Identification and functional characterization of hemorphins VV-H-7 and LVV-H-7 as low-affinity agonists for the orphan bombesin receptor subtype 3

British Journal of Pharmacology

Volumn 138, Issue 8, 2003, Pages 1431-1440

  Lammerich, Hans Peter ^a   Busmann, Annette ^a   Kutzleb, Christian ^a   Wendland, Martin ^a   Seiler, Petra ^a   Berger, Claudia ^b   Eickelmann, Peter ^b   Meyer, Markus ^a   Forssmann, Wolf Georg ^a   Maronde, Erik ^a  

^a IPF PHARMACEUTICALS GMBH   (Germany)

^b Kali Chemie Pharma GmbH   (Germany)

Author keywords

GPCR; hBRS 3; Hemorphin; Orphan receptor; Signal transduction

Indexed keywords

BOMBESIN RECEPTOR; BOMBESIN RECEPTOR 3; FOCAL ADHESION KINASE; G PROTEIN COUPLED RECEPTOR; GASTRIN RELEASING PEPTIDE; INOSITOL TRISPHOSPHATE; LEUCYLVALYLVALYLHEMORPHIN 7; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUROMEDIN B; PEPTIDE DERIVATIVE; PHOSPHOLIPASE C; UNCLASSIFIED DRUG; VALYLVALYLHEMORPHIN 7;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CHO CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMOGLOBINS; HUMANS; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECEPTORS, BOMBESIN;

EID: 12444335267     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705177     Document Type: Article

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