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Volumn 14, Issue SPEC. ISS. 1, 2005, Pages

Deregulated expression of Polycomb-group oncogenes in human malignant lymphomas and epithelial tumors

Author keywords

[No Author keywords available]

Indexed keywords

POLYCOMB GROUP PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 17444379015     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddi111     Document Type: Review
Times cited : (87)

References (94)
  • 1
    • 0036223508 scopus 로고    scopus 로고
    • Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy
    • Koga, H., Kaji, Y., Nishii, K., Shirai, M., Tomotsune, D., Osugi, T., Sawada, A., Kim, J.Y., Hara, J., Miwa, T. et al. (2002) Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy. Lab. Invest., 82, 375-385.
    • (2002) Lab. Invest. , vol.82 , pp. 375-385
    • Koga, H.1    Kaji, Y.2    Nishii, K.3    Shirai, M.4    Tomotsune, D.5    Osugi, T.6    Sawada, A.7    Kim, J.Y.8    Hara, J.9    Miwa, T.10
  • 2
    • 7544230144 scopus 로고    scopus 로고
    • The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
    • Caretti, G., Di Padova, M., Micales, B., Lyons, G.E. and Sartorelli, V. (2004) The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev. 18, 2627-2638.
    • (2004) Genes Dev. , vol.18 , pp. 2627-2638
    • Caretti, G.1    Di Padova, M.2    Micales, B.3    Lyons, G.E.4    Sartorelli, V.5
  • 3
    • 0029891279 scopus 로고    scopus 로고
    • A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton
    • Akasaka, T., Kanno, M., Balling, R., Mieza, M.A., Taniguchi, M. and Koseki, H. (1996) A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development, 122, 1513-1522.
    • (1996) Development , vol.122 , pp. 1513-1522
    • Akasaka, T.1    Kanno, M.2    Balling, R.3    Mieza, M.A.4    Taniguchi, M.5    Koseki, H.6
  • 4
    • 0028923508 scopus 로고
    • Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice
    • Alkema, M.J., van der Lugt, N.M., Bobeldijk, R.C., Berns, A. and van Lohuizen, M. (1995) Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice. Nature, 374, 724-727.
    • (1995) Nature , vol.374 , pp. 724-727
    • Alkema, M.J.1    van der Lugt, N.M.2    Bobeldijk, R.C.3    Berns, A.4    van Lohuizen, M.5
  • 8
    • 2342481623 scopus 로고    scopus 로고
    • Recent advances in X-chromosome inactivation
    • Heard, E. (2004) Recent advances in X-chromosome inactivation. Curr. Opin. Cell Biol., 16, 247-255.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 247-255
    • Heard, E.1
  • 9
    • 2342475666 scopus 로고    scopus 로고
    • Polycomb complexes and silencing mechanisms
    • Lund, A.H. and van Lohuizen, M. (2004) Polycomb complexes and silencing mechanisms. Curr. Opin. Cell Biol., 16, 239-246.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 239-246
    • Lund, A.H.1    van Lohuizen, M.2
  • 10
    • 0141785202 scopus 로고    scopus 로고
    • Gene repression by Polycomb group protein complexes: A distinct complex for every occasion?
    • Otte, A.P. and Kwaks, T.H. (2003) Gene repression by Polycomb group protein complexes: a distinct complex for every occasion? Curr. Opin. Genet. Dev., 13, 448-454.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 448-454
    • Otte, A.P.1    Kwaks, T.H.2
  • 11
    • 0842282841 scopus 로고    scopus 로고
    • Biochemical analysis of mammalian polycomb group protein complexes and the identification of genetic elements that block polycomb-mediated gene repression
    • Sewalt, R.G., Kwaks, T.H., Hamer, K. and Otte, A.P, (2004) Biochemical analysis of mammalian polycomb group protein complexes and the identification of genetic elements that block polycomb-mediated gene repression. Methods Enzymol., 377, 282-296.
    • (2004) Methods Enzymol. , vol.377 , pp. 282-296
    • Sewalt, R.G.1    Kwaks, T.H.2    Hamer, K.3    Otte, A.P.4
  • 12
    • 0037150730 scopus 로고    scopus 로고
    • Polycomb repression: From cellular memory to cellular proliferation and cancer
    • Jacobs, J.J. and van Lohuizen, M. (2002) Polycomb repression: from cellular memory to cellular proliferation and cancer. Biochim. Biophys. Acta, 1602, 151-161.
