The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats

European Journal of Neuroscience

Volumn 16, Issue 5, 2002, Pages 807-816

  Kole, Maarten H P ^a,c   Swan, Laura ^b   Fuchs, Eberhard ^a  

^a GERMAN PRIMATE CENTER   (Germany)

^b EUROPEAN NEUROSCIENCE INSTITUTE   (Germany)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

AMPA; EPSC; Hippocampus; NMDA; Phosphorylation; Tianeptine

Indexed keywords

AMPA RECEPTOR; ANTIDEPRESSANT AGENT; GLUTAMATE RECEPTOR; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHOTRANSFERASE INHIBITOR; STAUROSPORINE; TIANEPTINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; IN VITRO STUDY; MALE; MENTAL STRESS; NEUROMODULATION; NONHUMAN; PATCH CLAMP; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TIME;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CORTICOSTERONE; ELECTROPHYSIOLOGY; HIPPOCAMPUS; MALE; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RESTRAINT, PHYSICAL; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; SYNAPTIC TRANSMISSION; THIAZEPINES;

EID: 18744401321     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.02136.x     Document Type: Article

References (55)

1. Audinat, E., Rossier, J., Spedding, M. & Muñoz, C. (2001) Tianeptine modifies hippocampal function directly in vitro. Soc. Neurosci. Abstr., 27, 259.25.
2. Bartanusz, V., Aubry, J.-M., Pagliusi, S., Jezova, D., Baffi, J. & Kiss, J.Z. (1995) Stress-induced changes in messenger RNA levels of N-methyl-D-aspartate and AMPA receptor subunits in selected regions of the rat hippocampus and hypothalamus. Neuroscience, 66, 247-252.
3. Berman, R.M., Cappielo, A., Anand, A., Oren, D.A., Heninger, G.R., Charney, D.S. & Krystal, J.H. (2000) Antidepressant effects of ketamine in depressed patients. Biol. Psychiatry, 47, 351-354.
4. Bouron, A. & Chatton, J.-Y. (1999) Acute application of the tricyclic antidepressant desipramine presynaptically stimulates the exocytosis of glutamate in the hippocampus. Neuroscience, 90, 729-736.
5. Boyer, P.-A., Skolnick, P. & Fossom, L.H. (1998) Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridiation study. J. Mol. Neurosci., 10, 219-233.
6. Broqua, P., Baudrie, V., Laud, D. & Chauloff, F. (1992) Influence of the novel antidepressant tianeptine on neurochemical, neuroendocrinological, and behavioral effects of stress in rats. Biol. Psych., 31, 391-400.
7. Budziszewska, B., Jaworska-Feil, L., Kajta, M. & Lasoñ, W. (2000) Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - A possible mechanism. Br. J. Pharmacol., 130, 1385-1393.
8. 2+ blockade of synaptically activated N-methyl-D-aspartate receptor-channels in CA1 pyramidal neurons in kainic acid-lesioned rat hippocampus. Neuroscience, 88, 727-739.
9. Colino, A., Garcia-Seoane, J.J. & Valetin, A. (1998) Action potential broadening induced by lithium may cause a presynaptic enhancement of excitatory synaptic transmission in neonatal rat hippocampus. Eur. J. Neurosci., 10, 2433-2443.
10. Coppen, A.J. & Doogan, D.P. (1988) Serotonin and its place in the pathogenesis of depression. J. Clin. Psychiatry, 49 (Suppl.), 4-11.
11. Couet, W., Girault, J., Latrille, F., Salvadori, C. & Fourtillan, J.B. (1990) Kinetic profiles of tianeptine and its MC5 metabolite in plasma, blood and brain after single and chronic intraperitoneal administration in the rat. Eur. J. Drug Metab. Pharmacokinet., 15, 69-74.
12. Czéh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomuci, A. & Fuchs, E. (2001) Stress-induced change in cerebral metabolites. Hippoccampal volume and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc. Natl. Acad. Sci. USA, 98, 12796-12801.
