Functional evaluation of tumour-specific variants of p16(INK4a)/CDKN2A: Correlation with protein structure information

Oncogene

Volumn 18, Issue 39, 1999, Pages 5423-5434

  Ruas, Margarida ^a   Brookes, Sharon ^a   McDonald, Neil Q ^a   Peters, Gordon ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Ankyrin repeats; Cyclin dependent kinase inhibitor; Familial melanoma; Replicative senescence; Tumour suppressor

Indexed keywords

COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; MUTANT PROTEIN; PROTEIN P16;

ARTICLE; ASSAY; CONTROLLED STUDY; ENZYME INHIBITOR INTERACTION; FIBROBLAST CULTURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RETROVIRUS; STRUCTURE ACTIVITY RELATION; TUMOR SUPPRESSOR GENE;

ALLELES; ANIMALS; BIOLOGICAL ASSAY; CELL DIVISION; CELLS, CULTURED; COS CELLS; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; EVALUATION STUDIES; HUMANS; MICE; MODELS, MOLECULAR; MUTATION; NEOPLASMS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; RETROVIRIDAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033598382     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202918     Document Type: Article

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