Discovery of novel regulatory peptides by reverse pharmacology: Spotlight on chemerin and the RF-amide peptides metastin and QRFP

Current Protein and Peptide Science

Volumn 6, Issue 3, 2005, Pages 265-278

  Kutzleb, Christian ^a   Busmann, Annette ^a   Wendland, Martin ^a   Maronde, Erik ^a  

^a IPF PHARMACEUTICALS GMBH   (Germany)

Author keywords

Chemerin; GPCR; Metastin; Orphan receptor; QRFP; Reverse pharmacology; RF amide; TIG2

Indexed keywords

ANTIMETASTATIC AGENT; CHEMERIN; CHEMOATTRACTANT; G PROTEIN COUPLED RECEPTOR; METASTIN; PYROGLUTAMYLATED ARGININE PHENYLALANINE AMIDE PEPTIDE; REGULATOR PROTEIN; TAZAROTENE; UNCLASSIFIED DRUG;

ALDOSTERONE RELEASE; BONE DEVELOPMENT; CANCER INVASION; DENDRITIC CELL; DOWNSTREAM PROCESSING; DRUG TARGETING; ENDOCRINE FUNCTION; FOOD INTAKE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GONAD DEVELOPMENT; HORMONAL REGULATION; HUMAN; IMMUNE RESPONSE; INFLAMMATION; METASTASIS INHIBITION; NONHUMAN; OVARY CARCINOMA; PREGNANCY; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN STRUCTURE; PSORIASIS; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINES; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; LIGANDS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEOPLASMS; OLIGOPEPTIDES; PHARMACOLOGY; PREGNANCY; PROTEINS; RATS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TROPHOBLASTS; TUMOR SUPPRESSOR PROTEINS;

EID: 20444443901     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389203054065419     Document Type: Review

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