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 151-161
    • Jacobs, J.J.1    van Lohuizen, M.2
  • 13
    • 0037707818 scopus 로고    scopus 로고
    • Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis
    • Lessard, J. and Sauvageau, G. (2003) Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. Exp. Hematol., 31, 567-585.
    • (2003) Exp. Hematol. , vol.31 , pp. 567-585
    • Lessard, J.1    Sauvageau, G.2
  • 16
    • 3442876431 scopus 로고    scopus 로고
    • Distinct expression patterns of polycomb oncoproteins and their binding partners during the germinal center reaction
    • Van Galen, J.C., Dukers, D.F., Giroth, C., Sewalt, R.G., Otte, A.P., Meijer, C.J. and Raaphorst, F.M. (2004) Distinct expression patterns of polycomb oncoproteins and their binding partners during the germinal center reaction. Eur. J. Immunol., 34, 1870-1881.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1870-1881
    • Van Galen, J.C.1    Dukers, D.F.2    Giroth, C.3    Sewalt, R.G.4    Otte, A.P.5    Meijer, C.J.6    Raaphorst, F.M.7
  • 17
    • 0036668471 scopus 로고    scopus 로고
    • MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation
    • Akasaka, T., Takahashi, N., Suzuki, M., Koseki, H., Bodmer, R. and Koga, H. (2002) MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation. Genes Cells, 7, 835-850.
    • (2002) Genes Cells , vol.7 , pp. 835-850
    • Akasaka, T.1    Takahashi, N.2    Suzuki, M.3    Koseki, H.4    Bodmer, R.5    Koga, H.6
  • 18
    • 0032931768 scopus 로고    scopus 로고
    • C-terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins
    • Sewalt, R.G., Gunster, M.J., van der Vlag, J., Satijn, D.P. and Otte, A.P. (1999) C-terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Mol. Cell. Biol., 19, 777-787.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 777-787
    • Sewalt, R.G.1    Gunster, M.J.2    van der Vlag, J.3    Satijn, D.P.4    Otte, A.P.5
  • 19
    • 0035852632 scopus 로고    scopus 로고
    • The E2F6 transcription factor is a component of the mammalian Bmi1- containing polycomb complex
    • Trimarchi, J.M., Fairchild, B., Wen, J. and Lees, J.A. (2001) The E2F6 transcription factor is a component of the mammalian Bmi1- containing polycomb complex. Proc. Natl Acad. Sci. USA, 98, 1519-1524.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1519-1524
    • Trimarchi, J.M.1    Fairchild, B.2    Wen, J.3    Lees, J.A.4
  • 20
    • 2542618360 scopus 로고    scopus 로고
    • RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2
    • Qin, H., Wang, J., Liang, Y., Taniguchi, Y., Tanigaki, K. and Han, H. (2004) RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2. Nucleic Acids Res., 32, 1492-1501.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1492-1501
    • Qin, H.1    Wang, J.2    Liang, Y.3    Taniguchi, Y.4    Tanigaki, K.5    Han, H.6
  • 21
    • 0344223442 scopus 로고    scopus 로고
    • RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex and with the transcription factor YY1
    • Garcia, E., Marcos-Gutierrez, C., del Mar, L.M., Moreno, J.C. and Vidal, M. (1999) RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex and with the transcription factor YY1. EMBO J., 18, 3404-3418.
    • (1999) EMBO J. , vol.18 , pp. 3404-3418
    • Garcia, E.1    Marcos-Gutierrez, C.2    del Mar, L.M.3    Moreno, J.C.4    Vidal, M.5
  • 22
    • 0035945657 scopus 로고    scopus 로고
    • The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3
    • Garcia-Cuellar, M.P., Zilles, O., Schreiner, S.A., Birke, M., Winkler, T.H. and Slany, R.K. (2001) The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3. Oncogene, 20, 411-419.
    • (2001) Oncogene , vol.20 , pp. 411-419
    • Garcia-Cuellar, M.P.1    Zilles, O.2    Schreiner, S.A.3    Birke, M.4    Winkler, T.H.5    Slany, R.K.6
  • 23
    • 0033614357 scopus 로고    scopus 로고
    • SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co- localize with the human Polycomb group complex
    • Soulez, M., Saurin, A.J., Freemont, P.S. and Knight, J.C. (1999) SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co- localize with the human Polycomb group complex. Oncogene, 18 2739-2746.
