메뉴 건너뛰기




Volumn 33, Issue 7-8, 1998, Pages 675-687

Does growth hormone prevent or accelerate aging?

Author keywords

Body temperature; Dwarf mice; Growth hormone; Oxidative damage; Transgenic mice; Tumors

Indexed keywords

GROWTH HORMONE;

EID: 0032447232     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(98)00032-1     Document Type: Conference Paper
Times cited : (108)

References (79)
  • 1
    • 0003572156 scopus 로고
    • Oxidative stress and antioxidant defenses in biology
    • (1995). In: Chapman and Hall, London
    • Ahmad, S. , Oxidative stress and antioxidant defenses in biology. (1995). In: Chapman and Hall, Oxidative Stress and Antioxidant Defenses in Biology, London, 1995.
    • (1995) Oxidative Stress and Antioxidant Defenses in Biology
    • Ahmad, S.1
  • 2
    • 0027171266 scopus 로고
    • In: Oxidants, antioxidants and the degenerative diseases of aging
    • Ames B.N., Shigenaga M.K., Hagen T.M. In Oxidants, antioxidants and the degenerative diseases of aging . Proc. Natl. Acad. Sci. USA. 90:1993;7915-7922.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 3
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker, J., , LIU, J.-P., ROBERTSON, E.J., and EFSTRATIADIS. A Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75, 73-82, 1993.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.-P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 4
    • 0030582463 scopus 로고    scopus 로고
    • Overexpression of bovine growth hormone in transgenic mice is associated with changes in hepatic insulin receptors and in their kinase activity
    • Balbis A., Bartke A., Turyn D. Overexpression of bovine growth hormone in transgenic mice is associated with changes in hepatic insulin receptors and in their kinase activity. Life Sci. 59:1996;1363-1371.
    • (1996) Life Sci , vol.59 , pp. 1363-1371
    • Balbis, A.1    Bartke, A.2    Turyn, D.3
  • 5
    • 0026681367 scopus 로고
    • Down regulation of masked and unmasked insulin receptors in the liver of transgenic mice expressing bovine growth hormone gene
    • Balbis A., Dellacha J.M., Calandra R.E.S., Bartke A., Turyn D. Down regulation of masked and unmasked insulin receptors in the liver of transgenic mice expressing bovine growth hormone gene. Life Sci. 51:1992;771-778.
    • (1992) Life Sci , vol.51 , pp. 771-778
    • Balbis, A.1    Dellacha, J.M.2    Calandra, R.E.S.3    Bartke, A.4    Turyn, D.5
  • 6
    • 0000046781 scopus 로고
    • Genetic models in the study of anterior pituitary hormones. Genetic models in the study of anterior pituitary hormones
    • Shire, J.G.M. (Editor), CRC Press, Boca Raton
    • Bartke, A. , Genetic models in the study of anterior pituitary hormones. Genetic models in the study of anterior pituitary hormones. In: Genetic Variation in Hormone Systems, Shire, J.G.M. (Editor), pp. 113-126, CRC Press, Boca Raton, 1979.
    • (1979) In: Genetic Variation in Hormone Systems , pp. 113-126
    • Bartke, A.1
  • 7
    • 0345146191 scopus 로고
    • Low mortality and long survival of dwarf mice (dw/dw)
    • Bartke A. Low mortality and long survival of dwarf mice (dw/dw). Mouse News Lett. 56:1977;63.
    • (1977) Mouse News Lett , vol.56 , pp. 63
    • Bartke, A.1
  • 8
    • 0013902106 scopus 로고
    • Reproduction of female dwarf mice treated with prolactin
    • Bartke A. Reproduction of female dwarf mice treated with prolactin. J. Reprod. Fertil. 11:1966;203-206.
    • (1966) J. Reprod. Fertil. , vol.11 , pp. 203-206
    • Bartke, A.1
  • 9
    • 0345577921 scopus 로고    scopus 로고
    • Neuroendocrine function, sexual behavior and fertility in transgenic mice expressing growth hormone genes
    • Waites, G.M.H., Frick, J., and Baker, G.W.H. (Editors), Proceedings of the VIth International Congress of Andrology, Salzburg
    • Bartke, A., Amador, A.G., Meliska, C.J., Yun, J.S., and Wagner, T.E. , Neuroendocrine function, sexual behavior and fertility in transgenic mice expressing growth hormone genes. In: Current Advances in Andrology, Waites, G.M.H., Frick, J., and Baker, G.W.H. (Editors), pp. 295-301, Proceedings of the VIth International Congress of Andrology, Salzburg, 1997.
