Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control im mammalian cells and adjustable transcription control in mice

Journal of Gene Medicine

Volumn 7, Issue 4, 2005, Pages 518-525

  Weber, Wilfried ^a   Malphettes, Laetitia ^a   de Jesus, Maria ^b   Schoenmakers, Ronald ^a   El Baba, Marie Daoud ^c   Spielmann, Manuela ^a   Keller, Bettina ^a   Weber, Cornelia C ^a   van de Wetering, Petra ^a   Aubel, Dominique ^c   Wurm, Florian M ^b   Fussenegger, Martin ^a  

^a ETH ZURICH   (Switzerland)

^b EPFL   (Switzerland)

^c Institut Universitaire de Technologie   (France)

Author keywords

Gene regulation; Gene switch; Gene therapy; Q ON; QuoRex; RNAi; SCB1; ScbR; siRNA; Streptomyces coelicolor

Indexed keywords

BUTYROLACTONE; GLYCOPROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE THERAPY; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OPERATOR GENE; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROMOTER REGION; RNA TRANSLATION; SILENCER ELEMENT; STREPTOMYCES COELICOLOR; TISSUE ENGINEERING; TRANSCRIPTION REGULATION; TRANSGENE; TRANSLATION REGULATION;

4-BUTYROLACTONE; ANIMALS; BASE SEQUENCE; CELL LINE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PROTEIN BIOSYNTHESIS; RNA, SMALL INTERFERING; STREPTOMYCES; TRANSCRIPTION, GENETIC; TRANSGENES;

BACTERIA (MICROORGANISMS); MAMMALIA; STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 20244384715     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.682     Document Type: Article

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