    • (1999) Oncogene , vol.18 , pp. 2739-2746
    • Soulez, M.1    Saurin, A.J.2    Freemont, P.S.3    Knight, J.C.4
  • 25
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl, B.D. and Allis, C.D. (2000) The language of covalent histone modifications. Nature, 403, 41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 26
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • van der Vlag, J. and Otte, A.P. (1999) Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat. Genet., 23, 474-478.
    • (1999) Nat. Genet. , vol.23 , pp. 474-478
    • van der Vlag, J.1    Otte, A.P.2
  • 28
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein
    • Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P. and Reinberg, D. (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein. Genes Dev., 16, 2893-2905.
    • (2002) Genes Dev. , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 29
    • 1942502862 scopus 로고    scopus 로고
    • Different ezh2-containing complexes target methylation of histone h1 or nucleosomal histone h3
    • Kuzmichev, A., Jenuwein, T., Tempst, P. and Reinberg, D. (2004) Different ezh2-containing complexes target methylation of histone h1 or nucleosomal histone h3. Mol. Cell, 14, 183-193.
    • (2004) Mol. Cell , vol.14 , pp. 183-193
    • Kuzmichev, A.1    Jenuwein, T.2    Tempst, P.3    Reinberg, D.4
  • 30
    • 13244271351 scopus 로고    scopus 로고
    • Multiple activities contribute to Pc2 E3 function
    • Kagey, M.H., Melhuish, T.A., Powers, S.E. and Wotton, D. (2005) Multiple activities contribute to Pc2 E3 function. EMBO J., 24, 108-119.
    • (2005) EMBO J. , vol.24 , pp. 108-119
    • Kagey, M.H.1    Melhuish, T.A.2    Powers, S.E.3    Wotton, D.4
  • 31
    • 0036310641 scopus 로고    scopus 로고
    • Selective interactions between vertebrate Polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins
    • Sewalt, R.G., Lachner, M., Vargas, M., Hamer, K.M., den Blaauwen, J.L., Hendrix, T., Melcher, M., Schweizer, D., Jenuwein, T. and Otte, A.P. (2002) Selective interactions between vertebrate Polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins. Mol. Cell. Biol., 22, 5539-5553.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5539-5553
    • Sewalt, R.G.1    Lachner, M.2    Vargas, M.3    Hamer, K.M.4    den Blaauwen, J.L.5    Hendrix, T.6    Melcher, M.7    Schweizer, D.8    Jenuwein, T.9    Otte, A.P.10
  • 32
    • 11144237618 scopus 로고    scopus 로고
    • Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation
    • Fang, J., Chen, T., Chadwick, B., Li, E. and Zhang, Y. (2004) Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. J. Biol. Chem., 279, 52812-52815.
    • (2004) J. Biol. Chem. , vol.279 , pp. 52812-52815
    • Fang, J.1    Chen, T.2    Chadwick, B.3    Li, E.4    Zhang, Y.5
  • 36
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • Czermin, B., Melfi, R., McCabe, D., Seitz, V., Imhof, A. and Pirrotta, V. (2002) Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell, 111, 185-196.
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 37
    • 0035141264 scopus 로고    scopus 로고
    • The Drosophila Polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3
    • Tie, F., Furayama, T., Prasad-Sinha, J., Jane, E. and Harte, P.J. (2001) The Drosophila Polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3. Development, 128, 275-286.
    • (2001) Development , vol.128 , pp. 275-286
    • Tie, F.1    Furayama, T.2    Prasad-Sinha, J.3    Jane, E.4    Harte, P.J.5
  • 38
    • 6944253702 scopus 로고    scopus 로고
    • SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex
    • Furayama, T., Banerjee, R., Breen, T.R. and Harte, P.J. (2004) SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex. Curr. Biol., 14, 1812-1821.
    • (2004) Curr. Biol. , vol.14 , pp. 1812-1821
    • Furayama, T.1    Banerjee, R.2    Breen, T.R.3    Harte, P.J.4
  • 40
    • 8844259568 scopus 로고    scopus 로고
    • Epigenome changes in active and inactive polycomb-group-controlled regions
    • Breiling, A., O'Neill, L.P., D'Eliseo, D., Turner, B.M. and Orlando, V. (2004) Epigenome changes in active and inactive polycomb-group-controlled regions. EMBO Rep., 5, 976-982.