    • (1997) In: Current Advances in Andrology , pp. 295-301
    • Bartke, A.1    Amador, A.G.2    Meliska, C.J.3    Yun, J.S.4    Wagner, T.E.5
  • 10
    • 0017643115 scopus 로고
    • Effects of prolactin (PRL) on pituitary and testicular function in mice with hereditary PRL deficiency
    • Bartke A., Goldman B.D., Bex F., Dalterio S. Effects of prolactin (PRL) on pituitary and testicular function in mice with hereditary PRL deficiency. Endocrinology. 101:1977;1760-1766.
    • (1977) Endocrinology , vol.101 , pp. 1760-1766
    • Bartke, A.1    Goldman, B.D.2    Bex, F.3    Dalterio, S.4
  • 12
    • 84966143698 scopus 로고
    • Carcinogenesis in the pituitary dwarf mouse. The response to dimethylbenzanthracene applied to the skin
    • Bielschowsky F., Bielschowsky M. Carcinogenesis in the pituitary dwarf mouse. The response to dimethylbenzanthracene applied to the skin. Br. J. Cancer. 15:1961;257.
    • (1961) Br. J. Cancer , vol.15 , pp. 257
    • Bielschowsky, F.1    Bielschowsky, M.2
  • 13
    • 0028788807 scopus 로고
    • Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse
    • Borg K.E., Brown-Borg H.M., Bartke A. Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse. Proc. Soc. Exp. Biol. Med. 210:1995;126-133.
    • (1995) Proc. Soc. Exp. Biol. Med. , vol.210 , pp. 126-133
    • Borg, K.E.1    Brown-Borg, H.M.2    Bartke, A.3
  • 14
    • 0023009451 scopus 로고
    • Aging as entropy
    • Bortz, W.M. , Aging as entropy Exp. Gerontol. 21, 321-328, 1986.
    • (1986) Exp. Gerontol. , vol.21 , pp. 321-328
    • Bortz, W.M.1
  • 15
    • 0025841730 scopus 로고
    • Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice
    • Bronson R.T., Lipman R.D. Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice. Growth Dev. Aging. 55:1991;169-184.
    • (1991) Growth Dev. Aging , vol.55 , pp. 169-184
    • Bronson, R.T.1    Lipman, R.D.2
  • 18
    • 0000703708 scopus 로고
    • Expression of human, but not bovine growth hormone genes promotes development of mammary tumors in transgenic mice
    • Cecim M., Bartke A., Yun J.S., Wagner T.E. Expression of human, but not bovine growth hormone genes promotes development of mammary tumors in transgenic mice. Transgenics. 1:1994;431-437.
    • (1994) Transgenics , vol.1 , pp. 431-437
    • Cecim, M.1    Bartke, A.2    Yun, J.S.3    Wagner, T.E.4
  • 20
    • 0028944077 scopus 로고
    • Effects of bovine growth hormone (bGH) transgene expression or bGH treatment on reproductive functions in female mice
    • Cecim M., Kerr J., Bartke A. Effects of bovine growth hormone (bGH) transgene expression or bGH treatment on reproductive functions in female mice. Biol. Reprod. 52:1995;1144-1148.
    • (1995) Biol. Reprod. , vol.52 , pp. 1144-1148
    • Cecim, M.1    Kerr, J.2    Bartke, A.3
  • 21
    • 0027500264 scopus 로고
    • Induction of endogenous insulin-like growth factor-I secretion alters the hypothalamic-pituitary-testicular function in growth hormone-deficient adult dwarf mice
    • Chandrashekar V., Bartke A. Induction of endogenous insulin-like growth factor-I secretion alters the hypothalamic-pituitary-testicular function in growth hormone-deficient adult dwarf mice. Biol. Reprod. 48:1993;544-551.
