NMR spectroscopy and protein structure determination: Applications to drug discovery and development

Current Pharmaceutical Biotechnology

Volumn 6, Issue 2, 2005, Pages 105-120

  Wishart, David ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Binding; Drug Discovery; Ligand; NMR; Protein; Spectroscopy; Structure

Indexed keywords

ALPHA INTERFERON; CYCLOPHILIN; DEFENSIN; EPIDERMAL GROWTH FACTOR; FK 506 BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; NEW DRUG; PRION PROTEIN; TRANSFORMING GROWTH FACTOR;

BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG RESEARCH; INTERMETHOD COMPARISON; MEDICAL TECHNOLOGY; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PEPTIDE MAPPING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; STRUCTURE ANALYSIS; VALIDATION PROCESS; X RAY CRYSTALLOGRAPHY;

COMPUTER SIMULATION; DRUG DESIGN; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEINS; SEQUENCE ANALYSIS, PROTEIN;

EID: 18344385532     PISSN: 13892010     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389201053642367     Document Type: Review

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