In vitro long-term cytotoxicity testing of 27 MEIC chemicals on Hep G2 cells and comparison with acute human toxicity data

Toxicology in Vitro

Volumn 15, Issue 2, 2001, Pages 153-161

  Scheers, E M ^a   Ekwall, Ba ^b   Dierickx, P J ^a  

^a PASTEUR INSTITUTE OF BRUSSELS   (Belgium)

^b CTLU   (Sweden)

Author keywords

Alternatives; Comparison to human toxicity data; EDIT; Hep G2; Long term cytotoxicity in vitro

Indexed keywords

ACETYLSALICYLIC ACID; ALCOHOL; AMITRIPTYLINE; AMPHETAMINE; ARSENIC DERIVATIVE; CAFFEINE; CELL PROTEIN; CHLORAMPHENICOL; COPPER SULFATE; DEXTROPROPOXYPHENE; DIAZEPAM; FERROUS SULFATE; FLUORIDE SODIUM; HEXACHLOROPHENE; ISONIAZID; LITHIUM SULFATE; MERCURIC CHLORIDE; ORPHENADRINE; PARACETAMOL; PENTACHLOROPHENOL; PHENOBARBITAL; POTASSIUM CYANIDE; PROPRANOLOL; QUINIDINE SULFATE; THEOPHYLLINE; THIORIDAZINE; VERAPAMIL; WARFARIN;

ARTICLE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOTOXICITY; HUMAN; HUMAN CELL;

CARCINOMA, HEPATOCELLULAR; HUMANS; LINEAR MODELS; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; TOXICITY TESTS; TUMOR CELLS, CULTURED;

EID: 0035080719     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(00)00062-X     Document Type: Article

References (12)

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11. Can the in vitro maximum tolerated dose be predicted using in vitro techniques A working hypothesis?