    • (1993) Biol. Reprod. , vol.48 , pp. 544-551
    • Chandrashekar, V.1    Bartke, A.2
  • 23
    • 0015419583 scopus 로고
    • Tumorigenesis in strain DW/J mice and induction by prolactin of the group-specific antigen of endogenous C-type RNA tumor virus
    • Chen H.W., Meier H., Heiniger H.-J., Huebner R.J. Tumorigenesis in strain DW/J mice and induction by prolactin of the group-specific antigen of endogenous C-type RNA tumor virus. J. Natl. Cancer Inst. 49:1972;1145.
    • (1972) J. Natl. Cancer Inst. , vol.49 , pp. 1145
    • Chen, H.W.1    Meier, H.2    Heiniger, H.-J.3    Huebner, R.J.4
  • 24
    • 0026377007 scopus 로고
    • Glycine 119 of bovine growth hormone is critical for growth-promoting activity
    • Chen W.Y., Wight D.C., Metha B.V., Wagner T.E., Kopchick J.J. Glycine 119 of bovine growth hormone is critical for growth-promoting activity. Mol. Endocrinol. 5:1991;1845-1852.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1845-1852
    • Chen, W.Y.1    Wight, D.C.2    Metha, B.V.3    Wagner, T.E.4    Kopchick, J.J.5
  • 25
    • 0030792968 scopus 로고    scopus 로고
    • Decrease of immunoreactive catalase protein in specific areas of ageing rat brain
    • Ciriolo M.R., Marasco M.R., Iannone M., Nisticò G., Rotillo G. Decrease of immunoreactive catalase protein in specific areas of ageing rat brain. Neurosci. Lett. 118:1997;21-24.
    • (1997) Neurosci. Lett. , vol.118 , pp. 21-24
    • Ciriolo, M.R.1    Marasco, M.R.2    Iannone, M.3    Nisticò, G.4    Rotillo, G.5
  • 28
    • 0028944463 scopus 로고
    • Clinical aspects of growth hormone deficiency in adults
    • Deboer, H., , BLOK, G.-J., and VAN DER VEEN, E.A. Clinical aspects of growth hormone deficiency in adults. Endocr. Rev. 16, 63-86, 1995.
    • (1995) Endocr. Rev. , vol.16 , pp. 63-86
    • Deboer, H.1    Blok, G.-J.2    Van Der Veen, E.A.3
  • 31
    • 0017366211 scopus 로고
    • Longevity and lifetime body weight in mice selected for rapid growth
    • Eklund J., Bradford C.E. Longevity and lifetime body weight in mice selected for rapid growth. Nature. 265:1977;48-49.
    • (1977) Nature , vol.265 , pp. 48-49
    • Eklund, J.1    Bradford, C.E.2
  • 32
    • 0025851287 scopus 로고
    • Ectopic pituitary transplants restore immunocompetence in Ames dwarf mice
    • Esquifino A.I., VillanúA M.A., Szary A., Yau J., Bartke A. Ectopic pituitary transplants restore immunocompetence in Ames dwarf mice. Acta Endocrinol. 125:1991;67-72.
    • (1991) Acta Endocrinol , vol.125 , pp. 67-72
    • Esquifino, A.I.1    Villanúa, M.A.2    Szary, A.3    Yau, J.4    Bartke, A.5
  • 33
    • 0018823104 scopus 로고
    • The effects of hypophysectomy and continuous food restriction, begun at ages 70 and 400 days, on collagen aging, prolactinemia, incidence of pathology and longevity in the male rat
    • Everitt A.V., Seedsman N.J., Jones F. The effects of hypophysectomy and continuous food restriction, begun at ages 70 and 400 days, on collagen aging, prolactinemia, incidence of pathology and longevity in the male rat. Mech. Aging Dev. 12:1980;161-172.
    • (1980) Mech. Aging Dev. , vol.12 , pp. 161-172
    • Everitt, A.V.1    Seedsman, N.J.2    Jones, F.3
  • 34
    • 0015529108 scopus 로고
    • Lymphocytes, hormones, and ageing
    • Fabris N., Pierpaoli W., Sorkin E. Lymphocytes, hormones, and ageing. Nature. 240:1972;557-559.