    • (2004) EMBO Rep. , vol.5 , pp. 976-982
    • Breiling, A.1    O'Neill, L.P.2    D'Eliseo, D.3    Turner, B.M.4    Orlando, V.5
  • 41
    • 8844219674 scopus 로고    scopus 로고
    • Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes
    • Ringrose, L., Ehret, H. and Paro, R. (2004) Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes. Mol. Cell, 16, 641-653.
    • (2004) Mol. Cell , vol.16 , pp. 641-653
    • Ringrose, L.1    Ehret, H.2    Paro, R.3
  • 42
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini, D., Bracken, A.P., Jensen, M.R., Denchi, E.L. and Helin, K. (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J., 23, 4061-4071.
    • (2004) EMBO J. , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Denchi, E.L.4    Helin, K.5
  • 43
    • 0035476530 scopus 로고    scopus 로고
    • Establishment of Polycomb silencing requires a transient interaction between PC and ESC
    • Poux, S., Melfi, R. and Pirrotta, V. (2001) Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Genes Dev., 15, 2509-2514.
    • (2001) Genes Dev. , vol.15 , pp. 2509-2514
    • Poux, S.1    Melfi, R.2    Pirrotta, V.3
  • 44
    • 0027487387 scopus 로고
    • bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis
    • Haupt, Y., Bath, M.L., Harris, A.W. and Adams, J.M. (1993) bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis. Oncogene, 8, 3161-3164.
    • (1993) Oncogene , vol.8 , pp. 3161-3164
    • Haupt, Y.1    Bath, M.L.2    Harris, A.W.3    Adams, J.M.4
  • 45
    • 0025863346 scopus 로고
    • Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
    • van Lohuizen, M., Verbeek, S., Scheijen, B., Wientjens, E., van der, G.H. and Berns, A. (1991) Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell, 65, 737-752.
    • (1991) Cell , vol.65 , pp. 737-752
    • van Lohuizen, M.1    Verbeek, S.2    Scheijen, B.3    Wientjens, E.4    van der, G.H.5    Berns, A.6
  • 46
    • 0025727771 scopus 로고
    • Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice
    • Haupt, Y., Alexander, W.S., Barri, G., Klinken, S.P. and Adams, J.M. (1991) Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell, 65, 753-763.
    • (1991) Cell , vol.65 , pp. 753-763
    • Haupt, Y.1    Alexander, W.S.2    Barri, G.3    Klinken, S.P.4    Adams, J.M.5
  • 47
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc- induced apoptosis via INK4a/ARF
    • Jacobs, J.J., Scheijen, B., Voncken, J.W., Kieboom, K., Berns, A. and van Lohuizen, M. (1999) Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc- induced apoptosis via INK4a/ARF. Genes Dev., 13, 2678-2690.
    • (1999) Genes Dev. , vol.13 , pp. 2678-2690
    • Jacobs, J.J.1    Scheijen, B.2    Voncken, J.W.3    Kieboom, K.4    Berns, A.5    van Lohuizen, M.6
  • 48
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs, J.J., Kieboom, K., Marino, S., DePinho, R.A. and van Lohuizen, M. (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature, 397, 164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 50
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken, A.P., Pasini, D., Capra, M., Prosperini, E., Colli, E. and Helin, K. (2003) EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J., 22 5323-5335.
    • (2003) EMBO J. , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 51
    • 4143054651 scopus 로고    scopus 로고
    • Activated p53 suppresses the histone methyltransferase EZH2 gene
    • Tang, X., Milyavsky, M., Shats, I., Erez, N., Goldfinger, N. and Rotter, V. (2004) Activated p53 suppresses the histone methyltransferase EZH2 gene. Oncogene, 23, 5759-5769.
    • (2004) Oncogene , vol.23 , pp. 5759-5769
    • Tang, X.1    Milyavsky, M.2    Shats, I.3    Erez, N.4    Goldfinger, N.5    Rotter, V.6
  • 54
    • 0035877978 scopus 로고    scopus 로고
    • Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma
    • van Kemenade, F.J., Raaphorst, F.M., Blokzijl, T., Fieret, E., Hamer, K.M., Satijn, D.P., Otte, A.P. and Meijer, C.J. (2001) Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. Blood, 97, 3896-3901.