13. Debanne, D., Gähwiler, B.H. & Thompson, S.M. (1998) Long-term synaptic plasticity between pairs of individual CA3 pyramidal cells in rat hippocampal slice cultures. J. Physiol. (Lond.), 507, 237-247.
14. Delbende, C., Bunel, D.T., Tarozzo, G., Grino, M., Oliver, C., Mocaër, E. & Vaudry, H. (1994) Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis. Eur. J. Pharmacol., 251, 245-251.
15. Dresse, A. & Scuvée-Moreau, J. (1988) Electrophysiological effects of tianeptine on rat locus ceruleus, raphe dorsalis, and hippocampus activity. Clin. Neuropharmacol., 11 (Suppl. 2), S51-S58.
16. Hayashi, T., Umemori, H., Mishina, M. & Yasamoto, T. (1999) The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn. Nature, 397, 72-76.
17. Hestrin, S., Nicoll, R.A., Perkel, D.J. & Sah, P. (1990) Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices. J. Physiol. (Lond.), 422, 203-225.
18. Ishizuka, N., Cowan, W.M. & Amaral, D.G. (1995) A quantitative analysis of the dendritic organization of pyramidal cells in the rat hippocampus. J. Comp. Neurol., 362, 17-45.
19. Ito, I., Futai, K., Katagiri, H., Watanabe, M., Sakimura, K., Mishina, M. & Sugyiyama, H. (1997) Synapse-selective impairment of NMDA receptor function in mice lacking NMDA receptor ε1 or ε2 subunit. J. Physiol. (Lond.), 500, 401-408.
20. Ito, I., Kawakami, R., Sakimura, K., Mishina, M. & Sugiyama, H. (2000) Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses. Neuropharmacol., 39, 943-951.
21. Kamiya, H., Shinozaki, H. & Yamamoto, C. (1996) Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses. J. Physiol. (Lond.), 493, 447-455.
22. Kim, J.J., Foy, M.R. & Thompson, R.F. (1996) Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation. Proc. Natl. Acad. Sci. USA, 93, 4750-4753.
23. Krugers, H.J., Koolhaas, J.M., Bohus, B. & Korf, J. (1993) A single social stress-experience alters glutamate receptor-binding in rat hippocampal CA3 area. Neurosci. Lett., 154, 73-77.
24. Krystal, J.H., Sanacora, G., Blumberg, H., Anand, A., Charney, D.S., Marek, G., Epperson, C.N., Goddard, A. & Mason, G.F. (2002) Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Mol. Psychiatry, 7, S71-S80.
25. Magariños, A.M., Deslandes, A. & McEwen, B.S. (1999) Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. Eur. J. Pharmacol., 371, 113-122.
26. Labrid, C., Moleyre, J., Poignant, J.C., Malen, C., Mocaer, E. & Kamoun, A. (1988) Structure-activity relationships of tricyclic antidepressants, with special reference to tianeptine. Clin. Neuropharmacol., 11(Suppl 2), S21-S31.
27. Magariños, A.M. & McEwen, B.S. (1995) Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino-acid receptors. Neuroscience, 69, 89-98.
28. Malenka, R.C. & Nicoll, R.A. (1999) Long-term potentiation - A decade of progress? Science, 285, 1870-1874.
29. Manji, H.K., Drevets, W.C. & Charney, D.S. (2001) The cellular neurobiology of depression. Nature Med., 7, 541-547.
30. McEwen, B.S. (2000) The neurobiology of stress: From serendipity to clinical relevance. Brain Res., 886, 172-189.
31. Pavlides, C., Nivón, L.G. & McEwen, B.S. (2002) Effects of chronic stress on hippocampal long-term potentiation. Hippocampus, 12, 245-257.
32. Petrie, R.X.A., Reid, I.C. & Stewart, C.A. (2000) The N-methyl-D-aspartate receptor, synaptic plasticity, and depressive disorder. A critical review. Pharmacol. Therapeut., 87, 11-25.
33. Piñeyro, G., Deveault, L., Blier, P., Dennis, T. & de Montigny, C. (1995) Effect of acute and prolonged tianeptine administration on the 5-HT transport: Electrophysiological, biochemical and radioligand binding studies in the rat brain. Naunyn-Schmiedberg's Arch. Pharmacol., 351, 111-118.