    • (1972) Nature , vol.240 , pp. 557-559
    • Fabris, N.1    Pierpaoli, W.2    Sorkin, E.3
  • 35
    • 0027446657 scopus 로고
    • Influence of prolactin and growth hormone on the activation of dwarf mouse lymphocytes in vivo
    • Gala R.R., Shevach E.M. Influence of prolactin and growth hormone on the activation of dwarf mouse lymphocytes in vivo. Proc. Soc. Exp. Biol. Med. 204:1993;224-230.
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.204 , pp. 224-230
    • Gala, R.R.1    Shevach, E.M.2
  • 36
    • 0027265595 scopus 로고
    • GHRH receptor of little mice contains a missense mutation in the extra-cellular domain that disrupts receptor function
    • Godfrey P., Rahal J., Beamer W., Copel N., Jenkins N., Mayo K.E. GHRH receptor of little mice contains a missense mutation in the extra-cellular domain that disrupts receptor function. Nat. Genet. 199:1993;227-232.
    • (1993) Nat. Genet. , vol.199 , pp. 227-232
    • Godfrey, P.1    Rahal, J.2    Beamer, W.3    Copel, N.4    Jenkins, N.5    Mayo, K.E.6
  • 38
    • 0000887888 scopus 로고
    • A mass budget for transgenic "supermice" engineered with extra rat growth hormone genes: Evidence for energetic limitation
    • Kajiura L.J., Rollo C.D. A mass budget for transgenic "supermice" engineered with extra rat growth hormone genes evidence for energetic limitation . Can. J. Zool. 72:1994;1010-1017.
    • (1994) Can. J. Zool. , vol.72 , pp. 1010-1017
    • Kajiura, L.J.1    Rollo, C.D.2
  • 39
    • 0026034877 scopus 로고
    • Age-related alterations of the growth hormone/insulin-like-growth-factor I axis
    • Kelijman M. Age-related alterations of the growth hormone/insulin-like-growth-factor I axis. J. Am. Geriatr. Soc. 39:1991;295-307.
    • (1991) J. Am. Geriatr. Soc. , vol.39 , pp. 295-307
    • Kelijman, M.1
  • 40
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura, K.D., Tissenbaum, H.A., Liu, Y., and Ruvkun, G. , daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946, 1997.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 42
    • 0025014024 scopus 로고
    • Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1
    • Li, S., Crenshaw, B.E., , III, RAWSON, E.J., SIMMONS, D.M., SWANSON, L.W., and ROSENFELD, M.G. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347, 528-533, 1990.
    • (1990) Nature , vol.347 , pp. 528-533
    • Li, S.1    Crenshaw, B.E.2    III Rawson, E.J.3    Simmons, D.M.4    Swanson, L.W.5    Rosenfeld, M.G.6
  • 43
    • 0023710510 scopus 로고
    • Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone releasing factor gene
    • Mayo K.E., Hammer R.E., Swanson L.W., Brinster R.L., Rosenfeld M.G., Evans R.M. Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone releasing factor gene. Mol. Endocrinol. 2:1988;606-612.
    • (1988) Mol. Endocrinol. , vol.2 , pp. 606-612
    • Mayo, K.E.1    Hammer, R.E.2    Swanson, L.W.3    Brinster, R.L.4    Rosenfeld, M.G.5    Evans, R.M.6
  • 44
    • 0023751235 scopus 로고
    • Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice
    • McGrane M.M., Devente J., Yun J.S., Bloom J., Park E., Wynshaw A., Wagner T., Rottman F.M., Hanson R.W. Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. J. Biol. Chem. 263:1988;11443-11451.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11443-11451
    • McGrane, M.M.1    Devente, J.2    Yun, J.S.3    Bloom, J.4    Park, E.5    Wynshaw, A.6    Wagner, T.7    Rottman, F.M.8    Hanson, R.W.9
  • 45
    • 0031193957 scopus 로고    scopus 로고
    • Inhibitory avoidance and appetitive learning in aged normal mice: Comparison with transgenic mice having elevated plasma growth hormone levels
    • Meliska C.J., Burke P.A., Bartke A., Jensen R.A. Inhibitory avoidance and appetitive learning in aged normal mice Comparison with transgenic mice having elevated plasma growth hormone levels . Neurobiol. Learn. Mem. 68:1997;1-12.