    • (2001) Blood , vol.97 , pp. 3896-3901
    • van Kemenade, F.J.1    Raaphorst, F.M.2    Blokzijl, T.3    Fieret, E.4    Hamer, K.M.5    Satijn, D.P.6    Otte, A.P.7    Meijer, C.J.8
  • 55
    • 1542349930 scopus 로고    scopus 로고
    • Site-specific expression of Polycomb-group genes encoding the HPC-HPH/PRC1 complex in clinically defined primary nodal and cutaneous large B-cell lymphomas
    • Raaphorst, F.M., Vermeer, M., Fieret, E., Blokzijl, T., Dukers, D., Sewalt, R.G., Otte, A.P., Willemze, R. and Meijer, C.J. (2004) Site-specific expression of Polycomb-group genes encoding the HPC-HPH/PRC1 complex in clinically defined primary nodal and cutaneous large B-cell lymphomas. Am. J. Pathol., 164, 533-542.
    • (2004) Am. J. Pathol. , vol.164 , pp. 533-542
    • Raaphorst, F.M.1    Vermeer, M.2    Fieret, E.3    Blokzijl, T.4    Dukers, D.5    Sewalt, R.G.6    Otte, A.P.7    Willemze, R.8    Meijer, C.J.9
  • 61
    • 0035873747 scopus 로고    scopus 로고
    • Distinct bmi-1 and ezh2 expression patterns in thymocytes and mature t cells suggest a role for polycomb genes in human t cell differentiation
    • Raaphorst, F.M., Otte, A.P., van Kemenade, F.J., Blokzijl, T., Fieret, E., Hamer, K.M., Satijn, D.P. and Meijer, C.J. (2001) Distinct bmi-1 and ezh2 expression patterns in thymocytes and mature t cells suggest a role for polycomb genes in human t cell differentiation. J. Immunol., 166, 5925-5934.
    • (2001) J. Immunol. , vol.166 , pp. 5925-5934
    • Raaphorst, F.M.1    Otte, A.P.2    van Kemenade, F.J.3    Blokzijl, T.4    Fieret, E.5    Hamer, K.M.6    Satijn, D.P.7    Meijer, C.J.8
  • 62
    • 0033970457 scopus 로고    scopus 로고
    • Cutting edge: Polycomb gene expression patterns reflect distinct B cell differentiation stages in human germinal centers
    • Raaphorst, F.M., van Kemenade, F.J., Fieret, E., Hamer, K.M., Satijn, D.P., Otte, A.P. and Meijer, C.J. (2000) Cutting edge: polycomb gene expression patterns reflect distinct B cell differentiation stages in human germinal centers. J. Immunol., 164, 1-4.
    • (2000) J. Immunol. , vol.164 , pp. 1-4
    • Raaphorst, F.M.1    van Kemenade, F.J.2    Fieret, E.3    Hamer, K.M.4    Satijn, D.P.5    Otte, A.P.6    Meijer, C.J.7
  • 64
    • 0030034207 scopus 로고    scopus 로고
    • Treatment of primary cutaneous B-cell lymphomas of follicle center cell origin: A clinical follow-up study of 55 patients treated with radiotherapy or polychemotherapy
    • Rijlaarsdam, J.U., Toonstra, J., Meijer, O.W., Noordijk, E.M. and Willemze, R. (1996) Treatment of primary cutaneous B-cell lymphomas of follicle center cell origin: a clinical follow-up study of 55 patients treated with radiotherapy or polychemotherapy. J. Clin. Oncol., 14, 549-555.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 549-555
    • Rijlaarsdam, J.U.1    Toonstra, J.2    Meijer, O.W.3    Noordijk, E.M.4    Willemze, R.5
  • 66
    • 0029904075 scopus 로고    scopus 로고
    • Primary cutaneous large B-cell lymphomas of the legs. A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis
    • Dutch Cutaneous Lymphoma Working Group
    • Vermeer, M.H., Geelen, F.A., van Haselen, C.W., Voorst Vader, P.C., Geerts, M.L., van Vloten, W.A. and Willemze, R. (1996) Primary cutaneous large B-cell lymphomas of the legs. A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis. Dutch Cutaneous Lymphoma Working Group. Arch. Dermatol., 132, 1304-1308.
