Isoprenylcysteine Carboxyl Methyltransferase Deficiency in Mice

Journal of Biological Chemistry

Volumn 276, Issue 8, 2001, Pages 5841-5845

  Bergo, Martin O ^a,e   Leung, Gordon K ^a,b   Ambroziak, Patricia ^a   Otto, James C ^c   Casey, Patrick J ^c   Gomes, Anita Q ^d   Seabra, Miguel C ^d   Young, Stephen G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^e GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; GENETIC ENGINEERING; TISSUE;

LATE GESTATION;

ENZYMES;

CAAX PROTEIN; METHYLTRANSFERASE; PROTEIN; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; RAS PROTEIN; RCE1 PROTEIN; UNCLASSIFIED DRUG; PROTEIN METHYLTRANSFERASE; PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE; PROTEINASE; RAB PROTEIN; RCE1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; ISOPRENYLATION; ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE DEFICIENCY; METHYLATION; MOUSE; NONHUMAN; ONCOGENE K RAS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; ANIMAL; BRAIN; EMBRYO DEATH; GENETICS; HETEROZYGOTE; HOMOZYGOTE; LETHAL GENE; METABOLISM; MOUSE MUTANT; PRENATAL DEVELOPMENT; PROTEIN PROCESSING; SKELETAL MUSCLE;

ANIMALIA;

ANIMALS; BRAIN; EMBRYO LOSS; ENDOPEPTIDASES; GENES, LETHAL; HETEROZYGOTE; HOMOZYGOTE; METHYLATION; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; PROTEIN ISOPRENYLATION; PROTEIN METHYLTRANSFERASES; RAB GTP-BINDING PROTEINS;

EID: 0035937112     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C000831200     Document Type: Article

References (28)

1. Young, S. G., Ambroziak, P., Kim, E., and Clarke, S. (2001) in The Enzymes (Tamanoi, F., and Sigman, D. G., eds), 3rd Ed., Vol. 21, pp. 156-213, Academic Press, San Diego, CA
2. Boyartchuk, V. L., Ashby, M. N., and Rine, J. (1997) Science 275, 1796-1800
3. Schmidt, W. K., Tam, A., Fujimura-Kamada, K., and Michaelis, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 11175-11180
4. Clarke, S., Vogel, J. P., Deschenes, R. J., and Stock, J. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 4643-4647
5. Dai, Q., Choy, E., Chiu, V., Romano, J., Slivka, S. R., Steitz, S. A., Michaelis, S., and Philips, M. R. (1998) J. Biol. Chem. 273, 15030-15034
6. Clarke, S. (1992) Annu. Rev. Biochem. 61, 355-386
7. Otto, J. C., Kim, E., Young, S. G., and Casey, P. J. (1999) J. Biol. Chem. 274, 8379-8382
8. Kim, E., Ambroziak, P., Otto, J. C., Taylor, B., Ashby, M., Shannon, K., Casey, P. J., and Young, S. G. (1999) J. Biol. Chem. 274, 8383-8390
9. Choy, E., Chiu, V. K., Silletti, J., Feoktistov, M., Morimoto, T., Michaelson, D., Ivanov, I. E., and Philips, M. R. (1999) Cell 98, 69-80
10. Bergo, M. O., Leung, G. K., Ambroziak, P., Otto, J. C., Casey, P. C., and Young, S. G. (2000) J. Biol. Chem. 275, 17605-17610
11. Giner, J.-L., and Rando, R. R. (1994) Biochemistry 33, 15116-15123
12. Smeland, T. E., Seabra, M. C., Goldstein, J. L., and Brown, M. S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10712-10716
13. Armstrong, S. A., Brown, M. S., Goldstein, J. L., and Seabra, M. C. (1995) Methods Enzymol. 257, 30-41
14. Cremers, F. P. M., Armstrong, S. A., Seabra, M. C., Brown, M. S., and Goldstein, J. L. (1994) J. Biol. Chem. 269, 2111-2117
15. Seabra, M. C., and James, G. L. (1998) Methods Mol. Biol. 84, 251-260
16. Pereira-Leal, J. B., Gomes, A. Q., and Seabra, M. C. (2001) Methods Mol. Biol., in press
17. Hrycyna, C. A., Sapperstein, S. K., Clarke, S., and Michaelis, S. (1991) EMBO J. 10, 1699-1709
18. Philips, M. R., Staud, R., Pillinger, M., Feoktistov, A., Volker, C., Stock, J. B., and Weissmann, G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2283-2287
19. Li, G., and Stahl, P. D. (1993) Arch. Biochem. Biophys. 304, 471-478
20. Farnsworth, C. C., Kawata, M., Yoshida, Y., Takai, Y., Gelb, M. H., and Glomset, J. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6196-6200
21. Newman, C. M. H., Giannakouros, T., Hancock, J. F., Fawell, E. H., Armstrong, J., and Magee, A. I. (1992) J. Biol. Chem. 267, 11329-11336
22. Giannakouros, T., Newman, C. M. H., Craighead, M. W., Armstrong, J., and Magee, A. I. (1993) J. Biol. Chem. 268, 24467-24474
23. Wei, C., Lutz, R., Sinensky, M., and Macara, I. G. (1992) Oncogene 7, 467-473
24. Parish, C. A., and Rando, R. R. (1996) Biochemistry 35, 8473-8477
25. Silvius, J. R., and l'Heureux, F. (1994) Biochemistry 33, 3014-3022
26. Chen, Z., Otto, J. C., Bergo, M. O., Young, S. G., and Casey, P. J. (2000) J. Biol. Chem. 275, 41251-41257
27. Fujimura-Kamada, K., Nouvet, F. J., and Michaelis, S. (1997) J. Cell Biol. 136, 271-285
28. Tam, A., Nouvet, F. J., Fujimura-Kamada, K., Slunt, H., Sisodia, S. S., and Michaelis, S. (1998) J. Cell Biol. 142, 635-649