    • (1997) Neurobiol. Learn. Mem. , vol.68 , pp. 1-12
    • Meliska, C.J.1    Burke, P.A.2    Bartke, A.3    Jensen, R.A.4
  • 46
    • 0031196680 scopus 로고    scopus 로고
    • Potential applications of GH secretagogs in the evaluation and treatment of the age-related decline in growth hormone secretion
    • Merriam G.R., Buchner D.M., Prinz P.N., Schwartz R.S., Vitiello M.V. Potential applications of GH secretagogs in the evaluation and treatment of the age-related decline in growth hormone secretion. Endocrine. 7:1997;49-52.
    • (1997) Endocrine , vol.7 , pp. 49-52
    • Merriam, G.R.1    Buchner, D.M.2    Prinz, P.N.3    Schwartz, R.S.4    Vitiello, M.V.5
  • 47
    • 0029046938 scopus 로고
    • Increased glial fibrillary acidic protein (GFAP) levels in the brains of transgenic mice expressing the bovine growth hormone (bGH) gene
    • Miller, D.B., Bartke, A., , and O'CALLAGHAN, J.P. Increased glial fibrillary acidic protein (GFAP) levels in the brains of transgenic mice expressing the bovine growth hormone (bGH) gene. Exp. Gerontol. 30, 383-400, 1995.
    • (1995) Exp. Gerontol. , vol.30 , pp. 383-400
    • Miller, D.B.1    Bartke, A.2    O'Callaghan, J.P.3
  • 48
    • 0025880320 scopus 로고
    • Influence of age and caloric restriction on expression of hepatic genes for xenobiotic and oxygen metabolizing enzymes in the mouse
    • Mote, P.L., Grizzle, J.M., Walford, R.L., and Spindler, S.R. , Influence of age and caloric restriction on expression of hepatic genes for xenobiotic and oxygen metabolizing enzymes in the mouse. J. Gerontol. 46, B95-B100, 1991.
    • (1991) J. Gerontol. , vol.46
    • Mote, P.L.1    Grizzle, J.M.2    Walford, R.L.3    Spindler, S.R.4
  • 50
    • 0021075353 scopus 로고
    • Metallothionein-human growth hormone fusion genes stimulate growth of mice
    • Palmiter, R.D., Norstedt, G., Gelinas, R.E., Hammer, R.E., and Brinster, R.L. , Metallothionein-human growth hormone fusion genes stimulate growth of mice, Science 222, 809-814, 1983.
    • (1983) Science , vol.222 , pp. 809-814
    • Palmiter, R.D.1    Norstedt, G.2    Gelinas, R.E.3    Hammer, R.E.4    Brinster, R.L.5
  • 51
    • 0030992739 scopus 로고    scopus 로고
    • Comparative longevity of pet dogs and humans: Implications for gerontology research
    • Patronek G.J., Waters D.J., Glickman L.T. Comparative longevity of pet dogs and humans implications for gerontology research . J. Gerontol. 52A:1997;B171-B178.
    • (1997) J. Gerontol. , vol.52
    • Patronek, G.J.1    Waters, D.J.2    Glickman, L.T.3
  • 52
    • 0027203976 scopus 로고
    • Decrease in cellular replicative potential in giant mice transfected with the bovine growth hormone gene correlates to shortened life span
    • Pendergast W.R., Li Y., Jiang D., Wolf N.S. Decrease in cellular replicative potential in giant mice transfected with the bovine growth hormone gene correlates to shortened life span. J. Cell. Physiol. 156:1993;96-103.
    • (1993) J. Cell. Physiol. , vol.156 , pp. 96-103
    • Pendergast, W.R.1    Li, Y.2    Jiang, D.3    Wolf, N.S.4
  • 53
    • 0013826030 scopus 로고
    • A cumulative study of the growth of sarcoma 180 in anterior pituitary dwarf mice
    • Rennels E.G., Anigstein D.M., Anigstein L. A cumulative study of the growth of sarcoma 180 in anterior pituitary dwarf mice. Tex. Rep. Biol. Med. 23:1965;776.
