Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells using polymerase II-dependent promoter derivatives

Biotechnology and Bioengineering

Volumn 88, Issue 4, 2004, Pages 417-425

  Malphettes, Laetitia ^a   Fussenegger, Martin ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

E.REX system; Enhanced green fluorescent protein; GFP; Heterologous gene regulation; Macrolide responsive gene expression; RNA interference; RNAi; siRNA; TET system; Tetracycline responsive gene expression

Indexed keywords

ANTIBIOTICS; DERIVATIVES; DRUG DOSAGE; GENES; PROTEINS;

GENE FUNCTION ANALYSIS; PROMOTERS; SHORT INTERFERING RNA (SIRNA);

RNA;

GREEN FLUORESCENT PROTEIN; MACROLIDE; RNA POLYMERASE II; SMALL INTERFERING RNA; TETRACYCLINE;

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENE FUNCTION; GENE SILENCING; GENE TARGETING; GENETIC REGULATION; MAMMAL CELL; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; PROMOTER REGION; RNA DEGRADATION; RNA INTERFERENCE; RNA TRANSLATION; TATA BOX; TISSUE ENGINEERING; TRANSACTIVATION;

ANIMALS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROSARCOMA; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; MACROLIDES; RNA, SMALL INTERFERING; TETRACYCLINE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 8844239146     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20230     Document Type: Article

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