    • (1996) Arch. Dermatol. , vol.132 , pp. 1304-1308
    • Vermeer, M.H.1    Geelen, F.A.2    van Haselen, C.W.3    Voorst Vader, P.C.4    Geerts, M.L.5    van Vloten, W.A.6    Willemze, R.7
  • 71
    • 0028840713 scopus 로고
    • mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity
    • Kanno, M., Hasegawa, M., Ishida, A., Isono, K. and Taniguchi, M. (1995) mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. EMBO J., 14, 5672-5678.
    • (1995) EMBO J. , vol.14 , pp. 5672-5678
    • Kanno, M.1    Hasegawa, M.2    Ishida, A.3    Isono, K.4    Taniguchi, M.5
  • 73
    • 1842532206 scopus 로고    scopus 로고
    • Identification of discriminators of hepatoma by gene expression profiling using a minimal dataset approach
    • Neo, S.Y., Leow, C.K., Vega, V.B., Long, P.M., Islam, A.F., Lai, P.B., Liu, E.T. and Ren, E.C. (2004) Identification of discriminators of hepatoma by gene expression profiling using a minimal dataset approach. Hepatology, 39, 944-953.
    • (2004) Hepatology , vol.39 , pp. 944-953
    • Neo, S.Y.1    Leow, C.K.2    Vega, V.B.3    Long, P.M.4    Islam, A.F.5    Lai, P.B.6    Liu, E.T.7    Ren, E.C.8
  • 74
    • 9244265488 scopus 로고    scopus 로고
    • A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers
    • Wang, S., Robertson, G.P. and Zhu, J. (2004) A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers. Gene, 343, 69-78.
    • (2004) Gene , vol.343 , pp. 69-78
    • Wang, S.1    Robertson, G.P.2    Zhu, J.3
  • 77
    • 0035906853 scopus 로고    scopus 로고
    • The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression
    • Vonlanthen, S., Heighway, J., Altermatt, H.J., Gugger, M., Kappeler, A., Borner, M.M., Lohuizen, M. and Betticher, D.C. (2001) The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression. Br. J. Cancer 84, 1372-1376.
    • (2001) Br. J. Cancer , vol.84 , pp. 1372-1376
    • Vonlanthen, S.1    Heighway, J.2    Altermatt, H.J.3    Gugger, M.4    Kappeler, A.5    Borner, M.M.6    Lohuizen, M.7    Betticher, D.C.8
  • 78
    • 0141515537 scopus 로고    scopus 로고
    • Evidence for at least three alternative mechanisms targeting the p16INK4A/cyclin D/Rb pathway in penile carcinoma, one of which is mediated by high-risk human papillomavirus
    • Ferreux, E., Lont, A.P., Horenblas, S., Gallee, M.P., Raaphorst, F.M., Von Knebel, D.M., Meijer, C.J. and Snijders, P.J. (2003) Evidence for at least three alternative mechanisms targeting the p16INK4A/cyclin D/Rb pathway in penile carcinoma, one of which is mediated by high-risk human papillomavirus. J. Pathol., 201, 109-118.
    • (2003) J. Pathol. , vol.201 , pp. 109-118
    • Ferreux, E.1    Lont, A.P.2    Horenblas, S.3    Gallee, M.P.4    Raaphorst, F.M.5    Von Knebel, D.M.6    Meijer, C.J.7    Snijders, P.J.8
  • 81
    • 0346094301 scopus 로고    scopus 로고
    • The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins
    • Kim, J.H., Yoon, S.Y., Kim, C.N., Joo, J.H., Moon, S.K., Choe, I.S., Choe, Y.K. and Kim, J.W. (2004) The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins. Cancer Lett., 203, 217-224.
    • (2004) Cancer Lett. , vol.203 , pp. 217-224
    • Kim, J.H.1    Yoon, S.Y.2    Kim, C.N.3    Joo, J.H.4    Moon, S.K.5    Choe, I.S.6    Choe, Y.K.7    Kim, J.W.8
  • 82
    • 9244248707 scopus 로고    scopus 로고
    • Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer
    • Kim, J.H., Yoon, S.Y., Jeong, S.H., Kim, S.Y., Moon, S.K., Joo, J.H., Lee, Y., Choe, I.S. and Kim, J.W. (2004) Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer. Breast, 13, 383-388.