    • (1965) Tex. Rep. Biol. Med. , vol.23 , pp. 776
    • Rennels, E.G.1    Anigstein, D.M.2    Anigstein, L.3
  • 54
    • 84966168931 scopus 로고
    • The lifetime growth and reproduction of selected strains of mice
    • Roberts R.C. The lifetime growth and reproduction of selected strains of mice. Heredity. 16:1961;369-381.
    • (1961) Heredity , vol.16 , pp. 369-381
    • Roberts, R.C.1
  • 55
    • 0000689299 scopus 로고    scopus 로고
    • Accelerated aging of giant transgenic mice is associated with elevated free radical processes
    • Rollo C.D., Carlson J., Sawada M. Accelerated aging of giant transgenic mice is associated with elevated free radical processes. Can. J. Zool. 74:1996;606-620.
    • (1996) Can. J. Zool. , vol.74 , pp. 606-620
    • Rollo, C.D.1    Carlson, J.2    Sawada, M.3
  • 56
    • 0030766632 scopus 로고    scopus 로고
    • Lifetime reproduction of giant transgenic mice: The energetic stress paradigm
    • Rollo C.D., Rintoul J., Kajiura L.J. Lifetime reproduction of giant transgenic mice The energetic stress paradigm . Can. J. Zool. 78:1997;1336-1345.
    • (1997) Can. J. Zool. , vol.78 , pp. 1336-1345
    • Rollo, C.D.1    Rintoul, J.2    Kajiura, L.J.3
  • 57
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • ROSEN, T. and Bengtsson, B.-A. , Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 336, 285-288, 1990.
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosen, T.1    Bengtsson, B.-A.2
  • 58
    • 7144262119 scopus 로고
    • Entropy theories of aging revisited
    • Roth, G.S. , Entropy theories of aging revisited Aging Clin. Exp. Res. 6, 139-140, 1994.
    • (1994) Aging Clin. Exp. Res. , vol.6 , pp. 139-140
    • Roth, G.S.1
  • 59
    • 0022370713 scopus 로고
    • Growth hormone, body composition and aging
    • Rudman D. Growth hormone, body composition and aging. J. Am. Geriatr. Soc. 33:1985;800-807.
    • (1985) J. Am. Geriatr. Soc. , vol.33 , pp. 800-807
    • Rudman, D.1
  • 63
    • 0017283923 scopus 로고
    • Immunological competence in Snell-Bagg pituitary dwarf mice: Response to the contact-sensitizing agent oxazolone
    • Schneider G.B. Immunological competence in Snell-Bagg pituitary dwarf mice Response to the contact-sensitizing agent oxazolone . Am. J. Anat. 145:1976;371-394.
    • (1976) Am. J. Anat. , vol.145 , pp. 371-394
    • Schneider, G.B.1
  • 65
    • 0015814124 scopus 로고
    • Growth hormone and premature ageing
    • Shire J.G.M. Growth hormone and premature ageing. Nature. 245:1973;215-216.
    • (1973) Nature , vol.245 , pp. 215-216
    • Shire, J.G.M.1
  • 66
    • 0019207594 scopus 로고
    • Decreased pulsatile release of growth hormone in old male rats
    • Sonntag E.W., Steger R.W., Forman J.L., Meites J. Decreased pulsatile release of growth hormone in old male rats. Endocrinology. 107:1980;1875-1879.
    • (1980) Endocrinology , vol.107 , pp. 1875-1879
    • Sonntag, E.W.1    Steger, R.W.2    Forman, J.L.3    Meites, J.4
  • 67
    • 0030795556 scopus 로고    scopus 로고
    • Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1
    • Sonntag W.E., Lynch C.D., Cooney P.T., Hutchins P.M. Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1. Endocrinology. 138:1997;3515-3520.
    • (1997) Endocrinology , vol.138 , pp. 3515-3520
    • Sonntag, W.E.1    Lynch, C.D.2    Cooney, P.T.3    Hutchins, P.M.4
  • 68
    • 0029042492 scopus 로고
    • Moderate caloric restriction alters the subcellular distribution of somatostatin mRNA and increases growth hormone pulse amplitude in aged animals
    • Sonntag W.E., Xu X., Ingram R.L., C'Costa A. Moderate caloric restriction alters the subcellular distribution of somatostatin mRNA and increases growth hormone pulse amplitude in aged animals. Reg. Growth Horm. 61:1995;601-608.
