Effects of the Pit1 mutation on the insulin signaling pathway: Implications on the longevity of the long-lived Snell dwarf mouse

Mechanisms of Ageing and Development

Volumn 123, Issue 9, 2002, Pages 1245-1255

  Hsieh, Ching Chyuan ^a   DeFord, James H ^a   Flurkey, Kevin ^b   Harrison, David E ^b   Papaconstantinou, John ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

AKT; Insulin receptor; Insulin signaling; IRS 1; Liver; PI3K; Snell dwarf

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN P110; PROTEIN P85; SOMATOMEDIN BINDING PROTEIN 1; TRANSCRIPTION FACTOR PIT 1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GROWTH HORMONE DEFICIENCY; INSULIN BLOOD LEVEL; LIFESPAN; LIVER; LONGEVITY; MOUSE STRAIN; NEMATODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGING; ANIMALS; CAENORHABDITIS ELEGANS; DNA-BINDING PROTEINS; DWARFISM, PITUITARY; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LIVER; LONGEVITY; MICE; MICE, MUTANT STRAINS; MUTATION; PHOSPHOPROTEINS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0036111173     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(02)00037-4     Document Type: Article

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