Maternal deprivation affects behaviour from youth to senescence: Amplification of individual differences in spatial learning and memory in senescent Brown Norway rats

European Journal of Neuroscience

Volumn 12, Issue 10, 2000, Pages 3771-3780

  Oitzl, M S ^a   Workel, J O ^a   Fluttert, M ^a   Frosch, F ^a   De Kloet, E R ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Delayed acquisition; Early life events; Impaired learning; Persistence of behaviour

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; COGNITION; CONTROLLED STUDY; JUVENILE; LEARNING; MALE; MATERNAL DEPRIVATION; MAZE TEST; MEMORY; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; RAT; RAT STRAIN; SENESCENCE; STRESS; TASK PERFORMANCE;

AGING; ANIMAL; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; FEMALE; INDIVIDUALITY; LEARNING DISORDERS; MALE; MATERNAL DEPRIVATION; MAZE LEARNING; MEMORY; MEMORY DISORDERS; RATS; STRESS, PSYCHOLOGICAL; SUPPORT, NON-U.S. GOV'T;

EID: 0033783716     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00231.x     Document Type: Article

References (50)

1. On the futility of aggregating individual learning curves
2. Early and later adoptions have different long-term effects on male rat offspring
3. Subordinateion stress: Behavioral, brain, and neuroendocrine correlates
4. Visible burrow system as a model of chronic social stress: Behavioral and neuroendocrine correlates
5. Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats
6. Aging and retrieval of words in semantic memory
7. Divergence of biological and chronological aging: Evidence from rodent studies
8. Stress and cognition: Are corticosteroids good or bad guys?
9. Hippocampal representation in spatial learning
10. Genetics of aging
11. Maternal care and the development of stress responses
12. Nongenomic transmission across generations of maternal behavior and stress responses in the rat
13. Age-related spatial reference and working memory deficits assessed in the water maze
14. Age related impairments in spatial memory are independent of those in sensorimotor skills
15. Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze
16. The use of animal models to study the effects of aging on cognition
17. Changes in learning and memory during aging
18. A model of the limbic system and basal ganglia: Applications to anxiety and schizophrenia
19. Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences
20. Behavioral mechanisms for active maternal potentiation of isolation calling in pups
21. Current experience using the laboratory rat in aging studies
22. Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats
23. Infantile experiences, strain differences, and avoidance learning
24. The ontogeny of the hypothalamic-pituitary-adrenal axis. The influence of maternal factors
25. Reliability, distribution, and validity of age-related cognitive deficits in the Morris water maze
26. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
27. Cortisol levels during human aging predict hippocampal atrophy and memory deficits
28. Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress
29. Individual differences in aging: Behavioral and neurobiological correlates
30. Stress and the aging hippocampus
31. Effects of neonatal handling on age-related impairments associated with the hippocampus
32. Environmental influences on the central nervous system and their implications for the aging rat
33. The neuropsychology of spatial cognition in the rat
34. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
35. Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine
36. The neuroendocrinology of stress and aging: The glucocorticoid cascade hypothesis
37. Glucocorticoid hypersecretion and the age-impaired hippocampus: Cause or effect?
38. Maternal deprivation and stress induce immediate early genes in the infant rat brain
39. Median eminence corticotrophin-releasing hormone content following prenatal stress and neonatal handling
40. Aging and sociosexual behavior in the male rat
41. Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors
42. Thigmotaxis as a test for anxiolytic activity in rats
43. Long-term effects of prenatal stress and postnatal handling on age-related glucocorticoid secretion and cognitive performance: A longitudinal study in the rat
44. Adrenocortical hyporesponsiveness and glucocorticoid feedback resistance in old male brown Norway rats
45. The effect of aging on stress responsiveness and central corticosteroid receptors in the brown Norway rat
46. Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone
47. Does prenatal stress impair coping and regulation of hypothalamic-pituitary-adrenal axis?
48. Perseveration on place reversals in spatial swimming pool tasks: Further evidence for place learning in hippocampal rats
49. The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24-h maternal deprivation at day 3
50. Rapid forgetting of aged rats