suntharalingam M, Walsh SA, Spitz DR and Lee YJ. (2002). J. Biol. Chem., 277, 46566-46575.
33. Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T and Ichijo H. (2001). EMBO Rep, 2, 222-228.
34. Tobiume K, Saitoh M and Ichijo H. (2002). J. Cell. Physiol., 191, 95-104.
35. Vanden Berghe T, Kalai M, van Loo G, Declercq W and Vandenabeele P. (2003). J. Biol. Chem., 278, 5622-5629.
36. Vanhaesebroeck B and Alessi DR. (2000). Biochem. J., 346 (Part 3), 561-576.
37. Whitesell L, Mimnaugh EG, De-Costa B, Myers CE and Neckers LM. (1994). Proc. Natl. Acad. Sci. USA, 91, 8324-8328.
38. Zhang H, Wu W, Du Y, Santos SJ, Conrad SE, Watson JT, Grammatikakis N and Gallo KA. (2004a). J. Biol. Chem., 279, 19457-19463.
39. Zhang H, Zhang R, Luo Y, D'Alessio A, Pober JS and Min W. (2004b). J. Biol. Chem., 279, 44955-4965.
40. Zhang L, Chen J and Fu H. (1999). Proc. Natl. Acad. Sci. USA, 96, 8511-8515.
41. Zhang R, Al-Lamki R, Bai L, Streb JW, Miano JM, Bradley J and Min W. (2004). Circ. Res., 94, 1483-1491.
42. Zhang R, He X, Liu W, Lu M, Hsieh JT and Min W. (2003). J. Clin. Invest., 111, 1933-1943.