34. Popoli, M., Mori, S., Brunello, N., Perez, J., Gennarelli, M. & Racagni, G. (2001) Serine/threonine kinases as molecular targets of antidepressants: Implications for pharmacological treatment and pathophysiology of affective disorders. Pharmacol. Therapeut., 9, 149-170.
35. Salin, P.A., Scanziani, M., Malenka, R.C. & Nicoll, R.A. (1996) Distinct short-term plasticity at two excitatory synapses in the hippocampus. Proc. Natl. Acad. Sci. USA, 93, 13304-13309.
36. Sernagor, E., Kuhn, D., Vyklicky, L. Jr & Mayer, M.L. (1989) Open channel block of NMDA receptor responses evoked by tricyclic antidepressants. Neuron, 2, 1221-1227.
37. Shakesby, A.C., Anwyl, R. & Rowan, M.J. (2002) Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: Rapid actions of serotonergic and antidepressant agents. J. Neurosci., 22, 3638-3644.
38. Sheline, Y.I., Wang, P.W., Gado, M.H., Csernansky, J.G. & Vanner, M.W. (1996) Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. USA, 93, 3908-3913.
39. Skolnick, P. (1999) Antidepressants for the new millenium. Eur. J. Pharmacol., 375, 31-40.
40. Spruston, N., Jaffe, D.B., Williams, H. & Johnston, D. (1993) Voltage-and space-clamp errors associated with the measurement of electrotonically remote synaptic events. J. Neurophysiol., 70, 781-802.
41. Stewart, C.A. & Reid, I.C. (2000) Repeated ECS and fluoxetine administration have equivalent effects on hippocampal plasticity. Psychopharmacology, 148, 217-223.
42. ++ dependent protein kinase. Biochem. Biophys. Res. Comm., 135, 397-402.
43. Thomas, M.J., Beurrier, C., Bonci, A. & Malenka, R.C. (2001) Long-term depression in the nucleus accumbens: A neural correlate of behavioral sensitization to cocaine. Nature Neurosci., 4, 2117-1223.
44. Thome, J., Sakai, N., Shin, K.-H., Steffen, C., Zhang, Y.-J., Impey, S., Strom, D. & Duman, R.S. (2000) cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. J. Neurosci., 20, 4030-4036.
45. Tovar, K.R., Sprouffske, K. & Westbrook, G.L. (2000) Fast NMDA receptor-mediated synaptic currents in neurons from mice lacking the ε2 (NR2B) subunit. J. Neurophysiol., 83, 616-620.
46. Vicini, S., Wang, J.F., Li, J.H., Zhu, W.J., Wang, Y.H., Luo, J.H., Wolfe, B.B. & Grayson, D.R. (1998) Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. J. Neurophysiol., 79, 555-566.
47. Wagstaff, A.J., Ormrod, D. & Spencer, C.M. (2001) Tianeptine. A review of its use in depressive disorders. CNS Drugs, 15, 231-259.
48. Watanabe, Y., Saito, H. & Abe, K. (1993) Tricyclic antidepresssants block NMDA receptor-mediated synaptic responses and induction of long-term potentiation in rat hippocampal slices. Neuropharmacology, 32, 479-486.
49. Weiland, N.G., Orchinik, M. & Tanapat, P. (1997) Chronic corticosterone treatment induces parallel changes in N-methyl-D-aspartate receptor subunit messenger RNA levels and antagonist binding sites in the hippocampus. Neuroscience, 78, 653-662.
50. Weisskopf, M.G. & Nicoll, R.A. (1995) Presynaptic changes during mossy fibre LTP revealed by NMDA receptor-mediated synaptic responses. Nature, 376, 256-259.
51. Winder, D.G. & Sweatt, J.D. (2001) Roles of serine/threonine phosphatases in hippocampal synaptic plasticity. Nature Rev. Neurosci., 2, 461-474.
52. Wong, M.-L. & Licinio, J. (2001) Research and treatment approaches to depression. Nature Neurosci. Rev., 2, 343-351.
53. Wu, G.-Y. & Cline, H.T. (1998) Stabilization of dendritic arbor structure in vivo by CaMKII. Science, 279, 222-226.
54. 2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors. Proc. Natl. Acad. Sci. USA, 92, 1376-1380.
55. Zucker, R.S. (1999) Calcium- and activity-dependent synaptic plasticity. Curr. Opinion Neurobiol., 9, 305-313.