    • (1995) Reg. Growth Horm. , vol.61 , pp. 601-608
    • Sonntag, W.E.1    Xu, X.2    Ingram, R.L.3    C'Costa, A.4
  • 70
    • 0027345682 scopus 로고
    • Premature ageing in transgenic mice expressing growth hormone genes
    • Steger, R.W., Bartke, A., and Cecim, M. , Premature ageing in transgenic mice expressing growth hormone genes. J. Reprod. Fertil. Suppl. 46, 61-75, 1993.
    • (1993) J. Reprod. Fertil. , Issue.SUPPL. 46 , pp. 61-75
    • Steger, R.W.1    Bartke, A.2    Cecim, M.3
  • 71
    • 0027198110 scopus 로고
    • And de , VOS, A.M. Crystals of human growth hormone-receptor complexes. Extracellular domains of the growth hormone and prolactin receptors and a hormone mutant designed to prevent dimerization
    • Ultsch M. and de , VOS, A.M. Crystals of human growth hormone-receptor complexes. Extracellular domains of the growth hormone and prolactin receptors and a hormone mutant designed to prevent dimerization. J. Mol. Biol. 231:1993;1133-1136.
    • (1993) J. Mol. Biol. , vol.231 , pp. 1133-1136
    • Ultsch, M.1
  • 72
    • 0022461572 scopus 로고
    • Biosynthetic somatomedin C (SM-C/IGF-I) increases the length and weight of Snell dwarf mice
    • van Buul-Offers, S., Veda, I., and van den Brande, J.L., Biosynthetic somatomedin C (SM-C/IGF-I) increases the length and weight of Snell dwarf mice. Pediatr. Res. 20, 825-827, 1986.
    • (1986) Pediatr. Res. , vol.20 , pp. 825-827
    • Van Buul-Offers, S.1    Veda, I.2    Van Den Brande, J.L.3
  • 73
    • 0026743890 scopus 로고
    • The GH-transgenic mouse as an experimental model for growth research: Clinical and pathological studies
    • Wanke R., Wolf E., Hermanns W., Folger S., Buchmuller T., Brem G. The GH-transgenic mouse as an experimental model for growth research Clinical and pathological studies . Horm. Res. 37:1992;74-87.
    • (1992) Horm. Res. , vol.37 , pp. 74-87
    • Wanke, R.1    Wolf, E.2    Hermanns, W.3    Folger, S.4    Buchmuller, T.5    Brem, G.6
  • 74
  • 75
    • 85003056764 scopus 로고
    • Cellular growth in the organs of the hypopituitary dwarf mouse
    • Winick M., Grant P. Cellular growth in the organs of the hypopituitary dwarf mouse. Endocrinololgy. 83:1968;544-547.
    • (1968) Endocrinololgy , vol.83 , pp. 544-547
    • Winick, M.1    Grant, P.2
  • 76
    • 0001118049 scopus 로고    scopus 로고
    • Life time reproductive performance and functional changes in reproductive organs of mice selected divergently for body weight over 90 generations
    • Wirth-Dzieciolowska E., Czuminska K., Reklewska B., Katkiewicz M. Life time reproductive performance and functional changes in reproductive organs of mice selected divergently for body weight over 90 generations. Anim. Sci. Papers and Rep. 14:1996;187-198.
    • (1996) Anim. Sci. Papers and Rep. , vol.14 , pp. 187-198
    • Wirth-Dzieciolowska, E.1    Czuminska, K.2    Reklewska, B.3    Katkiewicz, M.4
  • 77
    • 0027178438 scopus 로고
    • Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models
    • Wolf E., Kahnt E., Ehrlein J., Hermanns W., Brem G., Wanke R. Effects of long-term elevated serum levels of growth hormone on life expectancy of mice Lessons from transgenic animal models . Mech. of Ageing and Dev. 68:1993;71-87.
    • (1993) Mech. of Ageing and Dev. , vol.68 , pp. 71-87
    • Wolf, E.1    Kahnt, E.2    Ehrlein, J.3    Hermanns, W.4    Brem, G.5    Wanke, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.