    • (2004) Breast , vol.13 , pp. 383-388
    • Kim, J.H.1    Yoon, S.Y.2    Jeong, S.H.3    Kim, S.Y.4    Moon, S.K.5    Joo, J.H.6    Lee, Y.7    Choe, I.S.8    Kim, J.W.9
  • 83
    • 0036682002 scopus 로고    scopus 로고
    • Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease
    • LaTulippe, E., Satagopan, J., Smith, A., Scher, H., Scardino, P., Reuter, V. and Gerald, W.L. (2002) Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Res., 62, 4499-4506.
    • (2002) Cancer Res. , vol.62 , pp. 4499-4506
    • LaTulippe, E.1    Satagopan, J.2    Smith, A.3    Scher, H.4    Scardino, P.5    Reuter, V.6    Gerald, W.L.7
  • 86
    • 0038002683 scopus 로고    scopus 로고
    • The EZH2 polycomb transcriptional repressor-A marker or mover of metastatic prostate cancer?
    • Sellers, W.R. and Loda, M. (2002) The EZH2 polycomb transcriptional repressor-a marker or mover of metastatic prostate cancer? Cancer Cell, 2, 349-350.
    • (2002) Cancer Cell , vol.2 , pp. 349-350
    • Sellers, W.R.1    Loda, M.2
  • 87
    • 4444362719 scopus 로고    scopus 로고
    • Epigenetic system: A pathway to malignancies and a therapeutic target
    • Nakao, M., Minami, T., Ueda, Y., Sakamoto, Y. and Ichimura, T. (2004) Epigenetic system: a pathway to malignancies and a therapeutic target. Int. J. Hematol., 80, 103-107.
    • (2004) Int. J. Hematol. , vol.80 , pp. 103-107
    • Nakao, M.1    Minami, T.2    Ueda, Y.3    Sakamoto, Y.4    Ichimura, T.5
  • 88
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger, G., Liang, G., Aparicio, A. and Jones, P.A. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature, 429, 457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 89
    • 1542325025 scopus 로고    scopus 로고
    • Identification and characterization of ASXL2 gene in silico
    • Katoh, M. and Katoh, M. (2003) Identification and characterization of ASXL2 gene in silico. Int. J. Oncol., 23, 845-850.
    • (2003) Int. J. Oncol. , vol.23 , pp. 845-850
    • Katoh, M.1    Katoh, M.2
  • 90
    • 0345700319 scopus 로고    scopus 로고
    • A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11
    • Fisher, C.L., Berger, J., Randazzo, F. and Brock, H.W. (2003) A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11. Gene, 306, 115-126.
    • (2003) Gene , vol.306 , pp. 115-126
    • Fisher, C.L.1    Berger, J.2    Randazzo, F.3    Brock, H.W.4
  • 91
    • 10344262019 scopus 로고    scopus 로고
    • Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tamour suppressor gene, in patients with myeloid malignancies
    • Bench, A.J., Li, J., Huntly, B.J., Delabesse, E., Fourouclas, N., Hunt, A.R., Deloukas, P. and Green, A.R. (2004) Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tamour suppressor gene, in patients with myeloid malignancies. Br. J. Haematol., 127, 509-518.
    • (2004) Br. J. Haematol. , vol.127 , pp. 509-518
    • Bench, A.J.1    Li, J.2    Huntly, B.J.3    Delabesse, E.4    Fourouclas, N.5    Hunt, A.R.6    Deloukas, P.7    Green, A.R.8
  • 92
    • 0034077361 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in carcinogenesis
    • Sugimura, T. and Ushijima, T. (2000) Genetic and epigenetic alterations in carcinogenesis. Mutat. Res., 462, 235-246.
    • (2000) Mutat. Res. , vol.462 , pp. 235-246
    • Sugimura, T.1    Ushijima, T.2
  • 93
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer; the polycomb connection
    • Valk-Lingbeek, M.E., Bruggeman, S.W. and van Lohuizen, M. (2004) Stem cells and cancer; the polycomb connection. Cell, 118 409-418.
    • (2004) Cell , vol.118 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.2    van Lohuizen, M.3
  • 94
    • 0141670822 scopus 로고    scopus 로고
    • Self-renewal of hematopoietic and leukemic stem cells: A central role for the Polycomb-group gene Bmi-1
    • Raaphorst, F.M. (2003) Self-renewal of hematopoietic and leukemic stem cells: a central role for the Polycomb-group gene Bmi-1. Trends Immunol., 24, 522-524.
    • (2003) Trends Immunol. , vol.24 , pp. 522-524
    • Raaphorst, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.